EP3302820A1 - Improved pump connecting the inside and the outside of a product vessel - Google Patents

Improved pump connecting the inside and the outside of a product vessel

Info

Publication number
EP3302820A1
EP3302820A1 EP16734413.4A EP16734413A EP3302820A1 EP 3302820 A1 EP3302820 A1 EP 3302820A1 EP 16734413 A EP16734413 A EP 16734413A EP 3302820 A1 EP3302820 A1 EP 3302820A1
Authority
EP
European Patent Office
Prior art keywords
pump
upstream end
labyrinth
product
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16734413.4A
Other languages
German (de)
French (fr)
Inventor
François Fauritte
Alain REGARD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nemera la Verpilliere SAS
Original Assignee
Nemera la Verpilliere SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nemera la Verpilliere SAS filed Critical Nemera la Verpilliere SAS
Publication of EP3302820A1 publication Critical patent/EP3302820A1/en
Pending legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10Valves; Arrangement of valves
    • F04B53/1002Ball valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0037Containers
    • B05B11/0039Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0041Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure without contact of the fluid remaining in the container with the atmospheric air
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00Devices for applying media, e.g. remedies, on the human body
    • A61M35/003Portable hand-held applicators having means for dispensing or spreading integral media
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1066Pump inlet valves
    • B05B11/1067Pump inlet valves actuated by pressure
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B9/00Piston machines or pumps characterised by the driving or driven means to or from their working members
    • F04B9/02Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical
    • F04B9/06Piston machines or pumps characterised by the driving or driven means to or from their working members the means being mechanical the means including spring- or weight-loaded lost-motion devices
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00Check valves
    • F16K15/02Check valves with guided rigid valve members
    • F16K15/04Check valves with guided rigid valve members shaped as balls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0059Components or details allowing operation in any orientation, e.g. for discharge in inverted position
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1073Springs
    • B05B11/1074Springs located outside pump chambers

Definitions

  • the invention relates to the field of pharmaceutical product dispensing devices.
  • a pharmaceutical reservoir for example a low viscosity liquid or gel used in the treatment of adult men with testosterone deficiency.
  • Document EP 1 578 537 discloses a pharmaceutical dispensing device provided with a pump intended to connect the inside and the outside of a pharmaceutical product reservoir. It comprises an upstream end product passage intended to extend in the reservoir and a ball check valve extending downstream of the upstream end, the valve moving between shutter and passage configurations. This device is intended to be used "head up”.
  • This device makes it possible to efficiently dispense the same dose of product as long as the reservoir is sufficiently full, but when the quantity of product remaining in the reservoir corresponds to only a few doses (end of life of the device), it is It can be seen that these are not as regular as the doses previously distributed.
  • the devices are packaged in cartons that can be stored in random orientations.
  • the device can be stored, before its first use by the patient, in a position in which the reservoir is found above the upstream end (when the device is "upside down” with respect to its position to distribute the product), so that the ball of the check valve is moved down under the effect of gravity and no longer fully constrains the passage of the upstream end.
  • This causes the air in the pump to progressively pass from the upstream end into the tank. If a majority of this air is expelled during the first use of the device, another party may be trapped at the bottom of the tank, and thus have an influence on the content of the last doses to be dispensed.
  • the purpose of the invention is to provide a pump intended to connect the interior and the outside of a product reservoir that ensures that the doses dispensed by the device will be more regular until the end of life of the device, and regardless of the amount of product in the tank and the conditions of storage of the device.
  • the subject of the invention is a pump intended to connect the inside and the outside of a pharmaceutical product reservoir comprising an upstream end of product passage intended to extend into the reservoir and to be in communication. fluidic with the reservoir and, downstream of the upstream end, a non-return valve moving between shutter and passage configurations,
  • upstream end is extended upstream by a member forming a labyrinth product passage, said labyrinth forming member.
  • labyrinth product passage means a passage in which the product therein must take a tortuous path out of it. Such a passage is configured to create a labyrinth effect, which is an effect of resistance to the flow of a fluid.
  • the air initially present in the pump during assembly of the product dispensing device comprising the pump will have no influence, or at least will be limited, on the amount of product to be dispensed.
  • the doses dispensed by the device will therefore be identical, whether the reservoir is full or almost empty product.
  • the upstream end is of tubular general shape.
  • the labyrinth member has a general bell shape.
  • the labyrinth member is provided with centering means with respect to the upstream end.
  • the centering means cooperate with the interior of the upstream end.
  • the centering means comprise centering stops distributed circumferentially inside the upstream end.
  • the centering means cooperate with the outside of the upstream end.
  • the centering means comprise centering stops distributed circumferentially around the upstream end.
  • the invention also relates to a pump and flexible pouch assembly forming a pharmaceutical reservoir, characterized in that the pump is according to the invention.
  • the invention also relates to a product dispensing device for pharmaceutical use comprising a pump, characterized in that this pump is according to the invention.
  • FIG. 1 is a perspective view of a pump of a pharmaceutical product dispensing device according to a first embodiment of the invention
  • FIG. 2 is an axial sectional view of the pump of FIG. 1;
  • FIG. 3 is a perspective view of the labyrinth member of the pump of Figure 1;
  • FIG. 4 is a view similar to that of FIG. 2 showing a pump according to a second embodiment of the invention
  • FIG. 5 is a view similar to that of FIG. 3 showing the labyrinth member of the pump of FIG. 4.
  • FIG. 1 shows a dispensing device 1 for a pharmaceutical product in the form of a low-viscosity liquid or gel. This is for example a liquid used in the treatment of adult men with testosterone deficiency.
  • the dispensing device 1 comprises a pump 2 actuated by a nozzle 3 for connecting the inside and outside of a tank (not shown), which is for example a flexible pouch containing the liquid or gel of low viscosity.
  • the pump 2 is provided with a body 4, a guide ring 5 and a piston 6 biased by a spring 7 bearing between the guide ring 5 and an upper stop 8 carried by the nozzle 3.
  • the pump 2 also comprises a low abutment 9 insulating, in a rest position of the nozzle 3, the inside of the body 4 from the outside.
  • the pump 2 comprises an upstream product passage end 10 intended to extend into the reservoir and to be in fluid communication therewith.
  • the upstream end 10 is of tubular general shape.
  • FIGS. 2 and 4 show the dispensing device 1 in the position of use, or "head up", that is to say in a position in which the reservoir is intended to be below the upstream end 10.
  • head up that is to say in a position in which the reservoir is intended to be below the upstream end 10.
  • the pump 2 comprises, downstream of the upstream end 10, a non-return valve 11, for example a non-return ball valve 12.
  • the non-return valve 11 is able to evolve between shutter and passage configurations of the upstream end 10.
  • the non-return valve 11 is shown in its shutter configuration, corresponding to the position in which the ball 12 closes the passage of the upstream end 10.
  • the upstream end 10 is extended upstream, that is to say downwards of Figures 2 and 4, by a member 13 forming labyrinth product, said labyrinth forming member.
  • the labyrinth member 13 has a general bell shape.
  • the labyrinth member 13 may cover a variable length of the upstream end 10, and is not limited to that of the illustrated examples.
  • the air contained in the pump 2 which could possibly pass between the ball 12 and the wall 14 of the upstream end 10 serving as a seat to the ball 12, must take the labyrinth passage formed by the bell-shaped labyrinth member 13 before reaching the tank.
  • the labyrinth member 13 is provided with centering means 15 with respect to the upstream end 10.
  • the centering means 15 cooperate with the outside of the upstream end 10 (see in particular Figure 2).
  • the centering means 15 comprise centering stops 16 intended to be distributed circumferentially around the upstream end 10.
  • centering stops 16 are integral with the inner face 17 of an annular wall 18 of the labyrinth member 13.
  • the centering stops 16 are four in number and are uniformly distributed on the internal face 17 of the annular wall 18 of the labyrinth member 13.
  • the centering abutments 16 are for example two, three, five in number and uniformly distributed on the inner face 17 of the annular wall 18. Note however that the centering stops 16 are not necessarily distributed. uniformly on the inner face 17 of the annular wall 18.
  • the centering means 15 cooperate with the inside of the upstream end 10 (see in particular FIG. 4).
  • the centering means 15 comprise centering stops 16 intended to be distributed circumferentially inside the upstream end 10.
  • the centering stops 16 form a four-pointed star centered on the axis of the labyrinth member 13.
  • centering stops 16 form a star comprising a different number of branches, for example three, five or six.
  • centering stops are not necessarily evenly distributed around the axis of symmetry of the labyrinth member nor centered on the axis of the labyrinth member.

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)

Abstract

The invention relates to a pump (2) intended for connecting the inside and the outside of a product vessel for pharmaceutical use including an upstream end (10) for passing a product intended for extending into the vessel and for being in fluid communication with the vessel and, downstream from the upstream end (10), a check valve switching between configurations for sealing and passing a product. The upstream end (10) is extended upstream by a member (13) forming a passage of a product in a labyrinth, referred to as labyrinth-forming member.

Description

Pompe reliant l'intérieur et l'extérieur d'un réservoir de produit améliorée  Pump connecting the inside and the outside of an improved product tank
L'invention concerne le domaine des dispositifs de distribution de produit pharmaceutique. The invention relates to the field of pharmaceutical product dispensing devices.
Elle concerne plus particulièrement les pompes destinées à relier l'intérieur et l'extérieur d'un réservoir de produit pharmaceutique, par exemple un liquide ou gel de faible viscosité utilisé dans le traitement d'hommes adultes ayant un déficit en testostérone.  More particularly, it relates to pumps for connecting the interior and exterior of a pharmaceutical reservoir, for example a low viscosity liquid or gel used in the treatment of adult men with testosterone deficiency.
Il est important, dans le traitement de certaines maladies, de s'assurer que la quantité de produit pharmaceutique distribuée par un dispositif de distribution à pompe de ce produit, ou dose à distribuer, soit toujours sensiblement identique.  It is important, in the treatment of certain diseases, to ensure that the quantity of pharmaceutical product dispensed by a pump dispensing device of this product, or dose to be dispensed, is always substantially identical.
Dans ce qui suit, on qualifie un élément d'amont ou d'aval en fonction du sens de l'écoulement du produit lors de sa distribution dans cet élément.  In what follows, it qualifies an upstream or downstream element depending on the direction of flow of the product during its distribution in this element.
On connaît du document EP 1 578 537 un dispositif de distribution de produit pharmaceutique muni d'une pompe destinée à relier l'intérieur et l'extérieur d'un réservoir de produit pharmaceutique. Il comporte une extrémité amont de passage de produit destinée à s'étendre dans le réservoir et un clapet anti-retour à bille s'étendant en aval de l'extrémité amont, le clapet évoluant entre des configurations d'obturation et de passage. Ce dispositif est destiné à être utilisé « tête en haut ».  Document EP 1 578 537 discloses a pharmaceutical dispensing device provided with a pump intended to connect the inside and the outside of a pharmaceutical product reservoir. It comprises an upstream end product passage intended to extend in the reservoir and a ball check valve extending downstream of the upstream end, the valve moving between shutter and passage configurations. This device is intended to be used "head up".
Ce dispositif permet de distribuer efficacement une même dose de produit tant que le réservoir est suffisamment plein, mais lorsque la quantité de produit restante dans le réservoir ne correspond plus qu'à quelques doses (on parle de fin de vie du dispositif), on s'aperçoit que celles-ci ne sont pas aussi régulières que les doses distribuées précédemment.  This device makes it possible to efficiently dispense the same dose of product as long as the reservoir is sufficiently full, but when the quantity of product remaining in the reservoir corresponds to only a few doses (end of life of the device), it is It can be seen that these are not as regular as the doses previously distributed.
En effet, lors du montage initial du dispositif, de l'air est retenu dans la pompe. Par la suite, les dispositifs sont conditionnés dans des cartons qui peuvent être stockés dans des orientations aléatoires.  Indeed, during the initial assembly of the device, air is retained in the pump. Subsequently, the devices are packaged in cartons that can be stored in random orientations.
De ce fait, le dispositif peut être stocké, avant sa première utilisation par le patient, dans une position dans laquelle le réservoir se retrouve au-dessus de l'extrémité amont (lorsque le dispositif est « tête en bas » par rapport à sa position permettant de distribuer le produit), ce qui fait que la bille du clapet anti-retour est déplacée vers le bas sous l'effet de la gravité et n'obture plus totalement le passage de l'extrémité amont. Ceci a pour effet que l'air contenu dans la pompe parvient progressivement à passer, depuis l'extrémité amont, jusque dans le réservoir. Si une majorité de cet air est expulsée lors de la première utilisation du dispositif, une autre partie peut se retrouver piégée au fond du réservoir, et ainsi avoir une influence sur le contenu des dernières doses à distribuer.  Therefore, the device can be stored, before its first use by the patient, in a position in which the reservoir is found above the upstream end (when the device is "upside down" with respect to its position to distribute the product), so that the ball of the check valve is moved down under the effect of gravity and no longer fully constrains the passage of the upstream end. This causes the air in the pump to progressively pass from the upstream end into the tank. If a majority of this air is expelled during the first use of the device, another party may be trapped at the bottom of the tank, and thus have an influence on the content of the last doses to be dispensed.
L'invention a pour but de fournir une pompe destinée à relier l'intérieur et l'extérieur d'un réservoir de produit qui permette d'assurer que les doses distribuées par le dispositif seront plus régulières jusqu'à la fin de vie du dispositif, et ce quelle que soit la quantité de produit dans le réservoir et les conditions de stockage du dispositif. The purpose of the invention is to provide a pump intended to connect the interior and the outside of a product reservoir that ensures that the doses dispensed by the device will be more regular until the end of life of the device, and regardless of the amount of product in the tank and the conditions of storage of the device.
A cet effet, l'invention a pour objet une pompe destinée à relier l'intérieur et l'extérieur d'un réservoir de produit pharmaceutique comportant une extrémité amont de passage de produit destinée à s'étendre dans le réservoir et à être en communication fluidique avec le réservoir et, en aval de l'extrémité amont, un clapet anti-retour évoluant entre des configurations d'obturation et de passage,  For this purpose, the subject of the invention is a pump intended to connect the inside and the outside of a pharmaceutical product reservoir comprising an upstream end of product passage intended to extend into the reservoir and to be in communication. fluidic with the reservoir and, downstream of the upstream end, a non-return valve moving between shutter and passage configurations,
caractérisée en ce que l'extrémité amont est prolongée en amont par un organe formant un passage de produit en labyrinthe, dit organe formant labyrinthe.  characterized in that the upstream end is extended upstream by a member forming a labyrinth product passage, said labyrinth forming member.
On entend par « passage de produit en labyrinthe » un passage dans lequel le produit qui s'y trouve doit emprunter un chemin tortueux pour en sortir. Un tel passage est configuré pour créer un effet dit de labyrinthe, qui un effet de résistance à l'écoulement d'un fluide.  The term "labyrinth product passage" means a passage in which the product therein must take a tortuous path out of it. Such a passage is configured to create a labyrinth effect, which is an effect of resistance to the flow of a fluid.
On observe que, grâce à la présence de l'organe formant labyrinthe prolongeant l'extrémité amont de la pompe, le passage de l'air retenu initialement dans la pompe depuis cette pompe vers le réservoir est limité, voire empêché, par l'effet de labyrinthe.  It is observed that, thanks to the presence of the labyrinth member extending the upstream end of the pump, the passage of air initially retained in the pump from this pump to the reservoir is limited or prevented by the effect of labyrinth.
Ainsi, l'air présent initialement dans la pompe lors du montage du dispositif de distribution de produit comportant la pompe, n'aura pas d'influence, ou tout du moins sera-t-elle limitée, sur la quantité de produit à distribuer. Les doses distribuées par le dispositif seront donc identiques, que le réservoir soit plein ou quasi-vide en produit.  Thus, the air initially present in the pump during assembly of the product dispensing device comprising the pump, will have no influence, or at least will be limited, on the amount of product to be dispensed. The doses dispensed by the device will therefore be identical, whether the reservoir is full or almost empty product.
Dans un mode de réalisation particulier de l'invention, l'extrémité amont est de forme générale tubulaire.  In a particular embodiment of the invention, the upstream end is of tubular general shape.
Dans un mode de réalisation particulier de l'invention, l'organe formant labyrinthe a une forme générale de cloche.  In a particular embodiment of the invention, the labyrinth member has a general bell shape.
Dans un mode de réalisation particulier de l'invention, l'organe formant labyrinthe est muni de moyens de centrage par rapport à l'extrémité amont.  In a particular embodiment of the invention, the labyrinth member is provided with centering means with respect to the upstream end.
Dans un mode de réalisation particulier de l'invention, les moyens de centrage coopèrent avec l'intérieur de l'extrémité amont.  In a particular embodiment of the invention, the centering means cooperate with the interior of the upstream end.
Dans un mode de réalisation particulier de l'invention, les moyens de centrage comportent des butées de centrage réparties circonférentiellement à l'intérieur de l'extrémité amont.  In a particular embodiment of the invention, the centering means comprise centering stops distributed circumferentially inside the upstream end.
Dans un mode de réalisation particulier de l'invention, les moyens de centrage coopèrent avec l'extérieur de l'extrémité amont.  In a particular embodiment of the invention, the centering means cooperate with the outside of the upstream end.
Dans un mode de réalisation particulier de l'invention, les moyens de centrage comportent des butées de centrage réparties circonférentiellement autour de l'extrémité amont. L'invention concerne également un ensemble de pompe et de poche souple formant réservoir de produit pharmaceutique, caractérisé en ce que la pompe est selon l'invention. In a particular embodiment of the invention, the centering means comprise centering stops distributed circumferentially around the upstream end. The invention also relates to a pump and flexible pouch assembly forming a pharmaceutical reservoir, characterized in that the pump is according to the invention.
L'invention concerne également un dispositif de distribution de produit à usage pharmaceutique comprenant une pompe, caractérisé en ce que cette pompe est selon l'invention.  The invention also relates to a product dispensing device for pharmaceutical use comprising a pump, characterized in that this pump is according to the invention.
L'invention sera mieux comprise à la lecture de la description qui va suivre des figures annexées, qui sont fournies à titre d'exemples et ne présentent aucun caractère limitatif, dans lesquelles :  The invention will be better understood on reading the following description of the appended figures, which are provided by way of examples and are in no way limiting, in which:
- la figure 1 est une vue en perspective d'une pompe d'un dispositif de distribution de produit pharmaceutique selon un premier mode de réalisation de l'invention ;  FIG. 1 is a perspective view of a pump of a pharmaceutical product dispensing device according to a first embodiment of the invention;
- la figure 2 est une vue en coupe axiale de la pompe de la figure 1 ;  FIG. 2 is an axial sectional view of the pump of FIG. 1;
- la figure 3 est une vue en perspective de l'organe formant labyrinthe de la pompe de la figure 1 ;  Figure 3 is a perspective view of the labyrinth member of the pump of Figure 1;
- la figure 4 est une vue similaire à celle de la figure 2 montrant une pompe selon un deuxième mode de réalisation de l'invention ;  FIG. 4 is a view similar to that of FIG. 2 showing a pump according to a second embodiment of the invention;
- la figure 5 est une vue similaire à celle de la figure 3 montrant l'organe formant labyrinthe de la pompe de la figure 4.  FIG. 5 is a view similar to that of FIG. 3 showing the labyrinth member of the pump of FIG. 4.
On a représenté à la figure 1 un dispositif de distribution 1 de produit pharmaceutique sous forme de liquide ou gel à faible viscosité. Il s'agit par exemple d'un liquide utilisé dans le traitement d'hommes adultes ayant un déficit en testostérone.  FIG. 1 shows a dispensing device 1 for a pharmaceutical product in the form of a low-viscosity liquid or gel. This is for example a liquid used in the treatment of adult men with testosterone deficiency.
Comme on peut le voir sur les figures 2 et 4, le dispositif de distribution 1 comprend une pompe 2 actionnée par un gicleur 3 destinée à relier l'intérieur et l'extérieur d'un réservoir (non représenté), qui est par exemple une poche souple contenant le liquide ou gel de faible viscosité. La pompe 2 est pourvue d'un corps 4, d'une bague de guidage 5 et d'un piston 6 sollicité par un ressort 7 en appui entre la bague de guidage 5 et une butée haute 8 portée par le gicleur 3. La pompe 2 comporte également une butée basse 9 isolant, en une position de repos du gicleur 3, l'intérieur du corps 4 de l'extérieur.  As can be seen in Figures 2 and 4, the dispensing device 1 comprises a pump 2 actuated by a nozzle 3 for connecting the inside and outside of a tank (not shown), which is for example a flexible pouch containing the liquid or gel of low viscosity. The pump 2 is provided with a body 4, a guide ring 5 and a piston 6 biased by a spring 7 bearing between the guide ring 5 and an upper stop 8 carried by the nozzle 3. The pump 2 also comprises a low abutment 9 insulating, in a rest position of the nozzle 3, the inside of the body 4 from the outside.
Dans ce qui suit, on qualifie un élément d'amont ou d'aval en fonction du sens de l'écoulement du produit lors de sa distribution dans cet élément.  In what follows, it qualifies an upstream or downstream element depending on the direction of flow of the product during its distribution in this element.
La pompe 2 comprend une extrémité amont 10 de passage de produit destinée à s'étendre dans le réservoir et à être en communication fluidique avec celui-ci. L'extrémité amont 10 est de forme générale tubulaire.  The pump 2 comprises an upstream product passage end 10 intended to extend into the reservoir and to be in fluid communication therewith. The upstream end 10 is of tubular general shape.
Sur les figures 2 et 4, on a représenté le dispositif de distribution 1 en position d'utilisation, ou « tête en haut », c'est-à-dire dans une position dans laquelle le réservoir est destiné à se trouver en-dessous de l'extrémité amont 10. Ainsi, sur les figures 2 et 4, le sens amont est dirigé vers le bas des figures et le sens aval vers le haut des figures. FIGS. 2 and 4 show the dispensing device 1 in the position of use, or "head up", that is to say in a position in which the reservoir is intended to be below the upstream end 10. Thus, in Figures 2 and 4, the upstream direction is directed downwards of the figures and the upstream direction of the figures.
La pompe 2 comprend, en aval de l'extrémité amont 10, un clapet anti-retour 11 , par exemple un clapet anti-retour à bille 12.  The pump 2 comprises, downstream of the upstream end 10, a non-return valve 11, for example a non-return ball valve 12.
Le clapet anti-retour 11 est apte à évoluer entre des configurations d'obturation et de passage de l'extrémité amont 10. Sur les figures 2 et 4, le clapet anti-retour 11 est représenté dans sa configuration d'obturation, correspondant à la position dans laquelle la bille 12 obture le passage de l'extrémité amont 10.  The non-return valve 11 is able to evolve between shutter and passage configurations of the upstream end 10. In FIGS. 2 and 4, the non-return valve 11 is shown in its shutter configuration, corresponding to the position in which the ball 12 closes the passage of the upstream end 10.
L'extrémité amont 10 est prolongée en amont, c'est-à-dire vers le bas des figures 2 et 4, par un organe 13 formant passage de produit en labyrinthe, dit organe formant labyrinthe.  The upstream end 10 is extended upstream, that is to say downwards of Figures 2 and 4, by a member 13 forming labyrinth product, said labyrinth forming member.
Dans les exemples illustrés, l'organe formant labyrinthe 13 a une forme générale de cloche.  In the illustrated examples, the labyrinth member 13 has a general bell shape.
L'organe formant labyrinthe 13 peut recouvrir une longueur variable de l'extrémité amont 10, et ne se limite pas à celle des exemples illustrés.  The labyrinth member 13 may cover a variable length of the upstream end 10, and is not limited to that of the illustrated examples.
Du fait de la présence de l'organe formant labyrinthe 13 prolongeant l'extrémité amont 10, l'air contenu dans la pompe 2, qui pourrait éventuellement passer entre la bille 12 et la paroi 14 de l'extrémité amont 10 servant de siège à la bille 12, doit emprunter le passage en labyrinthe formé par la forme en cloche de l'organe formant labyrinthe 13 avant d'atteindre le réservoir.  Due to the presence of the labyrinth member 13 extending the upstream end 10, the air contained in the pump 2, which could possibly pass between the ball 12 and the wall 14 of the upstream end 10 serving as a seat to the ball 12, must take the labyrinth passage formed by the bell-shaped labyrinth member 13 before reaching the tank.
Ainsi, lorsque le dispositif de distribution 1 est placé « tête en bas » et que la bille 12 du clapet anti-retour 11 est déplacée vers le bas sous l'effet de la gravité, l'air contenu dans la pompe 2 qui pourrait éventuellement s'introduire dans le passage de l'extrémité amont 10 ne parvient pas dans le réservoir, ou uniquement de façon limitée.  Thus, when the dispensing device 1 is placed "upside down" and that the ball 12 of the nonreturn valve 11 is moved downwards under the effect of gravity, the air contained in the pump 2 which could possibly to enter the passage of the upstream end 10 does not reach the tank, or only in a limited way.
Dans les deux modes de réalisations présentés sur les figures, l'organe formant labyrinthe 13 est muni de moyens de centrage 15 par rapport à l'extrémité amont 10.  In the two embodiments shown in the figures, the labyrinth member 13 is provided with centering means 15 with respect to the upstream end 10.
Dans un premier mode de réalisation de l'invention présenté aux figures 2 et 3, les moyens de centrage 15 coopèrent avec l'extérieur de l'extrémité amont 10 (voir notamment la figure 2).  In a first embodiment of the invention shown in Figures 2 and 3, the centering means 15 cooperate with the outside of the upstream end 10 (see in particular Figure 2).
A cet effet, comme on peut le voir à la figure 3 représentant l'organe formant labyrinthe 13 seul, les moyens de centrage 15 comportent des butées de centrage 16 destinées à être réparties circonférentiellement autour de l'extrémité amont 10.  For this purpose, as can be seen in FIG. 3, representing the labyrinth member 13 alone, the centering means 15 comprise centering stops 16 intended to be distributed circumferentially around the upstream end 10.
Par exemple, les butées de centrage 16 sont venues de matière avec la face interne 17 d'une paroi annulaire 18 de l'organe formant labyrinthe 13.  For example, the centering stops 16 are integral with the inner face 17 of an annular wall 18 of the labyrinth member 13.
Dans le mode de réalisation particulier représenté sur la figure 3, les butées de centrage 16 sont au nombre de quatre, et sont réparties uniformément sur la face interne 17 de la paroi annulaire 18 de l'organe formant labyrinthe 13. Dans des variantes non représentées, les butées de centrage 16 sont par exemple au nombre de deux, trois, cinq et réparties uniformément sur la face interne 17 de la paroi annulaire 18. On notera toutefois que les butées de centrage 16 ne sont pas nécessairement réparties uniformément sur la face interne 17 de la paroi annulaire 18. In the particular embodiment shown in FIG. 3, the centering stops 16 are four in number and are uniformly distributed on the internal face 17 of the annular wall 18 of the labyrinth member 13. In variants not shown, the centering abutments 16 are for example two, three, five in number and uniformly distributed on the inner face 17 of the annular wall 18. Note however that the centering stops 16 are not necessarily distributed. uniformly on the inner face 17 of the annular wall 18.
Dans un deuxième mode de réalisation de l'invention présenté aux figures 4 et 5, les moyens de centrage 15 coopèrent avec l'intérieur de l'extrémité amont 10 (voir notamment la figure 4).  In a second embodiment of the invention shown in FIGS. 4 and 5, the centering means 15 cooperate with the inside of the upstream end 10 (see in particular FIG. 4).
A cet effet, comme on peut le voir à la figure 5 représentant l'organe formant labyrinthe 13 seul, les moyens de centrage 15 comportent des butées de centrage 16 destinées à être réparties circonférentiellement à l'intérieur de l'extrémité amont 10.  For this purpose, as can be seen in FIG. 5 representing the labyrinth member 13 alone, the centering means 15 comprise centering stops 16 intended to be distributed circumferentially inside the upstream end 10.
Dans le mode de réalisation particulier représenté sur la figure 5, les butées de centrage 16 forment une étoile à quatre branches centrée sur l'axe de l'organe formant labyrinthe 13.  In the particular embodiment shown in FIG. 5, the centering stops 16 form a four-pointed star centered on the axis of the labyrinth member 13.
Dans d'autres variantes non représentées, les butées de centrage 16 forment une étoile comprenant un nombre différents de branches, par exemple trois, cinq ou six.  In other variants not shown, the centering stops 16 form a star comprising a different number of branches, for example three, five or six.
On notera toutefois que les butées de centrage ne sont pas nécessairement réparties uniformément autour de l'axe de symétrie de l'organe formant labyrinthe ni centrées sur l'axe de l'organe formant labyrinthe.  Note however that the centering stops are not necessarily evenly distributed around the axis of symmetry of the labyrinth member nor centered on the axis of the labyrinth member.
D'une manière générale, l'invention n'est pas limitée aux modes de réalisation présentés et d'autres modes de réalisation apparaîtront clairement à l'homme du métier.  In general, the invention is not limited to the embodiments shown and other embodiments will become apparent to those skilled in the art.

Claims

REVENDICATIONS
1 . Pompe (2) destinée à relier l'intérieur et l'extérieur d'un réservoir de produit pharmaceutique comportant une extrémité amont (10) de passage de produit destinée à s'étendre dans le réservoir et à être en communication fluidique avec le réservoir et, en en aval de l'extrémité amont (10), un clapet anti-retour (11 ) évoluant entre des configurations d'obturation et de passage de produit, caractérisée en ce que l'extrémité amont (10) est prolongée en amont par un organe (13) formant un passage de produit en labyrinthe, dit organe formant labyrinthe. 1. A pump (2) for connecting the interior and exterior of a pharmaceutical reservoir having an upstream product passage end (10) for extending into the reservoir and being in fluid communication with the reservoir and , downstream of the upstream end (10), a non-return valve (11) moving between closure and product passage configurations, characterized in that the upstream end (10) is extended upstream by a member (13) forming a labyrinth product passage, said labyrinth forming member.
2. Pompe (2) selon la revendication 1 , dans laquelle l'extrémité amont (10) est de forme générale tubulaire.  2. Pump (2) according to claim 1, wherein the upstream end (10) is of generally tubular shape.
3. Pompe (2) selon l'une quelconque des revendications précédentes, dans laquelle l'organe formant labyrinthe (13) a une forme générale de cloche.  3. Pump (2) according to any one of the preceding claims, wherein the labyrinth member (13) has a general bell shape.
4. Pompe (2) selon l'une quelconque des revendications précédentes, dans laquelle l'organe formant labyrinthe (13) est muni de moyens de centrage (15) par rapport à l'extrémité amont (10).  4. Pump (2) according to any one of the preceding claims, wherein the labyrinth member (13) is provided with centering means (15) relative to the upstream end (10).
5. Pompe (2) selon la revendication 4, dans laquelle les moyens de centrage (15) coopèrent avec l'intérieur de l'extrémité amont (10).  5. Pump (2) according to claim 4, wherein the centering means (15) cooperate with the interior of the upstream end (10).
6. Pompe (2) selon la revendication 5, dans laquelle les moyens de centrage (15) comportent des butées de centrage (16) réparties circonférentiellement à l'intérieur de l'extrémité amont (10).  6. Pump (2) according to claim 5, wherein the centering means (15) comprise centering stops (16) distributed circumferentially inside the upstream end (10).
7. Pompe (2) selon la revendication 4, dans laquelle les moyens de centrage (15) coopèrent avec l'extérieur de l'extrémité amont (10).  7. Pump (2) according to claim 4, wherein the centering means (15) cooperate with the outside of the upstream end (10).
8. Pompe (2) selon la revendication 7, dans laquelle les moyens de centrage (15) comportent des butées de centrage (16) réparties circonférentiellement autour de l'extrémité amont (10).  8. Pump (2) according to claim 7, wherein the centering means (15) comprise centering stops (16) distributed circumferentially around the upstream end (10).
9. Ensemble de pompe (2) et de poche souple formant réservoir de produit pharmaceutique, caractérisé en ce que la pompe (2) est selon l'une quelconque des revendications précédentes.  9. Pump assembly (2) and flexible pouch forming a pharmaceutical reservoir, characterized in that the pump (2) is according to any one of the preceding claims.
10. Dispositif de distribution de produit pharmaceutique comprenant une pompe 10. Pharmaceutical dispensing device comprising a pump
(2), caractérisé en ce que cette pompe (2) est selon l'une quelconque des revendications 1 à 8. (2), characterized in that this pump (2) is according to any one of claims 1 to 8.
EP16734413.4A 2015-05-29 2016-05-26 Improved pump connecting the inside and the outside of a product vessel Pending EP3302820A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1554901A FR3036632B1 (en) 2015-05-29 2015-05-29 PUMP CONNECTING THE INTERIOR AND OUTSIDE OF AN IMPROVED PRODUCT TANK
PCT/FR2016/051236 WO2016193575A1 (en) 2015-05-29 2016-05-26 Improved pump connecting the inside and the outside of a product vessel

Publications (1)

Publication Number Publication Date
EP3302820A1 true EP3302820A1 (en) 2018-04-11

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EP16734413.4A Pending EP3302820A1 (en) 2015-05-29 2016-05-26 Improved pump connecting the inside and the outside of a product vessel

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US (1) US10393110B2 (en)
EP (1) EP3302820A1 (en)
FR (1) FR3036632B1 (en)
WO (1) WO2016193575A1 (en)

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Publication number Priority date Publication date Assignee Title
CN109550142A (en) * 2019-01-22 2019-04-02 川北医学院附属医院 A kind of chronic wound nursing feeding device

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
EP0016839B1 (en) * 1978-06-07 1982-10-20 Yoshino Kogyosho Co., Ltd. Sprayer used in both standing and over turning attitudes
DE3521580A1 (en) * 1985-02-21 1986-08-21 Bayer Ag, 5090 Leverkusen OUTPUT DEVICE FOR FLOWABLE MEDIA
US5397059A (en) * 1992-03-20 1995-03-14 L'oreal Dispenser equipped with a liquid pump and a pressurized gas/liquid nozzle
GB9519346D0 (en) * 1995-09-22 1995-11-22 English Glass Company The Limi Dispensing systems
FR2740114B1 (en) * 1995-10-19 1998-01-02 Innovation Rech Plastique Sa PRODUCT PACKAGING DEVICE WITH SUPPORT RING OF A MANUAL PUMP FOR DISPENSING IN UNIT DOSES
US5979712A (en) * 1997-10-24 1999-11-09 Monturas, S.A. Upright/inverted sprayer
US6257455B1 (en) * 1999-12-17 2001-07-10 Owens-Illinois Closure Inc. Pump dispenser having passive venting means
JP3563014B2 (en) * 2000-06-26 2004-09-08 株式会社トップ Discharge container
DE10231751B4 (en) * 2002-07-13 2004-07-29 Aero Pump GmbH, Zerstäuberpumpen Suction-pressure pump for ejecting a product from a container
FR2849477B1 (en) 2002-12-26 2006-05-19 Rexam Dispensing Sys METHOD FOR INTEGRATING A BALLOVER RETURN VALVE IN A PUMP BODY
FR2911853B1 (en) * 2007-01-30 2009-04-10 Rexam Dispensing Smt Soc Par A VIAL COMPRISING A COLLAR ASSEMBLED ON A BODY

Also Published As

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FR3036632A1 (en) 2016-12-02
US10393110B2 (en) 2019-08-27
WO2016193575A1 (en) 2016-12-08
US20180142683A1 (en) 2018-05-24
FR3036632B1 (en) 2017-05-26

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