EP3253760A4 - Procédé de synthèse de baricitinib et d'un intermédiaire de celui-ci - Google Patents
Procédé de synthèse de baricitinib et d'un intermédiaire de celui-ci Download PDFInfo
- Publication number
- EP3253760A4 EP3253760A4 EP16746200.1A EP16746200A EP3253760A4 EP 3253760 A4 EP3253760 A4 EP 3253760A4 EP 16746200 A EP16746200 A EP 16746200A EP 3253760 A4 EP3253760 A4 EP 3253760A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- baricitinib
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- XUZMWHLSFXCVMG-UHFFFAOYSA-N baricitinib Chemical compound C1N(S(=O)(=O)CC)CC1(CC#N)N1N=CC(C=2C=3C=CNC=3N=CN=2)=C1 XUZMWHLSFXCVMG-UHFFFAOYSA-N 0.000 title 1
- 229950000971 baricitinib Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN289MU2016 | 2015-02-02 | ||
PCT/IB2016/050529 WO2016125080A2 (fr) | 2015-02-02 | 2016-02-02 | Procédé de synthèse de baricitinib et d'un intermédiaire de celui-ci |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3253760A2 EP3253760A2 (fr) | 2017-12-13 |
EP3253760A4 true EP3253760A4 (fr) | 2018-06-20 |
Family
ID=60239701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16746200.1A Withdrawn EP3253760A4 (fr) | 2015-02-02 | 2016-02-02 | Procédé de synthèse de baricitinib et d'un intermédiaire de celui-ci |
Country Status (1)
Country | Link |
---|---|
EP (1) | EP3253760A4 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020072870A1 (fr) | 2018-10-05 | 2020-04-09 | Johnson Matthey Public Limited Company | Formes co-cristallines du baricitinib |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8158616B2 (en) * | 2008-03-11 | 2012-04-17 | Incyte Corporation | Azetidine and cyclobutane derivatives as JAK inhibitors |
-
2016
- 2016-02-02 EP EP16746200.1A patent/EP3253760A4/fr not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8158616B2 (en) * | 2008-03-11 | 2012-04-17 | Incyte Corporation | Azetidine and cyclobutane derivatives as JAK inhibitors |
Also Published As
Publication number | Publication date |
---|---|
EP3253760A2 (fr) | 2017-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20170904 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20180523 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07D 487/04 20060101AFI20180516BHEP Ipc: A61K 31/4353 20060101ALI20180516BHEP Ipc: A61K 31/397 20060101ALI20180516BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20190314 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20190525 |