EP3253760A4 - Verfahren zur herstellung von baricitinib und zwischenprodukten davon - Google Patents

Verfahren zur herstellung von baricitinib und zwischenprodukten davon Download PDF

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Publication number
EP3253760A4
EP3253760A4 EP16746200.1A EP16746200A EP3253760A4 EP 3253760 A4 EP3253760 A4 EP 3253760A4 EP 16746200 A EP16746200 A EP 16746200A EP 3253760 A4 EP3253760 A4 EP 3253760A4
Authority
EP
European Patent Office
Prior art keywords
baricitinib
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16746200.1A
Other languages
English (en)
French (fr)
Other versions
EP3253760A2 (de
Inventor
Md Abul Kalam AZAD
Gyanendra Pandey
Kaptan Singh
Mohan Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Ltd
Original Assignee
Sun Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Industries Ltd filed Critical Sun Pharmaceutical Industries Ltd
Priority claimed from PCT/IB2016/050529 external-priority patent/WO2016125080A2/en
Publication of EP3253760A2 publication Critical patent/EP3253760A2/de
Publication of EP3253760A4 publication Critical patent/EP3253760A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EP16746200.1A 2015-02-02 2016-02-02 Verfahren zur herstellung von baricitinib und zwischenprodukten davon Withdrawn EP3253760A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN289MU2016 2015-02-02
PCT/IB2016/050529 WO2016125080A2 (en) 2015-02-02 2016-02-02 Process for the preparation of baricitinib and an intermediate thereof

Publications (2)

Publication Number Publication Date
EP3253760A2 EP3253760A2 (de) 2017-12-13
EP3253760A4 true EP3253760A4 (de) 2018-06-20

Family

ID=60239701

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16746200.1A Withdrawn EP3253760A4 (de) 2015-02-02 2016-02-02 Verfahren zur herstellung von baricitinib und zwischenprodukten davon

Country Status (1)

Country Link
EP (1) EP3253760A4 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020072870A1 (en) 2018-10-05 2020-04-09 Johnson Matthey Public Limited Company Co-crystal forms of baricitinib

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158616B2 (en) * 2008-03-11 2012-04-17 Incyte Corporation Azetidine and cyclobutane derivatives as JAK inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158616B2 (en) * 2008-03-11 2012-04-17 Incyte Corporation Azetidine and cyclobutane derivatives as JAK inhibitors

Also Published As

Publication number Publication date
EP3253760A2 (de) 2017-12-13

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