EP3244709A1 - Gradient corrector for cyclotron - Google Patents

Gradient corrector for cyclotron Download PDF

Info

Publication number
EP3244709A1
EP3244709A1 EP16169494.8A EP16169494A EP3244709A1 EP 3244709 A1 EP3244709 A1 EP 3244709A1 EP 16169494 A EP16169494 A EP 16169494A EP 3244709 A1 EP3244709 A1 EP 3244709A1
Authority
EP
European Patent Office
Prior art keywords
hill
recess
edge
peripheral edge
central axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP16169494.8A
Other languages
German (de)
French (fr)
Other versions
EP3244709B1 (en
Inventor
Willem Kleeven
Szymon Zaremba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ion Beam Applications SA
Original Assignee
Ion Beam Applications SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ion Beam Applications SA filed Critical Ion Beam Applications SA
Priority to EP16169494.8A priority Critical patent/EP3244709B1/en
Priority to CA2965016A priority patent/CA2965016C/en
Priority to CN201720510663.7U priority patent/CN207201060U/en
Priority to CN201710320606.7A priority patent/CN107371316B/en
Priority to JP2017093672A priority patent/JP6446089B2/en
Priority to US15/594,534 priority patent/US10278277B2/en
Priority to US15/594,525 priority patent/US10064264B2/en
Priority to US15/594,527 priority patent/US9961757B2/en
Priority to US15/594,538 priority patent/US9907153B2/en
Publication of EP3244709A1 publication Critical patent/EP3244709A1/en
Application granted granted Critical
Publication of EP3244709B1 publication Critical patent/EP3244709B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H13/00Magnetic resonance accelerators; Cyclotrons
    • H05H13/005Cyclotrons
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H7/00Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
    • H05H7/04Magnet systems, e.g. undulators, wigglers; Energisation thereof
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H7/00Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
    • H05H7/04Magnet systems, e.g. undulators, wigglers; Energisation thereof
    • H05H2007/043Magnet systems, e.g. undulators, wigglers; Energisation thereof for beam focusing

Definitions

  • the present invention concerns cyclotrons.
  • it concerns isochronous sector-focused cyclotrons having enhanced focusing of an extracted beam of energized charged particles.
  • a cyclotron is a type of circular particle accelerator in which negatively or positively charged particles are accelerated outwards from the centre of the cyclotron along a spiral path up to energies of several MeV.
  • cyclotron is used in the following to refer to isochronous cyclotrons. Cyclotrons are used in various fields, for example in nuclear physics, in medical treatment such as proton-therapy, or in radio-pharmacy.
  • cyclotrons can be used for producing short-lived positron-emitting isotopes suitable for PET imaging (positron emitting tomography) or for producing gamma-emitting isotopes, for example, Tc99m, for SPECT imaging (single photon emission computed tomography).
  • a cyclotron comprises several elements including an injection system, a radiofrequency (RF) accelerating system for accelerating the charged particles, a magnetic system for guiding the accelerated particles along a precise path, an extraction system for collecting the thus accelerated particles, and a vacuum system for creating and maintaining a vacuum in the cyclotron.
  • RF radiofrequency
  • a particle beam constituted of charged ions is introduced into a gap at or near the center of the cyclotron by the injection system with a relatively low initial velocity. As illustrated in Fig. 3 , this particle beam is sequentially and repetitively accelerated by the RF accelerating system and guided outwards along a spiral path comprised within the gap by the magnetic field generated by the magnetic system.
  • the particle beam reaches its target energy, it can be extracted from the cyclotron by the extraction system provided at a point of extraction, PE.
  • This extraction system can comprise, for example, a stripper consisting of a thin sheet of graphite. For example, H - ions passing through the stripper lose two electrons and become positive. Consequently, the curvature of their path in the magnetic field changes its sign, and the particle beam is thus led out of the cyclotron towards a target.
  • Other extracting systems exist which are well known to the persons skilled in the art.
  • the magnetic system generates a magnetic field that guides and focuses the beam of charged particles along the spiral path until it is accelerated to its target energy.
  • particles charged particles
  • ions used indifferently as synonyms.
  • the magnetic field is generated in the gap defined between two magnet poles by two solenoid coils, 14, wound around these poles. Magnet poles of cyclotrons are often divided into alternating hill sectors and valley sectors distributed around a central axis. The gap between two magnet poles is smaller at the hill sectors and the larger at the valley sectors. A strong magnetic field is thus created in the hill gap portions within the hill sectors and a weaker magnetic field is created in the valley gap portions within the valley sectors.
  • a hill sector has a geometry of a circular sector similar to a slice of cake with a first and second lateral surfaces extending substantially radially towards the central axis, a generally curved peripheral surface, a central surface adjacent to the central axis, and an upper surface defining one side of a hill gap portion.
  • the upper surface is delimited by a first and second lateral edges, a peripheral edge, and a central edge.
  • a particle beam has a cross sectional area.
  • An objective of cyclotrons is to produce charged particle beams having a given energy which are as much focused as possible (i.e. having a small cross sectional area)
  • the variations of the magnetic field created by the succession of hill sectors and valley sectors contributes to the focusing of the beam in a similar way as a light beam can be focused by lenses.
  • the particle beam crosses boundary regions where the magnetic field loses its homogeneity, which is detrimental to the focusing of the particle beam.
  • protruding gradient correctors has, however, several drawbacks.
  • the volume of the vacuum chamber hosting the magnet poles must be increased accordingly, thus requiring more energy and time to pump the gases from the vacuum chamber.
  • the overall weight of the cyclotron is increased because of, on the one hand, the weight of the gradient correctors themselves and, on the other hand, the increased overall size of the outer walls of the vacuum chamber and, consequently, the size of the flux return yoke; both contributing to a substantial increase of the cyclotron weight.
  • the position of the protruding gradient correctors is essential; small deviations ofposition may yield large variations of the magnetic field.
  • Gradient correctors must be fixed manually by a skilled artisan at precisely the same position of the peripheral surface of all the hill sectors. This is of course, a critical and expensive operation. Fourth, these protruding gradient correctors have the effect of deviating the magnetic field outwards, which pulls outwards the path of the particle beam towards the peripheral edge of a hill gap portion between a pair of opposed hill sectors where the magnetic field loses its homogeneity. This shift also leads to a loss of useful magnetic field and thus requires an increase of the coil current in order to compensate this loss. It is therefore more difficult and expensive to control the properties of the extracted particle beam.
  • the present invention concerns a magnet pole for a cyclotron comprising at least 3 hill sectors and a same number of valley sectors comprising a bottom surface, said hill sectors and valley sectors being alternatively distributed around a central axis, Z, each hill sector comprising:
  • the recess is generally wedge shaped with a first and second converging lines (preferably straight lines) extending away from the upper peripheral edge, with a converging angle, ⁇ , preferably comprised between 70° and 130°, more preferably between 80°and 110°, most preferably 90° ⁇ 5°.
  • the recess has a converging portion, away from the upper peripheral edge, said converging portion having one of the following geometry:
  • the upper peripheral edge has an azimuthal length, Ah, and wherein the concave portion extends between 3% and 30% of the azimuthal length of the upper peripheral edge, preferably, between 5% and 20%, more preferably, between 8% and 15%.
  • the recess is separated from the first and second upper lateral edges.
  • the recess is adjacent to the first upper lateral edge.
  • the recess can extend over a portion of the peripheral surface.
  • the portion of the peripheral surface correspond to a fraction, ⁇ , of the height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and the lower peripheral line, wherein the fraction, ⁇ , is comprised between 25% and 75%, preferably between 40% and 60%, most preferably between 45% and 55%.
  • the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
  • the upper peripheral edge is an arc of circle which centre is offset with respect to the central axis, and which radius is not more than 85% of a distance from the central axis to a midpoint of the upper peripheral edge, which is equidistant to the first and second upper distal ends.
  • the invention also relates to a cyclotron for accelerating a particle beam over a given path comprised within a gap, said cyclotron comprising first and second magnet poles such as described above, wherein the first and second magnet poles are positioned symmetrically with respect to a median plane normal to the central axes of first and second magnet pole forming said gap in between, with hill gap portion being formed between two opposite hill sectors and valley gap portions being formed between two opposite valley sectors.
  • the recess of a cyclotron has a first and a second recess distal points, said first and second recess distal points being separated from one another by a distance L10, and wherein the hill gap portion between a pair of hill sectors of the first and second magnet poles has an average height, Gh, and wherein the ratio Gh / L10 is comprised between 5 and 100 %, preferably between 10 and 50 %, more preferably, 20 and 33 %.
  • the cyclotron can also comprise a point of extraction, located in a hill gap portion between two opposite upper surfaces of hill sectors of the first and second magnet poles, wherein the given path of the particle beam is an outward spiral path cycling about the central axis until said first point of extraction whence the particle beam can be driven out of the cyclotron with a given energy along an extraction path, and wherein the recess is located downstream from said point of extraction wherein downstream is defined with respect to the direction of the particle beam, such that the extraction path crosses on line of the recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  • the cyclotron further comprises a second point of extraction in a hill sector defining a second extraction path, and comprising a second recess located downstream from the second point of extraction, such that the second extraction path crosses one line of the second recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  • the present invention concerns isochronous sector-focused cyclotrons, hereafter referred to as cyclotron of the type discussed in the technical background section supra.
  • a cyclotron according to the present invention accelerates charged particles outwards from a central area of the cyclotron along a spiral path 12 until they are extracted at energies of several MeV.
  • the charged particles thus extracted can be protons, H + , or deuteron, D + .
  • the energy reached by the extracted particles is comprised between 5 and 30 MeV, more preferably between 15 and 21 MeV, most preferably 18 MeV.
  • Cyclotrons of such energies are used, for example, for producing short-lived positron-emitting isotopes suitable for use in PET imaging (positron emitting tomography) or for producing gamma-emitting isotopes, for example, Tc99m, for SPECT imaging (single photon emission computed tomography).
  • a cyclotron 1 comprises two base plates 5 and flux return yokes 6 which, together, form a yoke.
  • the flux return yokes form the outer walls of the cyclotron and control the magnetic field outside of the coils 14 by containing it within the cyclotron.
  • It further comprises first and second magnet poles 2 located in a vacuum chamber, facing each other symmetrically with respect to a median plane MP normal to a central axis, Z, and separated from one another by a gap 7.
  • the yoke and the magnet poles are all made of a magnetic material, preferably a low carbon steel and form a part of the magnetic system.
  • the magnetic system is completed by a first and second coils 14 made of electrically conductive wires wounded around the first and second magnet poles and fitting within an annular space defined between the magnet poles and the flux return yokes.
  • Each hill sector 3 represented in Fig. 1(b) as light shaded areas, has an upper surface 3U extending over a hill azimuthal angle, ⁇ h .
  • Each of the first and second magnet poles 2 further comprises the same number, N, of valley sectors 4, represented in Fig. 1(b) as dark shaded areas, distributed radially around the central axis Z.
  • the hill sectors 3 and valley sectors 4 of the first magnet pole 2 face the opposite hill sectors 3 and valley sectors 4 , respectively, of the second magnet pole 2.
  • the path 12 followed by the particle beam illustrated in Fig. 3 is comprised within the gap 7 separating the first and second magnet poles.
  • the gap 7 between the first and second magnet poles thus comprises hill gap portions 7h defined between the upper surfaces 3U of two opposite hill sectors 3 and valley gap portions 7v defined between the bottom surfaces 4B of two opposite valley sectors 4.
  • the hill gap portions 7h have an average gap height, Gh, defined as the average height of the hill gap portions over the areas of two opposite upper surfaces 3U .
  • Average hill and valley gap heights are measured as the average of the gap heights over the whole upper surface and lower surface of a hill sector and a valley sector, respectively.
  • the average of the valley gap height ignores any opening on the bottom surfaces.
  • the upper surface 3U is defined by (see Fig. 2 ):
  • a hill sector 3 further comprises (see Fig. 2 ):
  • the average height of a hill, Hh , sector is the average distance measured parallel to the central axis between lower and upper lateral edges.
  • An end of an edge is defined as one of the two extremities bounding a segment defining the edge.
  • a proximal end is the end of an edge located closest from the central axis, Z.
  • a distal end is the end of an edge located furthest from the central axis, Z.
  • An end can be a corner point which is defined as a point where two or more lines meet.
  • a corner point can also be defined as a point where the tangent of a curve changes sign or presents a discontinuity.
  • An edge is a line segment where two surfaces meet.
  • An edge is bounded by two ends, as defined supra, and defines one side of each of the two meeting surfaces.
  • R radius of curvature
  • the edge is defined as the geometric line intersecting the two surfaces extrapolated so as to intersect each other with and infinite curvature (1/R).
  • An upper edge is an edge intersecting the upper surface 3U of a hill sector, and a lower edge is an edge intersecting the bottom surface 4B of a valley sector.
  • a peripheral edge is defined as the edge of a surface comprising the point located the furthest from the central axis, Z. If the furthest point is a corner point shared by two edges, the peripheral edge is also the edge of a surface which average distance to the central axis, Z, is the largest.
  • the upper peripheral edge is the edge of the upper surface comprising the point located the furthest to the central axis. If a hill sector is compared to a slice of tart, the peripheral edge would be the peripheral crust of the tart.
  • a central edge is defined as the edge of a surface comprising the point located the closest to the central axis, Z.
  • the upper central edge is the edge of the upper surface comprising the point located the closest to the central axis, Z.
  • a lateral edge is defined as the edge joining a central edge at a proximal end to a peripheral edge at a distal end.
  • the proximal end of a lateral edge is therefore the end of said lateral edge intersecting a central edge, and the distal end of said lateral edge is the end of said lateral edge intersecting a peripheral edge.
  • the upper / lower central edge may have different geometries.
  • the most common geometry is a concave line (or concave curve), often circular, of finite length ( ⁇ 0), with respect to the central axis, which is bounded by a first and second upper / lower proximal ends, separated from one another.
  • This configuration is useful as it clears space for the introduction into the gap of the particle beam and other elements.
  • the first and second proximal central ends are merged into a single proximal central point, forming a summit of the upper surface 3U , which comprises three edges only, the central edge having a zero-length.
  • the transition from the first to the second lateral edges can be a curve convex with respect to the central axis, Z, leading to a smooth transition devoid of any corner point.
  • the central edge is also reduced to a single point defined as the point wherein the tangent changes sign.
  • a hill sector does not extend all the way to the central axis, the central area directly surrounding the central axis is cleared to allow insertion of the particle beam or installation of other elements.
  • the first and second lateral surfaces 3L are preferably chamfered forming a chamfer 3ec at the first and second upper lateral edges, respectively.
  • a chamfer is defined as an intermediate surface between two surfaces obtained by cutting off the edge which would have been formed by the two surfaces absent a chamfer.
  • a chamfer reduces the angle formed at an edge between two surfaces.
  • Chamfers are often used in mechanics for reducing stress concentrations. In cyclotrons, however, a chamfered lateral surface at the level of the upper surface of a hill sector enhances the focusing of the particle beam as it reaches a hill gap portion 7h.
  • the peripheral surface 3P of a hill sector can also form a chamfer at the upper peripheral edge, which improves the homogeneity of the magnetic field near the peripheral edge.
  • the hill sectors 3 and valley sectors 4 must be distributed about the central axis with a symmetry of N.
  • the first and second magnet poles 2 are positioned with their respective upper surfaces 3U facing each other and symmetrically with respect to the median plane MP normal to the respective central axes Z of the first and second magnet poles 2 , which are coaxial.
  • the shape of the hill sectors is often wedge shaped like a slice of tart (often, as discussed supra, with a missing tip) with the first and second lateral surfaces 3L converging from the peripheral surface towards the central axis Z (usually without reaching it).
  • the hill azimuthal angle, ⁇ h corresponds to the converging angle, measured at the level of the intersection point of the (extrapolated) upper lateral edges of the lateral surfaces at, or adjacent to, the central axis Z .
  • the hill azimuthal angle, ⁇ h is preferably comprised between 360°/2N ⁇ 10°, more preferably between 360° / 2N ⁇ 5°, most preferably between 360° / 2N ⁇ 2°.
  • the valley azimuthal angle ⁇ v measured at the level of the central axis Z is preferably comprised between 360° / 2N ⁇ 10°, more preferably between 360° / 2N ⁇ 5°, most preferably between 360° / 2N ⁇ 2°.
  • the valley azimuthal angle ⁇ v can be equal to the hill azimuthal angle, ⁇ h .
  • the largest distance, Lh, between the central axis and a peripheral edge is preferably comprised between 200 and 2000 mm, more preferably between 400 and 1000 mm, most preferably between 500 and 800 mm.
  • the longest distance, Lh is usually less than 750 mm, and can be of the order of 500 to 750 mm, typically 520 to 550 mm.
  • the two magnet poles 2 and solenoid coils 14 wound around each magnet pole,_form an (electro-)magnet which generates a magnetic field in the gap 7 between the magnetic poles that guides and focuses the beam of charged particles ( particle beam) along a spiral path 12 illustrated in Fig. 3 , starting from the central area (around the central axis, Z) of the cyclotron, until it reaches a target energy, for example of 18 MeV, whence it is extracted.
  • the magnet poles are divided into alternating hill sectors and valley sectors distributed around the central axis, Z. A strong magnetic field is thus created in the hill gap portions 7h of average height Gh within the hill sectors and a weaker magnetic field is created in the valley gap portions 7v of average height Gv > Gh, within the valley sectors thus creating vertical focusing of the particle beam.
  • a particle beam When a particle beam is introduced into a cyclotron, it is accelerated by an electric field created between high voltage electrodes called dees (not shown), and ground voltage electrodes attached to the lateral edges of the poles, positioned in the valley sectors, where the magnetic field is weaker.
  • dees high voltage electrodes
  • ground voltage electrodes attached to the lateral edges of the poles, positioned in the valley sectors, where the magnetic field is weaker.
  • energetic protons H +
  • H + can be extracted by driving a beam of accelerated H - ions through a stripper consisting of a thin foil sheet of graphite.
  • a H - ion passing through the stripper loses two electrons to become a positive, H + .
  • the curvature of its path in the magnetic field changes sign, and the particle beam is thus led out of the cyclotron towards a target (not shown).
  • Other extracting systems are known by the persons skilled in the art and the type and details of the extraction system used is not essential to the present invention.
  • a point of extraction is located in a hill gap portion 7h.
  • a cyclotron can comprise several points of extraction in a same hill portion.
  • more than one hill sector comprises an extraction point.
  • all N hill sectors comprise the same number of points of extraction.
  • the points of extraction can be used individually (one only at a time) or simultaneously (several at a time).
  • Such hill sector of cyclotron according to the present invention comprises a first and second lateral surfaces 3L , a peripheral surface 3P and an upper surface 3U such as defined above.
  • the upper peripheral edge 3up of the upper surface of at least one hill sector comprises a convex portion adjacent to a concave portion with respect to the central axis defining a recess extending partially over a portion of the peripheral surface of the corresponding hill sector.
  • the upper peripheral edge 3up of the upper surface of at least one hill sector comprises 2 convex portions separated by a concave portion.
  • each hill sector preferably, comprises a concave portion 3upc with respect to the central axis defining a recess 10 extending partially over the peripheral surface of the corresponding hill sector between two convex portions.
  • concave means curving in or hollowed inward.
  • the concave portion with respect to the central axis of an edge is a portion of the edge curving towards the central axis. This term is opposed to the term “convex” that means curving out of or extending outward from the central axis.
  • a hill sector comprises at least one recess separated from the lateral edges.
  • Protruding gradient correctors have several drawbacks:
  • recessed gradient correctors instead of protruding gradient correctors has several advantages.
  • the position of the recesses can be precisely manufactured and positioned by numerically controlled machining allowing the optimization of the angle at which the particle beam crosses the peripheral edge of the hill sector.
  • Fig. 4 shows an example of the lines of the magnetic field deviated by the recessing gradient corrector ( Fig. 5(a) ) and without any gradient corrector ( Fig. 5(b) ). It is therefore easier and more predictable to control the properties of the extracted particle beam, and particularly the focusing thereof. This deviation towards the acceleration area also allows the power fed to the coils to be decreased.
  • the upper peripheral edge 3up comprises a first and a second recess distal points 10rdp , defining the boundaries of a recess, and which are defined as the points where the tangent of the upper peripheral edge changes sign or presents a discontinuity.
  • the first and second recess distal points are separated from one another by a distance L10.
  • the recess also comprises a recess proximal point 10rpp defined as the point of the recess located closest to the central axis, Z.
  • the first and second recess distal points 10rdp join the recess proximal point 10rpp by a first and second recess converging edges 10rc .
  • the recess depth, H10 is defined as the height of the triangle formed by the first and second recess distal points 10rdp and the recess proximal point 10rpp , and passing by the recess proximal point 10rpp .
  • the depth of the recess, H10 is comprised between 3% and 30%, preferably, between 5% and 20%, more preferably, between 8% and 15% of the azimuthal length, Ah, of the upper peripheral edge.
  • the ratio of the recess depth, H10 , to the largest distance, Lh , between the central axis and a peripheral edge of a hill sector, H10 / Lh is comprised between between 2% and 20%, preferably, between 4% and 15%, more preferably, between 6% and 10%.
  • the upper peripheral edge 3up has an azimuthal length, Ah, measured between the first and second upper distal ends 3ude .
  • the first recess converging edge 10r1 joining the first recess distal point to the recess proximal point has a length L101 and the second recess converging edge 10r2 joining the second recess distal point to the recess proximal point has a length L102.
  • the lengths L101 and L102 of the first and second recess converging edges are comprised between 5 and 30% of the azimuthal length, Ah, of the upper peripheral edge.
  • the distance L10 between first and second recess distal points ranges between 5% and 50%, more preferably, between 10% and 30%, most preferably, between 15% and 20% of the azimuthal length, Ah, of the upper peripheral edge.
  • the recess also extends over a portion of the peripheral surface 3P from the upper peripheral edge 3up towards the lower peripheral line 31p.
  • the recess thus extends over the peripheral surface over a fraction, ⁇ , of a height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and lower peripheral line.
  • the fraction, ⁇ is preferably, comprised between 25% and 100%, preferably between 40% and 75%, most preferably between 45% and 55%.
  • the concave portion of the upper peripheral edge can have any of the following geometries open between the first and second recess distal points: (a) a rectangle, (b) a trapeze, (c) a triangle having straight edges or curved (inwards or outwards) edges, (d) an arc of circle, (e) two arcs of circle, (f) a parabola, (g) a square, (h) a parallelogram, (i) a polygon, (j) a smooth curve. Basically, any geometry determined by numerical analysis can be implemented.
  • the small base can comprise the recess proximal point 10rpp
  • the large base can be defined by the first and second recess distal points 10rdp
  • the small base can be defined by the first and second recess distal points 10rdp
  • the large base can comprise the recess proximal point 10rpp
  • a triangle can be scalene, isosceles or equilateral. It can also be right, with the right angle formed at the recess proximal point 10rpp .
  • two (or more) arc of circle they can be curved inwards ((e) right) or outwards ((e) left).
  • the concave portion is preferably designed such that one edge thereof intersects the extraction path of a particle beam with an angle of 80-100°, preferably 85-95°, substantially 90°.
  • a recess 10 extends over a portion of the peripheral surface parallel to the central axis. Alternatively, it can extend downwards from the upper surface with an angle with the central axis, Z.
  • the distance L10 and/or the height H10 can increase or decrease independently of one another or simultaneously along the height of the peripheral surface.
  • the area of the cross-section of the recess normal to the central axis, Z can thus decrease or increase with the distance from the upper surface.
  • the geometry and the area of the cross-section of the recess can change over the peripheral surface.
  • the height of the recess can also vary over the peripheral surface.
  • Fig. 7 illustrates some examples of geometries of recesses.
  • the recess can have a shape of: (a) a prism extending from the upper surface parallel to the central axis, (b) a prism extending from the peripheral surface normal to the central axis, (c) a (portion of) pyramid, or more complex volumes extending over the peripheral surface.
  • the recess is generally wedge shaped with the first and second recess converging edges being straight (or slightly curved inwards or outwards) lines.
  • the tip of the wedge corresponds to the recess proximal point and points at the general direction of the central axis.
  • the converging angle, ⁇ , at the tip of the wedge is preferably comprised between 70° and 130°, more preferably between 80° and 110°, most preferably 90° ⁇ 5°.
  • the expressions "inwards” and “outwards” used herein are to be understood as “towards” or “away from” the central axis, respectively.
  • the converging portion of the wedge-shaped recess can have one of the following geometries:
  • the present invention also concerns a cyclotron comprising magnet poles as defined supra.
  • a cyclotron accelerates a particle beam over a given path until a first point of extraction whence the particle beam is driven out of the cyclotron with a given energy.
  • the hill gap portion between a pair of hill of the first and second magnet poles of a cyclotron has an average height, Gh.
  • the ratio of the distance L10 between first and second recess distal points 10rdp to the height of hill gap portion Gh is comprised between 1 and 20, preferably between 2 and 10, more preferably, 3 and 5.
  • the distance L10 can be of the order of 10-100 mm, yielding a ratio L10/Gh which can be comprised between 1-5, preferably between 3 and 3.5, i.e. Gh / L10 ⁇ 1.
  • a point of extraction is located within a hill gap portion adjacent to the peripheral edges of a pair of opposed hill sectors.
  • a recess is located downstream from said first point of extraction wherein downstream is defined with respect to the direction of the particle beam.
  • the recess 10 is precisely machined with respect to the point of extraction and to the extraction path such that the particle beam intersects the first converging recess edge 10r1 with an angle of 90° ⁇ 15°.
  • the particle beam thus leaves the hill gap portion substantially normal to the magnetic field, which improves the focusing of the extracted particle beam.
  • the position and the geometry of the recess are determined by numerical computation and/or testing.
  • the cyclotron may further comprise a second point of extraction, PE2, located downstream from the first point of extraction, PE1, and within the same hill gap portion of the same pair of opposed hill sectors.
  • the particle beam can be driven out of the cyclotron at said second point of extraction with the same energy as at said first point of extraction.
  • the hill sector comprising the two extraction points also comprises two recesses, each located downstream from a corresponding point of extraction.
  • Fig. 9 shows an example of a preferred embodiment of a magnet pole for a cyclotron according to the present invention.
  • the upper peripheral edge 3up is bounded by a first and a second upper distal ends
  • the upper peripheral edge of a hill sector comprises an arc of circle 3ac which centre is offset with respect to the central axis, and which radius, Rh, is not more than 85 % of a distance, Lh, from the central axis to a midpoint of the upper peripheral edge, which is equidistant to the first and second upper distal ends (Rh / Lh ⁇ 85%).
  • the ratio Rh / Lh of the radius, Rh , to the distance Lh is not more than 75% (Rh / Lh ⁇ 75%), more preferably not more than 65% (Rh / Lh ⁇ 65%).
  • homothetically approximate the orbit is meant that the arc of circle portion of the upper peripheral edge and the last orbit of particle adjacent to the point of extraction are both arcs of circle sharing the same centre with different radii. The arc of circle is thus approximately parallel to the portion of said last orbit directly adjacent to and upstream from the extraction point.
  • the length of the path of the extracted orbit and the angle between the orbit and the upper peripheral edge becomes independent of the azimuthal position of the extracting system (for example a stripper).
  • the characteristics of the extracted beam are (nearly) independent of the position of the point of extraction.
  • the arc of circle extends from the first upper distal end to the second upper distal end of the upper peripheral edge, thus defining the whole peripheral edge of a hill sector and the centre of the arc of circle lies on the bisector of the upper surface, said bisector being defined as the straight line, joining the central axis to the midpoint of the upper peripheral edge.
  • the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
  • a cyclotron accelerates the particle beam over a given path until a first point of extraction whence the particle beam can be driven out of the cyclotron with a given energy.
  • a hill sector may comprise more than one point of extraction, for example, two.
  • the arc of circle portion of the upper peripheral edges of two opposite hill sectors with respect to the median plan MP, of two magnet poles are parallel to and reproduce homothetically a portion of the given path directly upstream of the first point of extraction.
  • the arc of circle shares the same centre as, and is parallel to a portion of the given path over the whole peripheral edge.
  • upstream and "downstream" are defined with respect to the direction of the particle beam.
  • the particle beam When the particle beam has reached its target energy, it is extracted at a point of extraction and, it then follows an extraction path downstream of the point of extraction. A part of this extraction path lies between the first and second magnet poles and is thus still comprised within the hill gap portion and subjected to the magnetic field. If the pair of opposite hill sectors comprises a first and a second points of extraction, the particle beam can be extracted either at the first or at the second point of extraction or at both. The particle beam then follows either a first or a second extraction path downstream of the first or second point of extraction.
  • the length of the extraction path comprised within the gap downstream of the first point of extraction, L1 , and the length of the extraction path comprised within the gap downstream of the second point of extraction, L2, are substantially equal.
  • the main advantage of having the same length of extraction paths downstream of the first and second points of extraction is to ensure that the particle beam extracted from one point of extraction has similar optical properties as the one extracted from the second point of extraction.
  • Fig. 10 shows an example of a preferred embodiment of a magnet pole for a cyclotron wherein the upper surface of at least one hill sector further comprises:
  • fitting means that the pole insert has a general shape able to be precisely inserted into and nested in the recess.
  • all pole inserts have the same shape and are made of the same material.
  • the pole insert is made of the same material as the corresponding hill sector.
  • the recess extends along a longitudinal axis intersecting the central axis, and it is open ended at both ends and extends from the upper central edge all the way to the upper peripheral edge.
  • the longitudinal axis intersects the upper peripheral edge at a point located at equal distance from the first and second upper distal ends, and wherein the first and second upper distal ends are preferably symmetrical with respect to the longitudinal axis.
  • the pole insert has a general parallelepiped shape, as illustrated in Fig. 6(b).
  • the recess extends to and is open ended at the upper peripheral edge
  • the distal end of the pole insert 9dc forms a portion of the upper peripheral edge.
  • the portion of the upper peripheral edge formed by the pole insert is preferably not more than 10%, more preferably not more than 5% of the length, Ah, of the upper peripheral edge.
  • this distal end forms a chamfer at the peripheral surface.
  • the pole insert is nested in the recess and is reversibly fastened to the corresponding hill sector. For example, it can be coupled to the hill sector with screws.
  • the pole insert preferably has a prismatic geometry along the longitudinal axis over at least 80% of its length, L9, excluding the converging proximal portion 9p, of length L9p.
  • the ridges between the hill upper surface 3U and the hill lateral surfaces are chamfered, then the corresponding ridges of the proximal portion of the recess can be chamfered too.
  • the topography, illustrated in Fig. 6 , of the pole insert upper surface 9U and/or first and second lateral surfaces 9L can be machined to form grooves 9gu , 9gl either transverse, or parallel to the longitudinal axis, of the upper surface or of a lateral surface.
  • the grooves may extend along a straight, curved or broken line.
  • holes 9hu , 9hl can be drilled through the surfaces.
  • the holes can be blind holes (i.e., of finite depth) or can be through holes.
  • each hill sector comprises a pole insert for symmetry reasons, the pole inserts are thus machined individually or aligned side by side and all machined together. The resulting aspect of the machined pole insert may differ considerably from its aspect before machining.
  • the present invention offers the advantages that it allows the reduction of the size of the vacuum chamber and a decrease of the overall weight of the cyclotron.
  • the position of the recesses can be precisely manufactured and positioned.
  • the magnetic field is deviated inwards by recessed gradient correctors resulting in an inwards shift of the last cycles of the particles path where the magnetic field is more uniform than close to the peripheral edge. It is therefore easier and more predictable to control the properties of the extracted particle beam, and particularly the focusing thereof.

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Particle Accelerators (AREA)

Abstract

A magnet pole for an isochronous sector-focused cyclotron comprising hill and valley sectors alternatively distributed around a central axis, Z, each hill sector comprises an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges, and a peripheral surface extending from the upper peripheral edge to a lower peripheral line. The upper peripheral edge of at least one hill sector further comprises a concave portion with respect to the central axis defining a recess extending at least partially over a portion of the peripheral surface of the corresponding hill sector

Description

    Field of the invention
  • The present invention concerns cyclotrons. In particular, it concerns isochronous sector-focused cyclotrons having enhanced focusing of an extracted beam of energized charged particles.
  • Technnical background
  • A cyclotron is a type of circular particle accelerator in which negatively or positively charged particles are accelerated outwards from the centre of the cyclotron along a spiral path up to energies of several MeV. Unless otherwise indicated, the term "cyclotron" is used in the following to refer to isochronous cyclotrons. Cyclotrons are used in various fields, for example in nuclear physics, in medical treatment such as proton-therapy, or in radio-pharmacy. In particular, cyclotrons can be used for producing short-lived positron-emitting isotopes suitable for PET imaging (positron emitting tomography) or for producing gamma-emitting isotopes, for example, Tc99m, for SPECT imaging (single photon emission computed tomography).
  • A cyclotron comprises several elements including an injection system, a radiofrequency (RF) accelerating system for accelerating the charged particles, a magnetic system for guiding the accelerated particles along a precise path, an extraction system for collecting the thus accelerated particles, and a vacuum system for creating and maintaining a vacuum in the cyclotron.
  • A particle beam constituted of charged ions is introduced into a gap at or near the center of the cyclotron by the injection system with a relatively low initial velocity. As illustrated in Fig. 3, this particle beam is sequentially and repetitively accelerated by the RF accelerating system and guided outwards along a spiral path comprised within the gap by the magnetic field generated by the magnetic system. When the particle beam reaches its target energy, it can be extracted from the cyclotron by the extraction system provided at a point of extraction, PE. This extraction system can comprise, for example, a stripper consisting of a thin sheet of graphite. For example, H- ions passing through the stripper lose two electrons and become positive. Consequently, the curvature of their path in the magnetic field changes its sign, and the particle beam is thus led out of the cyclotron towards a target. Other extracting systems exist which are well known to the persons skilled in the art.
  • The magnetic system generates a magnetic field that guides and focuses the beam of charged particles along the spiral path until it is accelerated to its target energy. In the following, the terms "particles", "charged particles", and "ions" are used indifferently as synonyms. The magnetic field is generated in the gap defined between two magnet poles by two solenoid coils, 14, wound around these poles. Magnet poles of cyclotrons are often divided into alternating hill sectors and valley sectors distributed around a central axis. The gap between two magnet poles is smaller at the hill sectors and the larger at the valley sectors. A strong magnetic field is thus created in the hill gap portions within the hill sectors and a weaker magnetic field is created in the valley gap portions within the valley sectors. Such azimuthal magnetic field variations provide radial and vertical focusing of the particle beam every time the particle beam reaches a hill gap portion. For this reason, such cyclotrons are sometimes referred to as sector-focusing cyclotrons. In some embodiments, a hill sector has a geometry of a circular sector similar to a slice of cake with a first and second lateral surfaces extending substantially radially towards the central axis, a generally curved peripheral surface, a central surface adjacent to the central axis, and an upper surface defining one side of a hill gap portion. The upper surface is delimited by a first and second lateral edges, a peripheral edge, and a central edge.
  • In practice, a particle beam has a cross sectional area. An objective of cyclotrons is to produce charged particle beams having a given energy which are as much focused as possible (i.e. having a small cross sectional area) The variations of the magnetic field created by the succession of hill sectors and valley sectors contributes to the focusing of the beam in a similar way as a light beam can be focused by lenses. Upon extraction of the particle beam out of the gap defined between two magnet poles, however, the particle beam crosses boundary regions where the magnetic field loses its homogeneity, which is detrimental to the focusing of the particle beam. This is a particularly sensitive issue because, on the one hand, the particle beam has its highest energy at the point of extraction and, on the other hand, it is more difficult to control the magnetic field at the peripheral edges of the magnet poles where the magnetic field drops rapidly. To enhance the focusing of an extracted particle beam, it has been proposed in the art to modify the geometry of the peripheral edges of hill sectors by forming protrusions to said peripheral edges by addition of gradient correctors. Gradient correctors are relatively small blocks of steel with respect to the size of a hill sector, which are coupled to the peripheral surfaces of the hill sectors. Such gradient correctors allow the modification of the magnetic field near the peripheral edges and thus locally modify the magnetic field near the peripheral edge of a hill sector to improve the focusing of the outgoing particle beam. The use of protruding gradient correctors has, however, several drawbacks. First, the volume of the vacuum chamber hosting the magnet poles must be increased accordingly, thus requiring more energy and time to pump the gases from the vacuum chamber. Second, the overall weight of the cyclotron is increased because of, on the one hand, the weight of the gradient correctors themselves and, on the other hand, the increased overall size of the outer walls of the vacuum chamber and, consequently, the size of the flux return yoke; both contributing to a substantial increase of the cyclotron weight. Third, the position of the protruding gradient correctors is essential; small deviations ofposition may yield large variations of the magnetic field. Gradient correctors must be fixed manually by a skilled artisan at precisely the same position of the peripheral surface of all the hill sectors. This is of course, a critical and expensive operation. Fourth, these protruding gradient correctors have the effect of deviating the magnetic field outwards, which pulls outwards the path of the particle beam towards the peripheral edge of a hill gap portion between a pair of opposed hill sectors where the magnetic field loses its homogeneity. This shift also leads to a loss of useful magnetic field and thus requires an increase of the coil current in order to compensate this loss. It is therefore more difficult and expensive to control the properties of the extracted particle beam.
  • There therefore remains a need in the art to provide an isochronous sector-focused cyclotron allowing the extraction of a more focused and more predictable particle beam in an efficient and cost effective manner.
  • Summary of the invention
  • The present invention is defined in the appended independent claims. Preferred embodiments are defined in the dependent claims.
  • The present invention concerns a magnet pole for a cyclotron comprising at least 3 hill sectors and a same number of valley sectors comprising a bottom surface, said hill sectors and valley sectors being alternatively distributed around a central axis, Z, each hill sector comprising:
    1. (a) an upper surface defined by:
      • an upper peripheral edge, said upper peripheral edge being bounded by a first and a second upper distal ends, and being defined as the edge of the upper surface located furthest from the central axis;
      • an upper central edge, said upper central edge being bounded by a first and a second upper proximal ends and being defined as the edge of the upper surface located closest from the central axis;
      • a first upper lateral edge connecting the first upper distal end and first upper proximal end;
      • a second upper lateral edge connecting the second upper distal end and second upper proximal end;
    2. (b) a first and second lateral surfaces each extending transversally from the first and second upper lateral edges, to the bottom surfaces of the corresponding valley sectors located on either sides of a hill sector, thus defining a first and second lower lateral edges as the edges intersecting a lateral surface with an adjacent bottom surface, said first and second lower lateral edges each having a lower distal end located furthest from the central axis;
    3. (c) a peripheral surface extending from the upper peripheral edge to a lower peripheral line defined as the segment bounded by the lower distal ends of the first and second lower lateral edges;
    characterised in that, the upper peripheral edge of at least one hill sector comprises a concave portion with respect to the central axis defining a recess extending at least partially over a portion of the peripheral surface of the corresponding hill sector.
  • Preferably, the recess is generally wedge shaped with a first and second converging lines (preferably straight lines) extending away from the upper peripheral edge, with a converging angle, θ, preferably comprised between 70° and 130°, more preferably between 80°and 110°, most preferably 90°± 5°.
  • The recess has a converging portion, away from the upper peripheral edge, said converging portion having one of the following geometry:
    • a sharp corner forming a triangular recess;
    • a straight edge forming a trapezoidal recess; or
    • a rounded edge forming an arched recess.
  • Preferably, the upper peripheral edge has an azimuthal length, Ah, and wherein the concave portion extends between 3% and 30% of the azimuthal length of the upper peripheral edge, preferably, between 5% and 20%, more preferably, between 8% and 15%.
  • Preferably, the recess is separated from the first and second upper lateral edges. Alternatively, the recess is adjacent to the first upper lateral edge.
  • The recess can extend over a portion of the peripheral surface.
  • Preferably, the portion of the peripheral surface correspond to a fraction, ξ, of the height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and the lower peripheral line, wherein the fraction, ξ, is comprised between 25% and 75%, preferably between 40% and 60%, most preferably between 45% and 55%.
  • In order to have smooth variations of the magnetic field, the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
  • Preferably, the upper peripheral edge is an arc of circle which centre is offset with respect to the central axis, and which radius is not more than 85% of a distance from the central axis to a midpoint of the upper peripheral edge, which is equidistant to the first and second upper distal ends.
  • The number, N, of hill sectors is preferably 3, 4, 5, 6, 7, or 8, more preferably N = 4.
  • The invention also relates to a cyclotron for accelerating a particle beam over a given path comprised within a gap, said cyclotron comprising first and second magnet poles such as described above, wherein the first and second magnet poles are positioned symmetrically with respect to a median plane normal to the central axes of first and second magnet pole forming said gap in between, with hill gap portion being formed between two opposite hill sectors and valley gap portions being formed between two opposite valley sectors.
  • Preferably, the recess of a cyclotron has a first and a second recess distal points, said first and second recess distal points being separated from one another by a distance L10, and wherein the hill gap portion between a pair of hill sectors of the first and second magnet poles has an average height, Gh, and wherein the ratio Gh / L10 is comprised between 5 and 100 %, preferably between 10 and 50 %, more preferably, 20 and 33 %.
  • The cyclotron can also comprise a point of extraction, located in a hill gap portion between two opposite upper surfaces of hill sectors of the first and second magnet poles, wherein the given path of the particle beam is an outward spiral path cycling about the central axis until said first point of extraction whence the particle beam can be driven out of the cyclotron with a given energy along an extraction path, and wherein the recess is located downstream from said point of extraction wherein downstream is defined with respect to the direction of the particle beam, such that the extraction path crosses on line of the recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  • Preferably, the cyclotron further comprises a second point of extraction in a hill sector defining a second extraction path, and comprising a second recess located downstream from the second point of extraction, such that the second extraction path crosses one line of the second recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  • Short description of the drawings
  • These and further aspects of the invention will be explained in greater detail by way of example and with reference to the accompanying drawings in which:
    • Fig. 1 schematically shows (a) a side cut view and (b) a top view of a cyclotron according to the invention;
    • Fig. 2 shows an example of hill and valley sectors of a cyclotron according to the invention;
    • Fig. 3 shows a partial perspective view of a half cyclotron and the path of accelerates charged particles (the outlets for the extracted particles in the flux return yokes are not shown for enhancing visibility);
    • Fig. 4 shows an example of a hill sector according to the present invention comprinsing a gradient corrector;
    • Fig. 5 shows an example of lines of a magnetic field with and without gradient corrector;
    • Fig. 6 shows examples of geometries of the concave portion of the upper peripheral line of a hill sector according to the present invention;
    • Fig. 7 shows examples of geometries of the recess according to the present invention;
    • Fig. 8 shows an example of a magnet pole according to the present invention having two recesses and two points of extraction
    • Fig. 9 shows another example of a hill sector according to the present invention comprising an improved upper peripheral edge design of a hill sector;
    • Fig. 10 shows a third example of a hill sector according to the present invention and having a recess (a) and a pole insert (b).
    Detailed description Geometry of a cyclotron according to the present invention
  • The present invention concerns isochronous sector-focused cyclotrons, hereafter referred to as cyclotron of the type discussed in the technical background section supra. As illustrated in Fig. 3, a cyclotron according to the present invention accelerates charged particles outwards from a central area of the cyclotron along a spiral path 12 until they are extracted at energies of several MeV. For example, the charged particles thus extracted can be protons, H+, or deuteron, D+. Preferably, the energy reached by the extracted particles is comprised between 5 and 30 MeV, more preferably between 15 and 21 MeV, most preferably 18 MeV. Cyclotrons of such energies are used, for example, for producing short-lived positron-emitting isotopes suitable for use in PET imaging (positron emitting tomography) or for producing gamma-emitting isotopes, for example, Tc99m, for SPECT imaging (single photon emission computed tomography).
  • As illustrated in Fig. 1 a cyclotron 1 according to the present invention comprises two base plates 5 and flux return yokes 6 which, together, form a yoke. The flux return yokes form the outer walls of the cyclotron and control the magnetic field outside of the coils 14 by containing it within the cyclotron. It further comprises first and second magnet poles 2 located in a vacuum chamber, facing each other symmetrically with respect to a median plane MP normal to a central axis, Z, and separated from one another by a gap 7. The yoke and the magnet poles are all made of a magnetic material, preferably a low carbon steel and form a part of the magnetic system. The magnetic system is completed by a first and second coils 14 made of electrically conductive wires wounded around the first and second magnet poles and fitting within an annular space defined between the magnet poles and the flux return yokes.
  • As illustrated in Fig. 1(b) and Fig. 2, each of the first and second magnet poles 2 comprises at least N = 3 hill sectors 3 distributed radially around the central axis, Z (Fig. 1(b) illustrates a preferred embodiment with N = 4). Each hill sector 3, represented in Fig. 1(b) as light shaded areas, has an upper surface 3U extending over a hill azimuthal angle, αh. Each of the first and second magnet poles 2 further comprises the same number, N, of valley sectors 4, represented in Fig. 1(b) as dark shaded areas, distributed radially around the central axis Z. Each valley sector 4 is flanked by two hill sectors 3 and has a bottom surface 4B extending over a valley azimuthal angle, αv, such that αh + αv = 360°/N.
  • The hill sectors 3 and valley sectors 4 of the first magnet pole 2 face the opposite hill sectors 3 and valley sectors 4, respectively, of the second magnet pole 2. The path 12 followed by the particle beam illustrated in Fig. 3 is comprised within the gap 7 separating the first and second magnet poles. The gap 7 between the first and second magnet poles thus comprises hill gap portions 7h defined between the upper surfaces 3U of two opposite hill sectors 3 and valley gap portions 7v defined between the bottom surfaces 4B of two opposite valley sectors 4. The hill gap portions 7h have an average gap height, Gh, defined as the average height of the hill gap portions over the areas of two opposite upper surfaces 3U.
  • Average hill and valley gap heights are measured as the average of the gap heights over the whole upper surface and lower surface of a hill sector and a valley sector, respectively. The average of the valley gap height ignores any opening on the bottom surfaces.
  • The upper surface 3U is defined by (see Fig. 2):
    • an upper peripheral edge 3up, said upper peripheral edge being bounded by a first and a second upper distal ends 3ude, and being defined as the edge of the upper surface located furthest from the central axis Z;
    • an upper central edge 3uc, said upper central edge being bounded by a first and a second upper proximal ends 3upe and being defined as the edge of the upper surface located closest from the central axis;
    • strai
    • a second upper lateral edge 3ul connecting the second upper distal end and second upper proximal end.
  • A hill sector 3 further comprises (see Fig. 2):
    • a first and second lateral surfaces 3L each extending transversally from the first and second upper lateral edges, to the bottom surfaces of the corresponding valley sectors located on either sides of a hill sector, thus defining a first and second lower lateral edges 311 as the edges intersecting a lateral surface with an adjacent bottom surface, said first and second lower lateral edges each having a lower distal end 31de located furthest from the central axis;
    • a peripheral surface 3P extending from the upper peripheral edge to a lower peripheral line 31p defined as the segment bounded by the lower distal ends 31de of the first and second lower lateral edges.
  • The average height of a hill, Hh, sector is the average distance measured parallel to the central axis between lower and upper lateral edges.
  • An end of an edge is defined as one of the two extremities bounding a segment defining the edge. A proximal end is the end of an edge located closest from the central axis, Z. A distal end is the end of an edge located furthest from the central axis, Z. An end can be a corner point which is defined as a point where two or more lines meet. A corner point can also be defined as a point where the tangent of a curve changes sign or presents a discontinuity.
  • An edge is a line segment where two surfaces meet. An edge is bounded by two ends, as defined supra, and defines one side of each of the two meeting surfaces. For reasons of machining tools limitations, as well as for reduction of stress concentrations, two surfaces often meet with a given radius of curvature, R, which makes it difficult to define precisely the geometrical position of the edge intersecting both surfaces. In this case, the edge is defined as the geometric line intersecting the two surfaces extrapolated so as to intersect each other with and infinite curvature (1/R). An upper edge is an edge intersecting the upper surface 3U of a hill sector, and a lower edge is an edge intersecting the bottom surface 4B of a valley sector.
  • A peripheral edge is defined as the edge of a surface comprising the point located the furthest from the central axis, Z. If the furthest point is a corner point shared by two edges, the peripheral edge is also the edge of a surface which average distance to the central axis, Z, is the largest. For example, the upper peripheral edge is the edge of the upper surface comprising the point located the furthest to the central axis. If a hill sector is compared to a slice of tart, the peripheral edge would be the peripheral crust of the tart.
  • In an analogous manner, a central edge is defined as the edge of a surface comprising the point located the closest to the central axis, Z. For example, the upper central edge is the edge of the upper surface comprising the point located the closest to the central axis, Z.
  • A lateral edge is defined as the edge joining a central edge at a proximal end to a peripheral edge at a distal end. The proximal end of a lateral edge is therefore the end of said lateral edge intersecting a central edge, and the distal end of said lateral edge is the end of said lateral edge intersecting a peripheral edge.
  • Depending on the design of the cyclotron, the upper / lower central edge may have different geometries. The most common geometry is a concave line (or concave curve), often circular, of finite length (≠0), with respect to the central axis, which is bounded by a first and second upper / lower proximal ends, separated from one another. This configuration is useful as it clears space for the introduction into the gap of the particle beam and other elements. In a first alternative configuration, the first and second proximal central ends are merged into a single proximal central point, forming a summit of the upper surface 3U, which comprises three edges only, the central edge having a zero-length. If a hill sector is again compared to a slice of tart, the pointed tip of the slice would correspond to the central edge thus reduced to a single point. In a second alternative configuration, the transition from the first to the second lateral edges can be a curve convex with respect to the central axis, Z, leading to a smooth transition devoid of any corner point. In this configuration, the central edge is also reduced to a single point defined as the point wherein the tangent changes sign. Usually, even in the first and second alternative configurations, a hill sector does not extend all the way to the central axis, the central area directly surrounding the central axis is cleared to allow insertion of the particle beam or installation of other elements.
  • As shown is Fig. 2, the first and second lateral surfaces 3L are preferably chamfered forming a chamfer 3ec at the first and second upper lateral edges, respectively. A chamfer is defined as an intermediate surface between two surfaces obtained by cutting off the edge which would have been formed by the two surfaces absent a chamfer. A chamfer reduces the angle formed at an edge between two surfaces. Chamfers are often used in mechanics for reducing stress concentrations. In cyclotrons, however, a chamfered lateral surface at the level of the upper surface of a hill sector enhances the focusing of the particle beam as it reaches a hill gap portion 7h. The peripheral surface 3P of a hill sector can also form a chamfer at the upper peripheral edge, which improves the homogeneity of the magnetic field near the peripheral edge.
  • A cyclotron according to the present invention preferably comprises N = 3 to 8 hill sectors 3. More preferably, as illustrated in the Figures, N = 4. For even values of N, the hill sectors 3 and valley sectors 4 must be distributed about the central axis with any symmetry of 2n, with n = 1 to N/2. Preferably, n = N/2, such that all the N hill sectors are identical to one another, and all the N valley sectors are identical to one another. For odd values ofN, the hill sectors 3 and valley sectors 4 must be distributed about the central axis with a symmetry of N. In a preferred embodiment, the N hill sectors 3 are uniformly distributed around the central axis for all N = 3-8 (i.e., with a symmetry ofN). The first and second magnet poles 2 are positioned with their respective upper surfaces 3U facing each other and symmetrically with respect to the median plane MP normal to the respective central axes Z of the first and second magnet poles 2, which are coaxial.
  • The shape of the hill sectors is often wedge shaped like a slice of tart (often, as discussed supra, with a missing tip) with the first and second lateral surfaces 3L converging from the peripheral surface towards the central axis Z (usually without reaching it). The hill azimuthal angle, αh, corresponds to the converging angle, measured at the level of the intersection point of the (extrapolated) upper lateral edges of the lateral surfaces at, or adjacent to, the central axis Z. The hill azimuthal angle, αh, is preferably comprised between 360°/2N±10°, more preferably between 360° / 2N ± 5°, most preferably between 360° / 2N ± 2°.
  • The valley azimuthal angle αv, measured at the level of the central axis Z is preferably comprised between 360° / 2N ± 10°, more preferably between 360° / 2N ± 5°, most preferably between 360° / 2N ± 2°. The valley azimuthal angle αv can be equal to the hill azimuthal angle, αh. In case of a degree of symmetry of N, αv = 360°/N - αh; for example, for N = 4, αv is the complementary angle of αh, with αv = 90° - αh.
  • The largest distance, Lh, between the central axis and a peripheral edge is preferably comprised between 200 and 2000 mm, more preferably between 400 and 1000 mm, most preferably between 500 and 800 mm. For a 18 MeV proton cyclotron, the longest distance, Lh, is usually less than 750 mm, and can be of the order of 500 to 750 mm, typically 520 to 550 mm. The upper peripheral edge has an azimuthal length, Ah, measured between the first and second upper peripheral ends, and can be approximated to, Ah = Lh x αh [rad].
  • The two magnet poles 2 and solenoid coils 14 wound around each magnet pole,_form an (electro-)magnet which generates a magnetic field in the gap 7 between the magnetic poles that guides and focuses the beam of charged particles (= particle beam) along a spiral path 12 illustrated in Fig. 3, starting from the central area (around the central axis, Z) of the cyclotron, until it reaches a target energy, for example of 18 MeV, whence it is extracted. As discussed supra, the magnet poles are divided into alternating hill sectors and valley sectors distributed around the central axis, Z. A strong magnetic field is thus created in the hill gap portions 7h of average height Gh within the hill sectors and a weaker magnetic field is created in the valley gap portions 7v of average height Gv > Gh, within the valley sectors thus creating vertical focusing of the particle beam.
  • When a particle beam is introduced into a cyclotron, it is accelerated by an electric field created between high voltage electrodes called dees (not shown), and ground voltage electrodes attached to the lateral edges of the poles, positioned in the valley sectors, where the magnetic field is weaker. Each time an accelerated particle penetrates into a hill gap portion 7h it has a higher speed than it had in the preceding hill sector. The high magnetic field present in a hill sector deviates the trajectory of the accelerated particle to follow an essentially circular path of radius larger than it followed in the preceding hill sector. Once a particle beam has been accelerated to its target energy, it is extracted from the cyclotron at a point called point of extraction PE, as shown in Fig. 3. For example, energetic protons, H+, can be extracted by driving a beam of accelerated H- ions through a stripper consisting of a thin foil sheet of graphite. A H- ion passing through the stripper loses two electrons to become a positive, H+. By changing the sign of particle charge, the curvature of its path in the magnetic field changes sign, and the particle beam is thus led out of the cyclotron towards a target (not shown). Other extracting systems are known by the persons skilled in the art and the type and details of the extraction system used is not essential to the present invention. Usually, a point of extraction is located in a hill gap portion 7h. A cyclotron can comprise several points of extraction in a same hill portion. Because of the symmetry requirements of a cyclotron, more than one hill sector comprises an extraction point. For degrees of symmetry of N, all N hill sectors comprise the same number of points of extraction. The points of extraction can be used individually (one only at a time) or simultaneously (several at a time).
  • Gradient corrector
  • Fig. 4(a) and Fig. 4(b) show an example of a preferred embodiment of a magnet pole for a cyclotron comprising N = 4 hill sectors and N = 4 valley sectors comprising a bottom surface, said hill sectors and valley sectors alternatively distributed around a central axis, Z, with a symmetry of N = 4. Such hill sector of cyclotron according to the present invention comprises a first and second lateral surfaces 3L, a peripheral surface 3P and an upper surface 3U such as defined above. The upper peripheral edge 3up of the upper surface of at least one hill sector comprises a convex portion adjacent to a concave portion with respect to the central axis defining a recess extending partially over a portion of the peripheral surface of the corresponding hill sector. Preferably, The upper peripheral edge 3up of the upper surface of at least one hill sector comprises 2 convex portions separated by a concave portion.
  • Because of the symmetry requirements of 2n for even values of N and ofN for odd values of N, discussed supra, the same symmetry must apply to the presence or not of a concave portion with respect to the central axis on the upper peripheral edges of the various hill sectors. Therefore, the upper peripheral edge of each hill sector, preferably, comprises a concave portion 3upc with respect to the central axis defining a recess 10 extending partially over the peripheral surface of the corresponding hill sector between two convex portions.
  • The term "concave" means curving in or hollowed inward. The concave portion with respect to the central axis of an edge, is a portion of the edge curving towards the central axis. This term is opposed to the term "convex" that means curving out of or extending outward from the central axis.
  • The position of the recess can either be separated from the first and second lateral edges, or adjacent to the first or second lateral edge. Preferably, a hill sector comprises at least one recess separated from the lateral edges.
  • In prior art cyclotrons, protruding gradient correctors were used. Protruding gradient correctors have several drawbacks:
    • increase of the volume of the vacuum chamber,
    • increase of the volume of the yoke, and of the whole cyclotron,
    • increase of the weight of the cyclotron,
    • difficulty of precise positioning of the gradient correctors which must be done manually,
    • outwards deviation of the magnetic field.
  • Using recessed gradient correctors instead of protruding gradient correctors has several advantages. First, it allows the reduction of the size of the vacuum chamber hosting the magnet poles leading to a decrease of energy required for evacuating the gases from the vacuum chamber and reducing the time of the gas evacuation. Second, the overall weight of the cyclotron is decreased because, on the one hand, the weight of the hill sectors is slightly reduced instead of being increased and, on the other hand, the overall diameter of the inner surface of flux return yoke is decreased. Third, the position of the recesses can be precisely manufactured and positioned by numerically controlled machining allowing the optimization of the angle at which the particle beam crosses the peripheral edge of the hill sector. Fourth, when protruding gradient correctors deviate the magnetic field outwards, the magnetic field is deviated inwards by recessed gradient correctors resulting in an inwards shift of the last cycles of the particles path, further away from the peripheral edge of the hill sector, where the magnetic field is more uniform than close to the peripheral edge. Fig. 4 shows an example of the lines of the magnetic field deviated by the recessing gradient corrector (Fig. 5(a)) and without any gradient corrector (Fig. 5(b)). It is therefore easier and more predictable to control the properties of the extracted particle beam, and particularly the focusing thereof. This deviation towards the acceleration area also allows the power fed to the coils to be decreased.
  • Preferably, the upper peripheral edge 3up comprises a first and a second recess distal points 10rdp, defining the boundaries of a recess, and which are defined as the points where the tangent of the upper peripheral edge changes sign or presents a discontinuity. The first and second recess distal points are separated from one another by a distance L10. The recess also comprises a recess proximal point 10rpp defined as the point of the recess located closest to the central axis, Z. The first and second recess distal points 10rdp join the recess proximal point 10rpp by a first and second recess converging edges 10rc.
  • The recess depth, H10, is defined as the height of the triangle formed by the first and second recess distal points 10rdp and the recess proximal point 10rpp, and passing by the recess proximal point 10rpp. The depth of the recess, H10 is comprised between 3% and 30%, preferably, between 5% and 20%, more preferably, between 8% and 15% of the azimuthal length, Ah, of the upper peripheral edge. Preferably, the ratio of the recess depth, H10, to the largest distance, Lh, between the central axis and a peripheral edge of a hill sector, H10 / Lh, is comprised between between 2% and 20%, preferably, between 4% and 15%, more preferably, between 6% and 10%.
  • The upper peripheral edge 3up has an azimuthal length, Ah, measured between the first and second upper distal ends 3ude. The first recess converging edge 10r1 joining the first recess distal point to the recess proximal point has a length L101 and the second recess converging edge 10r2 joining the second recess distal point to the recess proximal point has a length L102. The lengths L101 and L102 of the first and second recess converging edges are comprised between 5 and 30% of the azimuthal length, Ah, of the upper peripheral edge. Preferably, the length L101 is equal ± 40% to the length L102 (L101 = L102 ± 40%).
  • Preferably, the distance L10 between first and second recess distal points ranges between 5% and 50%, more preferably, between 10% and 30%, most preferably, between 15% and 20% of the azimuthal length, Ah, of the upper peripheral edge.
  • Preferably, the recess also extends over a portion of the peripheral surface 3P from the upper peripheral edge 3up towards the lower peripheral line 31p. The recess thus extends over the peripheral surface over a fraction, ξ, of a height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and lower peripheral line. The fraction, ξ, is preferably, comprised between 25% and 100%, preferably between 40% and 75%, most preferably between 45% and 55%.
  • As illustrated in Fig. 6, the concave portion of the upper peripheral edge can have any of the following geometries open between the first and second recess distal points: (a) a rectangle, (b) a trapeze, (c) a triangle having straight edges or curved (inwards or outwards) edges, (d) an arc of circle, (e) two arcs of circle, (f) a parabola, (g) a square, (h) a parallelogram, (i) a polygon, (j) a smooth curve. Basically, any geometry determined by numerical analysis can be implemented. For example, in the case of a trapeze, the small base can comprise the recess proximal point 10rpp, and the large base can be defined by the first and second recess distal points 10rdp. Alternatively, the small base can be defined by the first and second recess distal points 10rdp, and the large base can comprise the recess proximal point 10rpp. A triangle can be scalene, isosceles or equilateral. It can also be right, with the right angle formed at the recess proximal point 10rpp. In the case of two (or more) arc of circle, they can be curved inwards ((e) right) or outwards ((e) left). The concave portion is preferably designed such that one edge thereof intersects the extraction path of a particle beam with an angle of 80-100°, preferably 85-95°, substantially 90°.
  • Preferably, a recess 10 extends over a portion of the peripheral surface parallel to the central axis. Alternatively, it can extend downwards from the upper surface with an angle with the central axis, Z. The distance L10 and/or the height H10 can increase or decrease independently of one another or simultaneously along the height of the peripheral surface. The area of the cross-section of the recess normal to the central axis, Z, can thus decrease or increase with the distance from the upper surface. In a more complex embodiment, the geometry and the area of the cross-section of the recess can change over the peripheral surface. The height of the recess can also vary over the peripheral surface. Fig. 7 illustrates some examples of geometries of recesses. For example, the recess can have a shape of: (a) a prism extending from the upper surface parallel to the central axis, (b) a prism extending from the peripheral surface normal to the central axis, (c) a (portion of) pyramid, or more complex volumes extending over the peripheral surface.
  • Preferably, the recess is generally wedge shaped with the first and second recess converging edges being straight (or slightly curved inwards or outwards) lines. The tip of the wedge corresponds to the recess proximal point and points at the general direction of the central axis. The converging angle, θ, at the tip of the wedge is preferably comprised between 70° and 130°, more preferably between 80° and 110°, most preferably 90°± 5°. The expressions "inwards" and "outwards" used herein are to be understood as "towards" or "away from" the central axis, respectively.
  • More generally, the converging portion of the wedge-shaped recess can have one of the following geometries:
    • a sharp corner forming a triangular recess, corresponding to the wedge shaped recess discussed supra;
    • a straight edge forming a trapezoidal recessed wedge; or
    • a rounded edge wedge forming an arched recess.
  • The present invention also concerns a cyclotron comprising magnet poles as defined supra. As described supra, a cyclotron accelerates a particle beam over a given path until a first point of extraction whence the particle beam is driven out of the cyclotron with a given energy. The hill gap portion between a pair of hill of the first and second magnet poles of a cyclotron has an average height, Gh. Preferably, the ratio of the distance L10 between first and second recess distal points 10rdp to the height of hill gap portion Gh, is comprised between 1 and 20, preferably between 2 and 10, more preferably, 3 and 5. For example, for a hill gap of height Gh = 20-40 mm, the distance L10, can be of the order of 10-100 mm, yielding a ratio L10/Gh which can be comprised between 1-5, preferably between 3 and 3.5, i.e. Gh / L10 ≤ 1.
  • Preferably, a point of extraction is located within a hill gap portion adjacent to the peripheral edges of a pair of opposed hill sectors. A recess is located downstream from said first point of extraction wherein downstream is defined with respect to the direction of the particle beam. The recess 10 is precisely machined with respect to the point of extraction and to the extraction path such that the particle beam intersects the first converging recess edge 10r1 with an angle of 90° ± 15°. The particle beam thus leaves the hill gap portion substantially normal to the magnetic field, which improves the focusing of the extracted particle beam. The position and the geometry of the recess are determined by numerical computation and/or testing.
  • As shown in Fig. 8, the cyclotron may further comprise a second point of extraction, PE2, located downstream from the first point of extraction, PE1, and within the same hill gap portion of the same pair of opposed hill sectors. The particle beam can be driven out of the cyclotron at said second point of extraction with the same energy as at said first point of extraction. In this case, the hill sector comprising the two extraction points, also comprises two recesses, each located downstream from a corresponding point of extraction.
  • Fig. 9 shows an example of a preferred embodiment of a magnet pole for a cyclotron according to the present invention. In this embodiment, the upper peripheral edge 3up is bounded by a first and a second upper distal ends, and the upper peripheral edge of a hill sector comprises an arc of circle 3ac which centre is offset with respect to the central axis, and which radius, Rh, is not more than 85 % of a distance, Lh, from the central axis to a midpoint of the upper peripheral edge, which is equidistant to the first and second upper distal ends (Rh / Lh ≤ 85%).
  • Preferably, the ratio Rh / Lh of the radius, Rh, to the distance Lh, is not more than 75% (Rh / Lh ≤ 75%), more preferably not more than 65% (Rh / Lh ≤ 65%).
  • The aim of having the upper peripheral edge comprising an arc of circle which centre is offset with respect to the central axis is to homothetically approximate at least a portion of the upper peripheral edge to the highest energy (= last) orbit of the spiral path 12 in a hill gap portion 7h of the cyclotron. By "homothetically approximate the orbit" is meant that the arc of circle portion of the upper peripheral edge and the last orbit of particle adjacent to the point of extraction are both arcs of circle sharing the same centre with different radii. The arc of circle is thus approximately parallel to the portion of said last orbit directly adjacent to and upstream from the extraction point. The length of the path of the extracted orbit and the angle between the orbit and the upper peripheral edge becomes independent of the azimuthal position of the extracting system (for example a stripper). In consequence, the characteristics of the extracted beam are (nearly) independent of the position of the point of extraction.
  • Preferably, the arc of circle extends from the first upper distal end to the second upper distal end of the upper peripheral edge, thus defining the whole peripheral edge of a hill sector and the centre of the arc of circle lies on the bisector of the upper surface, said bisector being defined as the straight line, joining the central axis to the midpoint of the upper peripheral edge.
  • Preferably, the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
  • As described supra, a cyclotron accelerates the particle beam over a given path until a first point of extraction whence the particle beam can be driven out of the cyclotron with a given energy. Advantageously, a hill sector may comprise more than one point of extraction, for example, two. The arc of circle portion of the upper peripheral edges of two opposite hill sectors with respect to the median plan MP, of two magnet poles are parallel to and reproduce homothetically a portion of the given path directly upstream of the first point of extraction. The arc of circle shares the same centre as, and is parallel to a portion of the given path over the whole peripheral edge. The terms "upstream" and "downstream" are defined with respect to the direction of the particle beam.
  • When the particle beam has reached its target energy, it is extracted at a point of extraction and, it then follows an extraction path downstream of the point of extraction. A part of this extraction path lies between the first and second magnet poles and is thus still comprised within the hill gap portion and subjected to the magnetic field. If the pair of opposite hill sectors comprises a first and a second points of extraction, the particle beam can be extracted either at the first or at the second point of extraction or at both. The particle beam then follows either a first or a second extraction path downstream of the first or second point of extraction. With the circular geometry of at least a portion of the upper peripheral edge according to the present embodiment, the length of the extraction path comprised within the gap downstream of the first point of extraction, L1, and the length of the extraction path comprised within the gap downstream of the second point of extraction, L2, are substantially equal.
  • The main advantage of having the same length of extraction paths downstream of the first and second points of extraction is to ensure that the particle beam extracted from one point of extraction has similar optical properties as the one extracted from the second point of extraction.
  • Fig. 10 shows an example of a preferred embodiment of a magnet pole for a cyclotron wherein the upper surface of at least one hill sector further comprises:
    • a recess 8 extending over a length L8 between a recess proximal end 8rpe and a recess distal end 8rde along a longitudinal axis 8rl intersecting the upper peripheral edge and the upper central edge; said recess is separate from the first and second upper lateral edges over at least 80% of its length, L8, and
    • a pole insert 9 having a geometry fitting said recess and being positioned in, and reversibly coupled to said recess.
  • The term "fitting" means that the pole insert has a general shape able to be precisely inserted into and nested in the recess.
  • In prior art cyclotrons comprising pole inserts, the pole inserts were positioned in a recess machined off a lateral edge of the upper surface of the hill sectors. Access to such pole inserts is, however, rendered difficult by part of the RF accelerating system overlapping the upper lateral edge area. Access to such pole inserts requires removing the overlapping part of the RF system first. By positioning a pole insert on the upper surface, it can be accessed easily and directly for removal, machining and reinsertion into the recess. With the present embodiment, it is thus much easier and efficient to reach the optimal insert topography yielding the predicted magnetic field and particle path.
  • Preferably, all pole inserts have the same shape and are made of the same material. Preferably, the pole insert is made of the same material as the corresponding hill sector.
  • Preferably, the recess extends along a longitudinal axis intersecting the central axis, and it is open ended at both ends and extends from the upper central edge all the way to the upper peripheral edge. In yet a preferred embodiment, the longitudinal axis intersects the upper peripheral edge at a point located at equal distance from the first and second upper distal ends, and wherein the first and second upper distal ends are preferably symmetrical with respect to the longitudinal axis. For example, except for the proximal portion 9p adjacent to the central edge, the pole insert has a general parallelepiped shape, as illustrated in Fig. 6(b).
  • In the embodiment of Fig. 6(a), the recess extends to and is open ended at the upper peripheral edge, the distal end of the pole insert 9dc forms a portion of the upper peripheral edge. The portion of the upper peripheral edge formed by the pole insert is preferably not more than 10%, more preferably not more than 5% of the length, Ah, of the upper peripheral edge. Preferably this distal end forms a chamfer at the peripheral surface.
  • The pole insert is nested in the recess and is reversibly fastened to the corresponding hill sector. For example, it can be coupled to the hill sector with screws.
  • As discussed supra, the pole insert preferably has a prismatic geometry along the longitudinal axis over at least 80% of its length, L9, excluding the converging proximal portion 9p, of length L9p. The ridges between the hill upper surface 3U and the hill lateral surfaces are chamfered, then the corresponding ridges of the proximal portion of the recess can be chamfered too.
  • The topography, illustrated in Fig. 6, of the pole insert upper surface 9U and/or first and second lateral surfaces 9L can be machined to form grooves 9gu, 9gl either transverse, or parallel to the longitudinal axis, of the upper surface or of a lateral surface. The grooves may extend along a straight, curved or broken line. Alternatively, holes 9hu, 9hl can be drilled through the surfaces. The holes can be blind holes (i.e., of finite depth) or can be through holes. As explained supra, each hill sector comprises a pole insert for symmetry reasons, the pole inserts are thus machined individually or aligned side by side and all machined together. The resulting aspect of the machined pole insert may differ considerably from its aspect before machining.
  • In conclusion, the present invention offers the advantages that it allows the reduction of the size of the vacuum chamber and a decrease of the overall weight of the cyclotron. Third, the position of the recesses can be precisely manufactured and positioned. Fourth, the magnetic field is deviated inwards by recessed gradient correctors resulting in an inwards shift of the last cycles of the particles path where the magnetic field is more uniform than close to the peripheral edge. It is therefore easier and more predictable to control the properties of the extracted particle beam, and particularly the focusing thereof.
    Ref # Feature
    1 Cyclotron
    2 Magnet pole
    3 Hill sector
    4 Valley sector
    5 Yokes
    6 Flux return yoke
    7 Gap
    8 Recess
    9 Pole insert
    10 Recess
    12 Spiral path
    14 Coils
    3ac Arc of circle
    3ec Chamfered edge
    3L Lateral surface
    3lde Lower distal end of lower lateral edge
    3ll Lower lateral edge
    3lp Lower peripheral line
    3P Peripheral surface
    3U Upper surface
    3uc Upper central edge
    3ude Upper distal end of upper lateral edge
    3ul Upper lateral edge
    3up Upper peripheral edge
    3upc Upper peripheral edge concave portion
    3upe Upper proximal end of upper lateral edge
    4B Bottom surface
    7h Hill gap portion
    7v Valley gap portion
    8ir Recess longitudinal axis
    8rde Recess distal end
    8rpe Recess proximal end
    9dc Pole insert distal end chanfered
    9gl Pole insert groove lateral
    9gu Pole insert groove upper
    9hl Pole insert hole lateral
    9hu Pole insert hole upper
    9L Pole insert lateral surface
    9lp Pole insert proximal portion length
    9p Pole insert proximal portion
    9pe Pole insert proximal edge
    9U Pole insert upper surface
    9pe Pole insert proximal edge
    9s Screw
    9U Pole insert upper surface
    10r1 Recess converging edge (1st)
    10r2 Recess converging edge (2d)
    10rdp Recess distal point
    10rpp Recess proximal point
    Ah Azimuthal length of the upper peripheral edge
    dh Distance upper peripheral edge - highest orbit
    Gh Gap height at hill
    Gv Gap height at valley
    H10 Recess height
    Hh Hill height
    L1, L2 Length of the extraction path comprised within the gap downstream of a point of extraction
    L10 Length between first and second recess distal points
    L101, L102 Length of the recess converging edge
    L8 Recess length
    L9 Pole insert length
    L9p Pole insert length of proximal portion
    Lh Distance between the central axis and a peripheral edge
    MP Median plane
    PE Point of extraction
    Rh Radius of radial pole contour
    Z Central axis
    αh Hill azimuthal angle
    αv Valley azimuthal angle

Claims (15)

  1. A magnet pole (2) for a cyclotron (1) comprising at least 3 hill sectors (3) and a same number of valley sectors (4) comprising a bottom surface (4B), said hill sectors and valley sectors being alternatively distributed around a central axis, Z, each hill sector comprising:
    (a) an upper surface (3U) defined by:
    - an upper peripheral edge (3up), said upper peripheral edge being bounded by a first and a second upper distal ends (3ude), and being defined as the edge of the upper surface located furthest from the central axis;
    - an upper central edge (3uc), said upper central edge being bounded by a first and a second upper proximal ends (3upe) and being defined as the edge of the upper surface located closest from the central axis;
    - a first upper lateral edge (3ul) connecting the first upper distal end and first upper proximal end;
    - a second upper lateral edge (3ul) connecting the second upper distal end and second upper proximal end;
    (b) a first and second lateral surfaces (3L) each extending transversally from the first and second upper lateral edges, to the bottom surfaces of the corresponding valley sectors located on either sides of a hill sector, thus defining a first and second lower lateral edges (311) as the edges intersecting a lateral surface with an adjacent bottom surface, said first and second lower lateral edges each having a lower distal end located furthest from the central axis;
    (c) a peripheral surface (3P) extending from the upper peripheral edge to a lower peripheral line (31p) defined as the segment bounded by the lower distal ends (31de) of the first and second lower lateral edges;
    characterised in that, the upper peripheral edge of at least one hill sector comprises a concave portion with respect to the central axis defining a recess extending at least partially over a portion of the peripheral surface of the corresponding hill sector.
  2. The magnet pole according to claim 1, wherein the recess is generally wedge shaped with a first and second converging lines extending away from the upper peripheral edge, with a converging angle, θ, preferably comprised between 70° and 130°, more preferably between 80°and 110°, most preferably 90°± 5°.
  3. The magnet pole according to claim 2, wherein the recess has a converging portion, away from the upper peripheral edge, said converging portion having one of the following geometry:
    • a sharp corner forming a triangular recess;
    • a straight edge forming a trapezoidal recess; or
    • a rounded edge forming an arched recess.
  4. The magnet pole according to any one of the previous claims, wherein the upper peripheral edge has an azimuthal length, Ah, and wherein the concave portion extends between 3% and 30% of the azimuthal length of the upper peripheral edge, preferably, between 5% and 20%, more preferably, between 8% and 15%.
  5. The magnet pole according to any one of the previous claims, comprising a recess as defined in claim 1 which is separated from the first and second upper lateral edges.
  6. The magnet pole according to any one of the previous claims, comprising a recess as defined in claim 1 which is adjacent to the first upper lateral edge.
  7. The magnet pole according to any one of the previous claims, wherein the recess extends over a portion of the peripheral surface corresponding to a fraction, ξ, of a height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and the lower peripheral line, wherein the fraction, ξ, is comprised between 25% and 75%, preferably between 40% and 60%, most preferably between 45% and 55%.
  8. The magnet pole according to any one of the previous claims, wherein the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
  9. The magnet pole according to any one of the previous claims, wherein the upper peripheral edge is an arc of circle which centre is offset with respect to the central axis, and which radius is not more than 85% of a distance from the central axis to a midpoint of the upper peripheral edge, which is equidistant to the first and second upper distal ends.
  10. The magnet pole according to any one of the previous claims, wherein the number, N, of hill sectors is 3, 4, 5, 6, 7, or 8, preferably N = 4.
  11. Cyclotron for accelerating a particle beam over a given path comprised within a gap, said cyclotron comprising first and second magnet poles according to any one of the previous claims, wherein the first and second magnet poles are positioned symmetrically with respect to a median plane normal to the central axes of the first and second magnet poles forming said gap in between, with hill gap portion being formed between two opposite hill sectors and valley gap portions being formed between two opposite valley sectors.
  12. Cyclotron according to the previous claim, wherein the recess has a first and a second recess distal points, said first and second recess distal points being separated from one another by a distance L10, and wherein the hill gap portion between a pair of hill sectors of the first and second magnet poles has an average height, Gh, and wherein the ratio Gh / L10 is comprised between 5 and 100 %, preferably between 10 and 50 %, more preferably, 20 and 33 %.
  13. Cyclotron according to any one of the claims 11 to 12, comprising a point of extraction, located in a hill gap portion between two opposite upper surfaces of hill sectors of the first and second magnet poles, wherein:
    • the given path of the particle beam is an outward spiral path cycling about the central axis until said first point of extraction whence the particle beam can be driven out of the cyclotron with a given energy along an extraction path,
    • the recess is located downstream from said point of extraction wherein downstream is defined with respect to the direction of the particle beam, such that
    • the extraction path exits the corresponding hill gap portion by intersecting the recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  14. Cyclotron according to claim 13, comprising a second point of extraction in a hill sector defining a second extraction path, and comprising a second recess located downstream from the second point of extraction, such that the second extraction path exits the corresponding hill gap portion by intersecting the second recess with an angle comprised between 80 and 100°, preferably between, 85 and 95°.
  15. Cyclotron according to claim 14, wherein the first and second points of extraction are located on a same hill gap portion.
EP16169494.8A 2016-05-13 2016-05-13 Gradient corrector for cyclotron Active EP3244709B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EP16169494.8A EP3244709B1 (en) 2016-05-13 2016-05-13 Gradient corrector for cyclotron
CA2965016A CA2965016C (en) 2016-05-13 2017-04-25 Gradient corrector for cyclotron
CN201710320606.7A CN107371316B (en) 2016-05-13 2017-05-09 Gradient corrector for cyclotron
CN201720510663.7U CN207201060U (en) 2016-05-13 2017-05-09 Cyclotron and the magnetic pole for cyclotron
JP2017093672A JP6446089B2 (en) 2016-05-13 2017-05-10 Gradient collector for cyclotron
US15/594,534 US10278277B2 (en) 2016-05-13 2017-05-12 Gradient corrector for cyclotron
US15/594,525 US10064264B2 (en) 2016-05-13 2017-05-12 Pole insert for cyclotron
US15/594,527 US9961757B2 (en) 2016-05-13 2017-05-12 Peripheral hill sector design for cyclotron
US15/594,538 US9907153B2 (en) 2016-05-13 2017-05-12 Compact cyclotron

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16169494.8A EP3244709B1 (en) 2016-05-13 2016-05-13 Gradient corrector for cyclotron

Publications (2)

Publication Number Publication Date
EP3244709A1 true EP3244709A1 (en) 2017-11-15
EP3244709B1 EP3244709B1 (en) 2020-01-01

Family

ID=55970881

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16169494.8A Active EP3244709B1 (en) 2016-05-13 2016-05-13 Gradient corrector for cyclotron

Country Status (4)

Country Link
EP (1) EP3244709B1 (en)
JP (1) JP6446089B2 (en)
CN (2) CN107371316B (en)
CA (1) CA2965016C (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113438795A (en) * 2020-03-06 2021-09-24 离子束应用股份有限公司 Synchrocyclotron for extracting beams with different energies
CN116170933A (en) * 2023-01-09 2023-05-26 中国科学院近代物理研究所 Magnetic field device for application type isochronous cyclotron

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3244709B1 (en) * 2016-05-13 2020-01-01 Ion Beam Applications S.A. Gradient corrector for cyclotron
JP6739393B2 (en) * 2017-04-18 2020-08-12 株式会社日立製作所 Particle beam accelerator and particle beam therapy system
CN109362172B (en) * 2018-11-27 2019-09-13 中国原子能科学研究院 A kind of high energy, high current alternating gradient cyclotron

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398308A (en) * 1964-11-19 1968-08-20 Licentia Gmbh Cyclotron device including dummy magnetic components for improved magnetic field symmetry
FR2234733A1 (en) * 1973-06-19 1975-01-17 Ca Atomic Energy Ltd
EP1069809A1 (en) * 1999-07-13 2001-01-17 Ion Beam Applications S.A. Isochronous cyclotron and method of extraction of charged particles from such cyclotron
RU2373673C1 (en) * 2008-06-09 2009-11-20 Федеральное государственное унитарное предприятие "Научно-исследовательский институт электрофизической аппаратуры им. Д.В. Ефремова" Isochronous cyclotron for accelerating several types of charged particles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57159000A (en) * 1981-03-26 1982-09-30 Japan Steel Works Ltd Electromagnet pole for circular charged particle accelerator
JPS6251200A (en) * 1985-08-28 1987-03-05 株式会社日本製鋼所 Magnetic electrode structure of cyclotron having isochronismmagnetic field distribution
JP3456139B2 (en) * 1998-02-23 2003-10-14 三菱電機株式会社 Cyclotron equipment
US8723135B2 (en) * 2012-04-03 2014-05-13 Nissin Ion Equipment Co., Ltd. Ion beam bending magnet for a ribbon-shaped ion beam
EP3244709B1 (en) * 2016-05-13 2020-01-01 Ion Beam Applications S.A. Gradient corrector for cyclotron

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398308A (en) * 1964-11-19 1968-08-20 Licentia Gmbh Cyclotron device including dummy magnetic components for improved magnetic field symmetry
FR2234733A1 (en) * 1973-06-19 1975-01-17 Ca Atomic Energy Ltd
EP1069809A1 (en) * 1999-07-13 2001-01-17 Ion Beam Applications S.A. Isochronous cyclotron and method of extraction of charged particles from such cyclotron
RU2373673C1 (en) * 2008-06-09 2009-11-20 Федеральное государственное унитарное предприятие "Научно-исследовательский институт электрофизической аппаратуры им. Д.В. Ефремова" Isochronous cyclotron for accelerating several types of charged particles

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113438795A (en) * 2020-03-06 2021-09-24 离子束应用股份有限公司 Synchrocyclotron for extracting beams with different energies
CN113438795B (en) * 2020-03-06 2023-04-07 离子束应用股份有限公司 Synchrocyclotron and method for extracting charged particles of different energies
CN116170933A (en) * 2023-01-09 2023-05-26 中国科学院近代物理研究所 Magnetic field device for application type isochronous cyclotron
CN116170933B (en) * 2023-01-09 2023-09-05 中国科学院近代物理研究所 Magnetic field device for application type isochronous cyclotron

Also Published As

Publication number Publication date
CN107371316B (en) 2019-08-27
CN207201060U (en) 2018-04-06
CA2965016C (en) 2019-07-30
JP2017204469A (en) 2017-11-16
CN107371316A (en) 2017-11-21
CA2965016A1 (en) 2017-11-13
EP3244709B1 (en) 2020-01-01
JP6446089B2 (en) 2018-12-26

Similar Documents

Publication Publication Date Title
US10278277B2 (en) Gradient corrector for cyclotron
CA2965016C (en) Gradient corrector for cyclotron
EP3244708B1 (en) Peripheral hill sector design for cyclotron
JP4713799B2 (en) Isochronous sector-focused cyclotron and method for extracting charged particles from the cyclotron
JP6249542B2 (en) Space-saving cyclotron
ES2901895T3 (en) Compact, low-energy, high-frequency linear accelerator design
EP4319493A1 (en) Cyclotron capable of accelerating alpha particles and h2+ particles, and high-gain method and high-precision method
CN110430659B (en) Rectangular waveguide ship-shaped resonant cavity
EP3244707B1 (en) Pole insert for cyclotron
Fujishima et al. Numerical analyses of the injection and extraction trajectories for the RIKEN superconducting ring cyclotron
CN116918460A (en) Circular accelerator and particle beam therapy system

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN PUBLISHED

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20180508

RBV Designated contracting states (corrected)

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20190813

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

Ref country code: AT

Ref legal event code: REF

Ref document number: 1221498

Country of ref document: AT

Kind code of ref document: T

Effective date: 20200115

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602016027157

Country of ref document: DE

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20200101

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200527

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200401

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200401

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200501

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200402

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602016027157

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1221498

Country of ref document: AT

Kind code of ref document: T

Effective date: 20200101

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602016027157

Country of ref document: DE

26N No opposition filed

Effective date: 20201002

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200531

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200531

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20200513

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200513

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200513

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200513

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20201201

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20200101

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230504

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20230525

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20230527

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 20230529

Year of fee payment: 8