EP3227463A4 - Procédés et réactifs pour détecter neisseria gonorrhoeae et ses déterminants de résistance antimicrobienne - Google Patents

Procédés et réactifs pour détecter neisseria gonorrhoeae et ses déterminants de résistance antimicrobienne Download PDF

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Publication number
EP3227463A4
EP3227463A4 EP15865974.8A EP15865974A EP3227463A4 EP 3227463 A4 EP3227463 A4 EP 3227463A4 EP 15865974 A EP15865974 A EP 15865974A EP 3227463 A4 EP3227463 A4 EP 3227463A4
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EP
European Patent Office
Prior art keywords
reagents
methods
neisseria gonorrhoeae
antimicrobial resistance
resistance determinants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15865974.8A
Other languages
German (de)
English (en)
Other versions
EP3227463A1 (fr
Inventor
Jo-Anne R. Dillon
Ali TAHERI
Anthony J. KUSALIK
Rajinder P. S. PARTI
Nurul Huda KHAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Saskatchewan
Original Assignee
University of Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Saskatchewan filed Critical University of Saskatchewan
Publication of EP3227463A1 publication Critical patent/EP3227463A1/fr
Publication of EP3227463A4 publication Critical patent/EP3227463A4/fr
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP15865974.8A 2014-12-05 2015-12-03 Procédés et réactifs pour détecter neisseria gonorrhoeae et ses déterminants de résistance antimicrobienne Withdrawn EP3227463A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462088332P 2014-12-05 2014-12-05
US201562215520P 2015-09-08 2015-09-08
PCT/CA2015/051264 WO2016086305A1 (fr) 2014-12-05 2015-12-03 Procédés et réactifs pour détecter neisseria gonorrhoeae et ses déterminants de résistance antimicrobienne

Publications (2)

Publication Number Publication Date
EP3227463A1 EP3227463A1 (fr) 2017-10-11
EP3227463A4 true EP3227463A4 (fr) 2018-09-05

Family

ID=56090767

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15865974.8A Withdrawn EP3227463A4 (fr) 2014-12-05 2015-12-03 Procédés et réactifs pour détecter neisseria gonorrhoeae et ses déterminants de résistance antimicrobienne

Country Status (6)

Country Link
EP (1) EP3227463A4 (fr)
AU (1) AU2015358251A1 (fr)
BR (1) BR112017011850A2 (fr)
CA (1) CA2969825A1 (fr)
MX (1) MX2017007147A (fr)
WO (1) WO2016086305A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3209803A4 (fr) 2014-10-21 2018-06-13 Ubiome, Inc. Procédé et système de diagnostic et de thérapie fondés sur le microbiome
AU2017295861A1 (en) * 2016-07-13 2019-01-24 Psomagen, Inc. Method and system for microbial pharmacogenomics
CN107058552B (zh) * 2017-05-05 2020-08-14 天津科润农业科技股份有限公司黄瓜研究所 黄瓜雄性不育基因、分子标记、筛选方法及其用途
SG11202102098WA (en) * 2018-09-03 2021-04-29 Visby Medical Inc Devices and methods for antibiotic susceptibility testing
US20220220539A1 (en) * 2019-05-07 2022-07-14 Roche Molecular Systems, Inc. Compositions and methods for detection of neisseria gonorroheae
CN111647671A (zh) * 2019-11-12 2020-09-11 广东美格基因科技有限公司 用于检测淋病奈瑟球菌的荧光定量pcr方法及相应的检测试剂盒
EP4085149A4 (fr) 2020-01-03 2024-03-06 Visby Medical Inc Dispositifs et procédés d'essai de susceptibilité aux antibiotiques
CN111398576B (zh) * 2020-05-15 2023-07-11 西华大学 一种氧氟沙星快速灵敏检测的试剂盒及探针和方法
CN112961805B (zh) * 2020-12-17 2022-05-20 广东省科学院微生物研究所(广东省微生物分析检测中心) 一种喹诺酮类药物耐药基因gyrA和parE同时发生突变的鼠伤寒沙门菌及其应用
CN112831581A (zh) * 2021-02-10 2021-05-25 华东医院 可治愈性传播感染病原体检测体系及其试剂盒和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1847616A2 (fr) * 2006-04-07 2007-10-24 Siemens Medical Solutions Diagnostics Séquences d'oligonucléotides spécifiques à Neisseria gonorrhoeae
US20120071336A1 (en) * 2010-06-02 2012-03-22 Medical Diagnostic Laboratories, Llc Antibiotic resistance profile for Neisseria gonorrhoeae and use of same in diagnosis and treatment of gonorrhea

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532099A (ja) * 2004-04-08 2007-11-15 ザ ステイト オヴ クイーンズランド 淋菌の検出
EP2971083B1 (fr) * 2013-03-15 2018-05-02 Becton, Dickinson and Company Détection de neisseria gonorrhoeae

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1847616A2 (fr) * 2006-04-07 2007-10-24 Siemens Medical Solutions Diagnostics Séquences d'oligonucléotides spécifiques à Neisseria gonorrhoeae
US20120071336A1 (en) * 2010-06-02 2012-03-22 Medical Diagnostic Laboratories, Llc Antibiotic resistance profile for Neisseria gonorrhoeae and use of same in diagnosis and treatment of gonorrhea

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
J. CAMARA ET AL: "Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain", JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY., vol. 67, no. 8, 7 May 2012 (2012-05-07), GB, pages 1858 - 1860, XP055492882, ISSN: 0305-7453, DOI: 10.1093/jac/dks162 *
M. UNEMO ET AL: "Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future", CLINICAL MICROBIOLOGY REVIEWS., vol. 27, no. 3, 30 June 2014 (2014-06-30), US, pages 587 - 613, XP055467264, ISSN: 0893-8512, DOI: 10.1128/CMR.00010-14 *
M.P. MAGOOA ET AL: "Determination of Neisseria gonorrhoeae susceptibility to ciprofloxacin in clinical specimens from men using a real-time PCR assay", INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, vol. 42, no. 1, 1 July 2013 (2013-07-01), AMSTERDAM, NL, pages 63 - 67, XP055467742, ISSN: 0924-8579, DOI: 10.1016/j.ijantimicag.2013.02.026 *
R. LINDBERG ET AL: "Neisseria gonorrhoeae Isolates with Reduced Susceptibility to Cefixime and Ceftriaxone: Association with Genetic Polymorphisms in penA, mtrR, porB1b, and ponA", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 51, no. 6, 9 April 2007 (2007-04-09), US, pages 2117 - 2122, XP055492887, ISSN: 0066-4804, DOI: 10.1128/AAC.01604-06 *
See also references of WO2016086305A1 *
SUMUDU R. PERERA ET AL: "Multiplex Real-Time PCR Assay for Simultaneous Identification of Neisseria gonorrhoeae and its Ciprofloxacin Susceptibility Status", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 55, no. 11, 24 November 2017 (2017-11-24), US, pages 3201 - 3209, XP055467734, ISSN: 0095-1137, DOI: 10.1128/JCM.00855-17 *
THAKUR SIDHARATH D ET AL: "Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally", SEXUALLY TRANSMITTED INFECTIONS, BMJ PUBLISHING GROUP, LONDON, GB, vol. 90, no. 4, 31 May 2014 (2014-05-31), pages 297 - 302, XP009504830, ISSN: 1368-4973, DOI: 10.1136/SEXTRANS-2013-051229 *

Also Published As

Publication number Publication date
EP3227463A1 (fr) 2017-10-11
CA2969825A1 (fr) 2016-06-09
WO2016086305A1 (fr) 2016-06-09
MX2017007147A (es) 2017-09-05
BR112017011850A2 (pt) 2018-02-27
AU2015358251A1 (en) 2017-06-29

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