EP3227318A4 - Compositions d'immunoadhésine dpp4 et procédés - Google Patents

Compositions d'immunoadhésine dpp4 et procédés Download PDF

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Publication number
EP3227318A4
EP3227318A4 EP15866344.3A EP15866344A EP3227318A4 EP 3227318 A4 EP3227318 A4 EP 3227318A4 EP 15866344 A EP15866344 A EP 15866344A EP 3227318 A4 EP3227318 A4 EP 3227318A4
Authority
EP
European Patent Office
Prior art keywords
dpp4
immunoadhesin
compositions
methods
immunoadhesin compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15866344.3A
Other languages
German (de)
English (en)
Other versions
EP3227318A1 (fr
Inventor
Keith Lynn Wycoff
James M. MACLEAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Planet Biotechnology Inc
Original Assignee
Planet Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Planet Biotechnology Inc filed Critical Planet Biotechnology Inc
Publication of EP3227318A1 publication Critical patent/EP3227318A1/fr
Publication of EP3227318A4 publication Critical patent/EP3227318A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14005—Dipeptidyl-peptidase IV (3.4.14.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
EP15866344.3A 2014-12-05 2015-12-05 Compositions d'immunoadhésine dpp4 et procédés Withdrawn EP3227318A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462124011P 2014-12-05 2014-12-05
PCT/US2015/064142 WO2016090345A1 (fr) 2014-12-05 2015-12-05 Compositions d'immunoadhésine dpp4 et procédés

Publications (2)

Publication Number Publication Date
EP3227318A1 EP3227318A1 (fr) 2017-10-11
EP3227318A4 true EP3227318A4 (fr) 2018-12-12

Family

ID=56092581

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15866344.3A Withdrawn EP3227318A4 (fr) 2014-12-05 2015-12-05 Compositions d'immunoadhésine dpp4 et procédés

Country Status (3)

Country Link
EP (1) EP3227318A4 (fr)
CA (1) CA2969891A1 (fr)
WO (1) WO2016090345A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10849972B2 (en) 2018-11-27 2020-12-01 King Adulaziz University Trimeric S1-CD40L fusion protein vaccine against Middle East respiratory syndrome-coronavirus
US11364276B2 (en) 2019-03-26 2022-06-21 National Guard Health Affairs Antiviral peptides for treatment of the middle east respiratory syndrome
CN111592602B (zh) * 2020-02-10 2021-03-02 中国科学院微生物研究所 一种β冠状病毒抗原、其制备方法和应用
CN111781349B (zh) * 2020-04-03 2022-04-22 中国科学院苏州纳米技术与纳米仿生研究所 能够预测covid-19患者预后的诊断试剂盒
CN112043825B (zh) * 2020-07-13 2023-12-05 中国医学科学院医学生物学研究所 一种基于新型冠状病毒突刺蛋白s1区域预防新型冠状病毒感染的亚单位疫苗

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014045254A2 (fr) * 2012-09-23 2014-03-27 Erasmus University Medical Center Rotterdam Lignée c de coronavirus bêta humains et identification de la peptidase dipeptidylique n-terminale en tant que récepteur viral
WO2014134439A1 (fr) * 2013-03-01 2014-09-04 New York Blood Center, Inc. Composition immunogène pour infection de coronavirus de syndrome respiratoire du moyen orient (mers-cov)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224792B1 (es) * 2002-06-28 2007-02-16 Era Plantech, S.L. Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulos endoplasmico en plantas.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014045254A2 (fr) * 2012-09-23 2014-03-27 Erasmus University Medical Center Rotterdam Lignée c de coronavirus bêta humains et identification de la peptidase dipeptidylique n-terminale en tant que récepteur viral
WO2014134439A1 (fr) * 2013-03-01 2014-09-04 New York Blood Center, Inc. Composition immunogène pour infection de coronavirus de syndrome respiratoire du moyen orient (mers-cov)

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JIE CUI ET AL: "Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus", VIROLOGY JOURNAL, BIOMED CENTRAL, LONDON, GB, vol. 10, no. 1, 10 October 2013 (2013-10-10), pages 304, XP021164817, ISSN: 1743-422X, DOI: 10.1186/1743-422X-10-304 *
NIANSHUANG WANG ET AL: "Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4", CELL RESEARCH - XIBAO YANJIU, vol. 23, no. 8, 9 July 2013 (2013-07-09), GB, CN, pages 986 - 993, XP055302109, ISSN: 1001-0602, DOI: 10.1038/cr.2013.92 *
See also references of WO2016090345A1 *
V. S. RAJ ET AL: "Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus", JOURNAL OF VIROLOGY., vol. 88, no. 3, 1 February 2014 (2014-02-01), US, pages 1834 - 1838, XP055483571, ISSN: 0022-538X, DOI: 10.1128/JVI.02935-13 *
V. STALIN RAJ ET AL: "Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC", NATURE, vol. 495, no. 7440, 13 March 2013 (2013-03-13), GB, pages 251 - 254, XP055302115, ISSN: 0028-0836, DOI: 10.1038/nature12005 *
WENFEI SONG ET AL: "Identification of residues on human receptor DPP4 critical for MERS-CoV binding and entry", VIROLOGY, vol. 471-473, 1 December 2014 (2014-12-01), AMSTERDAM, NL, pages 49 - 53, XP055453503, ISSN: 0042-6822, DOI: 10.1016/j.virol.2014.10.006 *

Also Published As

Publication number Publication date
WO2016090345A1 (fr) 2016-06-09
CA2969891A1 (fr) 2016-06-09
EP3227318A1 (fr) 2017-10-11

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