EP3227318A4 - Dpp4 immunoadhesin compositions and methods - Google Patents

Dpp4 immunoadhesin compositions and methods Download PDF

Info

Publication number
EP3227318A4
EP3227318A4 EP15866344.3A EP15866344A EP3227318A4 EP 3227318 A4 EP3227318 A4 EP 3227318A4 EP 15866344 A EP15866344 A EP 15866344A EP 3227318 A4 EP3227318 A4 EP 3227318A4
Authority
EP
European Patent Office
Prior art keywords
dpp4
immunoadhesin
compositions
methods
immunoadhesin compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15866344.3A
Other languages
German (de)
French (fr)
Other versions
EP3227318A1 (en
Inventor
Keith Lynn Wycoff
James M. MACLEAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Planet Biotechnology Inc
Original Assignee
Planet Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Planet Biotechnology Inc filed Critical Planet Biotechnology Inc
Publication of EP3227318A1 publication Critical patent/EP3227318A1/en
Publication of EP3227318A4 publication Critical patent/EP3227318A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14005—Dipeptidyl-peptidase IV (3.4.14.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
EP15866344.3A 2014-12-05 2015-12-05 Dpp4 immunoadhesin compositions and methods Withdrawn EP3227318A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462124011P 2014-12-05 2014-12-05
PCT/US2015/064142 WO2016090345A1 (en) 2014-12-05 2015-12-05 Dpp4 immunoadhesin compositions and methods

Publications (2)

Publication Number Publication Date
EP3227318A1 EP3227318A1 (en) 2017-10-11
EP3227318A4 true EP3227318A4 (en) 2018-12-12

Family

ID=56092581

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15866344.3A Withdrawn EP3227318A4 (en) 2014-12-05 2015-12-05 Dpp4 immunoadhesin compositions and methods

Country Status (3)

Country Link
EP (1) EP3227318A4 (en)
CA (1) CA2969891A1 (en)
WO (1) WO2016090345A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10849972B2 (en) 2018-11-27 2020-12-01 King Adulaziz University Trimeric S1-CD40L fusion protein vaccine against Middle East respiratory syndrome-coronavirus
US11364276B2 (en) 2019-03-26 2022-06-21 National Guard Health Affairs Antiviral peptides for treatment of the middle east respiratory syndrome
WO2021159648A1 (en) * 2020-02-10 2021-08-19 中国科学院微生物研究所 Beta-coronavirus antigen, preparation method therefor and use thereof
CN111781349B (en) * 2020-04-03 2022-04-22 中国科学院苏州纳米技术与纳米仿生研究所 Diagnostic kit capable of predicting prognosis of COVID-19 patient
CN112043825B (en) * 2020-07-13 2023-12-05 中国医学科学院医学生物学研究所 Subunit vaccine for preventing novel coronavirus infection based on novel coronavirus spike protein S1 region

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014045254A2 (en) * 2012-09-23 2014-03-27 Erasmus University Medical Center Rotterdam Human betacoronavirus lineage c and identification of n-terminal dipeptidyl peptidase as its virus receptor
WO2014134439A1 (en) * 2013-03-01 2014-09-04 New York Blood Center, Inc. Immunogenic composition for mers coronavirus infection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224792B1 (en) * 2002-06-28 2007-02-16 Era Plantech, S.L. PRODUCTION OF PEPTIDES AND PROTEINS BY ACCUMULATION OF PROTEIN BODIES DERIVED FROM ENDOPLASMIC RETICLES IN PLANTS.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014045254A2 (en) * 2012-09-23 2014-03-27 Erasmus University Medical Center Rotterdam Human betacoronavirus lineage c and identification of n-terminal dipeptidyl peptidase as its virus receptor
WO2014134439A1 (en) * 2013-03-01 2014-09-04 New York Blood Center, Inc. Immunogenic composition for mers coronavirus infection

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JIE CUI ET AL: "Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus", VIROLOGY JOURNAL, BIOMED CENTRAL, LONDON, GB, vol. 10, no. 1, 10 October 2013 (2013-10-10), pages 304, XP021164817, ISSN: 1743-422X, DOI: 10.1186/1743-422X-10-304 *
NIANSHUANG WANG ET AL: "Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4", CELL RESEARCH - XIBAO YANJIU, vol. 23, no. 8, 9 July 2013 (2013-07-09), GB, CN, pages 986 - 993, XP055302109, ISSN: 1001-0602, DOI: 10.1038/cr.2013.92 *
See also references of WO2016090345A1 *
V. S. RAJ ET AL: "Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus", JOURNAL OF VIROLOGY., vol. 88, no. 3, 1 February 2014 (2014-02-01), US, pages 1834 - 1838, XP055483571, ISSN: 0022-538X, DOI: 10.1128/JVI.02935-13 *
V. STALIN RAJ ET AL: "Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC", NATURE, vol. 495, no. 7440, 13 March 2013 (2013-03-13), GB, pages 251 - 254, XP055302115, ISSN: 0028-0836, DOI: 10.1038/nature12005 *
WENFEI SONG ET AL: "Identification of residues on human receptor DPP4 critical for MERS-CoV binding and entry", VIROLOGY, vol. 471-473, 1 December 2014 (2014-12-01), AMSTERDAM, NL, pages 49 - 53, XP055453503, ISSN: 0042-6822, DOI: 10.1016/j.virol.2014.10.006 *

Also Published As

Publication number Publication date
WO2016090345A1 (en) 2016-06-09
CA2969891A1 (en) 2016-06-09
EP3227318A1 (en) 2017-10-11

Similar Documents

Publication Publication Date Title
EP3523437A4 (en) Oligonucleotide compositions and methods thereof
EP3324978A4 (en) Oligonucleotide compositions and methods thereof
EP3212225A4 (en) Methods and compositions for modified t cells
EP3132025A4 (en) Methods and compositions for modifying genomic dna
EP3190894A4 (en) Microbial compositions and methods
EP3152319A4 (en) Methods and compositions for nuclease design
EP3183349A4 (en) Methods for preparing rebaudioside i and uses
EP3161124A4 (en) Endophytes, associated compositions, and methods of use thereof
EP3110945A4 (en) Compositions and methods for site directed genomic modification
EP3102670A4 (en) Systems, methods, and compositions relating to combiomics
EP3140305A4 (en) Novel compositions, uses and methods for making them
EP3040326A4 (en) Halo-olefin composition
EP3145312A4 (en) Pesticidal compositions and related methods
EP3155399A4 (en) Viscometer and methods for using the same
EP3179983A4 (en) Anti-methanogenic compositions and uses thereof
IL246879A0 (en) Apilimod compositions and methods for using same
EP3253389A4 (en) Apilimod compositions and methods for using same
EP3194044A4 (en) Extractor and related methods
EP3198275A4 (en) Sterilization compositions and methods
EP3148564A4 (en) Methods and compositions for immunomodulation
EP3093296A4 (en) Fuc3s4s substituted oligoglycosaminoglycan and preparation method thereof
EP3183364A4 (en) Rna amplification methods
EP3139741A4 (en) Methods and compositions comprising 10-hydroxy-2-decenoic acid
EP3137624A4 (en) Compositions and methods for modulating mtorc1
EP3227318A4 (en) Dpp4 immunoadhesin compositions and methods

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20170608

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/14 20060101ALI20180731BHEP

Ipc: A61K 39/215 20060101ALI20180731BHEP

Ipc: A61K 39/42 20060101ALI20180731BHEP

Ipc: C12N 9/48 20060101ALI20180731BHEP

Ipc: C07K 14/165 20060101ALI20180731BHEP

Ipc: C12N 15/63 20060101ALI20180731BHEP

Ipc: C07K 14/47 20060101AFI20180731BHEP

Ipc: A61K 38/00 20060101ALI20180731BHEP

Ipc: A61K 39/12 20060101ALI20180731BHEP

Ipc: C07K 19/00 20060101ALI20180731BHEP

Ipc: C12P 21/02 20060101ALI20180731BHEP

Ipc: C07K 16/10 20060101ALI20180731BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20181112

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 38/00 20060101ALI20181106BHEP

Ipc: A61K 39/42 20060101ALI20181106BHEP

Ipc: C12N 9/48 20060101ALI20181106BHEP

Ipc: C12N 15/63 20060101ALI20181106BHEP

Ipc: C07K 14/47 20060101AFI20181106BHEP

Ipc: A61K 39/12 20060101ALI20181106BHEP

Ipc: A61K 31/14 20060101ALI20181106BHEP

Ipc: A61K 39/215 20060101ALI20181106BHEP

Ipc: C07K 19/00 20060101ALI20181106BHEP

Ipc: C07K 16/10 20060101ALI20181106BHEP

Ipc: C12P 21/02 20060101ALI20181106BHEP

Ipc: C07K 14/165 20060101ALI20181106BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20191024

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20210913

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

INTC Intention to grant announced (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20220721