EP3226885A4 - Produits intermédiaires et procédés de préparation de micafungine - Google Patents

Produits intermédiaires et procédés de préparation de micafungine Download PDF

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Publication number
EP3226885A4
EP3226885A4 EP15849490.6A EP15849490A EP3226885A4 EP 3226885 A4 EP3226885 A4 EP 3226885A4 EP 15849490 A EP15849490 A EP 15849490A EP 3226885 A4 EP3226885 A4 EP 3226885A4
Authority
EP
European Patent Office
Prior art keywords
micafungin
intermediates
prepare
processes
prepare micafungin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15849490.6A
Other languages
German (de)
English (en)
Other versions
EP3226885A2 (fr
Inventor
Anand Vijaykumar MANTRI
Kumar HUCHANNA Yogish
Talluri Bhushaiah CHOWDARY
Gaurav Kulkarni
Ganga Ramu VASANTHAKUMAR
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3226885A2 publication Critical patent/EP3226885A2/fr
Publication of EP3226885A4 publication Critical patent/EP3226885A4/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
EP15849490.6A 2014-10-07 2015-10-07 Produits intermédiaires et procédés de préparation de micafungine Withdrawn EP3226885A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3174MU2014 2014-10-07
PCT/IN2015/000379 WO2016056023A2 (fr) 2014-10-07 2015-10-07 Produits intermédiaires et procédés de préparation de micafungine

Publications (2)

Publication Number Publication Date
EP3226885A2 EP3226885A2 (fr) 2017-10-11
EP3226885A4 true EP3226885A4 (fr) 2018-07-18

Family

ID=55653918

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15849490.6A Withdrawn EP3226885A4 (fr) 2014-10-07 2015-10-07 Produits intermédiaires et procédés de préparation de micafungine

Country Status (2)

Country Link
EP (1) EP3226885A4 (fr)
WO (1) WO2016056023A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106866650A (zh) * 2017-01-09 2017-06-20 博瑞生物医药泰兴市有限公司 一种米卡芬净的合成与提纯方法
WO2019138299A1 (fr) * 2018-01-09 2019-07-18 Aurozymes Procédé amélioré pour la préparation de micafungine sodique
CN113087775B (zh) * 2018-05-31 2022-07-08 杭州中美华东制药有限公司 米卡芬净钠新晶型ii及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013034670A1 (fr) * 2011-09-09 2013-03-14 Sandoz Ag Préparation d'intermédiaires de la micafungine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107458A (en) * 1994-10-07 2000-08-22 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides having antibiotic activity
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
JP4784093B2 (ja) * 2002-08-08 2011-09-28 アステラス製薬株式会社 イソオキサゾリル安息香酸の製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013034670A1 (fr) * 2011-09-09 2013-03-14 Sandoz Ag Préparation d'intermédiaires de la micafungine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZBIGNIEW J. KAMINSKI: "Triazine-based condensing reagents", BIOPOLYMERS, vol. 55, no. 2, 1 January 2000 (2000-01-01), US, pages 140 - 164, XP055481702, ISSN: 0006-3525, DOI: 10.1002/1097-0282(2000)55:2<140::AID-BIP40>3.0.CO;2-B *

Also Published As

Publication number Publication date
WO2016056023A3 (fr) 2016-07-07
WO2016056023A2 (fr) 2016-04-14
EP3226885A2 (fr) 2017-10-11

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20170814

AK Designated contracting states

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
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A4 Supplementary search report drawn up and despatched

Effective date: 20180619

RIC1 Information provided on ipc code assigned before grant

Ipc: C07D 261/08 20060101AFI20180613BHEP

Ipc: C07D 413/12 20060101ALI20180613BHEP

Ipc: A61K 38/12 20060101ALI20180613BHEP

17Q First examination report despatched

Effective date: 20190924

STAA Information on the status of an ep patent application or granted ep patent

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Effective date: 20200205