EP3213055A4 - Determination of water treatment parameters based on absorbance and fluorescence - Google Patents

Determination of water treatment parameters based on absorbance and fluorescence Download PDF

Info

Publication number
EP3213055A4
EP3213055A4 EP15854992.3A EP15854992A EP3213055A4 EP 3213055 A4 EP3213055 A4 EP 3213055A4 EP 15854992 A EP15854992 A EP 15854992A EP 3213055 A4 EP3213055 A4 EP 3213055A4
Authority
EP
European Patent Office
Prior art keywords
absorbance
fluorescence
determination
water treatment
parameters based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15854992.3A
Other languages
German (de)
French (fr)
Other versions
EP3213055B1 (en
EP3213055A1 (en
Inventor
Adam Matthew GILMORE
Kiichiro TOMIOKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Horiba Advanced Techno Co Ltd
Horiba Instruments Inc
Original Assignee
Horiba Advanced Techno Co Ltd
Horiba Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horiba Advanced Techno Co Ltd, Horiba Instruments Inc filed Critical Horiba Advanced Techno Co Ltd
Publication of EP3213055A1 publication Critical patent/EP3213055A1/en
Publication of EP3213055A4 publication Critical patent/EP3213055A4/en
Application granted granted Critical
Publication of EP3213055B1 publication Critical patent/EP3213055B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3155Measuring in two spectral ranges, e.g. UV and visible
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N2021/8411Application to online plant, process monitoring
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/061Sources
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18Water

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
EP15854992.3A 2014-10-29 2015-10-15 Determination of water treatment parameters based on absorbance and fluorescence Active EP3213055B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/527,753 US10184892B2 (en) 2014-10-29 2014-10-29 Determination of water treatment parameters based on absorbance and fluorescence
PCT/US2015/055726 WO2016069279A1 (en) 2014-10-29 2015-10-15 Determination of water treatment parameters based on absorbance and fluorescence

Publications (3)

Publication Number Publication Date
EP3213055A1 EP3213055A1 (en) 2017-09-06
EP3213055A4 true EP3213055A4 (en) 2018-12-05
EP3213055B1 EP3213055B1 (en) 2020-12-02

Family

ID=55852375

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15854992.3A Active EP3213055B1 (en) 2014-10-29 2015-10-15 Determination of water treatment parameters based on absorbance and fluorescence

Country Status (6)

Country Link
US (1) US10184892B2 (en)
EP (1) EP3213055B1 (en)
JP (1) JP6643333B2 (en)
CN (1) CN107209112B (en)
SG (1) SG11201703259UA (en)
WO (1) WO2016069279A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9670072B2 (en) 2014-10-29 2017-06-06 Horiba Instruments Incorporated Determination of water treatment parameters based on absorbance and fluorescence
US10184892B2 (en) * 2014-10-29 2019-01-22 Horiba Instruments Incorporated Determination of water treatment parameters based on absorbance and fluorescence
WO2016205944A1 (en) * 2015-06-23 2016-12-29 Trojan Technologies Process and device for the treatment of a fluid containing a contaminant
WO2017023925A1 (en) * 2015-08-03 2017-02-09 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
US11656180B2 (en) 2015-08-03 2023-05-23 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
SE539770C2 (en) * 2016-06-10 2017-11-21 Bomill Ab A detector system comprising a plurality of light guides anda spectrometer comprising the detector system
US20190265164A1 (en) * 2016-11-03 2019-08-29 British American Tobacco (Investments) Limited A method for determining the level of a polycyclic compound of interest present on the surface of a tobacco leaf
WO2018098260A1 (en) * 2016-11-23 2018-05-31 Ysi, Inc. Dual function fluorometer-absorbance sensor
CN106596436B (en) * 2016-12-30 2023-04-11 中国科学院西安光学精密机械研究所 Multi-parameter water quality real-time online monitoring device based on spectrum method
CN107941719B (en) * 2017-11-26 2023-08-18 桂林电子科技大学 Solution surface reflection absorbance measuring device and application thereof
CN108303555B (en) * 2017-12-26 2019-12-20 中国农业大学 Device and method for instantly detecting lead, cadmium and mercury in aquaculture water
CN108226116A (en) * 2017-12-30 2018-06-29 北方工业大学 Intelligent sensor for chlorophyll parameter detection based on interference compensation
WO2019169295A1 (en) 2018-03-02 2019-09-06 Ecolab Usa Inc. Ultralow range fluorometer calibration
JP7074507B2 (en) * 2018-03-06 2022-05-24 オルガノ株式会社 Pollution risk assessment method for water treatment system
US12092568B2 (en) * 2018-04-23 2024-09-17 Meon Medical Solutions Gmbh & Co Kg Optical measuring unit and optical measuring method for obtaining measurement signals of fluid media
WO2020005823A1 (en) * 2018-06-28 2020-01-02 Becton, Dickinson And Company Systems and methods for normalizing signals in blood culture measurement systems
US11906426B2 (en) * 2018-06-29 2024-02-20 Hach Company Suspended solids measurement of wastewater
WO2020031448A1 (en) * 2018-08-10 2020-02-13 日本たばこ産業株式会社 Method for creating reference for determining classification of plant-derived material containing chlorophyll and at least one of polyphenols and terpenoids, program, and device
JP2020034545A (en) * 2018-08-28 2020-03-05 パナソニックIpマネジメント株式会社 Component analysis device and component analysis method
EP3897929A1 (en) 2018-12-21 2021-10-27 Ecolab USA Inc. Quick tracer injection for monitoring osmosis membrane integrity
CN109738393B (en) * 2019-01-10 2021-03-05 上海奥普生物医药股份有限公司 Optical detection device and specific protein analyzer
WO2020186078A1 (en) * 2019-03-12 2020-09-17 Hattingh Paul Testing method for residual organic compounds in a liquid sample
AU2021275061B2 (en) * 2020-05-20 2023-01-19 Ysi, Inc. Spatial gradient-based fluorometer
CN111650141B (en) * 2020-07-06 2021-06-22 湖南大学 Water quality monitoring method, apparatus and system based on multi-wavelength absorbance
CN112683861B (en) * 2020-11-23 2023-04-11 郑州大学 Application of short-wave fluorescence internal filtering technology in cysteine detection
IL281018B (en) * 2021-02-22 2022-01-01 Maytronics Ltd Systems, subsystems and methods for measuring water characteristics in a water facility
CN113720803A (en) * 2021-07-15 2021-11-30 常州罗盘星检测科技有限公司 Method and system for online simultaneous detection of low-concentration and high-concentration floating water at low temperature and high temperature
SE545520C2 (en) * 2022-02-23 2023-10-10 Chalmers Ventures Ab Method and system for determining at least one of the character, composition and reactivity of dissolved organic matter in water

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917406A (en) * 1974-09-16 1975-11-04 Perkin Elmer Corp Optical beam splitter
WO1996014569A2 (en) * 1994-11-05 1996-05-17 Cognitive Solutions Ltd. Detector for chemical analysis
US20020104787A1 (en) * 2000-11-30 2002-08-08 Seiichi Murayama Water treatment control system using fluorescence analyzer
CN101275905A (en) * 2008-04-18 2008-10-01 浙江大学 Multi-source optical spectrum syncretizing portable water quality analysis meter
US20130020480A1 (en) * 2009-11-06 2013-01-24 Ford Jess V Multi-channel source assembly for downhole spectroscopy
CN103630523A (en) * 2012-08-21 2014-03-12 杭州希玛诺光电技术有限公司 Laser induction spectrum generating device used for water quality optical analyzer

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666362A (en) 1970-12-22 1972-05-30 Johnson Research Foundation Me Dual wavelength spectrophotometry
DE2651086B2 (en) 1976-11-09 1978-11-09 Hewlett-Packard Gmbh, 7030 Boeblingen Photometer
US4305660A (en) 1980-06-27 1981-12-15 Farrand Optical Co., Inc. Recording transmission and emission spectra
US4475813A (en) 1982-08-30 1984-10-09 Milton Roy Company Divergent light optical systems for liquid chromatography
US4867559A (en) 1988-01-06 1989-09-19 Amoco Corporation Liquid/liquid fiber-optic fluorescence detector and absorbance analyzer
US4927265A (en) 1988-04-29 1990-05-22 501 Microphoretic Systems, Inc. Detector for fluorescence and absorption spectroscopy
US5285254A (en) 1991-03-25 1994-02-08 Richard J De Sa Rapid-scanning monochromator with moving intermediate slit
JPH05240774A (en) 1992-03-02 1993-09-17 Hitachi Ltd Optical cell and optical detecting device and sample separating/detecting device using them
DE69323060T2 (en) 1993-03-18 1999-06-10 Novartis Ag, Basel Optical detector device for the chemical analysis of small fluid sample volumes
JP3602661B2 (en) * 1996-08-08 2004-12-15 株式会社東芝 Ozone injection device control system
DE19817738C2 (en) * 1998-04-21 2003-02-06 Karl-Friedrich Klein Hollow optical waveguide for trace analysis in aqueous solutions
US6236456B1 (en) 1998-08-18 2001-05-22 Molecular Devices Corporation Optical system for a scanning fluorometer
US6496260B1 (en) * 1998-12-23 2002-12-17 Molecular Devices Corp. Vertical-beam photometer for determination of light absorption pathlength
CN1357104A (en) 1999-04-21 2002-07-03 克罗马根公司 Scanning spectrophotometer for high throughput fluorescence detection
JP3842492B2 (en) * 1999-09-13 2006-11-08 株式会社東芝 Algae concentration measurement system
US20040011965A1 (en) * 2000-08-18 2004-01-22 Hodgkinson Elizabeth Jane Method and apparatus for detecting chemical contamination
JP2002340787A (en) 2001-05-18 2002-11-27 Fuji Electric Co Ltd Apparatus for measuring absorbance
US6995841B2 (en) * 2001-08-28 2006-02-07 Rice University Pulsed-multiline excitation for color-blind fluorescence detection
US7265827B2 (en) 2001-09-07 2007-09-04 Horiba Jobin Yvon, Inc. Double grating three dimensional spectrograph with multi-directional diffraction
US6836332B2 (en) 2001-09-25 2004-12-28 Tennessee Scientific, Inc. Instrument and method for testing fluid characteristics
US7507579B2 (en) * 2002-05-01 2009-03-24 Massachusetts Institute Of Technology Apparatus and methods for simultaneous operation of miniaturized reactors
GB0216934D0 (en) 2002-07-20 2002-08-28 Council Cent Lab Res Councils Optical apparatus
JP2004354068A (en) * 2003-05-27 2004-12-16 Hitachi Ltd Chemical substance measuring instrument using light waveguide
EP1751523B1 (en) 2004-05-13 2017-10-04 NarTest AS A portable device and method for on-site detection and quantification of drugs
US6970241B1 (en) 2004-08-24 2005-11-29 Desa Richard J Device for enabling slow and direct measurement of fluorescence polarization
US7209223B1 (en) 2004-11-15 2007-04-24 Luna Innovations Incorporated Optical device for measuring optical properties of a sample and method relating thereto
US7324202B2 (en) 2004-12-07 2008-01-29 Novx Systems Inc. Optical system
US7569839B2 (en) 2005-04-25 2009-08-04 Jobin Yvon, Inc. Method for classification of carbon nanotubes and other materials
US20070037135A1 (en) 2005-08-08 2007-02-15 Barnes Russell H System and method for the identification and quantification of a biological sample suspended in a liquid
US20070121196A1 (en) * 2005-09-29 2007-05-31 The General Hospital Corporation Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions
US8119066B2 (en) * 2006-02-08 2012-02-21 Molecular Devices, Llc Multimode reader
US7846391B2 (en) * 2006-05-22 2010-12-07 Lumencor, Inc. Bioanalytical instrumentation using a light source subsystem
WO2007143047A1 (en) * 2006-06-01 2007-12-13 Ecolab Inc. Uv fluorometric sensor and method for using the same
US9557217B2 (en) * 2007-02-13 2017-01-31 Bti Holdings, Inc. Universal multidetection system for microplates
US20080272312A1 (en) 2007-05-04 2008-11-06 Chemimage Corporation Hyperspectral fluorescence and absorption bioimaging
FI20085062A0 (en) 2008-01-25 2008-01-25 Wallac Oy Improved measurement system and method
GB0901658D0 (en) 2009-02-03 2009-03-11 Johnson Matthey Plc Methods of measuring fluorescence in liquids
US9645010B2 (en) * 2009-03-10 2017-05-09 The Regents Of The University Of California Fluidic flow cytometry devices and methods
FR2971337B1 (en) * 2011-02-04 2013-03-01 Horiba Abx Sas DEVICE AND METHOD FOR MULTIPARAMETRIC MEASUREMENTS OF MICROPARTICLES IN A FLUID
US8981314B2 (en) * 2011-02-10 2015-03-17 Zaps Technologies, Inc Method and apparatus for the optical determination of total organic carbon in aqueous streams
US8901513B2 (en) * 2011-03-08 2014-12-02 Horiba Instruments, Incorporated System and method for fluorescence and absorbance analysis
JP5618874B2 (en) * 2011-03-15 2014-11-05 株式会社東芝 Fouling generation prediction method and membrane filtration system
US9347882B2 (en) * 2011-06-22 2016-05-24 Molecular Devices, Llc Dynamic signal extension in optical detection systems
FR2999288B1 (en) 2012-12-11 2016-01-08 Envolure MICROPLATE READER DEVICE
US9188527B2 (en) * 2013-01-09 2015-11-17 Molecular Devices, Llc Monochromator-based and filter-based detection system
US20150041682A1 (en) * 2013-08-10 2015-02-12 Benchmark Instrumentation & Analytical Services Inc. Systems and Methods for Monitoring Phenanthrene Equivalent Concentrations
KR102240166B1 (en) * 2013-11-17 2021-04-14 퀀텀-에스아이 인코포레이티드 Integrated device with external light source for probing detecting and analyzing molecules
US9670072B2 (en) * 2014-10-29 2017-06-06 Horiba Instruments Incorporated Determination of water treatment parameters based on absorbance and fluorescence
US10184892B2 (en) * 2014-10-29 2019-01-22 Horiba Instruments Incorporated Determination of water treatment parameters based on absorbance and fluorescence

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917406A (en) * 1974-09-16 1975-11-04 Perkin Elmer Corp Optical beam splitter
WO1996014569A2 (en) * 1994-11-05 1996-05-17 Cognitive Solutions Ltd. Detector for chemical analysis
US20020104787A1 (en) * 2000-11-30 2002-08-08 Seiichi Murayama Water treatment control system using fluorescence analyzer
CN101275905A (en) * 2008-04-18 2008-10-01 浙江大学 Multi-source optical spectrum syncretizing portable water quality analysis meter
US20130020480A1 (en) * 2009-11-06 2013-01-24 Ford Jess V Multi-channel source assembly for downhole spectroscopy
CN103630523A (en) * 2012-08-21 2014-03-12 杭州希玛诺光电技术有限公司 Laser induction spectrum generating device used for water quality optical analyzer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GUO W ET AL: "Characterization of dissolved organic matter in urban sewage using excitation emission matrix fluorescence spectroscopy and parallel factor analysis", JOURNAL OF ENVIRONMENTAL SCIENCES, ELSEVIER BV, NL, vol. 22, no. 11, 2010, pages 1728 - 1734, XP027493317, ISSN: 1001-0742, [retrieved on 20101101], DOI: 10.1016/S1001-0742(09)60312-0 *
HUR J AND CHO J: "Prediction of BOD, COD, and Total Nitrogen Concentrations in a Typical Urban River Using a Fluorescence Excitation-Emission Matrix with PARAFAC and UV Absorption Indices", SENSORS, vol. 12, no. 12, 16 January 2012 (2012-01-16), pages 972 - 986, XP055454328, DOI: 10.3390/s120100972 *
RUIXIA R ET AL: "Use of three-dimensional excitation and emission matrix fluorescence spectroscopy for predicting the disinfection by-product formation potential of reclaimed water", WATER RESEARCH, vol. 46, no. 17, 14 August 2012 (2012-08-14), pages 5765 - 5776, XP028936941, ISSN: 0043-1354, DOI: 10.1016/J.WATRES.2012.08.007 *
See also references of WO2016069279A1 *
YAPPERT M C ET AL: "Design and evaluation of a dual multichannel detector spectrometer for simultaneous molecular absorption and luminescence measurements", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 61, no. 6, 15 March 1989 (1989-03-15), pages 593 - 600, XP000032382, ISSN: 0003-2700, DOI: 10.1021/AC00181A020 *

Also Published As

Publication number Publication date
JP2017536542A (en) 2017-12-07
CN107209112B (en) 2020-08-07
EP3213055B1 (en) 2020-12-02
US10184892B2 (en) 2019-01-22
JP6643333B2 (en) 2020-02-12
CN107209112A (en) 2017-09-26
US20160123882A1 (en) 2016-05-05
WO2016069279A1 (en) 2016-05-06
EP3213055A1 (en) 2017-09-06
SG11201703259UA (en) 2017-05-30

Similar Documents

Publication Publication Date Title
EP3213054A4 (en) Determination of water treatment parameters based on absorbance and fluorescence
EP3213055A4 (en) Determination of water treatment parameters based on absorbance and fluorescence
EP3253387A4 (en) Compounds and uses in treatment of senescence-associated conditons
EP3160498A4 (en) Il-15-based molecules and methods of use thereof
EP3233089A4 (en) Method of treating cancer with cgamp or cgasmp
EP3218005A4 (en) Glycan-interacting compounds and methods of use
EP3157528A4 (en) Oxysterols and methods of use thereof
EP3212192A4 (en) Detection and treatment of excessive hair shedding
EP3234116A4 (en) Methods of treating tissue calcification
EP3240762A4 (en) Treating water
EP3117892A4 (en) Water treatment apparatus
EP3265476A4 (en) Protoxin-ii variants and methods of use
EP2905262B8 (en) Assembly and method for treatment of raw water
EP3180292A4 (en) Water treatment system and method
EP3209613A4 (en) Water treatment system and method
EP3277304A4 (en) Protoxin-ii variants and methods of use
EP3186394A4 (en) Treatment and detection of melanoma
EP3134108A4 (en) Agents and methods of treatment
EP3110902A4 (en) Well treatment methods and fluids
EP3093055A4 (en) Water treatment device and water treatment method
HK1249866A1 (en) Methods of treatment with taselisib
EP3119199A4 (en) Compounds and their methods of use
EP3191411A4 (en) Measurement and treatment of fluid streams
EP3192577A4 (en) Water treatment apparatus and water treatment method
EP3191413A4 (en) Uses of melanin in water

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20170427

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/18 20060101ALI20180223BHEP

Ipc: G01N 21/64 20060101AFI20180223BHEP

Ipc: G01N 21/85 20060101ALI20180223BHEP

Ipc: G01N 21/84 20060101ALN20180223BHEP

Ipc: G01N 21/31 20060101ALI20180223BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20181029

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/18 20060101ALI20181023BHEP

Ipc: G01N 21/85 20060101ALI20181023BHEP

Ipc: G01N 21/84 20060101ALN20181023BHEP

Ipc: G01N 21/64 20060101AFI20181023BHEP

Ipc: G01N 21/31 20060101ALI20181023BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20191010

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/18 20060101ALN20200714BHEP

Ipc: G01N 21/84 20060101ALN20200714BHEP

Ipc: G01N 21/31 20060101ALI20200714BHEP

Ipc: G01N 21/85 20060101ALI20200714BHEP

Ipc: G01N 21/64 20060101AFI20200714BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/18 20060101ALN20200728BHEP

Ipc: G01N 21/84 20060101ALN20200728BHEP

Ipc: G01N 21/31 20060101ALI20200728BHEP

Ipc: G01N 21/64 20060101AFI20200728BHEP

Ipc: G01N 21/85 20060101ALI20200728BHEP

INTG Intention to grant announced

Effective date: 20200821

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1341460

Country of ref document: AT

Kind code of ref document: T

Effective date: 20201215

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602015063055

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210303

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210302

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20201202

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1341460

Country of ref document: AT

Kind code of ref document: T

Effective date: 20201202

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210302

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210405

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602015063055

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210402

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

26N No opposition filed

Effective date: 20210903

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210402

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20211031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211015

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211031

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211031

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20151015

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230530

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20231027

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20231023

Year of fee payment: 9

Ref country code: FR

Payment date: 20231025

Year of fee payment: 9

Ref country code: DE

Payment date: 20231027

Year of fee payment: 9

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201202