EP3164710A4 - Caractérisation biologique d'un produit médicamenteux à l'acétate de glatiramère, à l'aide de cellules humaines et de mammifères - Google Patents

Caractérisation biologique d'un produit médicamenteux à l'acétate de glatiramère, à l'aide de cellules humaines et de mammifères Download PDF

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Publication number
EP3164710A4
EP3164710A4 EP15814349.5A EP15814349A EP3164710A4 EP 3164710 A4 EP3164710 A4 EP 3164710A4 EP 15814349 A EP15814349 A EP 15814349A EP 3164710 A4 EP3164710 A4 EP 3164710A4
Authority
EP
European Patent Office
Prior art keywords
mammalian
human cells
drug product
glatiramer acetate
related drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15814349.5A
Other languages
German (de)
English (en)
Other versions
EP3164710A2 (fr
Inventor
Michael Hayden
Fadi George TOWFIC
Sarah Elisabeth Kolitz
Benjamin James ZESKIND
David Ladkani
Tal Hasson
Liat Hayardeny
Iris Grossman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of EP3164710A2 publication Critical patent/EP3164710A2/fr
Publication of EP3164710A4 publication Critical patent/EP3164710A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP15814349.5A 2014-07-01 2015-07-01 Caractérisation biologique d'un produit médicamenteux à l'acétate de glatiramère, à l'aide de cellules humaines et de mammifères Withdrawn EP3164710A4 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201462019857P 2014-07-01 2014-07-01
US201462020358P 2014-07-02 2014-07-02
US201462025953P 2014-07-17 2014-07-17
US201462047437P 2014-09-08 2014-09-08
US201462078369P 2014-11-11 2014-11-11
US201562134245P 2015-03-17 2015-03-17
US201562162308P 2015-05-15 2015-05-15
PCT/US2015/038901 WO2016004250A2 (fr) 2014-07-01 2015-07-01 Caractérisation biologique d'un produit médicamenteux à l'acétate de glatiramère, à l'aide de cellules humaines et de mammifères

Publications (2)

Publication Number Publication Date
EP3164710A2 EP3164710A2 (fr) 2017-05-10
EP3164710A4 true EP3164710A4 (fr) 2018-04-11

Family

ID=55020098

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15814349.5A Withdrawn EP3164710A4 (fr) 2014-07-01 2015-07-01 Caractérisation biologique d'un produit médicamenteux à l'acétate de glatiramère, à l'aide de cellules humaines et de mammifères

Country Status (6)

Country Link
EP (1) EP3164710A4 (fr)
CA (1) CA2952849A1 (fr)
IL (1) IL249686A0 (fr)
TW (1) TW201610169A (fr)
UY (1) UY36197A (fr)
WO (1) WO2016004250A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018053109A1 (fr) * 2016-09-14 2018-03-22 Teva Pharmaceutical Industries Ltd. Caractérisation d'expression génique d'un produit médicamenteux associé à l'acétate de glatiramère dans des cellules humaines et de mammifères
CN116637123B (zh) * 2023-06-07 2024-02-13 上海市东方医院（同济大学附属东方医院） 敲降或下调C15orf39基因表达的试剂在制备治疗胃癌的药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2477232T5 (es) * 2007-06-21 2017-11-23 Momenta Pharmaceuticals, Inc. Análisis de copolímeros

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANAT ACHIRON ET AL: "Molecular Profiling of Glatiramer Acetate Early Treatment Effects in Multiple Sclerosis", DISEASE MARKERS, 1 January 2009 (2009-01-01), Netherlands, pages 63 - 73, XP055287188, Retrieved from the Internet <URL:http://downloads.hindawi.com/journals/dm/2009/267581.pdf> DOI: 10.1155/2009/267581 *
FADI TOWFIC ET AL: "Comparing the Biological Impact of Glatiramer Acetate with the Biological Impact of a Generic", PLOS ONE, vol. 9, no. 1, 8 January 2014 (2014-01-08), pages e83757, XP055264014, DOI: 10.1371/journal.pone.0083757 *
MADHAN THAMILARASAN ET AL: "Glatiramer acetate treatment effects on gene expression in monocytes of multiple sclerosis patients", JOURNAL OF NEUROINFLAMMATION, vol. 10, no. 1, 17 October 2013 (2013-10-17), pages 126, XP055170927, ISSN: 1742-2094, DOI: 10.1186/1742-2094-10-126 *
SARAH KOLITZ ET AL: "Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids", SCIENTIFIC REPORTS, vol. 5, no. 1, 22 May 2015 (2015-05-22), XP055423415, DOI: 10.1038/srep10191 *
SHLOMO BAKSHI ET AL: "Gene expression analysis reveals functional pathways of glatiramer acetate activation", EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 17, no. 4, 8 March 2013 (2013-03-08), UK, pages 351 - 362, XP055286871, ISSN: 1472-8222, DOI: 10.1517/14728222.2013.778829 *

Also Published As

Publication number Publication date
EP3164710A2 (fr) 2017-05-10
WO2016004250A3 (fr) 2016-03-17
UY36197A (es) 2016-01-29
TW201610169A (zh) 2016-03-16
CA2952849A1 (fr) 2016-01-07
IL249686A0 (en) 2017-02-28
WO2016004250A2 (fr) 2016-01-07

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