EP3143162A4 - Mirna expression signature in the classification of thyroid tumors - Google Patents
Mirna expression signature in the classification of thyroid tumors Download PDFInfo
- Publication number
- EP3143162A4 EP3143162A4 EP15792258.4A EP15792258A EP3143162A4 EP 3143162 A4 EP3143162 A4 EP 3143162A4 EP 15792258 A EP15792258 A EP 15792258A EP 3143162 A4 EP3143162 A4 EP 3143162A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- classification
- mirna expression
- expression signature
- thyroid tumors
- thyroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000024770 Thyroid neoplasm Diseases 0.000 title 1
- 108091070501 miRNA Proteins 0.000 title 1
- 208000013076 thyroid tumor Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461992531P | 2014-05-13 | 2014-05-13 | |
US201461992756P | 2014-05-13 | 2014-05-13 | |
US201462069353P | 2014-10-28 | 2014-10-28 | |
US201562139066P | 2015-03-27 | 2015-03-27 | |
PCT/US2015/030564 WO2015175660A1 (en) | 2014-05-13 | 2015-05-13 | Mirna expression signature in the classification of thyroid tumors |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3143162A1 EP3143162A1 (en) | 2017-03-22 |
EP3143162A4 true EP3143162A4 (en) | 2017-04-26 |
Family
ID=54480610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15792258.4A Pending EP3143162A4 (en) | 2014-05-13 | 2015-05-13 | Mirna expression signature in the classification of thyroid tumors |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP3143162A4 (en) |
JP (1) | JP6216470B2 (en) |
CN (1) | CN106460053A (en) |
BR (1) | BR112016026575A2 (en) |
CA (1) | CA2945531C (en) |
IL (1) | IL248639A0 (en) |
WO (1) | WO2015175660A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106434872A (en) * | 2016-08-11 | 2017-02-22 | 河南大学 | MiRNA molecule marker hsa-miR-152-3p for diagnosing type 2 diabetes, and application thereof |
CN107385093A (en) * | 2017-09-07 | 2017-11-24 | 青岛大学 | Primer composition and its application and application its product and product application method |
CN107723365B (en) * | 2017-09-11 | 2019-10-01 | 朱伟 | One kind blood plasma miRNA marker relevant to lung squamous cancer auxiliary diagnosis and its application |
CN108038352B (en) * | 2017-12-15 | 2021-09-14 | 西安电子科技大学 | Method for mining whole genome key genes by combining differential analysis and association rules |
CA3088939A1 (en) * | 2018-01-05 | 2019-07-11 | Visiongate, Inc. | Morphometric genotyping of cells using optical tomography for detecting tumor mutational burden |
BR102018003587A2 (en) * | 2018-02-23 | 2020-07-07 | Onkos Diagnósticos Moleculares Ltda Me | method and kit for detecting thyroid tumor type |
CN108721318B (en) * | 2018-05-16 | 2021-06-25 | 广东药科大学 | Application of miR-125b and chemotherapeutic agent in preparation of medicine for treating thyroid cancer |
JP7378739B2 (en) * | 2018-08-10 | 2023-11-14 | 東レ株式会社 | Kits, devices and methods for the detection of prostate cancer |
CN109700824A (en) * | 2019-01-08 | 2019-05-03 | 上海长海医院 | Application of the miR-31 and the like in the drug of preparation prevention or treatment blood vessel endothelium injury |
CN110499367B (en) * | 2019-08-09 | 2022-11-22 | 深圳市第二人民医院 | Biomarkers and uses thereof |
CN113025714B (en) * | 2021-03-23 | 2022-05-24 | 华中科技大学同济医学院附属同济医院 | miRNA biomarker for papillary thyroid carcinoma lateral cervical lymph node metastasis diagnosis and detection kit |
CN116769922B (en) * | 2023-08-24 | 2023-11-24 | 四川大学华西医院 | Application of reagent for detecting circulating sEV RNA, kit and diagnostic system |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013063544A1 (en) * | 2011-10-27 | 2013-05-02 | Asuragen, Inc. | Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011154008A1 (en) * | 2010-06-11 | 2011-12-15 | Rigshospitalet | Microrna classification of thyroid follicular neoplasia |
JP2014511677A (en) * | 2011-03-22 | 2014-05-19 | コーネル・ユニバーシティー | Distinguishing benign and malignant thyroid lesions that are difficult to distinguish |
-
2015
- 2015-05-13 JP JP2016567582A patent/JP6216470B2/en not_active Expired - Fee Related
- 2015-05-13 WO PCT/US2015/030564 patent/WO2015175660A1/en active Application Filing
- 2015-05-13 CN CN201580024961.9A patent/CN106460053A/en active Pending
- 2015-05-13 CA CA2945531A patent/CA2945531C/en not_active Expired - Fee Related
- 2015-05-13 EP EP15792258.4A patent/EP3143162A4/en active Pending
- 2015-05-13 BR BR112016026575A patent/BR112016026575A2/en not_active Application Discontinuation
-
2016
- 2016-10-31 IL IL248639A patent/IL248639A0/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013063544A1 (en) * | 2011-10-27 | 2013-05-02 | Asuragen, Inc. | Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors |
Non-Patent Citations (5)
Title |
---|
H. MAZEH: "MicroRNA as a Diagnostic Tool in Fine-Needle Aspiration Biopsy of Thyroid Nodules", THE ONCOLOGIST, vol. 17, no. 8, 15 June 2012 (2012-06-15), US, pages 1032 - 1038, XP055355012, ISSN: 1083-7159, DOI: 10.1634/theoncologist.2012-0013 * |
NIKIFOROVA MARINA N ET AL: "MicroRNA expression profiling of thyroid tumors: Biological significance and diagnostic utility", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, THE ENDOCRINE SOCIETY, US, vol. 93, no. 5, 1 May 2008 (2008-05-01), pages 1600 - 1608, XP002636292, ISSN: 0021-972X, [retrieved on 20080212], DOI: 10.1210/JC.2007-2696 * |
PIERLORENZO PALLANTE ET AL: "Deregulation of microRNA expression in thyroid neoplasias", NATURE REVIEWS. ENDOCRINOLOGY, vol. 10, no. 2, 19 November 2013 (2013-11-19), US, pages 88 - 101, XP055355049, ISSN: 1759-5029, DOI: 10.1038/nrendo.2013.223 * |
See also references of WO2015175660A1 * |
ZI-MING YUAN ET AL: "Deregulation of microRNA expression in thyroid tumors", ZHEJIANG UNIVERSITY. JOURNAL. SCIENCE B: INTERNATIONAL BIOMEDICINE & BIOTECHNOLOGY JOURNAL, vol. 15, no. 3, 1 March 2014 (2014-03-01), CN, pages 212 - 224, XP055355031, ISSN: 1673-1581, DOI: 10.1631/jzus.B1300192 * |
Also Published As
Publication number | Publication date |
---|---|
JP2017521051A (en) | 2017-08-03 |
IL248639A0 (en) | 2017-01-31 |
WO2015175660A1 (en) | 2015-11-19 |
CA2945531A1 (en) | 2015-11-19 |
BR112016026575A2 (en) | 2017-12-12 |
CA2945531C (en) | 2018-01-30 |
EP3143162A1 (en) | 2017-03-22 |
CN106460053A (en) | 2017-02-22 |
JP6216470B2 (en) | 2017-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL248639A0 (en) | Mirna expression signature in the classification of thyroid tumors | |
EP3229838A4 (en) | Anti-c10orf54 antibodies and uses thereof | |
EP3283983A4 (en) | Structural document classification | |
EP3180730A4 (en) | Environment-aware security tokens | |
EP3179879A4 (en) | Card wallet | |
EP3099677A4 (en) | Diaminopyrimidine benzenesulfone derivatives and uses thereof | |
EP3155086A4 (en) | Size alternating injection into drops to facilitate sorting | |
EP3100496A4 (en) | Measurement in mbms | |
EP3171428A4 (en) | Usb terminal-equipped battery | |
GB201401528D0 (en) | Social matching and interaction | |
EP3123386A4 (en) | Granting permission in association with an application | |
EP3117449A4 (en) | Smart chamber and smart chamber components | |
EP3202909A4 (en) | Cancer specific-splicing ribozyme and use thereof | |
EP3223867A4 (en) | Radioembolic particles | |
HUE049806T2 (en) | Modified host cells and uses thereof | |
EP3146121A4 (en) | Modified pocket former | |
EP3270741A4 (en) | Smart pillow | |
EP3213769A4 (en) | Transdermal-absorption-promoter and transdermal-absorption-promoting supplement | |
EP3180004A4 (en) | Cancer therapeutics | |
EP3164825A4 (en) | Deconstructing overlapped peaks in experimental data | |
EP3143579A4 (en) | Suggested keywords | |
GB201411044D0 (en) | Copolyestermides and films made therefrom | |
EP3149039B8 (en) | Anti-neurotensin antibodies and uses thereof | |
EP3233919A4 (en) | Dicam-specific antibodies and uses thereof | |
EP3108012A4 (en) | Mir-320e and colorectal cancer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20161208 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20170323 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101AFI20170317BHEP |
|
17Q | First examination report despatched |
Effective date: 20170406 |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
19U | Interruption of proceedings before grant |
Effective date: 20181022 |
|
19W | Proceedings resumed before grant after interruption of proceedings |
Effective date: 20220801 |
|
PUAJ | Public notification under rule 129 epc |
Free format text: ORIGINAL CODE: 0009425 |
|
32PN | Public notification |
Free format text: COMMUNICATION PURSUANT TO RULE 142 EPC (RESUMPTION OF PROCEEDINGS UNDER RULE 142(2) EPC DATED 22.04.2022) |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20221001 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
D18D | Application deemed to be withdrawn (deleted) | ||
PUAJ | Public notification under rule 129 epc |
Free format text: ORIGINAL CODE: 0009425 |
|
32PN | Public notification |
Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 2021A DATED 10.03.2023) |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
R18D | Application deemed to be withdrawn (corrected) |
Effective date: 20221001 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
D18D | Application deemed to be withdrawn (deleted) | ||
R18D | Application deemed to be withdrawn (corrected) |
Effective date: 20221001 |