EP3132270A4 - Verfahren zur diagnose von tuberkulöser meningitis - Google Patents

Verfahren zur diagnose von tuberkulöser meningitis Download PDF

Info

Publication number
EP3132270A4
EP3132270A4 EP15779954.5A EP15779954A EP3132270A4 EP 3132270 A4 EP3132270 A4 EP 3132270A4 EP 15779954 A EP15779954 A EP 15779954A EP 3132270 A4 EP3132270 A4 EP 3132270A4
Authority
EP
European Patent Office
Prior art keywords
tuberculous meningitis
diagnosing tuberculous
diagnosing
meningitis
tuberculous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15779954.5A
Other languages
English (en)
French (fr)
Other versions
EP3132270A1 (de
Inventor
Novel Njweipi Chegou
Gerhard Walzl
Anne Marceline VAN FURTH
Douwe Hendrik VISSER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stellenbosch University
Original Assignee
Stellenbosch University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stellenbosch University filed Critical Stellenbosch University
Publication of EP3132270A1 publication Critical patent/EP3132270A1/de
Publication of EP3132270A4 publication Critical patent/EP3132270A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4721—Cationic antimicrobial peptides, e.g. defensins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5437—IL-13

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP15779954.5A 2014-04-15 2015-04-15 Verfahren zur diagnose von tuberkulöser meningitis Withdrawn EP3132270A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA201402743 2014-04-15
PCT/IB2015/052751 WO2015159239A1 (en) 2014-04-15 2015-04-15 A method for diagnosing tuberculous meningitis

Publications (2)

Publication Number Publication Date
EP3132270A1 EP3132270A1 (de) 2017-02-22
EP3132270A4 true EP3132270A4 (de) 2017-09-13

Family

ID=54323552

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15779954.5A Withdrawn EP3132270A4 (de) 2014-04-15 2015-04-15 Verfahren zur diagnose von tuberkulöser meningitis

Country Status (5)

Country Link
EP (1) EP3132270A4 (de)
CN (1) CN106461674A (de)
AP (1) AP2016009538A0 (de)
RU (1) RU2016144359A (de)
WO (1) WO2015159239A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017178826A1 (en) * 2016-04-14 2017-10-19 The University Of Liverpool Diagnosing acute bacterial meningitis
CN107421875A (zh) * 2017-04-29 2017-12-01 济南市儿童医院 Mfsd2a在制备诊断化脓性脑膜炎制品中的应用
US20210199668A1 (en) * 2018-05-23 2021-07-01 Stellenbosch University Biomarkers for diagnosing tuberculous meningitis
CN112899340B (zh) * 2021-03-15 2022-09-27 首都医科大学附属北京胸科医院 一种辅助诊断结核性脑膜炎的试剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013175459A2 (en) * 2012-05-25 2013-11-28 Stellenbosch University Method for diagnosing tuberculosis disease
US20140080732A1 (en) * 2008-06-25 2014-03-20 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE479097T1 (de) * 2001-05-18 2010-09-15 Virogates Aps Verfahren zur diagnose oder prognostizierung der wesentlichen bakteriellen erreger von atemwegserkrankungen in einem patienten
NZ580805A (en) * 2004-07-23 2011-02-25 Aspenbio Pharma Inc Methods and devices for diagnosis of appendicitis
JP2011526152A (ja) * 2008-06-25 2011-10-06 ベイラー リサーチ インスティテュート マイコバクテリウム・ツベルクローシス感染症の血液転写サイン

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140080732A1 (en) * 2008-06-25 2014-03-20 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
WO2013175459A2 (en) * 2012-05-25 2013-11-28 Stellenbosch University Method for diagnosing tuberculosis disease

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MARTINEAU A.R. ET AL.: "Neutrophil-mediated innate immune resistance to mycobacteria", J. CLIN. INVEST., vol. 117, no. 7, July 2007 (2007-07-01), pages 1988 - 1994, XP055396236 *
See also references of WO2015159239A1 *
VISSER D.H. ET AL.: "Host immune response to tuberculous meningitis", CLIN. INFECT. DIS., vol. 60, no. 2, 9 October 2014 (2014-10-09), pages 177 - 187, XP055395968 *

Also Published As

Publication number Publication date
CN106461674A (zh) 2017-02-22
WO2015159239A1 (en) 2015-10-22
WO2015159239A4 (en) 2015-12-17
AP2016009538A0 (en) 2016-11-30
EP3132270A1 (de) 2017-02-22
RU2016144359A3 (de) 2018-05-15
RU2016144359A (ru) 2018-05-15

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Effective date: 20170814

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