EP3117165A4 - Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost - Google Patents

Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost Download PDF

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Publication number
EP3117165A4
EP3117165A4 EP14885084.5A EP14885084A EP3117165A4 EP 3117165 A4 EP3117165 A4 EP 3117165A4 EP 14885084 A EP14885084 A EP 14885084A EP 3117165 A4 EP3117165 A4 EP 3117165A4
Authority
EP
European Patent Office
Prior art keywords
pressure differential
freeze drying
ice crystals
during freezing
drying cycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14885084.5A
Other languages
German (de)
French (fr)
Other versions
EP3117165A1 (en
EP3117165B1 (en
Inventor
Weijia LING
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millrock Technology Inc
Original Assignee
Millrock Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/205,802 external-priority patent/US9435586B2/en
Application filed by Millrock Technology Inc filed Critical Millrock Technology Inc
Priority to EP19214972.2A priority Critical patent/EP3640573B1/en
Publication of EP3117165A1 publication Critical patent/EP3117165A1/en
Publication of EP3117165A4 publication Critical patent/EP3117165A4/en
Application granted granted Critical
Publication of EP3117165B1 publication Critical patent/EP3117165B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
EP14885084.5A 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost Active EP3117165B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP19214972.2A EP3640573B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/205,802 US9435586B2 (en) 2012-08-13 2014-03-12 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
PCT/US2014/056192 WO2015138005A1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP19214972.2A Division EP3640573B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
EP19214972.2A Division-Into EP3640573B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Publications (3)

Publication Number Publication Date
EP3117165A1 EP3117165A1 (en) 2017-01-18
EP3117165A4 true EP3117165A4 (en) 2017-11-22
EP3117165B1 EP3117165B1 (en) 2020-03-25

Family

ID=54072247

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19214972.2A Active EP3640573B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
EP14885084.5A Active EP3117165B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP19214972.2A Active EP3640573B1 (en) 2014-03-12 2014-09-18 Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Country Status (5)

Country Link
EP (2) EP3640573B1 (en)
JP (1) JP6389270B2 (en)
CN (2) CN110108097A (en)
ES (1) ES2799600T3 (en)
WO (1) WO2015138005A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110108097A (en) * 2014-03-12 2019-08-09 米尔洛克科技公司 The controlled nucleation of the pressure difference ice crystal distribution come autocondensation frost is utilized in the refrigerating process of freeze-drying circulation
ES2774058T3 (en) 2017-04-21 2020-07-16 Gea Lyophil Gmbh A lyophilizer and a method of inducing nucleation in products
WO2022175999A1 (en) * 2021-02-16 2022-08-25 株式会社アルバック Freeze-drying apparatus and freeze-drying method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140041250A1 (en) * 2012-08-13 2014-02-13 Weijia Ling Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350568A (en) * 1981-04-15 1982-09-21 Dalupan Romulo V High efficiency water distillation apparatus
EP1563237A2 (en) * 2002-11-21 2005-08-17 Transform Pharmaceuticals, Inc. Freeze-drying microscope stage apparatus and process of using the same
CN101379356B (en) * 2006-02-10 2013-07-17 普莱克斯技术有限公司 Method of inducing nucleation of a material
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
US20110179667A1 (en) * 2009-09-17 2011-07-28 Lee Ron C Freeze drying system
US8549768B2 (en) * 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
US8839528B2 (en) * 2011-04-29 2014-09-23 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice fog distribution
CN110108097A (en) * 2014-03-12 2019-08-09 米尔洛克科技公司 The controlled nucleation of the pressure difference ice crystal distribution come autocondensation frost is utilized in the refrigerating process of freeze-drying circulation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140041250A1 (en) * 2012-08-13 2014-02-13 Weijia Ling Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost

Also Published As

Publication number Publication date
ES2799600T3 (en) 2020-12-18
EP3640573A1 (en) 2020-04-22
EP3117165A1 (en) 2017-01-18
JP6389270B2 (en) 2018-09-12
EP3117165B1 (en) 2020-03-25
EP3640573B1 (en) 2024-05-22
CN106255860A (en) 2016-12-21
CN106255860B (en) 2019-06-18
WO2015138005A1 (en) 2015-09-17
CN110108097A (en) 2019-08-09
JP2017508126A (en) 2017-03-23

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