EP3079680A4 - Compositions and methods for treating, preventing and diagnosing cancer and other proliferative disorders - Google Patents

Compositions and methods for treating, preventing and diagnosing cancer and other proliferative disorders Download PDF

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Publication number
EP3079680A4
EP3079680A4 EP14870415.8A EP14870415A EP3079680A4 EP 3079680 A4 EP3079680 A4 EP 3079680A4 EP 14870415 A EP14870415 A EP 14870415A EP 3079680 A4 EP3079680 A4 EP 3079680A4
Authority
EP
European Patent Office
Prior art keywords
compositions
treating
preventing
methods
proliferative disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14870415.8A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3079680A2 (en
Inventor
William A. Garland
Jaideep Chaudhary
Glen STOLLER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiogenex Inc
Original Assignee
Angiogenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiogenex Inc filed Critical Angiogenex Inc
Publication of EP3079680A2 publication Critical patent/EP3079680A2/en
Publication of EP3079680A4 publication Critical patent/EP3079680A4/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP14870415.8A 2013-12-13 2014-12-14 Compositions and methods for treating, preventing and diagnosing cancer and other proliferative disorders Withdrawn EP3079680A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361916116P 2013-12-13 2013-12-13
US201461965776P 2014-02-06 2014-02-06
PCT/US2014/070221 WO2015089495A2 (en) 2013-12-13 2014-12-14 Compositions and methods for treating, preventing and diagnosing cancer and other proliferative disorders

Publications (2)

Publication Number Publication Date
EP3079680A2 EP3079680A2 (en) 2016-10-19
EP3079680A4 true EP3079680A4 (en) 2017-11-22

Family

ID=53371974

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14870415.8A Withdrawn EP3079680A4 (en) 2013-12-13 2014-12-14 Compositions and methods for treating, preventing and diagnosing cancer and other proliferative disorders

Country Status (6)

Country Link
EP (1) EP3079680A4 (enExample)
JP (2) JP2017506257A (enExample)
CN (1) CN107847470A (enExample)
AU (1) AU2014361814A1 (enExample)
MX (1) MX2016007748A (enExample)
WO (1) WO2015089495A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11000548B2 (en) 2015-02-18 2021-05-11 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11304976B2 (en) 2015-02-18 2022-04-19 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
CN113106053A (zh) 2015-04-21 2021-07-13 恩立夫克治疗有限责任公司 治疗性汇集的血液凋亡细胞制剂与其用途
EP3416661A4 (en) 2016-02-18 2020-03-04 Enlivex Therapeutics Ltd. COMBINATION OF IMMUNOTHERAPY AND CYTOKINE CONTROL THERAPY FOR THE TREATMENT OF CANCER
LU100900B1 (de) * 2018-08-10 2020-02-17 Thomas Melchior Homann Verbindungen zur modulation von a-ketoglutarsäure (2kg)-abhängigen oxygenasen
EP3760614B8 (en) * 2019-07-02 2022-04-27 Universität Heidelberg Chemical inhibitors of id proteins for the treatment of cancer and other diseases
JP2022550589A (ja) * 2019-10-01 2022-12-02 メモリアル スローン ケタリング キャンサー センター Ｉｄタンパク質の小分子阻害剤
CN113627763B (zh) * 2021-07-30 2023-12-01 厦门大学 一种风险量化评估模型建立方法
CN114480490A (zh) * 2021-12-31 2022-05-13 四川省医学科学院·四川省人民医院 一种构建视网膜新生血管性疾病动物模型的方法
CN115487358B (zh) * 2022-08-05 2023-05-30 核工业四一六医院 一种用于软骨组织修复的凝胶复合支架及制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090226422A1 (en) * 2007-10-16 2009-09-10 Jaideep Chaudhary Chemical Inhibitors of Inhibitors of Differentiation
WO2013025939A2 (en) * 2011-08-16 2013-02-21 Indiana University Research And Technology Corporation Compounds and methods for treating cancer by inhibiting the urokinase receptor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012000036A1 (en) * 2010-06-30 2012-01-05 Garvan Institute Of Medical Research Treatment of abnormalities of glucose metabolism with an antagonist of inhibitor of differentiation 1

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090226422A1 (en) * 2007-10-16 2009-09-10 Jaideep Chaudhary Chemical Inhibitors of Inhibitors of Differentiation
WO2013025939A2 (en) * 2011-08-16 2013-02-21 Indiana University Research And Technology Corporation Compounds and methods for treating cancer by inhibiting the urokinase receptor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JAIDEEP CHAUDHARY ET AL: "A novel small molecule inhibitor of Id proteins (AGX-51) blocks cell survival in vitro and diminishes angiogenesis and tumor growth in vivo", THE FASEB JOURNAL, SUPPLEMENT, vol. 23, no. 1, 1 April 2009 (2009-04-01), pages 761.4, XP055388618 *
TIMMY MANI ET AL: "Probing Binding and Cellular Activity of Pyrrolidinone and Piperidinone Small Molecules Targeting the Urokinase Receptor", CHEMMEDCHEM, vol. 8, no. 12, 2 December 2013 (2013-12-02), DE, pages 1963 - 1977, XP055386919, ISSN: 1860-7179, DOI: 10.1002/cmdc.201300340 *

Also Published As

Publication number Publication date
WO2015089495A2 (en) 2015-06-18
WO2015089495A3 (en) 2015-11-12
EP3079680A2 (en) 2016-10-19
JP2019203028A (ja) 2019-11-28
AU2014361814A1 (en) 2016-07-28
MX2016007748A (es) 2017-07-28
JP2017506257A (ja) 2017-03-02
CN107847470A (zh) 2018-03-27

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 35/04 20060101ALI20170714BHEP

Ipc: A61K 31/36 20060101ALI20170714BHEP

Ipc: A61K 45/06 20060101ALI20170714BHEP

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