EP2958559A4 - Verwendung einer omega-3-emulsion auf lipidbasis zum schutz von organen vor ischämischer läsion - Google Patents

Verwendung einer omega-3-emulsion auf lipidbasis zum schutz von organen vor ischämischer läsion

Info

Publication number
EP2958559A4
EP2958559A4 EP14754815.0A EP14754815A EP2958559A4 EP 2958559 A4 EP2958559 A4 EP 2958559A4 EP 14754815 A EP14754815 A EP 14754815A EP 2958559 A4 EP2958559 A4 EP 2958559A4
Authority
EP
European Patent Office
Prior art keywords
omega
lipid
based emulsion
ischemic injury
human organs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14754815.0A
Other languages
English (en)
French (fr)
Other versions
EP2958559A1 (de
Inventor
Richard J Deckelbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of EP2958559A1 publication Critical patent/EP2958559A1/de
Publication of EP2958559A4 publication Critical patent/EP2958559A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP14754815.0A 2013-02-20 2014-02-20 Verwendung einer omega-3-emulsion auf lipidbasis zum schutz von organen vor ischämischer läsion Withdrawn EP2958559A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361767248P 2013-02-20 2013-02-20
PCT/US2014/017523 WO2014130746A1 (en) 2013-02-20 2014-02-20 Use of an omega-3 lipid-based emulsion for protecting human organs from ischemic injury

Publications (2)

Publication Number Publication Date
EP2958559A1 EP2958559A1 (de) 2015-12-30
EP2958559A4 true EP2958559A4 (de) 2016-07-20

Family

ID=51391828

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14754815.0A Withdrawn EP2958559A4 (de) 2013-02-20 2014-02-20 Verwendung einer omega-3-emulsion auf lipidbasis zum schutz von organen vor ischämischer läsion

Country Status (3)

Country Link
EP (1) EP2958559A4 (de)
CN (1) CN105120858A (de)
WO (1) WO2014130746A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115697088A (zh) * 2020-05-02 2023-02-03 鲍斯生命科学Pvt有限公司 富含ω脂肪酸的油分散制剂

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1279400A1 (de) * 2001-07-25 2003-01-29 Target Hit sa Änderung der Fettsäurezusammensetzung Organ- und Gewebe-Zellmembranen
WO2007059431A1 (en) * 2005-11-14 2007-05-24 The Trustees Of Columbia University In The City Of New York Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs
WO2008036353A2 (en) * 2006-09-19 2008-03-27 The Trustees Of Columbia University In The City Of New York Omega-3 diglyceride emulsions
WO2009014452A1 (en) * 2007-07-25 2009-01-29 Epax As Omega-3 fatty acid fortified composition
WO2010104575A2 (en) * 2009-03-11 2010-09-16 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US20110206741A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation DHA Triglyceride Emulsions
WO2011133841A2 (en) * 2010-04-23 2011-10-27 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Intravenous omega-3 fatty acid compositions & method of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444432B1 (en) * 1997-06-13 2002-09-03 Alan M. Kleinfeld Method of detection of cardiac ischemia using fatty acid binding protein

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1279400A1 (de) * 2001-07-25 2003-01-29 Target Hit sa Änderung der Fettsäurezusammensetzung Organ- und Gewebe-Zellmembranen
WO2007059431A1 (en) * 2005-11-14 2007-05-24 The Trustees Of Columbia University In The City Of New York Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs
WO2008036353A2 (en) * 2006-09-19 2008-03-27 The Trustees Of Columbia University In The City Of New York Omega-3 diglyceride emulsions
WO2009014452A1 (en) * 2007-07-25 2009-01-29 Epax As Omega-3 fatty acid fortified composition
WO2010104575A2 (en) * 2009-03-11 2010-09-16 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US20110206741A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation DHA Triglyceride Emulsions
WO2011133841A2 (en) * 2010-04-23 2011-10-27 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Intravenous omega-3 fatty acid compositions & method of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ATSUHIRO ARISUE ET AL: "Effect of an omega-3 lipid emulsion in reducing oxidative stress in a rat model of intestinal ischemia-reperfusion injury", PEDIATRIC SURGERY INTERNATIONAL, SPRINGER, BERLIN, DE, vol. 28, no. 9, 21 August 2012 (2012-08-21), pages 913 - 918, XP035108298, ISSN: 1437-9813, DOI: 10.1007/S00383-012-3144-0 *
See also references of WO2014130746A1 *

Also Published As

Publication number Publication date
WO2014130746A1 (en) 2014-08-28
CN105120858A (zh) 2015-12-02
EP2958559A1 (de) 2015-12-30

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