EP2950794A4 - Composition for binding aldehydes in the mouth - Google Patents

Composition for binding aldehydes in the mouth

Info

Publication number
EP2950794A4
EP2950794A4 EP14746925.8A EP14746925A EP2950794A4 EP 2950794 A4 EP2950794 A4 EP 2950794A4 EP 14746925 A EP14746925 A EP 14746925A EP 2950794 A4 EP2950794 A4 EP 2950794A4
Authority
EP
European Patent Office
Prior art keywords
mouth
composition
binding aldehydes
aldehydes
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14746925.8A
Other languages
German (de)
French (fr)
Other versions
EP2950794A1 (en
Inventor
Osmo Suovaniemi
Mikko Salaspuro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biohit Oy
Original Assignee
Biohit Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oy filed Critical Biohit Oy
Publication of EP2950794A1 publication Critical patent/EP2950794A1/en
Publication of EP2950794A4 publication Critical patent/EP2950794A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP14746925.8A 2013-02-01 2014-01-31 Composition for binding aldehydes in the mouth Withdrawn EP2950794A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20135097A FI20135097L (en) 2013-02-01 2013-02-01 Composition for binding aldehydes in the mouth
PCT/FI2014/050076 WO2014118438A1 (en) 2013-02-01 2014-01-31 Composition for binding aldehydes in the mouth

Publications (2)

Publication Number Publication Date
EP2950794A1 EP2950794A1 (en) 2015-12-09
EP2950794A4 true EP2950794A4 (en) 2016-11-09

Family

ID=51261516

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14746925.8A Withdrawn EP2950794A4 (en) 2013-02-01 2014-01-31 Composition for binding aldehydes in the mouth

Country Status (6)

Country Link
EP (1) EP2950794A4 (en)
CN (2) CN108969500A (en)
EA (1) EA201591203A1 (en)
FI (1) FI20135097L (en)
MX (1) MX2015009972A (en)
WO (1) WO2014118438A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI127823B (en) * 2015-03-06 2019-03-15 Biohit Oyj Composition for preventing hangover symptoms

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036098A1 (en) * 2000-10-30 2002-05-10 Licentia Ltd Method and preparation for binding acetaldehyde in saliva, stomach and large intestine
WO2006103316A1 (en) * 2005-04-01 2006-10-05 Biohit Oyj Food composition for binding acetaldehyde in mouth and in digestive track, and method for the preparation of the composition
WO2012143608A2 (en) * 2011-04-18 2012-10-26 Biohit Oyj Medical products for use in conditions related to microbial infections in the upper aerodigestive tract

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006037848A1 (en) * 2004-10-08 2006-04-13 Biohit Oyj Method and preparation for binding aldehydes in saliva
FI20070705L (en) * 2007-09-14 2009-06-02 Biohit Oyj Binding of acetaldehyde in the mouth and in the stomach
US20090197956A1 (en) * 2008-02-04 2009-08-06 Arbor Pharmaceuticals, Inc. Treatment of acute otitis media with xylitol and n-acetylcysteine
FI20115680L (en) * 2011-06-29 2012-12-30 Biohit Oyj Liquid pharmaceutical compositions or combination products

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036098A1 (en) * 2000-10-30 2002-05-10 Licentia Ltd Method and preparation for binding acetaldehyde in saliva, stomach and large intestine
WO2006103316A1 (en) * 2005-04-01 2006-10-05 Biohit Oyj Food composition for binding acetaldehyde in mouth and in digestive track, and method for the preparation of the composition
WO2012143608A2 (en) * 2011-04-18 2012-10-26 Biohit Oyj Medical products for use in conditions related to microbial infections in the upper aerodigestive tract

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALMA KARTAL ET AL: "Compatibility of chewing gum excipients with the amino acid l-cysteine and stability of the active substance in directly compressed chewing gum formulation", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 60, no. 9, 1 September 2008 (2008-09-01), LONDON; GB, pages 1131 - 1138, XP055284963, ISSN: 0022-3573, DOI: 10.1211/jpp.60.9.0003 *
JOHANNA UITTAMO ET AL: "Xylitol inhibits carcinogenic acetaldehyde production by Candida species", INTERNATIONAL JOURNAL OF CANCER, vol. 129, no. 8, 15 October 2011 (2011-10-15), US, pages 2038 - 2041, XP055284956, ISSN: 0020-7136, DOI: 10.1002/ijc.25844 *
SALASPURO V J ET AL: "Eliminating Carcinogenic Acetaldehyde by Cysteine From Saliva During Smoking", CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION, PHILADELPHIA, PA, US, vol. 15, no. 1, 1 January 2006 (2006-01-01), pages 146 - 149, XP002449219, ISSN: 1055-9965, DOI: 10.1158/1055-9965.EPI-05-0248 *
See also references of WO2014118438A1 *

Also Published As

Publication number Publication date
WO2014118438A1 (en) 2014-08-07
FI20135097L (en) 2014-08-02
CN108969500A (en) 2018-12-11
MX2015009972A (en) 2016-03-11
EA201591203A1 (en) 2016-01-29
CN105307649A (en) 2016-02-03
EP2950794A1 (en) 2015-12-09

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Ipc: A61K 31/198 20060101AFI20161004BHEP

Ipc: A61K 9/20 20060101ALI20161004BHEP

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