EP2938626A4 - Self-assembled ultrashort peptides hydrogels for wound healing, skin care and cosmetics applications - Google Patents

Self-assembled ultrashort peptides hydrogels for wound healing, skin care and cosmetics applications

Info

Publication number
EP2938626A4
EP2938626A4 EP13869801.4A EP13869801A EP2938626A4 EP 2938626 A4 EP2938626 A4 EP 2938626A4 EP 13869801 A EP13869801 A EP 13869801A EP 2938626 A4 EP2938626 A4 EP 2938626A4
Authority
EP
European Patent Office
Prior art keywords
assembled
self
wound healing
skin care
cosmetics applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13869801.4A
Other languages
German (de)
French (fr)
Other versions
EP2938626A1 (en
Inventor
Charlotte Hauser
Yihua Loo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Original Assignee
Agency for Science Technology and Research Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore filed Critical Agency for Science Technology and Research Singapore
Publication of EP2938626A1 publication Critical patent/EP2938626A1/en
Publication of EP2938626A4 publication Critical patent/EP2938626A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP13869801.4A 2012-12-31 2013-12-31 Self-assembled ultrashort peptides hydrogels for wound healing, skin care and cosmetics applications Withdrawn EP2938626A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG2012096699A SG2012096699A (en) 2012-12-31 2012-12-31 Amphiphilic linear peptide/peptoid and hydrogel comprising the same
PCT/SG2013/000564 WO2014104981A1 (en) 2012-12-31 2013-12-31 Self-assembled ultrashort peptides hydrogels for wound healing, skin care and cosmetics applications

Publications (2)

Publication Number Publication Date
EP2938626A1 EP2938626A1 (en) 2015-11-04
EP2938626A4 true EP2938626A4 (en) 2016-08-17

Family

ID=54063251

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13869801.4A Withdrawn EP2938626A4 (en) 2012-12-31 2013-12-31 Self-assembled ultrashort peptides hydrogels for wound healing, skin care and cosmetics applications

Country Status (4)

Country Link
EP (1) EP2938626A4 (en)
CN (1) CN105189532B (en)
SG (2) SG2012096699A (en)
WO (1) WO2014104981A1 (en)

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CA2931954A1 (en) * 2013-11-30 2015-06-04 Agency For Science, Technology And Research Novel ultrashort hydrophobic peptides that self-assemble into nanofibrous hydrogels and their uses
WO2015080671A1 (en) * 2013-11-30 2015-06-04 Agency For Science, Technology And Research Self-assembling peptides, peptidomimetics and peptidic conjugates as building blocks for biofabrication and printing
SG11201610950RA (en) * 2014-07-08 2017-01-27 Agency Science Tech & Res Ultrashort peptides as exogenous second harmonic probes for bioimaging applications
DE102015000363A1 (en) * 2015-01-20 2016-07-21 Emc Microcollections Gmbh New modular functionalizable peptide hydrogels
CN107406487A (en) * 2015-03-06 2017-11-28 新加坡科技研究局 The ultrashort aliphatic depsipeptides of self assembly for biomedical applications
WO2016149363A1 (en) * 2015-03-16 2016-09-22 Northwestern University Contrast-agent-labeled peptide amphiphile nanofibers
WO2016159886A1 (en) * 2015-03-31 2016-10-06 Agency For Science, Technology And Research Self-assembling ultrashort aliphatic cyclic peptides for biomedical applications
WO2017066545A1 (en) 2015-10-14 2017-04-20 Northwestern University Nanofiber paste for growth factor delivery and bone regeneration
GB201523102D0 (en) * 2015-12-30 2016-02-10 Augmented Optics Ltd Electrically active hydrophilic bio-polymers
CN106083634B (en) * 2016-06-16 2017-12-05 淮阴师范学院 A kind of peptide amphiphile molecule and its preparation method and application
CN106432430B (en) * 2016-08-17 2019-11-05 广州宏柯源生物科技有限公司 A kind of polypeptide, preparation method and application
CN110325204B (en) * 2016-09-09 2023-11-07 纽约城市大学研究基金会 Self-assembled peptide polymers
KR101829051B1 (en) * 2016-10-31 2018-02-13 주식회사 삼양사 Thick hydrogel sheet with high adhesive power
CA3057150A1 (en) * 2017-04-12 2018-10-18 X-Therma, Inc. Novel peptoid polymers and methods of use
KR102611274B1 (en) 2017-05-11 2023-12-07 킹 압둘라 유니버시티 오브 사이언스 앤드 테크놀로지 Peptides capable of forming gels for use in tissue processing and bioprinting
US11702623B2 (en) 2017-05-11 2023-07-18 King Abdullah University Of Science And Technology Device and method for microfluidics-based 3D bioprinting
US11472841B2 (en) * 2018-01-19 2022-10-18 Menicon Co., Ltd. Immunogenic composition
CN108912348B (en) * 2018-07-28 2021-07-02 邹立人 Short peptide hydrogel containing protein and method for improving storage stability of protein
US20210386907A1 (en) * 2018-10-16 2021-12-16 William Marsh Rice University Neutral multidomain peptide hydrogels and uses thereof
CN109456389B (en) * 2018-12-25 2021-06-01 苏州大学 Antibacterial peptide, antibacterial peptide hydrogel and preparation method thereof
JP7159861B2 (en) * 2018-12-27 2022-10-25 株式会社Sumco Double-headed grinding method
WO2020162835A1 (en) * 2019-02-08 2020-08-13 Agency For Science, Technology And Research A self-assembling short amphiphilic peptide and related methods and uses
JP6873436B2 (en) * 2019-05-17 2021-05-19 学校法人大阪医科薬科大学 Pharmaceutical composition for the treatment of joint diseases and its manufacturing method
CN110169950B (en) * 2019-07-04 2023-01-24 中原工学院 Injectable antibacterial peptide hydrogel and preparation method thereof
CN112724823B (en) * 2019-10-28 2022-08-02 华东理工大学 Application of polypeptide polymer
CN111760075B (en) * 2020-07-08 2021-08-13 西南交通大学 Antibacterial anticoagulation coating, preparation method thereof and medical material
US11673324B2 (en) 2020-08-20 2023-06-13 King Abdullah University Of Science And Technology Nozzle for 3D bioprinting
WO2022049508A1 (en) * 2020-09-02 2022-03-10 King Adbullah University Of Science And Technology Peptide-based dopa containing adhesive gels
CN113577014B (en) * 2020-12-30 2023-03-24 广州图微科创生物科技有限公司 Medical apparatus and instrument, hydrogel and preparation method and application thereof
CN112940077B (en) * 2021-02-03 2023-01-03 中山大学孙逸仙纪念医院 Polypeptide hydrogel loaded with small interfering RNA (ribonucleic acid), and preparation method and application thereof
AU2022244477A1 (en) * 2021-03-21 2023-10-05 Bone Sci. Bio Ltd. Dermatological compositions and use thereof
CN115340592A (en) * 2021-09-09 2022-11-15 禾美生物科技(浙江)有限公司 Active peptide and related application thereof
CN114989249B (en) * 2022-05-27 2023-07-21 成都赛恩贝外科学研究院 Nano short peptide R-LIFE-1 and application thereof in medicines, medical cosmetology and biomedicine
CN115678044B (en) * 2022-11-08 2023-05-19 郑州大学 Proton conductive organic hydrogel based on bovine serum albumin and preparation and application thereof

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WO2011123061A1 (en) * 2010-03-31 2011-10-06 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
WO2011131671A1 (en) * 2010-04-19 2011-10-27 Universita' Degli Studi Di Milano Bicocca Novel self-assembling peptides and their use in the formation of hydrogels

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JP3830386B2 (en) * 2001-12-20 2006-10-04 英夫 吉田 Anodizing method and processing equipment therefor
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CA2660286A1 (en) * 2006-08-09 2008-02-21 Homestead Clinical Corporation Organ-specific proteins and methods of their use
CN107028792A (en) * 2008-05-29 2017-08-11 唐纳德·欧文 Oligomerization biosurfactant in dermato-cosmetic composition
US20100221341A1 (en) * 2009-02-27 2010-09-02 Drexel University Alanine-Based Peptide Hydrogels
EP2773696B1 (en) 2011-11-04 2017-07-26 Agency For Science, Technology And Research Self-assembled composite ultrasmall peptide-polymer hydrogels
SG193042A1 (en) 2012-02-22 2013-09-30 Agency Science Tech & Res Organogels from ultrasmall peptides that can be used for biological and non-biological applications

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2011123061A1 (en) * 2010-03-31 2011-10-06 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
WO2011131671A1 (en) * 2010-04-19 2011-10-27 Universita' Degli Studi Di Milano Bicocca Novel self-assembling peptides and their use in the formation of hydrogels

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARCHANA MISHRA ET AL: "Ultrasmall natural peptides self-assemble to strong temperature-resistant helical fibers in scaffolds suitable for tissue engineering", NANO TODAY, vol. 6, no. 3, 1 June 2011 (2011-06-01), pages 232 - 239, XP055066828, ISSN: 1748-0132, DOI: 10.1016/j.nantod.2011.05.001 *
C A HAUSER: "Natural tri- to hexapeptides self-assemble in water to amyloid P- type fiber aggregates by unexpected a-helical intermediate structures.", PNAS, vol. 108, no. 4, 25 January 2011 (2011-01-25), pages 1361 - 1366, XP055082546, DOI: 10.1073/pnas.1014796108/-/DCSupplemental *
See also references of WO2014104981A1 *
SHUYI HAN ET AL: "Self-Assembly of Short Peptide Amphiphiles: The Cooperative Effect of Hydrophobic Interaction and Hydrogen Bonding", CHEMISTRY - A EUROPEAN JOURNAL., vol. 17, no. 46, 28 September 2011 (2011-09-28), WEINHEIM, DE, pages 13095 - 13102, XP055287071, ISSN: 0947-6539, DOI: 10.1002/chem.201101970 *

Also Published As

Publication number Publication date
CN105189532A (en) 2015-12-23
SG11201505160PA (en) 2015-07-30
WO2014104981A1 (en) 2014-07-03
CN105189532B (en) 2020-11-03
EP2938626A1 (en) 2015-11-04
SG2012096699A (en) 2014-07-30

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