EP2893916B1 - Flüssigkeitsübertragungsvorrichtung mit durchstechelement - Google Patents

Flüssigkeitsübertragungsvorrichtung mit durchstechelement Download PDF

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Publication number
EP2893916B1
EP2893916B1 EP14151085.9A EP14151085A EP2893916B1 EP 2893916 B1 EP2893916 B1 EP 2893916B1 EP 14151085 A EP14151085 A EP 14151085A EP 2893916 B1 EP2893916 B1 EP 2893916B1
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EP
European Patent Office
Prior art keywords
fluid transfer
transfer device
spring member
locking members
adapter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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EP14151085.9A
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English (en)
French (fr)
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EP2893916A1 (de
Inventor
Oguz Bozkurt Cimir
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Tim Plastik ve Kalip Teknolojileri Endustri ve Tic AS
Original Assignee
Tim Plastik ve Kalip Teknolojileri Endustri ve Tic AS
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Priority to EP14151085.9A priority Critical patent/EP2893916B1/de
Priority to PCT/TR2015/000026 priority patent/WO2015108495A1/en
Publication of EP2893916A1 publication Critical patent/EP2893916A1/de
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end

Definitions

  • the present invention relates to a fluid transferring device having improved safety and functional structure which ensures ease of manufacture. More particularly, the invention relates to an adapter device of the type having a piercing member for transferring of medicaments from one vessel to another with an improved functionality and safety while providing a specially designed spring member that simplifies manufacturing of the device.
  • Liquid medicaments, prodrugs, biologic samples or diagnosis agents are generally stored in rigid or semi-rigid vessels such as bottles, vials or otherwise in plastic bags, and these sometimes need to be transferred very carefully in order to avoid spillage of the liquid material as well as vapour thereof which can be detrimental for the health of medical stuff as well as the patient. Therefore, it has long been a challenge in the medical device sector to provide functionally improved and safe medical adapters and medication transfer devices with the objective of maximal sealing from the surroundings.
  • a fluid transfer device of the kind that has a piercing member enclosed in a protection chamber is disclosed in WO 2008/136720 A1 wherein first and second connection parts are rotatably engaged to each other in order to provide safer handling and administration of drugs and other medical substances.
  • This arrangement has several drawbacks in terms of safety, production and use.
  • the device for instance comprises several components slidable along an axis and rotatable in radial direction which apparently increase complexity and production costs.
  • the need to activate the device by movement in both longitudinal and radial directions increases also complexity of using the device, and this would be undesirable for the physician and nursing staff that usually prepare several doses in a day.
  • WO 03/086530 A1 A more simplified device for transferring of medicaments is disclosed in WO 03/086530 A1 wherein the device exhibits a first end and a second end for attachment to a bottle and infusion port, respectively.
  • This device however, is not suitable to be used with a syringe and it further suffers of several drawbacks because the device is still complicated with its telescopically arranged structure and is also lacking of a safety measure against unintentional exposure of the needle outside as well as leakage or spillage of the medical agent after removal of the device from the liquid transfer assembly.
  • EP 0 888 794 A2 discloses a fluid transfer device having an access cannula and blunt cannula wherein a spring means is provided for helping to position said access cannula within the passageway of the blunt cannula.
  • the spring means can be a coil spring or can be made of an elastic material which can seal, to a certain extent, surrounding of the cannula.
  • the fluid transfer device is nevertheless insufficient for satisfactory sealing at proximal end where access cannula is operated.
  • US 2013/0006200 A1 discloses a female piercing member protection device for connection with a male connection part in order to avoidance of undesired exposure to and leakage of hazardous medicaments, although the female part is always in need of being used together with the corresponding male part for safety concerns. Because the tip of the piercing member, i.e. the needle, is kept in between barriers of female and male parts in inactivated position, the female part per se is not suitable to be used alone, and therefore is not flexible enough to be used with different varieties of vessels, vials, plastic bags, adapters etc. Moreover, the device is still complicated enough in terms of use and production. The activated position, for instance can only be reached when the outer casing has been turned to a second position, and the connection member is moved along the longitudinal axis (A).
  • WO 96/00053 describes another fluid transfer device comprising a hollow piercing element
  • the present invention relates to a fluid transfer device (1) comprising an outer casing (6), a proximal end (8), a piercing member (3), a pierceable seal (4) arranged against said piercing member (3) and a distal end (D) with a number of locking members (5).
  • Said piercing member (3) that is partially held in a channel (2) extends from the proximal end (8) longitudinally through the distal end (D) to provide a fluid passageway therebetween in an activated position of the device (1).
  • the device (1) of the present invention further comprises a spring member (11) made of an elastic material extending from the proximal end (8) longitudinally through the distal end (D) in a manner surrounding the piercing member (3) in fluid tight fashion and forming an inner through channel (22) therein.
  • Said spring member (11) comprises an upper portion (12), a sealing portion (13), and a number of locking members (14) in close proximity to the said distal end (D), wherein said upper portion (12), sealing portion (13), and locking members (14) are integrally molded as a one piece unit.
  • Said upper portion (12) is flexible such that being movable between an activated position (dawn) and deactivated position (up).
  • Said locking members (14) comprise a claw like structure that is tightly squeezed around the surface to be connected in an activated position of the device (1).
  • the locking members (14) preferably comprise a ring shaped protrusion (21) surrounding, in horizontal direction, the said locking members (14).
  • the device (1) of the present invention has a hallow inner surface, and is preferably having groove (22) corresponding to the aforesaid protrusion (21). This groove (22) receives the protrusion (21) in a deactivated position of the device (1) as shown in Fig. 1 .
  • the protrusion (21) of the locking members (14) dismantles from the corresponding groove (22) causing an inwardly bending of the locking members (14) and providing a squeezing function.
  • the piercing member (3) is arranged in a position pricked within the pierceable seal (4) when the device (1) rests in a deactivated position.
  • the proximal end (8) of the device (1) is also configured to make a female connection with for instance an injection device, more particularly with a standard syringe device.
  • said flexible upper portion (12) is formed as a bellow which is advantageous for obtaining a more stable flexibility.
  • the sealing portion (13) of the spring member (11) comprises a seat for housing the pierceable seal (4) such that the piercing member (3) is isolated from outside within the through channel (23) of the spring member (11).
  • the present invention is disclosed in more detail with reference to different embodiments hereinbelow.
  • the invention is mainly directed to a fluid transfer device (1) in the form of an adapter which can be used for instance as a conduit in between several components known in the art, for instance syringes, vials, bottles, plastic bags, cannulas and various adapters used for transferring of liquids, more preferably of medicaments or any biological liquids from one storage medium to another.
  • the device according to the present invention is particularly suitable for use in transferring of hazardous medicaments or biologic material, exposure to which causes undesirable health risks in medical staff and patients.
  • the fluid transfer device (1) of the present invention comprises a tubular rigid casing (6) which optionally includes a clips (7) ( Fig. 9 ) for dismantling of the locking members (5) after the transferring operation.
  • Said clips (7) may be preferable as it helps easily to move away another device (e.g. vial, cannula, bottle or any adapter) after usage, and it also prevents unintentional detachment of the device (1) from another vial or adapter.
  • the fluid transfer device (1) of the current invention further comprises a proximal end (8) and a distal end (D) that provide fluid tight connection to other devices and vessels.
  • said proximal end (8) is of the type of a female connection part, preferably threaded in order to, for instance fixedly connect to an injection device (100) (e.g. syringe) as shown in Figure 2 .
  • an injection device e.g. syringe
  • this proximal end (8) may be adapted to make connection to any vial, syringe or adapter such that a fluid tight connection in transfer of fluid is achieved.
  • the spring member (11) itself surrounds the piercing member (3) such that it is isolated from casing (6) of the device (1) and is operated within the through channel (23) of the spring member (11).
  • Said spring member (11) mainly comprises an upper portion (12), a sealing portion (13) and a number of locking members (14) preferably in the form of claws.
  • the spring member (11) having the components above is made of an elastic material such as natural rubber, synthetic rubber or thermoplastic elastomer, but more preferably of thermoplastic polyurethane (TPU).
  • TPU thermoplastic polyurethane
  • the upper portion (12) extending longitudinally inside the casing (6) is preferably formed as a bellow which is found to be the most advantageous configuration for easy and stable movement of the device (1) during activation and deactivation positioning upon another device.
  • said upper portion (12), sealing portion (13) and the locking members (14) of the spring member (11) are integrally molded to have a one piece structure. This is not only advantageous for ease of manufacturing but also provides a perfectly sealed and safe arrangement during operation and post-operation of the device (1).
  • the spring member (11) remains unloaded.
  • Tip portion (9) of the piercing member (3) is also secured in deactivated position inside the through channel (23) of the spring member (11).
  • the tip portion (9) in this position is arranged to be pricked into the pierceable seal (4) that is placed in a sealing seat within the seal portion (13) of the spring member (11).
  • the details of the spring member (11) can be seen in detail in Figures 3a , 3b and 3c .
  • the spring member (11) of the current invention has a proximal end (19) having an enlarged width or radius compared to the upper portion (12) that enables fixation in between the needle holder (10) and casing (6) of the fluid transfer device (1). This is preferably the only fixation point of said spring member (11) inside the casing (6) which enables a very easy production procedure and avoidance of complicated components.
  • the fluid transfer device (1) may for instance be used in transferring of a liquid medicament from a vial (300) to an injection device (100) or vice versa, as shown in Figures 2 .
  • the proximal end (8) of the device (1) can be coupled to the injection device (100) while the distal end (D) is coupled to an adapter (200).
  • proximal end (8) of the fluid transfer device (1) can be adopted for connection to a tip portion of the conventional syringes which can be used as an injection device (100).
  • the fluid transfer device (1) of the current invention when placed on an adapter-vial arrangement, can be easily activated by a simple longitudinal force in which case a top portion or top sealing (204) of the adapter (200) abuts to the sealing portion (13) of the spring member (11) as well as to the pierceable sealing (4) located therein.
  • the spring member (11), particularly upper portion (12) thereof is loaded and compressed which eventually causes the piercing member (3) to move distally along the pierceable seal (4) and to be exposed through inside of the adapter (200) as shown in Fig. 2 .
  • both the locking members (14) of the spring member (11) and locking members (5) of the casing (6) are engaged to corresponding protrusions (202, 203) of the adapter (200) to provide a "double locking". Therefore, a perfectly secured arrangement is provided in a fluid tight manner by applying a force only in "one direction”.
  • the flow of the liquid from the vial (300) to the injection device (100) is illustrated in Fig. 4 .
  • the white arrows in this figure represent the air flow while the black arrows represent the liquid flow.
  • the cannula of the adapter (200) includes a liquid passageway (205) and air passageway (206) for transfer of the liquid through the device (1) properly.
  • the air supply means (207) can be of any type such as a filter type as in Fig. 7 , or a receptacle type as shown in Fig. 8 or a combination of both.
  • the receptacle types can be flexible (e.g. bellow) that contain prefilled clean air to be supplied into the vial (300) for purposes of pressure equalizing.
  • a filter type air supply means (207) is particularly preferred as it provides a more compact structure and practical use.
  • the filter can have apertures of 0.1 to 0.7 ⁇ m, more particularly of about 0.2 ⁇ m which can substantially clean the air from contaminants.
  • the device (1) can be deactivated and detached after completion of the fluid transfer similarly by applying an inverse longitudinal force only in one direction.
  • a clips (7) arrangement connected to the locking members (5) is used ( Fig. 9 )
  • the user may easily dismantle said locking members (5) via said clips (7), in which case said device (1) automatically turns into the normal position of Fig. 1 , without needing of any other rotational movement, where the piercing member (3) turns into a perfectly secured and sealed position.
  • distal end (D) of the fluid transfer device (1) according to the present invention is configured as a female connection part, and therefore locking members (14) of the spring member (11) are also arranged as a female connection part that provide an additional locking means (i.e. double locking) of the device (1).
  • the double locking can be realized upon the corresponding protrusions (202, 203) on an adapter or even on a vial.
  • the sealing portion (13) of the spring member (11) is provided with a special arrangement as shown in detail with Fig. 3c .
  • This arrangement mainly comprises an outer wall (17) and an inner wall (16) which are concentrically formed and having a spacing (15) therebetween.
  • the spacing (15) as mentioned herein is adapted to receive a corresponding protrusion (203) of an adapter or vial.
  • locking of an elastic member such as the locking members (14) of the spring member (11) according to this invention to a corresponding protrusion (203) of an adapter or vial could be problematic because the elastic claws would not be rigid enough to grip the said protrusion (203) which would likely result in a malfunction in terms of sealing and locking.
  • the present invention solves this additional problem by a specially arranged locking members (14) as an integral part of the spring member (11), comprising a ring shaped protrusion (21) that is normally accommodated in a corresponding groove (22) of the casing (6).
  • This arrangement advantageously enables the technical effect that once the device (1) is activated and spring member (11) is loaded, the protrusion (21) of the locking members (14) dismantles from the corresponding groove (22) and moves upwardly causing inwardly bending of the locking members (14) such that squeezing around the periphery of a male connection port (e.g. a collar or protrusion; 203) of another device.
  • a male connection port e.g. a collar or protrusion; 203
  • the longitudinal force causes the spring member (11) to be loaded and moved proximally in the direction of the proximal end (8), where in this instance the locking members (14) of the spring member (11) are squeezed to a certain extent in central direction.
  • a connection of this fashion constitutes a first locking which is also sealing an opening of the said male connection part, whereas the locking members (5) of the casing (6) provides an additional lock function on a corresponding protrusion (202).
  • the latter locking means fixes the overall device (1) to the adapter (200) or where appropriate to a vial (300) such that the loaded spring member (11) does not cause a detachment without intention of the user.
  • the device (1) of the current invention provides an excellent safety without needing extra locking means operated by complicated components and movement in different axis (i.e. transversally or radially).
  • the spring member (11) which acts also as a sealing around the piercing member (3) is also advantages even in malfunction of the pierceable seal (4) of the device (1). This is best illustrated in Figures 5 and 6 which show proper and malfunction states of the system, respectively. As can be seen in Fig. 6 , the spring member (11) successfully stores the liquid within the through channel (23) without any leakage to the casing (6).
  • the fluid transfer device (1) of the present invention is described in an exemplary system containing a vial (300), adapter (200) and an injection device (100), it can also be used in other systems, for instance for transferring of liquid medicament from a vial (300) to another vessel such as a plastic bag (400).
  • An adapter (500; 700) with two inlet ports can advantageously be used as shown in Figures 10 , 11 , 13 and 14 for transferring of a liquid into two different receptacles.
  • a medicament for instance can be transferred from a vial (300) to any receptacle such as a plastic bag as shown in the configuration of Figures 10 and 11 .
  • the adapter (500) is adapted to operate with one injection device (100) and two fluid transfer devices (1) according to the present invention.
  • the adapter (500) having two inlets can for instance be connected to the fluid transfer devices (1) via first and second ports (501, 502) with a luer lock connection style from the proximal ends (8) of the devices (1) wherein one of the devices (1) is connected to a vial (300) and the other is adapted to connect to a plastic bag (not shown) via a spike adapter (600).
  • any kind of adapter that is connected to the distal end (D) of the device (1) such as the one mentioned above is needed to have circumferential protrusions (602, 603) in order to achieve a "double locking" connection as identified in foregoing sections.
  • the first protrusion (602) is designed to engage with locking members (5) of the casing (6) and the other protrusion (603) is designed to engage with locking members (14) of the spring member (11).
  • a medicament in a vial (300) can be transferred into another receptacle (e.g. plastic bag) by drawing it firstly into the injection device (100) and then injecting the same through the adapter (500) to another fluid flow way without detachment of the any of the devices within the assembly.
  • the liquid medicament is transferred from the injection device (100) to a receptacle (400) (e.g. plastic bag) which release the said medicament in a predetermined dosage rate to a patient as shown in Fig. 13 .
  • a receptacle e.g. plastic bag
  • the dashed arrows show the direction of the fluid flow within this assembly. Accordingly a spike adapter (700) with two inlet ports as shown in Fig. 14 is used for this purpose.
  • Said adapter (700) may comprise a cannula (710) that is adapted to engage to a hose of the receptacle (400) while one of the ports (720) is also adapted to engage with the fluid transfer device (1) according to the present invention by way of locking to the protrusions (721, 722) provided circumferentially on the relevant port (720).
  • the other port (730) of the adapter (700) may be adapted to engage with a further port delivering the medicament to the patient.
  • the fluid transfer device (1) according to the present invention can be used with various fluid transfer systems including various components such as injection devices (100), vial adapters (200), adapters with two inlets (500, 700), and spike adapters (600).
  • various components such as injection devices (100), vial adapters (200), adapters with two inlets (500, 700), and spike adapters (600).
  • At least one adapter comprises a first circumferential protrusion (202; 602; 721) that is adapted to engage with locking members (5) of the casing (6), and a second circumferential protrusion (203; 603; 722) adapted to be engaged with locking members (14) of the spring member (11) at a distal end (D) of the fluid transfer device (1).
  • the kit of parts preferably contains an adapter (500; 700) with two inlet ports at least one port of which is adapted to be engaged in a double locking manner with the fluid transfer device (1) of the present invention.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (15)

  1. Flüssigkeitsübertragungsvorrichtung (1) mit einem äußeren Gehäuse (6), einem proximalen Ende (8), einem Durchstechelement (3), einer durchstechbaren Dichtung (4), die gegen das Durchstechelement (3) angeordnet ist, und einem distalen Ende (D) mit einer Anzahl von Verriegelungselementen (5); wobei sich das Durchstechelement (3) von dem proximalen Ende (8) in Längsrichtung durch das distale Ende (D) erstreckt, um in einer aktivierten Position der Vorrichtung (1) einen Flüssigkeitsdurchgang dazwischen zu schaffen;
    wobei die Vorrichtung (1) ferner ein Federelement (11) aus einem elastischen Material aufweist, das sich in einer das Durchstechelement (3) flüssigkeitsdicht umgebenden Weise von dem proximalen Ende (8) in Längsrichtung durch das distale Ende (D) erstreckt und in seinem Inneren einen inneren Durchgangskanal (23) bildet, wobei das Federelement (11) einen oberen Bereich (12), einen Dichtungsbereich (13) und eine Anzahl von Verriegelungselementen (14) in unmittelbarer Nähe zu dem genannten distalen Ende (D) aufweist, die in Form einer einstückigen Einheit in integraler Weise durch Formen gebildet sind; wobei der obere Bereich (12) flexibel ist, so dass er zwischen einer aktivierten Position und einer deaktivierten Position beweglich ist, und
    wobei die Vorrichtung (1) zwischen der aktiviertem und der deaktivierten Position betätigbar ist, wobei die Vorrichtung (1) durch eine Längskraft aktiviert wird, um das Federelement (11) zu spannen, wobei die Vorrichtung (1) eine Doppelverriegelung aufweist, indem sie die entsprechenden Vorsprünge an einem weiteren Fläschchen, Adapter oder Ventil mittels der Verriegelungselemente (5) des Gehäuses (6) und der Verriegelungselemente (14) des Federelements (11) umschließt.
  2. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei das Durchstechelement (3) in einer in die durchstechbare Dichtung (4) eingestochenen Position angeordnet ist, wenn sich die Vorrichtung (1) in einer deaktivierten Position befindet.
  3. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei das proximale Ende (8) der Vorrichtung (1) zum Herstellen einer aufnehmenden Verbindung ausgebildet ist.
  4. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei der flexible obere Bereich (12) als Faltenbalg ausgebildet ist.
  5. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei der Dichtungsbereich (13) des Federelements (11) einen Sitz zur derartigen Unterbringung der durchstechbaren Dichtung (4) aufweist, dass das Durchstechelement (3) innerhalb des Durchgangskanals (23) des Federelements (11) von der äußeren Umgebung isoliert ist.
  6. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei der Dichtungsbereich (13) in konzentrischer Ausbildung eine Innenwand (16) und eine Außenwand (17) aufweist, die dazwischen einen Abstand (15) bilden.
  7. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei die Verriegelungselemente (14) des Federelements (11) in Form von Klauen ausgebildet sind.
  8. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 7,
    wobei die Verriegelungselemente (14) des Federelements (11) einen ringförmigen umlaufenden Vorsprung (21) aufweisen und das äußere Gehäuse (6) eine den Vorsprung (21) aufnehmende Nut (22) aufweist, wobei der Vorsprung (21) in einer aktivierten Position der Vorrichtung (1) aus der entsprechenden Nut (22) entfernt ist und die Verriegelungselemente (14) dadurch nach innen gebogen sind, um die entsprechenden Vorsprünge an einem weiteren Fläschchen, Adapter oder Ventil mit Druck zu beaufschlagen.
  9. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei der obere Bereich (12) des Federelements (11) einen erweiterten Endbereich (19) aufweist, der zur Fixierung des Federelements (11) in der Flüssigkeitsübertragungsvorrichtung (1) zwischen dem äußeren Gehäuse (6) und einem Nadelhalter (10) festgelegt ist.
  10. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 3,
    wobei das proximale Ende (8) der Vorrichtung (1) zur Herstellung einer Luer-Verriegelung mit einer Injektionsvorrichtung (100) ausgebildet ist.
  11. Flüssigkeitsübertragungsvorrichtung (1) nach Anspruch 1,
    wobei das äußere Gehäuse (6) Klammern (7) aufweist, die den Verriegelungselementen (5) zugeordnet sind.
  12. Teilesatz, aufweisend:
    - eine Flüssigkeitsübertragungsvorrichtung (1) nach einem der vorhergehenden Ansprüche,
    - mindestens eine Injektionsvorrichtung (100), die dazu ausgebildet ist, in flüssigkeitsdichter Weise mit dem proximalen Ende (8) der Flüssigkeitsübertragungsvorrichtung (1) in Eingriff zu treten, und
    - mindestens einen Adapter (200, 500, 600, 700), der zur Ineingriffnahme mit der Flüssigkeitstransfervorrichtung (1) ausgebildet ist.
  13. Teilesatz nach Anspruch 12,
    wobei mindestens ein Adapter (200, 500, 600, 700) einen ersten umlaufenden Vorsprung aufweist (202; 602; 721) aufweist, der zur Ineingriffnahme mit Verriegelungselementen (5) des Gehäuses (6) ausgebildet ist, sowie einen zweiten umlaufenden Vorsprung (203; 603; 722) aufweist, der zur Ineingriffnahme mit Verriegelungselementen (14) des Federelements (11) an einem distalen Ende (D) der Flüssigkeitsübertragungsvorrichtung (1) ausgebildet ist.
  14. Teilesatz nach Anspruch 12,
    wobei der Teilesatz einen Adapter (500; 700) mit zwei Einlassöffnungen aufweist, wobei mindestens eine Öffnung davon dazu ausgebildet ist, mit der Flüssigkeitsübertragungsvorrichtung (1) in Doppelverriegelungsweise in Eingriff zu treten.
  15. Teilesatz nach Anspruch 14,
    wobei der Teilesatz einen Dorn-Adapter (600; 700) aufweist, der zur Ineingriffnahme mit einem Kunststoffbeutel ausgebildet ist, während mindestens eine Öffnung des Adapters (600; 700) dazu ausgebildet ist, mit der Flüssigkeitsübertragungsvorrichtung (1) in Doppelverriegelungsweise in Eingriff zu treten.
EP14151085.9A 2014-01-14 2014-01-14 Flüssigkeitsübertragungsvorrichtung mit durchstechelement Active EP2893916B1 (de)

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EP14151085.9A EP2893916B1 (de) 2014-01-14 2014-01-14 Flüssigkeitsübertragungsvorrichtung mit durchstechelement
PCT/TR2015/000026 WO2015108495A1 (en) 2014-01-14 2015-01-14 Fluid transfer device having a piercing member

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EP14151085.9A EP2893916B1 (de) 2014-01-14 2014-01-14 Flüssigkeitsübertragungsvorrichtung mit durchstechelement

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IL243108B (en) 2015-12-22 2018-08-30 Kriheli Marino Part of a friend
WO2019224372A1 (en) * 2018-05-25 2019-11-28 Becton Dickinson France Connector for connecting a medical injection device to a container
JP7504986B2 (ja) * 2019-07-24 2024-06-24 イネイブル インジェクションズ、インコーポレイテッド 医療用流体の注射と移送の装置および方法
CN115607445B (zh) * 2022-07-01 2024-03-01 广东健力源医疗科技有限公司 一种侧导管型全封闭式安全配药装置

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US2342215A (en) * 1942-08-03 1944-02-22 Harold N Perelson Dispensing and sealing stopper
US2667986A (en) * 1951-12-22 1954-02-02 Harold N Perelson Self-sealing dispensing device
DE3483475D1 (de) * 1983-05-20 1990-11-29 Bengt Gustavsson Anordnung zur uebertragung einer substanz.
US4895570A (en) 1987-06-05 1990-01-23 Abbott Laboratories Locking port shroud for peritoneal dialysis tubing connector
CA2001732A1 (en) 1988-10-31 1990-04-30 Lawrence A. Lynn Intravenous line coupling device
AU2945495A (en) * 1994-06-24 1996-01-19 Icu Medical, Inc. Fluid transfer device and method of use
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US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
EP3111911B1 (de) 2007-05-08 2018-10-17 Carmel Pharma AB Flüssigtransfervorrichtung
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
EP2231100B1 (de) 2008-01-17 2011-10-05 Teva Medical Ltd. Spritzenadapterelement in einem arznei-mischsystem
ES2447303T3 (es) 2008-12-15 2014-03-11 Carmel Pharma Ab Dispositivo de conector
WO2013119823A1 (en) 2012-02-07 2013-08-15 Yukon Medical, Llc Transfer device with fluid filter

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