EP2814773A4 - Appareil et procédé de mélange centrifuge microfluidique - Google Patents

Appareil et procédé de mélange centrifuge microfluidique

Info

Publication number
EP2814773A4
EP2814773A4 EP13749704.6A EP13749704A EP2814773A4 EP 2814773 A4 EP2814773 A4 EP 2814773A4 EP 13749704 A EP13749704 A EP 13749704A EP 2814773 A4 EP2814773 A4 EP 2814773A4
Authority
EP
European Patent Office
Prior art keywords
mixing apparatus
microfluidic mixing
centrifugal microfluidic
centrifugal
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP13749704.6A
Other languages
German (de)
English (en)
Other versions
EP2814773B1 (fr
EP2814773A1 (fr
Inventor
Liviu Clime
Teodor Veres
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
National Research Council of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada filed Critical National Research Council of Canada
Publication of EP2814773A1 publication Critical patent/EP2814773A1/fr
Publication of EP2814773A4 publication Critical patent/EP2814773A4/fr
Application granted granted Critical
Publication of EP2814773B1 publication Critical patent/EP2814773B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/423—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components
    • B01F25/4231—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components using baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B7/00—Microstructural systems; Auxiliary parts of microstructural devices or systems
EP13749704.6A 2012-02-16 2013-02-18 Appareil et procédé de mélange centrifuge microfluidique Active EP2814773B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261599647P 2012-02-16 2012-02-16
PCT/CA2013/000139 WO2013120190A1 (fr) 2012-02-16 2013-02-18 Appareil et procédé de mélange centrifuge microfluidique

Publications (3)

Publication Number Publication Date
EP2814773A1 EP2814773A1 (fr) 2014-12-24
EP2814773A4 true EP2814773A4 (fr) 2015-10-28
EP2814773B1 EP2814773B1 (fr) 2017-05-31

Family

ID=48983493

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13749704.6A Active EP2814773B1 (fr) 2012-02-16 2013-02-18 Appareil et procédé de mélange centrifuge microfluidique

Country Status (6)

Country Link
US (1) US9555382B2 (fr)
EP (1) EP2814773B1 (fr)
AU (1) AU2013220890B2 (fr)
CA (1) CA2864641C (fr)
ES (1) ES2635549T3 (fr)
WO (1) WO2013120190A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1894617B1 (fr) * 2006-08-31 2013-08-14 Samsung Electronics Co., Ltd. Procédé de mélange d'au moins deux types de fluides dans un substrat de traitement de microfluide à centrifuge
AU2013220890B2 (en) * 2012-02-16 2016-03-10 National Research Council Of Canada Centrifugal microfluidic mixing apparatus and method
DE102012202775B4 (de) * 2012-02-23 2016-08-25 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Fluidikmodul, vorrichtung und verfahren zum pumpen einer flüssigkeit
EP3114454B1 (fr) 2014-03-07 2021-05-26 National Research Council of Canada Micro-contrôleur pour dispositifs microfluidiques centrifuges
US11071985B2 (en) 2014-05-26 2021-07-27 National Research Council Of Canada Swivel mount for centrifugal microfluidic chip
DE102014224664B3 (de) * 2014-12-02 2015-10-08 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und verfahren zur tropfenerzeugung
CA3142903A1 (fr) * 2019-06-28 2020-12-30 National Research Council Of Canada Puce microfluidique centrifuge, kit et systeme d'alimentation en gaz sur puce
US11938480B2 (en) 2020-05-14 2024-03-26 The Board Of Trustees Of The University Of Illinois Urbana, Illinois Microfluidic diagnostic device with a three-dimensional (3D) flow architecture
TWI801303B (zh) * 2021-08-12 2023-05-01 中央研究院 具有三度空間混合效果的微流混合器

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US3829223A (en) * 1973-07-20 1974-08-13 Atomic Energy Commission Mixing rotor for fast analyzer of rotary cuvette type with means for enhancing the mixing of sample and reagent liquids
FR2409514A1 (fr) * 1977-11-17 1979-06-15 Bretaudiere Jean Pierre Perfectionnement aux appareils d'analyse par centrifugation
DE3044385A1 (de) * 1980-11-25 1982-06-24 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes rotoreinsatzelement
DE3633343A1 (de) 1986-09-10 1988-03-17 Bayer Ag Verfahren und vorrichtung zum herstellen eines kunststoff, insbesondere schaumstoff bildenden, fliessfaehigen reaktionsgemisches aus mindestens zwei fliessfaehigen reaktionskomponenten im durchlauf
DE19604289C2 (de) 1996-02-07 1998-04-23 Danfoss As Mikromischer
US5826981A (en) 1996-08-26 1998-10-27 Nova Biomedical Corporation Apparatus for mixing laminar and turbulent flow streams
PT1272268E (pt) 2000-03-02 2012-07-24 Dow Global Technologies Llc Reator tubular, processo de realização de reações multifásicas líquido/ líquido num reator tubular, e um processo de nitração cíclica de compostos aromáticos num reator tubular
US6994749B2 (en) 2001-06-08 2006-02-07 Syrrx, Inc. Microfluidic device for parallel delivery and mixing of fluids
WO2003085379A2 (fr) * 2002-04-01 2003-10-16 Fluidigm Corporation Systemes d'analyse de particules microfluidiques
WO2004029221A2 (fr) * 2002-09-27 2004-04-08 The General Hospital Corporation Dispositif microfluidique pour la separation de cellules et utilisations de ce dispositif
US6916113B2 (en) * 2003-05-16 2005-07-12 Agilent Technologies, Inc. Devices and methods for fluid mixing
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
EP1874920A4 (fr) * 2005-04-05 2009-11-04 Cellpoint Diagnostics Dispositifs et procédés permettant d'enrichir et de modifier des cellules tumorales circulantes et d'autres particules
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EP2530168B1 (fr) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Dispositifs microfluidiques
EP1894617B1 (fr) * 2006-08-31 2013-08-14 Samsung Electronics Co., Ltd. Procédé de mélange d'au moins deux types de fluides dans un substrat de traitement de microfluide à centrifuge
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AU2013220890B2 (en) * 2012-02-16 2016-03-10 National Research Council Of Canada Centrifugal microfluidic mixing apparatus and method

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BURGER R ET AL: "Droplet Mixer based on Siphon-Induced Flow Discretization and Phase Shifting", MICRO ELECTRO MECHANICAL SYSTEMS, 2009. MEMS 2009. IEEE 22ND INTERNATIONAL CONFERENCE ON, IEEE, PISCATAWAY, NJ, USA, 25 January 2009 (2009-01-25), pages 443 - 446, XP031444325, ISBN: 978-1-4244-2977-6 *

Also Published As

Publication number Publication date
CA2864641A1 (fr) 2013-08-22
EP2814773B1 (fr) 2017-05-31
ES2635549T3 (es) 2017-10-04
EP2814773A1 (fr) 2014-12-24
US20150138912A1 (en) 2015-05-21
WO2013120190A1 (fr) 2013-08-22
AU2013220890A1 (en) 2014-10-02
AU2013220890B2 (en) 2016-03-10
US9555382B2 (en) 2017-01-31
CA2864641C (fr) 2021-05-04

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