EP2785250A4 - System and method useful for sarcomere imaging via objective-based microscopy - Google Patents

System and method useful for sarcomere imaging via objective-based microscopy

Info

Publication number
EP2785250A4
EP2785250A4 EP12853081.3A EP12853081A EP2785250A4 EP 2785250 A4 EP2785250 A4 EP 2785250A4 EP 12853081 A EP12853081 A EP 12853081A EP 2785250 A4 EP2785250 A4 EP 2785250A4
Authority
EP
European Patent Office
Prior art keywords
sarcomere
method useful
imaging via
via objective
based microscopy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12853081.3A
Other languages
German (de)
French (fr)
Other versions
EP2785250A1 (en
Inventor
Gabriel Nestor Sanchez
Scott L Delp
Mark J Schnitzer
Michael E Llewellyn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Priority to EP20199801.0A priority Critical patent/EP3847968A1/en
Publication of EP2785250A1 publication Critical patent/EP2785250A1/en
Publication of EP2785250A4 publication Critical patent/EP2785250A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0044—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4519—Muscles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/26—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes using light guides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A61B5/6857—Catheters with a distal pigtail shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A61B5/6859—Catheters with multiple distal splines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Astronomy & Astrophysics (AREA)
  • Cardiology (AREA)
  • Dentistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Endoscopes (AREA)
EP12853081.3A 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy Withdrawn EP2785250A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP20199801.0A EP3847968A1 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161564143P 2011-11-28 2011-11-28
PCT/US2012/066860 WO2013082156A1 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP20199801.0A Division EP3847968A1 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy

Publications (2)

Publication Number Publication Date
EP2785250A1 EP2785250A1 (en) 2014-10-08
EP2785250A4 true EP2785250A4 (en) 2015-07-29

Family

ID=48536014

Family Applications (2)

Application Number Title Priority Date Filing Date
EP20199801.0A Pending EP3847968A1 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy
EP12853081.3A Withdrawn EP2785250A4 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP20199801.0A Pending EP3847968A1 (en) 2011-11-28 2012-11-28 System and method useful for sarcomere imaging via objective-based microscopy

Country Status (2)

Country Link
EP (2) EP3847968A1 (en)
WO (1) WO2013082156A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8068899B2 (en) 2007-07-03 2011-11-29 The Board Of Trustees Of The Leland Stanford Junior University Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle
GB201315093D0 (en) * 2013-08-23 2013-10-09 Univ St Andrews Muscle contraction sensor
ITTO20131059A1 (en) 2013-12-23 2015-06-24 Fond Istituto Italiano Di Tecnologia INTEGRATED OPTICAL SYSTEM FOR A MICROENDOSCOPIC EQUIPMENT.
US10016136B2 (en) 2014-06-20 2018-07-10 Optomak, Inc. Image relaying cannula with detachable self-aligning connector
CA3016468A1 (en) 2016-03-08 2017-09-14 Zebra Medical Technologies, Inc. Non-invasive detection of skin disease
WO2018201082A1 (en) 2017-04-28 2018-11-01 Zebra Medical Technologies, Inc. Systems and methods for imaging and measurement of sarcomeres
CN109633885A (en) * 2019-01-29 2019-04-16 清华大学 Gradient-index lens micro imaging system and method based on focusing wavefronts
CN109674438B (en) * 2019-01-31 2024-02-27 北京超维景生物科技有限公司 Objective lens adjustable cavity endoscope detection device and laser scanning cavity endoscope

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US4598715A (en) * 1982-04-29 1986-07-08 Carl-Zeiss-Stiftung Instrument for spectral measurement in the bloodstream
EP0594388A1 (en) * 1992-10-19 1994-04-27 Hamamatsu Photonics K.K. Observing device
US20030031410A1 (en) * 2001-08-08 2003-02-13 Schnitzer Mark J. Multi-photon endoscopy
US20040260148A1 (en) * 2003-06-20 2004-12-23 Schnitzer Mark J. Multi-photon endoscopic imaging system
US20070057211A1 (en) * 2005-05-25 2007-03-15 Karsten Bahlman Multifocal imaging systems and method
US20090012406A1 (en) * 2007-07-03 2009-01-08 Llewellyn Michael E Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle
US20110152744A1 (en) * 2009-12-17 2011-06-23 Korea Advanced Institute Of Science And Technology Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same

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US5181511A (en) 1991-10-21 1993-01-26 Telectronics Pacing Systems, Inc. Apparatus and method for antitachycardia pacing using a virtual electrode
US5929985A (en) 1997-03-18 1999-07-27 Sandia Corporation Multispectral imaging probe
US6208886B1 (en) 1997-04-04 2001-03-27 The Research Foundation Of City College Of New York Non-linear optical tomography of turbid media
AU3970799A (en) 1998-05-04 1999-11-23 Board Of Regents Combined fluorescence and reflectance spectroscopy
US6639674B2 (en) 2000-03-28 2003-10-28 Board Of Regents, The University Of Texas System Methods and apparatus for polarized reflectance spectroscopy
JP4845318B2 (en) 2000-03-28 2011-12-28 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Method and apparatus for diagnostic multispectral digital imaging
US6542665B2 (en) 2001-02-17 2003-04-01 Lucent Technologies Inc. GRIN fiber lenses
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FR2834348B1 (en) 2001-12-28 2004-02-27 Mauna Kea Technologies MINIATURIZED FOCUSING OPTICAL HEAD, ESPECIALLY FOR AN ENDOSCOPE
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FR2842407B1 (en) 2002-07-18 2005-05-06 Mauna Kea Technologies "METHOD AND APPARATUS OF FIBROUS CONFOCAL FLUORESCENCE IMAGING"
US20040143190A1 (en) 2003-01-22 2004-07-22 Schnitzer Mark J. Mapping neural and muscular electrical activity
FR2877103B1 (en) * 2004-10-22 2012-02-10 Mauna Kea Technologies SYSTEM AND METHOD FOR FIBER MULTIPHOTONIC MICROSCOPIC IMAGING OF A SAMPLE
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4598715A (en) * 1982-04-29 1986-07-08 Carl-Zeiss-Stiftung Instrument for spectral measurement in the bloodstream
EP0594388A1 (en) * 1992-10-19 1994-04-27 Hamamatsu Photonics K.K. Observing device
US20030031410A1 (en) * 2001-08-08 2003-02-13 Schnitzer Mark J. Multi-photon endoscopy
US20040260148A1 (en) * 2003-06-20 2004-12-23 Schnitzer Mark J. Multi-photon endoscopic imaging system
US20070057211A1 (en) * 2005-05-25 2007-03-15 Karsten Bahlman Multifocal imaging systems and method
US20090012406A1 (en) * 2007-07-03 2009-01-08 Llewellyn Michael E Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle
US20110152744A1 (en) * 2009-12-17 2011-06-23 Korea Advanced Institute Of Science And Technology Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same

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ASHKAN MONFARED ET AL: "In Vivo Imaging of Mammalian Cochlear Blood Flow Using Fluorescence Microendoscopy", OTOLOGY & NEUROTOLOGY, vol. 27, no. 2, 1 February 2006 (2006-02-01), pages 144 - 152, XP055197023, ISSN: 1531-7129, DOI: 10.1097/01.mao.0000190708.44067.b0 *
BENJAMIN A. FLUSBERG ET AL: "In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope", OPTICS LETTERS, vol. 30, no. 17, 1 January 2005 (2005-01-01), pages 2272, XP055197027, ISSN: 0146-9592, DOI: 10.1364/OL.30.002272 *
See also references of WO2013082156A1 *

Also Published As

Publication number Publication date
WO2013082156A1 (en) 2013-06-06
EP2785250A1 (en) 2014-10-08
EP3847968A1 (en) 2021-07-14

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Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO

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Inventor name: LLEWELLYN, MICHAEL, E.

Inventor name: SANCHEZ, GABRIEL, NESTOR

Inventor name: SCHNITZER, MARK, J.

Inventor name: DELP, SCOTT, L.

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