EP2785250A4 - System und verfahren zur sarkomerdarstellung durch objektivbasierte mikroskopie - Google Patents
System und verfahren zur sarkomerdarstellung durch objektivbasierte mikroskopieInfo
- Publication number
- EP2785250A4 EP2785250A4 EP12853081.3A EP12853081A EP2785250A4 EP 2785250 A4 EP2785250 A4 EP 2785250A4 EP 12853081 A EP12853081 A EP 12853081A EP 2785250 A4 EP2785250 A4 EP 2785250A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- sarcomere
- method useful
- imaging via
- via objective
- based microscopy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000003384 imaging method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000386 microscopy Methods 0.000 title 1
- 210000002235 sarcomere Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0044—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4519—Muscles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/26—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes using light guides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
- A61B5/6857—Catheters with a distal pigtail shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
- A61B5/6859—Catheters with multiple distal splines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Astronomy & Astrophysics (AREA)
- Cardiology (AREA)
- Dentistry (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Endoscopes (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20199801.0A EP3847968A1 (de) | 2011-11-28 | 2012-11-28 | System und verfahren zur sarkomerbildgebung durch objektivbasierte mikroskopie |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161564143P | 2011-11-28 | 2011-11-28 | |
PCT/US2012/066860 WO2013082156A1 (en) | 2011-11-28 | 2012-11-28 | System and method useful for sarcomere imaging via objective-based microscopy |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20199801.0A Division EP3847968A1 (de) | 2011-11-28 | 2012-11-28 | System und verfahren zur sarkomerbildgebung durch objektivbasierte mikroskopie |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2785250A1 EP2785250A1 (de) | 2014-10-08 |
EP2785250A4 true EP2785250A4 (de) | 2015-07-29 |
Family
ID=48536014
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20199801.0A Pending EP3847968A1 (de) | 2011-11-28 | 2012-11-28 | System und verfahren zur sarkomerbildgebung durch objektivbasierte mikroskopie |
EP12853081.3A Withdrawn EP2785250A4 (de) | 2011-11-28 | 2012-11-28 | System und verfahren zur sarkomerdarstellung durch objektivbasierte mikroskopie |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20199801.0A Pending EP3847968A1 (de) | 2011-11-28 | 2012-11-28 | System und verfahren zur sarkomerbildgebung durch objektivbasierte mikroskopie |
Country Status (2)
Country | Link |
---|---|
EP (2) | EP3847968A1 (de) |
WO (1) | WO2013082156A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8068899B2 (en) | 2007-07-03 | 2011-11-29 | The Board Of Trustees Of The Leland Stanford Junior University | Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle |
GB201315093D0 (en) * | 2013-08-23 | 2013-10-09 | Univ St Andrews | Muscle contraction sensor |
ITTO20131059A1 (it) | 2013-12-23 | 2015-06-24 | Fond Istituto Italiano Di Tecnologia | Sistema ottico integrato per un'apparecchiatura microendoscopica. |
US10016136B2 (en) | 2014-06-20 | 2018-07-10 | Optomak, Inc. | Image relaying cannula with detachable self-aligning connector |
CA3016468A1 (en) | 2016-03-08 | 2017-09-14 | Zebra Medical Technologies, Inc. | Non-invasive detection of skin disease |
WO2018201082A1 (en) | 2017-04-28 | 2018-11-01 | Zebra Medical Technologies, Inc. | Systems and methods for imaging and measurement of sarcomeres |
CN109633885A (zh) * | 2019-01-29 | 2019-04-16 | 清华大学 | 基于波前聚焦的梯度折射率透镜显微成像系统及方法 |
CN109674438B (zh) * | 2019-01-31 | 2024-02-27 | 北京超维景生物科技有限公司 | 物镜可调节的腔体内窥镜探测装置及激光扫描腔体内窥镜 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4598715A (en) * | 1982-04-29 | 1986-07-08 | Carl-Zeiss-Stiftung | Instrument for spectral measurement in the bloodstream |
EP0594388A1 (de) * | 1992-10-19 | 1994-04-27 | Hamamatsu Photonics K.K. | Beobachtungsvorrichtung |
US20030031410A1 (en) * | 2001-08-08 | 2003-02-13 | Schnitzer Mark J. | Multi-photon endoscopy |
US20040260148A1 (en) * | 2003-06-20 | 2004-12-23 | Schnitzer Mark J. | Multi-photon endoscopic imaging system |
US20070057211A1 (en) * | 2005-05-25 | 2007-03-15 | Karsten Bahlman | Multifocal imaging systems and method |
US20090012406A1 (en) * | 2007-07-03 | 2009-01-08 | Llewellyn Michael E | Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle |
US20110152744A1 (en) * | 2009-12-17 | 2011-06-23 | Korea Advanced Institute Of Science And Technology | Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2189298A (en) * | 1936-04-09 | 1940-02-06 | Opticolor Ag | Optical system |
US5161063A (en) | 1991-02-21 | 1992-11-03 | University Of Rochester | Objectives for an optical data storage head |
US5181511A (en) | 1991-10-21 | 1993-01-26 | Telectronics Pacing Systems, Inc. | Apparatus and method for antitachycardia pacing using a virtual electrode |
US5929985A (en) | 1997-03-18 | 1999-07-27 | Sandia Corporation | Multispectral imaging probe |
US6208886B1 (en) | 1997-04-04 | 2001-03-27 | The Research Foundation Of City College Of New York | Non-linear optical tomography of turbid media |
AU3970799A (en) | 1998-05-04 | 1999-11-23 | Board Of Regents | Combined fluorescence and reflectance spectroscopy |
US6639674B2 (en) | 2000-03-28 | 2003-10-28 | Board Of Regents, The University Of Texas System | Methods and apparatus for polarized reflectance spectroscopy |
JP4845318B2 (ja) | 2000-03-28 | 2011-12-28 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 診断用マルチスペクトルデジタル画像化のための方法および装置 |
US6542665B2 (en) | 2001-02-17 | 2003-04-01 | Lucent Technologies Inc. | GRIN fiber lenses |
WO2003023479A1 (en) | 2001-09-07 | 2003-03-20 | Board Of Regents, The University Of Texas System | Multimodal miniature microscope |
US6643071B2 (en) | 2001-12-21 | 2003-11-04 | Lucent Technologies Inc. | Graded-index lens microscopes |
FR2834348B1 (fr) | 2001-12-28 | 2004-02-27 | Mauna Kea Technologies | Tete optique de focalisation miniaturisee, notamment pour endoscope |
FR2842628B1 (fr) | 2002-07-18 | 2004-09-24 | Mauna Kea Technologies | "procede de traitement d'une image acquise au moyen d'un guide compose d'une pluralite de fibres optiques" |
FR2842407B1 (fr) | 2002-07-18 | 2005-05-06 | Mauna Kea Technologies | "procede et appareillage d'imagerie de fluorescence confocale fibree" |
US20040143190A1 (en) | 2003-01-22 | 2004-07-22 | Schnitzer Mark J. | Mapping neural and muscular electrical activity |
FR2877103B1 (fr) * | 2004-10-22 | 2012-02-10 | Mauna Kea Technologies | Systeme et procede d'imagerie microscopique multiphotonique fibre d'un echantillon |
WO2006133509A1 (en) * | 2005-06-16 | 2006-12-21 | Swinburne University Of Technology | Imaging system |
FR2906898B1 (fr) * | 2006-10-05 | 2009-01-23 | Commissariat Energie Atomique | Dispositif de compensation ajustable de retard pupillaire. |
EP1998202B1 (de) * | 2007-06-01 | 2013-12-18 | STMicroelectronics (Grenoble) SAS | Bewegliche Linseneinheit mit Detektionsvorrichtung |
EP3479753B1 (de) * | 2008-03-19 | 2020-05-13 | Carl Zeiss Meditec AG | Chirurgisches mikroskopiesystem mit optischer kohärenz-tomografieeinrichtung |
US7869139B2 (en) * | 2008-10-30 | 2011-01-11 | Infinity Photo Optical | Modular afocal variator optical system providing focus with constant magnification |
US20120140302A1 (en) * | 2009-09-03 | 2012-06-07 | University Of Florida Research Foundation, Incorpo | Mems-based optical image scanning apparatus, methods, and systems |
US8134719B2 (en) * | 2010-03-19 | 2012-03-13 | Carestream Health, Inc. | 3-D imaging using telecentric defocus |
-
2012
- 2012-11-28 EP EP20199801.0A patent/EP3847968A1/de active Pending
- 2012-11-28 EP EP12853081.3A patent/EP2785250A4/de not_active Withdrawn
- 2012-11-28 WO PCT/US2012/066860 patent/WO2013082156A1/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4598715A (en) * | 1982-04-29 | 1986-07-08 | Carl-Zeiss-Stiftung | Instrument for spectral measurement in the bloodstream |
EP0594388A1 (de) * | 1992-10-19 | 1994-04-27 | Hamamatsu Photonics K.K. | Beobachtungsvorrichtung |
US20030031410A1 (en) * | 2001-08-08 | 2003-02-13 | Schnitzer Mark J. | Multi-photon endoscopy |
US20040260148A1 (en) * | 2003-06-20 | 2004-12-23 | Schnitzer Mark J. | Multi-photon endoscopic imaging system |
US20070057211A1 (en) * | 2005-05-25 | 2007-03-15 | Karsten Bahlman | Multifocal imaging systems and method |
US20090012406A1 (en) * | 2007-07-03 | 2009-01-08 | Llewellyn Michael E | Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle |
US20110152744A1 (en) * | 2009-12-17 | 2011-06-23 | Korea Advanced Institute Of Science And Technology | Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same |
Non-Patent Citations (3)
Title |
---|
ASHKAN MONFARED ET AL: "In Vivo Imaging of Mammalian Cochlear Blood Flow Using Fluorescence Microendoscopy", OTOLOGY & NEUROTOLOGY, vol. 27, no. 2, 1 February 2006 (2006-02-01), pages 144 - 152, XP055197023, ISSN: 1531-7129, DOI: 10.1097/01.mao.0000190708.44067.b0 * |
BENJAMIN A. FLUSBERG ET AL: "In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope", OPTICS LETTERS, vol. 30, no. 17, 1 January 2005 (2005-01-01), pages 2272, XP055197027, ISSN: 0146-9592, DOI: 10.1364/OL.30.002272 * |
See also references of WO2013082156A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013082156A1 (en) | 2013-06-06 |
EP2785250A1 (de) | 2014-10-08 |
EP3847968A1 (de) | 2021-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20140623 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: LLEWELLYN, MICHAEL, E. Inventor name: SANCHEZ, GABRIEL, NESTOR Inventor name: SCHNITZER, MARK, J. Inventor name: DELP, SCOTT, L. |
|
DAX | Request for extension of the european patent (deleted) | ||
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20150701 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61B 6/00 20060101AFI20150625BHEP |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
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17Q | First examination report despatched |
Effective date: 20161124 |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20201007 |