EP2755687A4 - ANTIBODY RECOGNIZING AN EPITOPE ARBITRAIRED WITH AT LEAST THREE AMINO ACID RESIDUES IN A PEPTIDE, AND GENERATING METHOD THEREOF - Google Patents

ANTIBODY RECOGNIZING AN EPITOPE ARBITRAIRED WITH AT LEAST THREE AMINO ACID RESIDUES IN A PEPTIDE, AND GENERATING METHOD THEREOF

Info

Publication number
EP2755687A4
EP2755687A4 EP12832007.4A EP12832007A EP2755687A4 EP 2755687 A4 EP2755687 A4 EP 2755687A4 EP 12832007 A EP12832007 A EP 12832007A EP 2755687 A4 EP2755687 A4 EP 2755687A4
Authority
EP
European Patent Office
Prior art keywords
peptide
generating
amino acid
acid residues
antibody recognizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12832007.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2755687A2 (en
Inventor
Zhiwei Wu
Xilin Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Y-Clone Medical Sciences Co Ltd
Original Assignee
SUZHOU NAAO NEW MATERIAL SCIENCES Co Ltd
SUZHOU NAAO NEW MATERIAL SCIENCES CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SUZHOU NAAO NEW MATERIAL SCIENCES Co Ltd, SUZHOU NAAO NEW MATERIAL SCIENCES CO Ltd filed Critical SUZHOU NAAO NEW MATERIAL SCIENCES Co Ltd
Publication of EP2755687A2 publication Critical patent/EP2755687A2/en
Publication of EP2755687A4 publication Critical patent/EP2755687A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP12832007.4A 2011-09-17 2012-09-17 ANTIBODY RECOGNIZING AN EPITOPE ARBITRAIRED WITH AT LEAST THREE AMINO ACID RESIDUES IN A PEPTIDE, AND GENERATING METHOD THEREOF Withdrawn EP2755687A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161535988P 2011-09-17 2011-09-17
PCT/US2012/055771 WO2013040564A2 (en) 2011-09-17 2012-09-17 Antibody recognizing arbitrarily designed epitope of three or more amino acid residues in a peptide and method of generating thereof

Publications (2)

Publication Number Publication Date
EP2755687A2 EP2755687A2 (en) 2014-07-23
EP2755687A4 true EP2755687A4 (en) 2015-04-08

Family

ID=47884023

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12832007.4A Withdrawn EP2755687A4 (en) 2011-09-17 2012-09-17 ANTIBODY RECOGNIZING AN EPITOPE ARBITRAIRED WITH AT LEAST THREE AMINO ACID RESIDUES IN A PEPTIDE, AND GENERATING METHOD THEREOF

Country Status (7)

Country Link
EP (1) EP2755687A4 (zh)
JP (2) JP2014527085A (zh)
CN (1) CN104039350B (zh)
AU (2) AU2012308212A1 (zh)
CA (1) CA2855781A1 (zh)
HK (1) HK1200359A1 (zh)
WO (1) WO2013040564A2 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10245313B2 (en) * 2014-10-24 2019-04-02 Versitech Limited DNA motif compounds and methods for inducing specific antibodies and cellular immunity
CN111153996B (zh) * 2020-01-10 2021-12-14 苏州睿瀛生物技术有限公司 G蛋白偶联受体的抗体及其制备方法和g蛋白偶联受体试剂盒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0725838A4 (en) * 1993-10-26 1997-02-26 United Biomedical Inc STRUCTURED SYNTHETIC ANTIGAN BANKS AS DIAGNOSTICS, VACCINE AND THERAPEUTIC AGENTS
WO1995011701A1 (en) * 1993-10-26 1995-05-04 Syntello, Inc. Inhibition of hiv mucosal infection
US6441140B1 (en) * 1998-09-04 2002-08-27 Cell Signaling Technology, Inc. Production of motif-specific and context-independent antibodies using peptide libraries as antigens
US9289487B2 (en) * 1999-09-14 2016-03-22 Antigen Express, Inc. II-key/antigenic epitope hybrid peptide vaccines
FR2809402A1 (fr) * 2000-05-26 2001-11-30 Dev Des Antigenes Combinatoire Bibliotheques peptidiques combinatoires convergentes et leur application a la vaccination contre le virus de l'hepatite c
WO2005074579A2 (en) * 2004-02-02 2005-08-18 Mixture Sciences, Inc. Peptide mixtures with immunomodulatory activity
US20100215695A1 (en) * 2007-10-09 2010-08-26 Technologie Integrale Limited Hiv preventive vaccine based on hiv specific antibodies

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CLAUDIA CHARLES-NIÑO ET AL: "Variable epitope libraries: New vaccine immunogens capable of inducing broad human immunodeficiency virus type 1-neutralizing antibody response", VACCINE, vol. 29, no. 32, 1 July 2011 (2011-07-01), pages 5313 - 5321, XP055172207, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2011.05.007 *
JAVAHERIAN K ET AL: "PRINCIPAL NEUTRALIZING DOMAIN OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 ENVELOPE PROTEIN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, US, vol. 86, no. 17, 1 September 1989 (1989-09-01), pages 6768 - 6772, XP000068860, ISSN: 0027-8424, DOI: 10.1073/PNAS.86.17.6768 *
PEDROZA-ROLDAN C ET AL: "Variable epitope library-based vaccines: Shooting moving targets", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 47, no. 2-3, 1 December 2009 (2009-12-01), pages 270 - 282, XP026886945, ISSN: 0161-5890, [retrieved on 20091023], DOI: 10.1016/J.MOLIMM.2009.09.024 *
See also references of WO2013040564A2 *

Also Published As

Publication number Publication date
AU2017251715A1 (en) 2017-11-09
AU2012308212A1 (en) 2014-03-27
CA2855781A1 (en) 2013-03-21
WO2013040564A3 (en) 2013-06-27
HK1200359A1 (zh) 2015-08-07
JP2014527085A (ja) 2014-10-09
WO2013040564A2 (en) 2013-03-21
CN104039350B (zh) 2019-07-05
CN104039350A (zh) 2014-09-10
JP2017141291A (ja) 2017-08-17
EP2755687A2 (en) 2014-07-23

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