EP2698634A4 - Biomarker for breast cancer - Google Patents
Biomarker for breast cancerInfo
- Publication number
- EP2698634A4 EP2698634A4 EP12770851.9A EP12770851A EP2698634A4 EP 2698634 A4 EP2698634 A4 EP 2698634A4 EP 12770851 A EP12770851 A EP 12770851A EP 2698634 A4 EP2698634 A4 EP 2698634A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- biomarker
- breast cancer
- breast
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011091378 | 2011-04-15 | ||
PCT/JP2012/060114 WO2012141285A1 (en) | 2011-04-15 | 2012-04-13 | Biomarker for breast cancer |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2698634A1 EP2698634A1 (en) | 2014-02-19 |
EP2698634A4 true EP2698634A4 (en) | 2014-11-26 |
EP2698634B1 EP2698634B1 (en) | 2017-11-08 |
Family
ID=47009444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12770851.9A Active EP2698634B1 (en) | 2011-04-15 | 2012-04-13 | Biomarker for breast cancer |
Country Status (7)
Country | Link |
---|---|
US (1) | US9618512B2 (en) |
EP (1) | EP2698634B1 (en) |
JP (1) | JP6075881B2 (en) |
KR (1) | KR101976219B1 (en) |
CN (1) | CN103547923B (en) |
ES (1) | ES2656988T3 (en) |
WO (1) | WO2012141285A1 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103808937B (en) * | 2014-03-13 | 2015-11-18 | 广州恒泰生物科技有限公司 | For breast cancer early metaphase quick diagnosis reagent kit and detection method thereof |
US20150285803A1 (en) * | 2014-04-08 | 2015-10-08 | Invivis Pharmaceuticals Inc. | Systems and methods for identifying progesterone receptor subtypes |
KR20170084086A (en) | 2014-11-17 | 2017-07-19 | 아르노 테라퓨틱스 인코포레이티드 | Onapristone extended-release compositions and methods |
CN105934672A (en) * | 2014-12-22 | 2016-09-07 | J制药股份有限公司 | circulating biomarker for cancer |
JP2018528944A (en) | 2015-09-25 | 2018-10-04 | コンテクスト バイオファーマ インコーポレイテッド | Method for producing onapristone intermediate |
JP6599710B2 (en) * | 2015-09-29 | 2019-10-30 | 公益財団法人ヒューマンサイエンス振興財団 | Cocktail antibody |
CN105238763A (en) * | 2015-10-26 | 2016-01-13 | 无锡傲锐东源生物科技有限公司 | Anti-PR protein monoclonal antibody hybridomas cell, anti- PR monoclonal antibody generated by same and application |
KR20180113988A (en) | 2015-12-15 | 2018-10-17 | 컨텍스트 바이오파마 인코포레이티드 | Amorphous Ona Pristone Composition and Method of Manufacturing the Same |
US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
CN107200779B (en) * | 2017-07-03 | 2020-04-03 | 中国农业大学 | Preparation method and application of β cell strain for stably over-expressing LAT3 |
CN110215448B (en) * | 2018-03-02 | 2022-09-20 | 中国医学科学院基础医学研究所 | Drug containing transport protein inhibitor, pharmaceutical composition and application |
JP2019158777A (en) * | 2018-03-16 | 2019-09-19 | 東ソー株式会社 | Tumor marker and method for collecting and detecting tumor cell by distinguishing it from contaminant cell |
IT201800004137A1 (en) * | 2018-03-30 | 2019-09-30 | Domenico Marina Di | IN VITRO SCREENING METHOD FOR EARLY DIAGNOSIS OF TUMORS OF THE ORAL CAVITY AND RELATED KIT, BASED IN PARTICULAR ON THE ELISA ASSAY |
CN110376036A (en) * | 2019-07-30 | 2019-10-25 | 河南赛诺特生物技术有限公司 | A kind of preparation method and tumor cell line immunohistochemistry reference substance of tumor cell line immunohistochemistry reference substance |
KR20220141216A (en) | 2021-04-12 | 2022-10-19 | 연세대학교 산학협력단 | A Novel Biomarker for Diagnosing Breast Cancer |
CN116333115B (en) * | 2023-05-12 | 2023-07-28 | 北京纳百生物科技有限公司 | Anti-progesterone monoclonal antibody, kit and application |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000342270A (en) * | 1999-06-04 | 2000-12-12 | Japan Science & Technology Corp | Neutral amino acid transporter having broad substrate selectivity and its gene |
EP1111048A2 (en) * | 1998-09-03 | 2001-06-27 | Japan Science and Technology Corporation | Neutral amino acid transporter and gene thereof |
EP2146208A1 (en) * | 2007-02-06 | 2010-01-20 | J-Pharma Co., Ltd. | Kit for deciding degree of malignancy in prostate cancer and method of using the same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5698410A (en) | 1995-06-07 | 1997-12-16 | Mount Sinai School Of Medicine Of The City University Of New York | Highly sensitive immunocytochemical method for diagnosis of malignant effusions |
JP4592131B2 (en) | 1999-08-05 | 2010-12-01 | ジェイファーマ株式会社 | Transporter using cystine, basic amino acid and neutral amino acid as substrate and its gene |
JP2001228146A (en) | 1999-12-07 | 2001-08-24 | Takeda Chem Ind Ltd | Use of disease-associated gene |
JP2001211886A (en) | 2000-02-07 | 2001-08-07 | Japan Science & Technology Corp | Non-sodium-dependent small neutral amino acid transporter transporting l- and d-amino acids and its gene |
JP3507884B2 (en) | 2000-03-07 | 2004-03-15 | 新潟大学長 | Objective diagnosis of schizophrenia using gene expression as an index |
TWI390034B (en) * | 2006-04-06 | 2013-03-21 | Kyowa Hakko Kirin Co Ltd | Novel anti-CD98 antibody |
GB2460769C (en) * | 2007-11-30 | 2011-09-07 | Applied Genomics Inc | TLE3 as a marker for chemotherapy |
JP2011024537A (en) * | 2009-07-29 | 2011-02-10 | Kinki Univ | Antibody against transporter, and use of the same |
-
2012
- 2012-04-13 KR KR1020137029685A patent/KR101976219B1/en active IP Right Grant
- 2012-04-13 ES ES12770851.9T patent/ES2656988T3/en active Active
- 2012-04-13 EP EP12770851.9A patent/EP2698634B1/en active Active
- 2012-04-13 WO PCT/JP2012/060114 patent/WO2012141285A1/en active Application Filing
- 2012-04-13 JP JP2013509975A patent/JP6075881B2/en active Active
- 2012-04-13 US US14/111,401 patent/US9618512B2/en active Active
- 2012-04-13 CN CN201280023071.2A patent/CN103547923B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1111048A2 (en) * | 1998-09-03 | 2001-06-27 | Japan Science and Technology Corporation | Neutral amino acid transporter and gene thereof |
JP2000342270A (en) * | 1999-06-04 | 2000-12-12 | Japan Science & Technology Corp | Neutral amino acid transporter having broad substrate selectivity and its gene |
EP2146208A1 (en) * | 2007-02-06 | 2010-01-20 | J-Pharma Co., Ltd. | Kit for deciding degree of malignancy in prostate cancer and method of using the same |
Non-Patent Citations (1)
Title |
---|
See also references of WO2012141285A1 * |
Also Published As
Publication number | Publication date |
---|---|
ES2656988T3 (en) | 2018-03-01 |
US20140106377A1 (en) | 2014-04-17 |
CN103547923A (en) | 2014-01-29 |
US9618512B2 (en) | 2017-04-11 |
EP2698634B1 (en) | 2017-11-08 |
KR101976219B1 (en) | 2019-05-07 |
EP2698634A1 (en) | 2014-02-19 |
JPWO2012141285A1 (en) | 2014-07-28 |
WO2012141285A1 (en) | 2012-10-18 |
KR20140019833A (en) | 2014-02-17 |
JP6075881B2 (en) | 2017-02-08 |
CN103547923B (en) | 2015-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2698634A4 (en) | Biomarker for breast cancer | |
HK1193637A1 (en) | Biomarkers for lung cancer | |
EP2718721A4 (en) | Circulating biomarkers for cancer | |
HK1210832A1 (en) | Cancer diagnostics using biomarkers | |
HK1197182A1 (en) | Cancer immunotherapy | |
EP2825674A4 (en) | Thyroid cancer biomarker | |
HUE046152T2 (en) | Individualized vaccines for cancer | |
IL225441A0 (en) | Breast cancer diagnostics | |
ZA201205003B (en) | Methods for treating breast cancer | |
GB2513275B (en) | Biomarkers for Breast Cancer Prediction and Diagnosis | |
PL2931922T3 (en) | Personalized biomarkers for cancer | |
IL237436A0 (en) | Method for screening cancer | |
EP2861766A4 (en) | Methylation biomarkers for breast cancer | |
GB201012590D0 (en) | Methods for diagnosing cancer | |
GB201120860D0 (en) | Cancer immunotherapy | |
EP2686447A4 (en) | Prognostic marker sets for prostate cancer | |
EP2758777A4 (en) | Detecting ovarian cancer | |
EP2894477A4 (en) | Method for determining breast cancer | |
EP2742358A4 (en) | Methods for diagnosing cancer | |
GB2510539B (en) | Biomarkers of cancer | |
EP2753716A4 (en) | Novel risk biomarkers for lung cancer | |
EP2649225A4 (en) | Biomarkers for prediction of breast cancer | |
GB201104556D0 (en) | Biomarkers | |
EP2732287A4 (en) | Methods of diagnosing cancer | |
GB201201466D0 (en) | Breast enhancer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20131115 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20141024 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 16/28 20060101ALI20141020BHEP Ipc: G01N 33/48 20060101ALI20141020BHEP Ipc: G01N 33/53 20060101ALI20141020BHEP Ipc: G01N 33/574 20060101AFI20141020BHEP |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20170523 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP Ref country code: AT Ref legal event code: REF Ref document number: 944627 Country of ref document: AT Kind code of ref document: T Effective date: 20171115 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602012039528 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: FREIGUTPARTNERS IP LAW FIRM DR. ROLF DITTMANN, CH |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2656988 Country of ref document: ES Kind code of ref document: T3 Effective date: 20180301 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20171108 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 944627 Country of ref document: AT Kind code of ref document: T Effective date: 20171108 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180208 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180208 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180308 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20180209 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602012039528 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20180809 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20180430 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180430 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20120413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20171108 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20171108 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20200629 Year of fee payment: 9 Ref country code: CH Payment date: 20200420 Year of fee payment: 9 Ref country code: DE Payment date: 20200420 Year of fee payment: 9 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20200427 Year of fee payment: 9 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 602012039528 Country of ref document: DE |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20210413 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20211103 Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210413 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210430 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210430 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20220701 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210414 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20230426 Year of fee payment: 12 Ref country code: FR Payment date: 20230424 Year of fee payment: 12 |