EP2654904A2

EP2654904A2 - Cyclomethicone-free aerosol formulations

Info

Publication number: EP2654904A2
Application number: EP11805838.7A
Authority: EP
Inventors: Stefan Biel; Sabine Ripke; Heike Miertsch
Original assignee: Beiersdorf AG
Current assignee: Beiersdorf AG
Priority date: 2010-12-21
Filing date: 2011-12-21
Publication date: 2013-10-30
Also published as: BR112013014845B1; BR112013014845A2; WO2012085062A3; WO2012085062A2

Abstract

Cyclomethicone-free aerosol formulations comprising a specific hydrocarbon mixture of oligomers of butene or butadiene with chain lengths of C16 to C32 or more lead to formulations which have a pleasant skinfeel, primarily dry skinfeel, and good settling characteristics of particles present.

Description

Cyclomethicone-free aerosol preparations

The invention encompasses cyclomethicone-free aerosol formulations comprising a specific hydrocarbon mixture of oligomers of butene or butadiene with chain lengths of C16 to C32 and more.

An aerosol is a disperse system in which a solid or liquid is extremely finely dispersed in a gas. The aerosol is usually only when using a suitable spray system by spraying solutions, emulsions or suspensions self-produced, including, for example, spray cans can be used, in which a liquefied compressed gas serves as a propellant gas. When the pressure valve is opened, the mixture of propellant and active substance solution escapes through a fine nozzle which evaporates the propellant and leaves the finely distributed spray material as an aerosol. in the

In terms of application technology, the term aerosol is frequently used by the skilled person also in the sense of aerosol sprays, i. Here, "aerosol" is understood not to be the pure spray, but a compressed gas packaging together with dispensing or metering device and contents.

The contents include active ingredient solution and propellant. The active substance solution is the sum of all the constituents of preparation without the propellant. The term "active substance solution" is also used when the preparation is e.g. in the form of a suspension or emulsion.

As Sprühgut, spray, spray or spray cone synonymous with the one-time actuation of the aerosol device expelled filling material is considered.

Usually, antiperspirants (AT) and deodorants (Deo) are offered in a variety of product forms, with scooters, pump sprayers and aerosols dominating in Europe, and pens in the US, Central and South America. Both anhydrous (suspensions) and water-containing products (hydro-alcoholic formulations, emulsions) are known.

Antiperspirants or deodorants are used to eliminate or prevent body odor, which arises when the in itself odorless fresh sweat through

Microorganisms is decomposed. The usual cosmetic deodorants are based on different active principles.

In common usage there is not always a clear distinction between the terms "deodorant" and "antiperspirant". Rather, especially in the

German-speaking countries - products for use in the armpit area as a whole This is done irrespective of the question as to whether an antiperspirant effect is also present.

In the prior art are found almost exclusively in anhydrous suspensions

Deodorant or antiperspirant formulations, the silicone oils, in particular

Cyclomethicones.

Volatile silicone oils, in particular cyclomethicones, serve as a carrier oil for the active ingredients and thus enable a uniform application to the skin. Due to the high volatility Cyclomethicone evaporates very quickly from the skin, without causing a sticky feeling. By evaporation of the silicone oil, white residues are very quickly visible through the AT agent or the thickener on the skin (whitening effect). Formulas with cyclomethicones are perceived by many consumers to be too dry and not very caring.

Cyclomethicones, e.g. INCI name for an octamethylcyclotetrasiloxane having the general formula where I = 3 - 6

Offered are, for example, cyclomethicone / decacyclopentasiloxane (D5) or

Cyclomethicone / dodecamethylcyclohexasiloxane (D6). The mixtures can be used on their own or in corresponding preparations as volatile silicone compounds (Cosmet. Toiletries 107, No. 5, 27 [1992]).

Disadvantages of the cyclopentasiloxanes (D5) and the volatile silicone oils in general are:

a) Availability

Due to high consumption of silicone oils in photovoltaics and in the building materials industry, a permanent supply of silicone oils for cosmetics is not unhindered.

b) Sustainability

Silicone oils are often characterized by a lack of degradability.

c) white effect

Silicone oil-containing formulations show the disadvantage of the whiteness of antiperspirants, especially black cotton clothing. Silicone oil-free formulations with the same concentration of the antiperspirant active ingredient in the form of a powder show a significantly lower white content.

d) Nursing feeling

Silicone oils in cosmetics provide the consumer with a low care feeling. Volatile silicone oils also have significant weaknesses in their compatibility with cosmetic agents. Due to their strong hydrophobic character

Silicone oils in particular impurities with a polar character hardly to solve. Furthermore, silicone oils are virtually unable to support the penetration of cosmetic ingredients into the skin.

WO 2005063188 A1 describes silicone-free AT sprays.

DE 102009027604 A1 discloses alkane mixtures containing preferably at least 70% by weight, preferably at least 85% by weight, in particular at least 95% by weight, of alkanes having an even number of carbon atoms. A special version is a

Isoalkangemic, consisting essentially of alkanes with 8 or 12 or 16

Carbon atoms.

DE 102009027604 A1 discloses natural and synthetic hydrocarbons, such as, for example, paraffin oils, C18-C30 isoparaffins, in particular isoeicosane, polyisobutenes or polydecenes, for example under the name Emery® 3004, 3006, 3010 or under the name Ethylflo® by Albemarle or Nexbase® 2004G available from Nestle, as well as 1,3-di- (2-ethylhexyl) -cyclohexane (available, for example, under the trade name Cetiol®S from Cognis). These hydrocarbons are nonvolatile non-silicone oils.

DE 69625368 discloses isohexadecane as an exchange to cyclomethicones (D5). In addition to the volatile silicones, a volatile hydrocarbon may be included in the composition, either alone or together with another non-aqueous carrier. The volatile hydrocarbon, z. B. a hydrocarbon with 10 to 26

Carbon atoms, has sufficient volatility to avoid leaving a sticky feeling on the skin.

WO 2000030598 A1 discloses the replacement of volatile silicone oils with volatile ones

Hydrocarbons. Since these skin incompatibilities even at low

Concentrations can cause the preparation of WO 2000030598 A1 a so-called "mitigating material" is added, preferably non-volatile silicone oils, wherein in non-silicone oils petrolatum is preferably added as a "mitigating material". The volatile hydrocarbons are characterized by

o a solubility parameter <7.5

o a vapor pressure of preferably 0.01 to 6.0 mmHg

o a boiling point of <250 ° C It is desirable to provide aerosol formulations that, despite the lack of otherwise commonly used cyclomethicones

• a pleasant feeling on the skin, especially a dry skin feeling

• good skin compatibility

• good distribution / spreading on the skin

• good effectiveness

• good settling behavior of contained particles

• good perfume release, even over a longer period of time, without one

To leave unpleasant, like greasy or greasy feeling on the skin

• little residue on and in clothing and / or

• good suitability for shaved armpits / underarm shaving

demonstrate.

The invention is a cyclomethicone-free aerosol preparation comprising

Hydrocarbon mixture with a carbon number Cx with x = 16 + 4 * a, where a is chosen from the set of natural numbers N = {0, 1, 2, 3, ....}. The proportion of

Hydrocarbons having a = 0 is at least 50 wt.%, Preferably at least 55 wt.%, In particular at least 60 wt.%, Based on the total mass of

Hydrocarbon mixture.

The hydrocarbon mixture is formed from oligomers of butene or butadiene.

The proportion of the hydrocarbon mixture according to the invention based on the

Total preparation (i.e., including propellant gas) is advantageously 0.05 to 65 wt.%, Preferably 0, 1 to 40 wt.%, Particularly preferably 0.2 to 32 wt.%, Based on the total mass of the preparation.

The use of this oil mixture showed surprisingly a change in the Theological properties of the preparation contained. The viscosity of an AT preparation, a particle suspension is increased due to the hydrocarbons, which has a positive effect on the decay behavior of the AT agent particles in the aerosol after shaking. For this reason, in the active solution, the content of phyllosilicates can be reduced, which has a positive effect on the sensors of the systems by reducing the dull skin feeling and results in a reduction of the white residues on skin and clothing, since the phyllosilicates, in contrast to AT -Mittel are not soluble in water and remain permanently on skin and clothing. According to the invention, the proportion of hydrocarbons Cx with a> 1 is at least 0.5% by weight and with a> 4 (ie HC> C28) less than 0.5% by weight, in each case based on the total mass of the hydrocarbon mixture.

That at least more than 0.5% by weight of C20, C24, C28 or C30

Contain hydrocarbons. The proportion of C32, C36 etc. is less than 0.5 wt.%.

The proportion of constituents in the hydrocarbon mixture with chain lengths equal to C16 is at least 50%, preferably at least 55%, and hydrocarbon mixtures consisting exclusively of constituents with C16 as chain lengths are not

according to the invention.

A preferred hydrocarbon mixture Cx comprises 66% C16, 31% C20 and

3% hydrocarbons with chain length> C24.

The hydrocarbons with Cx, x> 20, are considered as non-volatile at room temperature hydrocarbons. That The hydrocarbon mixture according to the invention comprises at least 50% by weight of volatile hydrocarbons (C16) and more than 0.5% by weight of non-volatile hydrocarbons (C20, C24, C28 etc.).

This mixture of volatile and non-volatile hydrocarbons Cx, the oligomers of butene and butadiene, surprisingly leads to the advantages

• a pleasant feeling on the skin, especially a dry skin feeling

• good skin compatibility

• good distribution / spreading on the skin

• good effectiveness

• good settling behavior of contained particles

• good perfume release, even over a longer period of time, without one

To leave unpleasant, like greasy or greasy feeling on the skin

• little residue on and in clothing and / or

• good suitability for shaved armpits / underarm shaving

Achieving these benefits from hydrocarbon blends was unpredictable, which also opened up a favorable cyclomethicone alternative.

Hydrocarbon mixtures are also known as polyisobutenes, isoparafines,

Isohexadecangemisch called. By contrast, however, the hydrocarbon mixtures according to the invention are characterized by a specific ratio of C16 to Cx, with x> 16. The hydrocarbon mixture Cx according to the invention therefore differs from pure hydrocarbons having a chain length C16 (isohexdacenes) and thus also from the hydrocarbons disclosed in the prior art, such as, for example, WO 2000030598 A2.

The hydrocarbons used in WO 2000030598 A2 have a boiling point <250 ° C, whereas the hydrocarbon mixtures Cx according to the invention have a boiling range of 253-348 ° C.

The hydrocarbon mixtures according to the invention are branched and linear C4 segments, oligomers of butene or butadiene.

The formulations further comprise advantageously a mixture of at atmospheric pressure gaseous and liquid monomers and oligomers of butane (C4) _y with y = 4 * b, where b from the set of natural numbers N ₀ = {1, 2, 3,. ...} is selected.

The cyclomethicone-free aerosol preparations according to the invention are preferably anhydrous, in particular anhydrous, cosmetic or dermatological preparations, in particular antiperspirant preparations.

Anhydrous means that the proportion of water in the aerosol preparations, apart from possibly with entrained impurities or water of crystallization, is almost 0% by weight.

The cyclomethicone-free aerosol formulations comprising the specific

Hydrocarbon mixtures of oligomers of butene or butadiene with chain lengths of C16 to C32 and more lead to formulations which have a pleasant skin feel, especially a dry skin feel, and a good sedimentation of contained particles.

As further advantageous has been found that the preparations comprise one or more lipids selected from the group of isopropyl esters, alkyl benzoates, nonvolatile silicone oils and / or triglycerides, in particular isopropyl palmitate, C12-15 alkyl benzoate, Dimethicone and Caprylic / Capric triglyceride.

Particularly preferred are the lipid combinations of isopropyl palmitate and C12-15 alkyl benzoate and / or dimethicone and caprylic / capric triglyceride.

Surprisingly, in addition to the advantages of the hydrocarbon mixture according to the invention, this oil combination has a cyclomethicone-like effect Skin sensation as shown in Figure 1. This is despite the fact that the lipids as individual components certainly give a more oily skin feel than cyclomethicones themselves. The combination of the oils can increase the masking properties. In addition, the formulation is attributed to a higher underarm odor reduction.

Lipids are fats, fatty substances and oils. For cosmetics, they are of importance, above all, as emollient ingredients and as skin-specific lipids of the horny layer, which are stored between the horny cells. They enable the skin to store moisture. In addition to the nourishing aspect, lipids become the cosmetic

Preparations added to ensure better distribution on the skin and to improve the sensory properties of the preparations.

Through the use of these lipids, on the one hand, an additional nourishing skin sensation is mediated and, in addition, the white residues of the aluminum chlorohydrate are masked. This means that less white residue is visible on the skin and black clothing.

As previously indicated, in the prior art highly volatile silicone oils, such as

Cyclomethicone used as the main component in aerosol sprays. Through the use of the abovementioned hydrocarbons according to the invention and optionally the lipids which are preferably to be selected, the proportion of cyclomethicones can be significantly reduced or

Cyclomethicone can be completely replaced.

In principle, volatile cyclic silicone oils are advantageously dispensed with.

Antiperspirant (AT) sprays in which cyclomethicones have been partially or completely replaced by one or a mixture of the hydrocarbons and lipids of the invention were as well as the reference product by consumers

Cyclomethicone assessed, as the following studies show.

Figure 1 shows the result of an in-use test with 54 subjects who semimonadically only one week, the new development of the anhydrous antiperspirant with a hydrocarbon mixture Cx and triglyceride (Example 22) and then two weeks as reference the comparison product with the silicone oil cyclomethicone (Example 23 ) have tested. In conclusion, the above points were answered in a questionnaire by the

Subjects answered (white bars: comparative product with cyclomethicone, dark bars: new development with hydrocarbon mixture and triglyceride).

Hydrocarbons generally have the disadvantage that they are a very bad

Have packaging compatibility. Already after a short storage time they migrate Hydrocarbons in the packaging and can thus limit the function of the packaging. In the aerosols, an incompatibility of the oils with the plastic parts of the valve and the spray head is conceivable.

The inventively preferred hydrocarbons Cx with a proportion of at least 50% of hydrocarbons having a chain length equal to C16 now show the advantages of the raw material group of hydrocarbons, such as. Stability in market formulas

Exchange of Cyclomethicone, a comparable sensor as with Cyclomethicone, while they do not have the typical disadvantage of packaging incompatibility or only after storage for a very long period of time (eg 1 year) at a temperature well above + 25 ° C (eg + 35 ° C , + 40 ° C, + 45 ° C). The main difference lies in the kinetics with which the hydrocarbon migrates into the packaging. The kinetics are significantly slowed down so that the consumer can store the product for years at + 25 ° C, without it comes to the typical for hydrocarbon packaging deformations.

In order to investigate the packaging compatibility of the preparations according to the invention, tests were carried out.

For this purpose, the valve / the spray head of an aerosol can in a glass vessel in the

appropriate oil immersed. The jar is closed with a screw cap and stored for 6 days at + 45 ° C.

Subsequently, the valves / spray heads are examined for changes. The treated valves / spray heads are then tested for their functionality. It turns out that the packaging compatibility of the formulations of the invention is very good, the kinetics of the migration of the oil into the packaging material is significantly slower than with other hydrocarbons such as isohexadecanes or isododecanes and the polypropylene spray head still sits firmly on the can.

A mixture of hydrocarbons with a share of at least 50% of chain lengths equal to C16 has been found to be particularly positive. While

Hydrocarbon blends having predominantly shorter chain moieties (e.g., C13-16 isoparaffin) and hydrocarbon blends containing almost no chain length greater than C16, such as isododecanes and isohexadecanes, exhibit inferior packaging agent compatibility, and this particular blend of the present invention has exceptionally good packaging compatibility.

In the context of a cyclomethicone exchange, the lipids according to the invention represent a particularly cost-effective alternative. Since these raw material mixtures are free of silicones are still the basis for a shortage of silicone oils

Antiperspirant formulations available.

Due to the advantage shown in the exchange of cyclomethicones by

Hydrocarbon mixtures according to the invention, it is therefore advantageous the content of cyclomethicones in the preparation 0 wt.%, Based on the total mass of

Preparation including propellant, to choose. As Cyclomethicone are in particular

Cyclopenta-siloxanes (D5), cyclohexasiloxanes (D6) or mixtures thereof.

The combination of one or more lipids selected from the group of isopropyl esters, preferably isopropyl palmitates, alkyl benzoates, preferably C12-15 alkyl benzoates, nonvolatile silicone oils, preferably dimethicones, triglycerides, preferably

Caprylic / capric triglycerides, with hydrocarbon mixtures Cx in aerosol formulations is extremely advantageous.

For the expert unexpected, showed in the inventive

Aerosol preparations also a better settling behavior of the particulate agent in the aerosol with very good packaging compatibility. The particles sediment much slower when cyclomethicones (D5) against the invention

Hydrocarbon mixture has been replaced.

Antiperspirants (AT) are antiperspirants that - in contrast to the

Deodorants, which generally prevent microbial decomposition of already formed sweat - to prevent the secretion of sweat at all.

The desired minimization of sweat secretion can be realized by various mechanisms. This traditionally includes the use of astringents, which

Protein precipitation and coagulation cause and thus cause a constriction or closure of the sweat gland.

Novel AT-Wrkers are based, for example, on the principle of anticholinergics, which interrupt the nerve stimuli that lead to increased secretion of the sweat glands.

Another principle of novel AT-Wrker is based on the influence of

Membrane transport processes in the cell. Thus, specific aquaporin inhibitors inhibit the proteins that form channels in the cell membrane to facilitate the passage of water and other molecules. Ion channel inhibitors also have an effect on membrane transport or osmosis processes. Another novel AT-turning mechanism can be realized by the use of short-chain, vicinal diols, possibly due to their osmotic activity. Thus, by applying an agent no influence on the sweat secretion is exercised, so no antiperspirant effect is realized, according to the invention no antiperspirant.

Accordingly, antiperspirant active substances according to the invention include those substances which have an influence on perspiration secretion.

In contrast to the antiperspirants pure deodorants cause no active

Influencing the sweat secretion, but only the control or influence of the body or underarm odor (odor control agent). common

Wrkmechanismen this are antibacterial effects, as they also show the non-colloidal silver, odor neutralization (masking), influencing bacterial metabolism, the pure perfuming as well as the use of precursors certain

Perfume components, which are converted by enzymatic conversion to fragrant substances.

Preparations may in addition to the actual antiperspirant Wrkstoffen (AT-Wrker) also contain substances that inhibit the microbial degradation of sweat, such as. B. butyloctanoic acid. However, butyl octanoic acid shows only a deodorizing effect and no antiperspirant action, since no influence on the sweat secretion can be deduced from the influence on the bacterial skin flora.

In particular, in the case of antiperspirants based on aluminum salts, it may be possible to dispense with the further addition of substances having a purely deodorizing action, since these have per se an antimicrobial potential. Furthermore, the reduced supply of water due to the reduced sweat secretion also inhibits bacterial growth.

Antiperspirant active ingredients in the context of the present application are in particular to be selected from the following groups.

As antiperspirant active ingredients are used in particular astringents, especially aluminum compounds. The previously used, strongly acidic salts

Aluminum sulfate or chloride and the agaric acid are largely by

Aluminum hydroxychloride and alcoholates have been replaced. The following list of advantageous antiperspirant active agents should not be restrictive in any way: aluminum salts:

• aluminum salts such as aluminum chloride AICI3, aluminum sulfate AI2 (S04) 3

• Aluminum chlorides of the empirical empirical formula [AI2 (OH) mCln], where m + n = 6

• Aluminum chlorohydrate [Al2 (OH) 5Cl] x H20

^■ standard AI complexes: Locron P (Clariant), Micro-Dry 323 (Summit Reheis),

Aloxicoll PF 40 (BK Giulini). o Activated AI Complexes: Reach 103 (Summit Reheis), AACH-7171 / AACH-7172 (Summit Reheis), Aloxicoll P (BK Giulini), Aloxicoll SD100 (BK Giulini)

• Aluminum sesquichlorohydrate [Al2 (OH) 4,5CI1,5] x H20

Standard AI complexes: Aloxicoll 31 P (BK Giulini)

, Aluminum dichlorohydrate [Al 2 (OH) 4Cl 2] x H 2 O

The aluminum salts may be in ground form or as hollow spheres or as

Mixture of these present. The density of these particles is advantageously in the range of 0.7 to 2.0 g / cm ³ .

Therefore, aerosol preparations according to the invention may also comprise particulate active substances, in particular aluminum chlorohydrates, having a particle density in the range from 0.7 to 2.0 g / cm ³ , since they improve spray cone formation.

In particular, antiperspirants and their suspending aids are to be selected as particulate active substances.

Suspension aids increase the stability of particles in suspensions. In anhydrous antiperspirant formulations are preferably modified phyllosilicates,

Clay minerals and / or silicas used, z. B. hectorites, bentonites and / or silica.

Also advantageous may be the use of AT salt suspensions or gels in which aluminum salts present in powder form are dispersed in various oils.

Likewise, an antimicrobial silver citrate complex, as described in DE 202008014407, preferably be used as a cosmetically active ingredient in the cosmetic preparations.

The antiperspirant active ingredients from the above-described groups are preferably used in the formulations according to the invention in an amount of 0.5 to 10% by weight, preferably 2 to 6% by weight, based on the total mass of the preparation, i. including the possibly existing propellants used.

When using about 35 wt.% AACH (activated aluminum chlorohydrate) in the

Active ingredient solution for an aerosol spray (without propellant gas) and a filling ratio of about 15:85 (solution to propellant gas) is a proportion of about 5.25 wt.% AACH im

End product be present. Aluminum chlorohydrates, in particular activated aluminum chlorohydrates (AACH), are preferably used as antitumor agents in antiperspirant aerosol preparations.

In AT aerosols, the active ingredients should be easy to agitate and during the

Do not sediment the application too quickly.

AT agents from the group of anticholinergics, such as, for example, 4 - [(2-cyclopentyl-2-hydroxyphenylacetyl) oxy] -1, 1-dimethylpiperidinium salts, especially 4 - [(2-cyclopentyl-2-hydroxyphenylacetyl) oxy] 1, 1-dimethyl-piperidinium bromide can to a proportion of preferably 0.05 to 1, 0 wt.%, Preferably 0, 1% -0.7%, in particular 0.3% -0.5 wt.%, Based be added to the total mass of the preparation with propellant gas. Of course, it is possible to add further or other antiperspirant active ingredients and / or deodorants as a cosmetically active ingredient.

Preferably, one or more compounds from the group of deodorants, in particular perfumes, alcohols, antimicrobial and / or antiperspirant active ingredients are selected as the cosmetically active ingredient.

The aerosol preparations according to the invention preferably comprise one or more lipids, in particular previously mentioned hydrocarbon lipids selected from the group

Isopropyl esters, alkyl benzoates, nonvolatile silicone oils, triglycerides and

Hydrocarbon mixtures Cx and particulate active substances, in particular

Aluminum chlorohydrate, having a particle density in the range of 0.7 to 2.0 g / cm ³ .

In the aerosol according to the invention is preferably at least one hydrocarbon with C4, z. As n-butane or iso-butane used. In addition, further hydrocarbons such as propane, propene, isobutene, n-pentane, n-pentene, iso-pentane, iso-pentene may be included.

Also hydrophilic propellants, such. As carbon dioxide, can be used advantageously in the context of the present invention, when the proportion of hydrophilic gases is selected low and lipophilic propellant gas (eg., Propane / butane) is present in excess.

Propane, butane, isobutane or mixtures of these propellant gases are particularly preferred. For the purposes of the present invention, the gases mentioned can be used individually or in any desired mixtures with one another. Preference is given to using mixtures having pressure stages of from 1.0 to 3.5 bar. Preferably from 2.5 to 3.0, most preferably a pressure of 2.7 bar. Preferred filling ratios of solution to propellant gas are 80:20 to 5:95, preferably 50:50 to 10:90. The aerosol preparations, in particular deodorant or antiperspirant preparations, according to the invention may contain cosmetic adjuvants and other active ingredients such as are commonly used in deodorant or antiperspirant preparations, such as. Preservatives, preservatives, bactericides, perfumes, anti-foaming agents, dyes and color pigments, thickeners, moisturizing and / or moisturizing substances, fats, oils, waxes or other common ingredients of a cosmetic or dermatological formulation such as alcohols, polyols, polymers, Foam stabilizers, electrolytes, organic solvents or silicone derivatives if the additive does not impair the required properties or according to the invention

is excluded.

Preferred application form for the formulations according to the invention are anhydrous aerosols which come in aluminum cans on the market. This is preferred

Application form, as it is the most common form of Deo / AT in the world. Also due to the very good packaging compatibility is an application in anhydrous

Formulations recommended because even after storage at + 40 ° C over a period of 6 months hardly changes in packaging.

The following examples illustrate preparations according to the invention. The data are by weight, based on the total mass of the respective preparations.

1 example 2 examples 3 examples 4 examples 5 examples 6 examples 7

Aluminum Chlorohydrate 5,250 5,250 2,505 2,505 2,505 6,000 2,505

Hydrocarbon mixture 5,850 5,730 6,825 6,825 6,825 4,500 5,055 Cx with 100%> C16

Dimethicone (100 cSt) 1, 500 1, 500 1, 710 1, 710 1, 710 2,250 3,000

Caprylic / Capric Triglycerides 0,000 0,000 1, 710 1, 710 1, 710 3,000

Dimethicone + Dimethicone 0.810 0.810 0.810 0.810 0.000 (Gum Blend)

Dimethicone + Dimethicone 0.810

(Gum Blend)

C13-16 isoparaffin + 0.810

Dimethicone + C10-13

Isoparaffin (Gum Blend)

Perfume 0.990 0.990 0.990 0.990 0.990 0.990 0.990

Disteardimonium hectorite 0.600 0.600 0.375 0.375 0.375 0.375 0.375

Propylene Carbonates 0, 120 0.075 0.075 0.075 0.075 0.075

Butane 51, 000 51, 000 51, 000 51, 000 51, 000 51, 000 51, 000 Isobutane 17,000 17,000 17,000 17,000 17,000 17,000 17,000

Propane 17,000 17,000 17,000 17,000 17,000 17,000 17,000

Aluminum Chlorohydrate 6,000 6,000

Hydrocarbon mixture 3,378

Cx with 100%> C16

Dimethicone (100 cSt) 1, 689 0.450

Caprylic / Capric Triglycerides 1, 689

Cyclomethicone

Silicone Gum Blend 0.804 0.804

Perfume 0.990 0.990

Disteardimonium hectorite 0.375 0.600

Propylene carbonate 0.075

Butane 51, 000 51, 000

Isobutane 17,000 17,000

Propane 17,000 17,000

In the list below are the raw materials used and their

Named trade names,

INCI trade name manufacturer / supplier

Aluminum Chlorohydrate Activated Aloxicoll P BK Giulini Chemistry

Dimethicone + Dimethicone DC 1413 Fluid Dow Corning

Dimethicone + Dimethiconol DC 1503 Fluid Dow Corning

C13-16 isoparaffin + DC BY 25-320 Dow Corning

Dimethicone + C10-13

isoparaffin

Dimethicone 100 cSt BRB Silicones Oil DM 100 BRB International

Caprylic / Capric Triglycerides Myritol 312 BASF

Cyclomethicone Baysilone SF 1202 Momentive Performance

Materials Inc

Propylene Carbonates 807051 Propylene carbonate Merck

for synthesis

Disteardimonium Hectorite Bentone 38V CG Elementis

Butane + Isobutane + Drivosol 27 D60 Evonik Oxeno

Propane

Claims

claims

1. Cyclomethicone-free aerosol formulations comprising a hydrocarbon mixture having a carbon number Cx with x = 16 + 4 * a, where a is selected from the set of natural numbers N = {0, 1, 2, 3, ....}, The Fraction of hydrocarbons with a = 0 at least 50% by weight, a> 1 at least 0.5% by weight and a> 4 less than 0.5% by weight, in each case based on the total mass of the hydrocarbon mixture.

2. Preparation according to claim 1, characterized in that the proportion of

Hydrocarbons having a = 0 at least 55 wt.% Is, based on the

Total mass of the hydrocarbon mixture.

3. Preparation according to one of the preceding claims, characterized in that the preparation comprises a mixture of gaseous at normal pressure and liquid mono- and oligomers of butane (C4) _y with y = 4 * b, where b from the set of natural numbers N ₀ = {1, 2, 3, ....} Is selected.

4. Cosmetic or dermatological preparation according to one of the preceding claims.

5. Preparation according to one of the preceding claims, characterized in that the preparation is anhydrous.

6. Preparation according to claim 4 or 5, characterized in that the preparation comprises one or more lipids selected from the group of isopropyl esters, alkyl benzoates, non-volatile silicone oils and / or triglycerides.

7. A preparation according to claim 6, characterized in that the lipids are selected from the group isopropyl palmitate, C12-15 alkyl benzoate, dimethicone and / or

Caprylic / capric triglyceride.

8. Preparation according to claim 6 or 7, characterized in that as lipids the

Combinations of isopropyl palmitate and C12-15 alkyl benzoate or caprylic / capric triglyceride and dimethicone.

9. Preparation according to one of the preceding claims 4 to 8, characterized in that the preparation comprises one or more particulate active ingredients having a particle density in the range of 0.7 to 2.0 g / cm ³ .

10. Preparation according to one of the preceding claims 4 to 9 comprising one or more antiperspirant and / or deodorant active ingredient.

1 1. A preparation according to any one of the preceding claims 9 or 10 characterized

characterized in that selected as particulate active ingredients Aluminiumchlorohydrate.

12. A preparation according to claim 11, characterized in that as particulate active ingredients activated aluminum chlorohydrate (AACH) are selected

13. A preparation according to claim 9, characterized in that as particulate substances

Suspending aids are included.