EP2512283A2 - Process and system for iontophoretic wrinkle reduction - Google Patents
Process and system for iontophoretic wrinkle reductionInfo
- Publication number
- EP2512283A2 EP2512283A2 EP10838291A EP10838291A EP2512283A2 EP 2512283 A2 EP2512283 A2 EP 2512283A2 EP 10838291 A EP10838291 A EP 10838291A EP 10838291 A EP10838291 A EP 10838291A EP 2512283 A2 EP2512283 A2 EP 2512283A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- patch
- current
- wrinkle
- fine line
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D44/00—Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
- A45D44/22—Face shaping devices, e.g. chin straps; Wrinkle removers, e.g. stretching the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/22—Electromedical belts, e.g. neck chains, armbands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/328—Applying electric currents by contact electrodes alternating or intermittent currents for improving the appearance of the skin, e.g. facial toning or wrinkle treatment
Definitions
- the present invention relates and is directed to a process or method of use and a system including a disposable patch to treat wrinkles and fine lines with a chemical composition administered by iontophoresis.
- moisturizers containing amino acids play a significant role in skin care by increasing skin elasticity and smoothing the skin.
- anti-aging active agents are known to change the skin condition by smoothing and tightening.
- Chemical compositions may be administered topically, such as lotions, or administered through transdermal patches. Additionally, chemical compositions may be administered by direct injection. Chemical compositions presently available include those which moisturize the outer skin or epidermis. Other compositions tend to promote cell growth in the skin. Other treatments of wrinkles and fine lines include botulinum toxin (marketed under the trademark Botox®) which inhibits neurotransmission in nerve cells, thereby causing contracted muscles to relax. In order to increase the speed and effectiveness of delivery of chemical compositions for treatment, it is known to utilize sonic vibrations. For example, Fahim (U.S. Patent No. 4,372,296) discloses topical treatment of acne with zinc salt and ascorbic acid in a pharmaceutical carrier which is applied with ultra sonic vibrations.
- Stephen et al. (U.S. Patent No. 4,979,938) disclose a method of treating acne using an applicator electrode having a solution capable of producing hydroxyl ions.
- An applicator electrode is placed against the skin and a voltage differential is applied to produce and drive hydroxyl ions into the skin tissue.
- Sun et al. U.S. Patent No. 7,479,133 discloses a device for treating acne or rosacea by applying an electrical charge with two conductive electrodes in communication with a carrier containing an electrolyte.
- Durand patent publications U.S. Patent Publication No. 2009/0048556 and 2009/0149800 disclose a drug delivery system including a pair of electrodes coupled to drug reservoirs 24 controlled by a microprocessor 12.
- the microprocessor may be programmed through a wireless signal receiver.
- the present invention is directed to a process or method of use and a system for wrinkle reduction.
- the system includes a patch assembly applied and adhesively secured to the skin of the consumer.
- Each patch assembly includes a substantially planar top sheet and a substantially planar substrate. Connectors or snaps pass through the top sheet and substrate. On the substrate is a layer of a chemical composition including active ingredients and an adhesive in order to adhere to the skin.
- the patch assembly or assemblies are connectable to a detachable electronic locket assembly.
- the locket assembly may include a housing to form an enclosure. Within the enclosure of the housing is a battery which powers a microprocessor based controller or printed circuit board (PCB).
- the controller is wired to a pair of electrodes through wires to a wiring harness.
- the housing, the battery and the controller are suspended from the wiring harness.
- the patch assembly or assemblies are positioned and aligned on the skin so that the chemical composition is in contact with and applied to the skin.
- a pair of electrodes are connected to the connectors or snaps of the patch assembly.
- a current is applied from the locket assembly through the electrodes into the chemical composition of the patch assembly for a selected time period.
- the active ingredients of the chemical composition are propelled into the skin of the consumer in order to relax the skin.
- the current is stopped and the patch assembly is removed.
- the patch assembly may then be disconnected from the locket assembly.
- the patch assembly may thereafter by discarded and the locket assembly may be reused.
- Figure 1 is an illustration of a first preferred embodiment of a process and system for iontophoretic wrinkle reduction in accordance with the present invention
- Figure 2A illustrates a prospective view and Figure 2B is an exploded view of patch assemblies of the first preferred embodiment of the present invention
- Figure 3A is a patch assembly of a second preferred embodiment while Figure 3B is an exploded view of the patch assembly shown in Figure 3 A;
- Figure 4 illustrates an exploded view of an electronic locket assembly utilized in connection with the present invention
- FIGS 5A, 5B and 5C show alternate views of the lock assembly shown in Figure 4;
- Figure 5D is a sectional view taken through section line D-D of Figure 5 A;
- Figure 6 is a diagrammatic flow chart of the process or method of application of the present invention.
- Figure 7 illustrates a schematic representation of delivery of the electric current cycle during usage of the present invention.
- the present invention includes at least two preferred embodiments - a first preferred embodiment utilized on the skin surrounding the eyes of a consumer and a second preferred embodiment utilized on the forehead and bridge of the nose of a consumer.
- Figure 1 is an illustration of the first preferred embodiment 10 of the present invention surrounding the eyes of a consumer.
- a pair of patch assemblies 12 and 14 are applied and adhesively secured to the skin of a consumer surrounding the eyes.
- Figure 2 A illustrates a perspective view of the patch assemblies 12 and 14 prior to use and Figure 2B is an exploded view of the patch assemblies 12 and 14 illustrating the components thereof.
- Each of the patch assemblies 12 and 14 may include a substantially planar top sheet 16 and 18, respectively.
- the patch assemblies 12 and 14 may also include a substantially planar substrate 20 and 22, respectively.
- the top sheet 16 and 18 and the substrates 20 and 22 each have holes or apertures which are aligned in order to receive conductive connectors or snaps 24 and 26 that pass therethrough.
- Each of the connectors or snaps may be in two-part form. In one non-limiting example, known type electro-mechanical connectors may be utilized.
- Adjacent and on the substrates 20 and 22 are layers of a chemical composition, which may be in the nature of a hydrogel 28 and 30, respectively.
- the hydrogel 28 and 30 will contain active ingredients of the chemical composition and may also include an adhesive in order to adhere to the skin.
- the active ingredients may include hyaluronic acid, stressed yeast cell lysate, yeast cell derivative, and cross-linked synthetically derived protein.
- the hyaluronic acid may be in the range of .1 to 15%.
- the hydrogel 28 and 30 are in fluid communication with the connections or snaps 24 and 26. Accordingly, current or voltage delivered to the connectors or snaps is delivered to the hydrogel. Alternatively or additionally, carbon ink may be added to the substrate layers to improve the conductivity of the electrode assembly.
- the patch assemblies 12 and 14 may be stored and transported on a release liner sheet
- the patch assemblies may be easily peeled off or removed from the liner sheet.
- the entire assemblies and the liner sheet 32 may be stored in a pouch 34.
- a second preferred embodiment of the present invention to be applied to the forehead and bridge of the nose is shown in assembled form in Figure 3A and is shown exploded in Figure 3B.
- the second preferred embodiment includes a patch assembly 42 shown fully assembled in Figure 3A prior to use.
- the patch assembly 42 may include a substantially planar top sheet 44 and an aligned substantially planar substrate 46.
- the top sheet 44 and substrate 46 each include aligned holes or apertures to receive a pair of connectors or snaps 48 and 50.
- the patch assembly includes a layer of chemical composition in the hydrogel 52.
- the entire patch assembly 42 may be transported and stored on a liner sheet 54.
- the patch assembly 42 and the liner sheet may be stored in a pouch 56.
- the patch assemblies are disposable after use.
- the patch assemblies are connectable to an electronic locket assembly 60.
- FIG 4 illustrates an exploded view of the electronic locket assembly 60.
- Figures 5A, 5B and 5C show alternate views of the locket assembly 60 with Figure 5D illustrating a sectional view taken through section line D-D of Figure 5 A.
- the locket assembly 60 may include a front housing 62 which mates with a rear housing 64 to form an enclosure. Attached to the housing may be an optional clasp or clip 66.
- a battery 68 Within the enclosure of the housing is a battery 68 which powers a microprocessor based controller or printed circuit board (PCB) 70.
- a contact or contacts 72 connect the battery 68 to the controller 70.
- PCB printed circuit board
- the microprocessor based controller 70 is, in turn, wired to a pair of electrodes 74 and 76 through wires or a wiring harness 78.
- the housing 62 and 64, the battery 68 and controller 70 may hang from or be suspended from the wiring harness 78.
- the process and system of the present invention uses iontophoresis as the motive force for transdermal delivery of a defined amount of active ingredients.
- the patch assembly or assemblies are removed from the storage pouch and removed from the liner sheet and then positioned and aligned on the skin so that the chemical composition is in contact with and applied to the skin.
- the adhesive in the chemical composition serves to removably secure the patch assembly to the skin.
- the pair of electrodes 74 and 76 are connected to the connectors or snaps of the patch assembly either in advance of application to the skin or after application. The process is continued by electronically activating the patch assembly.
- a current is applied from the locket assembly 60 through the electrodes 74 and 76 into the chemical composition of the patch assembly for a selected time period.
- the active ingredients of the chemical composition are propelled into the skin of the consumer in order to relax the skin or achieve other beneficial results.
- the current is stopped and the patch assembly is removed from the skin.
- the patch assembly may be disconnected from the locket assembly 60.
- the patch assembly may thereafter be discarded.
- any residue of the chemical composition may be massaged into the skin.
- the procedure may be periodically repeated.
- Figure 6 illustrates a diagrammatic flow chart of the process or method of application of the current during the delivery cycle of the invention.
- the microprocessor based controller 70 will conduct a self initialization test as shown in Box 84.
- the process can be started conventionally by a button or switch or may be activated by a change in resistance between the electrodes triggered by skin contact.
- a solid red LED or other indicator will be provided as shown at Box 86 and the device will not be used. If the initialization test is satisfactory, as shown in Diamond 88, proper functioning will be indicated by a green LED as shown at Box 90. Current to the device will be permitted to ramp up and a timer will be started as shown at Box 92. While the current is being delivered through the chemical composition and into the skin, a blinking green LED will be employed, as shown at Box 94.
- Figure 7 illustrates a schematic representation of the current cycle. The current will be ramped up and then held for a time period. Thereafter, the current will be ramped down and the polarity changed.
- a mid-cycle self diagnostic test may be performed by the controller as shown at box 98. If an error is detected, a red LED will be displayed as shown at Box 100 and the procedure will be terminated. If the diagnostic test is satisfactory, as shown at Diamond 102, the procedure will be continued until the time period is completed as shown at Diamond 104. When the time period has been completed, the green light ceases to blink and remains on for a period of time to indicate the end of the procedure as shown at Box 106.
- the patch assembly is removed from the skin and the locket assembly 60 is detached from the patch assembly.
- the locket assembly may be reused.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
- Massaging Devices (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28808809P | 2009-12-18 | 2009-12-18 | |
US12/970,224 US8747383B2 (en) | 2009-12-18 | 2010-12-16 | Process and system for iontophoretic wrinkle reduction |
PCT/US2010/061029 WO2011075646A2 (en) | 2009-12-18 | 2010-12-17 | Process and system for iontophoretic wrinkle reduction |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2512283A2 true EP2512283A2 (en) | 2012-10-24 |
EP2512283A4 EP2512283A4 (en) | 2013-07-31 |
Family
ID=44167938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10838291.2A Ceased EP2512283A4 (en) | 2009-12-18 | 2010-12-17 | Process and system for iontophoretic wrinkle reduction |
Country Status (4)
Country | Link |
---|---|
US (3) | US8747383B2 (en) |
EP (1) | EP2512283A4 (en) |
RU (1) | RU2012130389A (en) |
WO (1) | WO2011075646A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110092881A1 (en) * | 2009-05-08 | 2011-04-21 | Isis Biopolymer Inc. | Iontophoretic device with contact sensor |
SG175341A1 (en) * | 2009-05-08 | 2011-11-28 | Isis Biopolymer Inc | Iontophoretic device with improved counterelectrode |
US8747383B2 (en) | 2009-12-18 | 2014-06-10 | University Medical Pharmaceuticals Corp. | Process and system for iontophoretic wrinkle reduction |
US20130012891A1 (en) * | 2011-07-05 | 2013-01-10 | Yossi Gross | Skin-treatment and drug-delivery devices |
EP3451868A4 (en) * | 2016-05-02 | 2019-12-25 | Purple Inc. | System and method for displaying digital imagery on a digital imagery display locket |
WO2018061596A1 (en) * | 2016-09-27 | 2018-04-05 | パナソニックIpマネジメント株式会社 | Thin film affixing device and thin film formation method |
CN110996717B (en) * | 2017-08-07 | 2023-03-31 | 日本电信电话株式会社 | Sheet-like mask |
US10092478B1 (en) * | 2017-09-06 | 2018-10-09 | Noah Amit | Method and system for treating skin associated with the face and neck |
WO2024080248A1 (en) * | 2022-10-13 | 2024-04-18 | ヤーマン株式会社 | Beauty mask |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996036394A1 (en) * | 1995-05-15 | 1996-11-21 | Alza Corporation | Electrotransport device having reusable controller |
US20040267189A1 (en) * | 2001-10-24 | 2004-12-30 | Daniela Mavor | Device and method for controlled delivery of active substance into the skin |
US20050015042A1 (en) * | 2003-06-30 | 2005-01-20 | Ying Sun | Methods of exfoliating the skin with electricity |
US20070276451A1 (en) * | 2004-12-14 | 2007-11-29 | Stx-Med Sprl | Apparatus For Electro-Inhibition Of Facial Muscles |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
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US4372296A (en) | 1980-11-26 | 1983-02-08 | Fahim Mostafa S | Treatment of acne and skin disorders and compositions therefor |
US4406658A (en) * | 1981-03-06 | 1983-09-27 | Medtronic, Inc. | Iontophoretic device with reversible polarity |
US4702732A (en) * | 1984-12-24 | 1987-10-27 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands |
US4979938A (en) | 1989-05-11 | 1990-12-25 | Iomed, Inc. | Method of iontophoretically treating acne, furuncles and like skin disorders |
US5505949A (en) * | 1994-10-13 | 1996-04-09 | Benitez; Juan E. | Topical treatment for acne |
JP2768456B2 (en) | 1995-12-22 | 1998-06-25 | 株式会社ジャパンギャルズ | Makeup mask |
US6175763B1 (en) * | 1996-03-29 | 2001-01-16 | Alza Corporation | Electrotransport drug delivery device having tactile signaling means |
FR2755372B1 (en) * | 1996-11-07 | 1998-12-24 | Elf Aquitaine | IONOPHORESIS DEVICE COMPRISING AT LEAST ONE MEMBRANE ELECTRODE ASSEMBLY FOR THE TRANSCUTANEOUS ADMINISTRATION OF ACTIVE PRINCIPLES TO A SUBJECT |
US5882677A (en) * | 1997-09-30 | 1999-03-16 | Becton Dickinson And Company | Iontophoretic patch with hydrogel reservoir |
EP1027000A4 (en) * | 1997-10-09 | 2001-09-12 | Camran Nezhat | Methods and systems for organ resection |
US6792306B2 (en) * | 2000-03-10 | 2004-09-14 | Biophoretic Therapeutic Systems, Llc | Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor |
US6590441B2 (en) | 2001-06-01 | 2003-07-08 | Qualcomm Incorporated | System and method for tuning a VLSI circuit |
US7643874B2 (en) * | 2001-10-24 | 2010-01-05 | Power Paper Ltd. | Dermal patch |
US6823202B2 (en) * | 2002-04-01 | 2004-11-23 | Iomed, Inc. | Iontophoretic power supply |
US6866856B2 (en) | 2002-12-31 | 2005-03-15 | Avon Products, Inc. | Compositions and delivery methods for the treatment of wrinkles, fine lines and hyperhidrosis |
KR200327534Y1 (en) | 2003-05-30 | 2003-09-22 | 홍명학 | Apparatus for caring skin |
US7479133B2 (en) | 2003-06-30 | 2009-01-20 | Johnson & Johnson Consumer Companies, Inc. | Methods of treating acne and rosacea with galvanic generated electricity |
NL1023791C2 (en) * | 2003-07-01 | 2005-01-04 | Lely Entpr Ag | Milking installation. |
JP2005245521A (en) | 2004-03-01 | 2005-09-15 | Japan Natural Laboratory Co Ltd | Skin care or beauty system using ion introducer, ultrasonic wave facial treatment device, and cosmetic additives |
US20060100567A1 (en) * | 2004-07-30 | 2006-05-11 | Rocky Mountain Biosystems, Inc | Microsurgical tissue treatment system |
KR200403033Y1 (en) | 2005-09-16 | 2005-12-07 | 이상홍 | Portable skin care device for beauty pack |
US20070092571A1 (en) * | 2005-10-25 | 2007-04-26 | Schur Henry B | Non-irritating formulation and method for the intradermal delivery of substances |
US7945320B2 (en) | 2007-08-17 | 2011-05-17 | Isis Biopolymer, Inc. | Iontophoretic drug delivery system |
JP2011517578A (en) | 2007-12-10 | 2011-06-16 | アイシス バイオポリマー,インク. | Iontophoresis drug administration device and software application |
US20090299267A1 (en) | 2008-05-28 | 2009-12-03 | Isis Biopolymer Llc | Iontophoretic drug delivery system with procedure window |
SG175341A1 (en) | 2009-05-08 | 2011-11-28 | Isis Biopolymer Inc | Iontophoretic device with improved counterelectrode |
US8747383B2 (en) | 2009-12-18 | 2014-06-10 | University Medical Pharmaceuticals Corp. | Process and system for iontophoretic wrinkle reduction |
-
2010
- 2010-12-16 US US12/970,224 patent/US8747383B2/en active Active
- 2010-12-17 RU RU2012130389/12A patent/RU2012130389A/en not_active Application Discontinuation
- 2010-12-17 WO PCT/US2010/061029 patent/WO2011075646A2/en active Application Filing
- 2010-12-17 EP EP10838291.2A patent/EP2512283A4/en not_active Ceased
-
2014
- 2014-06-06 US US14/298,190 patent/US9913977B2/en active Active
-
2018
- 2018-03-12 US US15/918,441 patent/US20180193637A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996036394A1 (en) * | 1995-05-15 | 1996-11-21 | Alza Corporation | Electrotransport device having reusable controller |
US20040267189A1 (en) * | 2001-10-24 | 2004-12-30 | Daniela Mavor | Device and method for controlled delivery of active substance into the skin |
US20050015042A1 (en) * | 2003-06-30 | 2005-01-20 | Ying Sun | Methods of exfoliating the skin with electricity |
US20070276451A1 (en) * | 2004-12-14 | 2007-11-29 | Stx-Med Sprl | Apparatus For Electro-Inhibition Of Facial Muscles |
Non-Patent Citations (1)
Title |
---|
See also references of WO2011075646A2 * |
Also Published As
Publication number | Publication date |
---|---|
US20140288527A1 (en) | 2014-09-25 |
US20180193637A1 (en) | 2018-07-12 |
US20110190724A1 (en) | 2011-08-04 |
US8747383B2 (en) | 2014-06-10 |
RU2012130389A (en) | 2014-01-27 |
WO2011075646A3 (en) | 2011-10-27 |
WO2011075646A2 (en) | 2011-06-23 |
US9913977B2 (en) | 2018-03-13 |
EP2512283A4 (en) | 2013-07-31 |
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