EP2421542A4 - Vecteurs de virus spumeux et leurs procédés d'utilisation - Google Patents

Vecteurs de virus spumeux et leurs procédés d'utilisation

Info

Publication number
EP2421542A4
EP2421542A4 EP10756923.8A EP10756923A EP2421542A4 EP 2421542 A4 EP2421542 A4 EP 2421542A4 EP 10756923 A EP10756923 A EP 10756923A EP 2421542 A4 EP2421542 A4 EP 2421542A4
Authority
EP
European Patent Office
Prior art keywords
foamyvirus
vectors
methods
foamyvirus vectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10756923.8A
Other languages
German (de)
English (en)
Other versions
EP2421542A1 (fr
Inventor
Axel Rethwilm
Dirk Lindemann
Helmut Hanenberg
D Wade Clapp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CLAPP, D. WADE
Hanenberg Helmut
LINDEMANN, DIRK
RETHWILM, AXEL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2421542A1 publication Critical patent/EP2421542A1/fr
Publication of EP2421542A4 publication Critical patent/EP2421542A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/17011—Spumavirus, e.g. chimpanzee foamy virus
    • C12N2740/17041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/17043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/17011—Spumavirus, e.g. chimpanzee foamy virus
    • C12N2740/17051—Methods of production or purification of viral material
    • C12N2740/17052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
EP10756923.8A 2009-03-26 2010-03-26 Vecteurs de virus spumeux et leurs procédés d'utilisation Withdrawn EP2421542A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16367309P 2009-03-26 2009-03-26
PCT/US2010/028854 WO2010111608A1 (fr) 2009-03-26 2010-03-26 Vecteurs de virus spumeux et leurs procédés d'utilisation

Publications (2)

Publication Number Publication Date
EP2421542A1 EP2421542A1 (fr) 2012-02-29
EP2421542A4 true EP2421542A4 (fr) 2013-04-24

Family

ID=42781552

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10756923.8A Withdrawn EP2421542A4 (fr) 2009-03-26 2010-03-26 Vecteurs de virus spumeux et leurs procédés d'utilisation

Country Status (2)

Country Link
EP (1) EP2421542A4 (fr)
WO (1) WO2010111608A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011101060A1 (de) 2011-05-09 2012-11-15 Technische Universität Dresden Retrovirus-Vektorsystem
AU2014314079B2 (en) * 2013-09-02 2020-02-06 Cellectis RNA based method to obtain stably integrated retroviral vectors
CN117247974B (zh) * 2023-09-21 2024-04-05 云舟生物科技(广州)股份有限公司 一种泡沫病毒包装载体系统及其构建方法和试剂盒

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2138584A1 (fr) * 2008-06-27 2009-12-30 Vectoria Forschungsförderungs Verein e.V. Gènes à enveloppe virale mousseuse

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492165B1 (en) * 1997-02-12 2002-12-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Retrovirus isolated from humans
AU2003267976A1 (en) * 2002-06-27 2004-01-19 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention Live replicating spumavirus vector
WO2004050859A2 (fr) * 2002-11-27 2004-06-17 Regents Of The University Of Minnesota Recombinaison homologue dans des cellules souches adultes multipotentes
US7608449B2 (en) * 2003-05-14 2009-10-27 The Regents Of The University Of California Methods and compositions related to high-titer pseudotyped retroviruses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2138584A1 (fr) * 2008-06-27 2009-12-30 Vectoria Forschungsförderungs Verein e.V. Gènes à enveloppe virale mousseuse

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 24 June 2007 (2007-06-24), WU AND GOULD: "Synthetic construct SFV-gag protein (gag) gene, complete cds.", XP002693164, Database accession no. DQ866825 *
FANG Y ET AL: "Higher-Order Oligomerization Targets Plasma Membrane Proteins and HIV Gag to Exosomes", PLOS BIOLOGY, vol. 5, no. 6, 1 June 2007 (2007-06-01), pages 1267 - 1283, XP008136116, ISSN: 1544-9173, DOI: 10.1371/JOURNAL.PBIO.0050158 *
JOSEPHSON NEIL C ET AL: "Transduction of long-term and mobilized peripheral blood-derived NOD/SCID repopulating cells by foamy virus vectors.", HUMAN GENE THERAPY, vol. 15, no. 1, January 2004 (2004-01-01), pages 87 - 92, XP002693163, ISSN: 1043-0342 *
RETHWILM AXEL: "Foamy virus vectors: an awaited alternative to gammaretro- and lentiviral vectors", CURRENT GENE THERAPY, vol. 7, no. 4, 1 August 2007 (2007-08-01), pages 261 - 271, XP009161696, ISSN: 1566-5232 *
See also references of WO2010111608A1 *
TROBRIDGE GRANT ET AL: "Improved foamy virus vectors with minimal viral sequences.", MOLECULAR THERAPY, vol. 6055055113, no. 3, September 2002 (2002-09-01), pages 321 - 328, XP055055113, ISSN: 1525-0016 *
Y. LI ET AL: "Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo", BLOOD, vol. 113, no. 10, 5 March 2009 (2009-03-05), pages 2342 - 2351, XP055055184, ISSN: 0006-4971, DOI: 10.1182/blood-2008-07-168138 *

Also Published As

Publication number Publication date
WO2010111608A1 (fr) 2010-09-30
EP2421542A1 (fr) 2012-02-29

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: RETHWILM, AXEL

Owner name: CLAPP, D. WADE

Owner name: HANENBERG, HELMUT

Owner name: LINDEMANN, DIRK

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: C12N 15/867 20060101AFI20130314BHEP

Ipc: A61K 48/00 20060101ALI20130314BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20130325

17Q First examination report despatched

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Effective date: 20150728