EP2337570A4 - Zusammensetzungen und verfahren zur hemmung des eintritts eines hepatischen virus - Google Patents

Zusammensetzungen und verfahren zur hemmung des eintritts eines hepatischen virus

Info

Publication number
EP2337570A4
EP2337570A4 EP09812100A EP09812100A EP2337570A4 EP 2337570 A4 EP2337570 A4 EP 2337570A4 EP 09812100 A EP09812100 A EP 09812100A EP 09812100 A EP09812100 A EP 09812100A EP 2337570 A4 EP2337570 A4 EP 2337570A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
inhibiting entry
hepatic virus
hepatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09812100A
Other languages
English (en)
French (fr)
Other versions
EP2337570A1 (de
Inventor
Susan L Uprichard
Bruno Sainz Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
Original Assignee
University of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois filed Critical University of Illinois
Publication of EP2337570A1 publication Critical patent/EP2337570A1/de
Publication of EP2337570A4 publication Critical patent/EP2337570A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP09812100A 2008-09-02 2009-09-01 Zusammensetzungen und verfahren zur hemmung des eintritts eines hepatischen virus Withdrawn EP2337570A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9354908P 2008-09-02 2008-09-02
US16989909P 2009-04-16 2009-04-16
PCT/US2009/055575 WO2010027951A1 (en) 2008-09-02 2009-09-01 Compositions and methods for inhibiting entry of a hepatic virus

Publications (2)

Publication Number Publication Date
EP2337570A1 EP2337570A1 (de) 2011-06-29
EP2337570A4 true EP2337570A4 (de) 2012-03-28

Family

ID=41797442

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09812100A Withdrawn EP2337570A4 (de) 2008-09-02 2009-09-01 Zusammensetzungen und verfahren zur hemmung des eintritts eines hepatischen virus

Country Status (4)

Country Link
US (1) US8673288B2 (de)
EP (1) EP2337570A4 (de)
CA (1) CA2735811A1 (de)
WO (1) WO2010027951A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127511A (zh) * 2013-02-07 2013-06-05 中美华世通生物医药科技（武汉）有限公司 治疗丙型肝炎的新型药物组合物
CN103127512A (zh) * 2013-02-07 2013-06-05 中美华世通生物医药科技（武汉）有限公司 治疗乙型肝炎的新型药物组合物
EP3455218A4 (de) 2016-05-10 2019-12-18 C4 Therapeutics, Inc. Mit c3-kohlenstoff verknüpfte glutarimiddegronimere zum zielproteinabbau
WO2017197055A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Heterocyclic degronimers for target protein degradation
WO2017197036A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
EP3912624A1 (de) * 2020-05-18 2021-11-24 Virtexx Verbindungen und verfahren zur behandlung von umhüllten vireninfektionen

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008033466A2 (en) * 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions and methods for treatment of viral diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301543C (en) * 1997-10-07 2005-05-17 Boehringer Ingelheim (Canada) Ltd. Azetidinone derivatives for the treatment of hcmv infections
EP1545479B1 (de) * 2002-07-30 2010-10-27 Karykion Inc. Zusammensetzungen aus ezetimib und verfahren zur behandlung von mit cholesterin zusammenhängenden gutartigen und bösartigen tumoren

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008033466A2 (en) * 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions and methods for treatment of viral diseases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
TEMEL RYAN E ET AL: "Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetirnibe", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US, vol. 117, no. 7, 1 July 2007 (2007-07-01), pages 1968 - 1978, XP009156407, ISSN: 0021-9738, DOI: 10.1172/JCI30060 *
YUKI IWAYANAGI ET AL: "HNF4Î+- is a Crucial Modulator of the Cholesterol-Dependent Regulation of NPC1L1", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 25, no. 5, 14 December 2007 (2007-12-14), pages 1134 - 1141, XP019613072, ISSN: 1573-904X *

Also Published As

Publication number Publication date
US8673288B2 (en) 2014-03-18
US20110171177A1 (en) 2011-07-14
CA2735811A1 (en) 2010-03-11
WO2010027951A1 (en) 2010-03-11
EP2337570A1 (de) 2011-06-29

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