EP2329024A4 - Arn endogène court en épingle à cheveux et son utilisation - Google Patents

Arn endogène court en épingle à cheveux et son utilisation

Info

Publication number
EP2329024A4
EP2329024A4 EP08784123A EP08784123A EP2329024A4 EP 2329024 A4 EP2329024 A4 EP 2329024A4 EP 08784123 A EP08784123 A EP 08784123A EP 08784123 A EP08784123 A EP 08784123A EP 2329024 A4 EP2329024 A4 EP 2329024A4
Authority
EP
European Patent Office
Prior art keywords
same
hairpin rna
short hairpin
endogenous short
endogenous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08784123A
Other languages
German (de)
English (en)
Other versions
EP2329024A1 (fr
Inventor
Robert C Zhao
James Q Yin
Chunjing Bian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Basic Medical Sciences of AMMS
Institute of Basic Medical Sciences of CAMS
Original Assignee
Institute of Basic Medical Sciences of AMMS
Institute of Basic Medical Sciences of CAMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Basic Medical Sciences of AMMS, Institute of Basic Medical Sciences of CAMS filed Critical Institute of Basic Medical Sciences of AMMS
Publication of EP2329024A1 publication Critical patent/EP2329024A1/fr
Publication of EP2329024A4 publication Critical patent/EP2329024A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP08784123A 2008-08-25 2008-08-25 Arn endogène court en épingle à cheveux et son utilisation Withdrawn EP2329024A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2008/072133 WO2010022553A1 (fr) 2008-08-25 2008-08-25 Arn endogène court en épingle à cheveux et son utilisation

Publications (2)

Publication Number Publication Date
EP2329024A1 EP2329024A1 (fr) 2011-06-08
EP2329024A4 true EP2329024A4 (fr) 2012-02-22

Family

ID=41720773

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08784123A Withdrawn EP2329024A4 (fr) 2008-08-25 2008-08-25 Arn endogène court en épingle à cheveux et son utilisation

Country Status (4)

Country Link
EP (1) EP2329024A4 (fr)
CN (1) CN102131929A (fr)
AU (1) AU2008361210A1 (fr)
WO (1) WO2010022553A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103088065B (zh) * 2013-01-25 2014-12-10 北京银杏德济生物技术有限公司 一种能够大规模并快速高纯度地诱导间充质干细胞转决定成造血干细胞的方法
EP3184095A1 (fr) * 2013-05-23 2017-06-28 IP Gesellschaft für Management mbH Unitées d'administration comprennante une polymorphe 1 de 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide
CN116904469B (zh) * 2023-09-12 2024-01-23 首都儿科研究所 一种p300蛋白表达的抑制剂和制备方法及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040265849A1 (en) * 2002-11-22 2004-12-30 Applera Corporation Genetic polymorphisms associated with Alzheimer's disease, methods of detection and uses thereof
WO2009017670A2 (fr) * 2007-07-26 2009-02-05 University Of Massachusetts Effecteurs d'extinction épigénétique à médiation par ras et leurs utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004286231B2 (en) * 2003-10-22 2009-09-10 Aventis Pharmaceuticals Inc. Retroviral vectors for delivery of interfering RNA
CN101024830A (zh) * 2007-02-01 2007-08-29 王鸿艳 一种ShRNA的克隆方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040265849A1 (en) * 2002-11-22 2004-12-30 Applera Corporation Genetic polymorphisms associated with Alzheimer's disease, methods of detection and uses thereof
WO2009017670A2 (fr) * 2007-07-26 2009-02-05 University Of Massachusetts Effecteurs d'extinction épigénétique à médiation par ras et leurs utilisations

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
A. BAVNER: "A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP", EMBO REPORTS, vol. 3, no. 5, 15 May 2002 (2002-05-15), pages 478 - 484, XP055010059, ISSN: 1469-221X, DOI: 10.1093/embo-reports/kvf087 *
BIAN CHUNJING ET AL: "An endogenous short hairpin RNA shr337 induces the formation of hematopoietic stem cells from messenchymal stem cells in human bone marrow", EXPERIMENTAL HEMATOLOGY; 37TH ANNUAL SCIENTIFIC MEETING OF THE INTERNATIONAL-SOCIETY-FOR-EXPERIMENTAL-HEMATOLOGY/6TH INTERNAT; BOSTON, MA, USA; JULY 09 -12, 2008, ELSEVIER INC, US, vol. 36, no. 7 supplement 1, 1 July 2008 (2008-07-01), pages S47 - S48, XP008144300, ISSN: 0301-472X, [retrieved on 20080620], DOI: 10.1016/J.EXPHEM.2008.05.007 *
BIAN CHUNJING ET AL: "An endogenous short hairpin RNA shr337 induces the formation of hematopoietic stem cells from messenchymal stem cells in human bone marrow", EXPERIMENTAL HEMATOLOGY; 37TH ANNUAL SCIENTIFIC MEETING OF THE INTERNATIONAL-SOCIETY-FOR-EXPERIMENTAL-HEMATOLOGY/6TH INTERNAT; BOSTON, MA, USA; JULY 09 -12, 2008, ELSEVIER INC, US, vol. 36, no. 7 supplement 1, 1 July 2008 (2008-07-01), pages S6, XP008144301, ISSN: 0301-472X, DOI: 10.1016/J.EXPHEM.2008.05.007 *
GU, TONGJUN ET AL.: "A novel class of endogenous shRNAs in human cells", NATURE PRECEDINGS, 22 January 2008 (2008-01-22), XP002661697, Retrieved from the Internet <URL:http://precedings.nature.com/documents/1531/version/1/files/npre20081531-1.pdf> [retrieved on 20111020] *
See also references of WO2010022553A1 *
WANG ET AL: "Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells", EXPERIMENTAL HEMATOLOGY, ELSEVIER INC, US, vol. 36, no. 2, 26 November 2007 (2007-11-26), pages 128 - 139, XP022425429, ISSN: 0301-472X, DOI: 10.1016/J.EXPHEM.2007.09.004 *
ZOU GANG-MING ET AL: "Reduction of Shp-2 expression by small interfering RNA reduces murine embryonic stem cell-derived in vitro hematopoietic differentiation", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, vol. 24, no. 3, 1 March 2006 (2006-03-01), pages 587 - 594, XP002489842, ISSN: 1066-5099, DOI: 10.1634/STEMCELLS.2005-0272 *

Also Published As

Publication number Publication date
WO2010022553A1 (fr) 2010-03-04
EP2329024A1 (fr) 2011-06-08
AU2008361210A1 (en) 2010-03-04
CN102131929A (zh) 2011-07-20

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 7/00 20060101ALI20120117BHEP

Ipc: A61K 31/7105 20060101ALI20120117BHEP

Ipc: C12N 15/113 20100101AFI20120117BHEP

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