EP2236199A3 - Process and installation for automatic sterile dosing and mixing of infusions - Google Patents

Process and installation for automatic sterile dosing and mixing of infusions Download PDF

Info

Publication number
EP2236199A3
EP2236199A3 EP10158580A EP10158580A EP2236199A3 EP 2236199 A3 EP2236199 A3 EP 2236199A3 EP 10158580 A EP10158580 A EP 10158580A EP 10158580 A EP10158580 A EP 10158580A EP 2236199 A3 EP2236199 A3 EP 2236199A3
Authority
EP
European Patent Office
Prior art keywords
mixing
mixing chamber
computer
suction syringe
gripper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10158580A
Other languages
German (de)
French (fr)
Other versions
EP2236199B1 (en
EP2236199A2 (en
Inventor
Ludger Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP2236199A2 publication Critical patent/EP2236199A2/en
Publication of EP2236199A3 publication Critical patent/EP2236199A3/en
Application granted granted Critical
Publication of EP2236199B1 publication Critical patent/EP2236199B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/85—Mixing plants with mixing receptacles or mixing tools that can be indexed into different working positions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/002—Compounding apparatus specially for enteral or parenteral nutritive solutions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Die Einrichtung besteht aus einem Computer (6) mit Roboter-Steuersoftware, einem Lagerraum (1) für Edukte mit Regal-Tabletts (4), einem Mischraum (10) der Reinraumklasse A mit ständiger Durchlüftung, mit einem Regaltablett (4) und einer Mischflaschenwaage (17) und einem Entsorgungsbehälter, und einem Ausgaberaum (13) für die fertigen Produkte. Im Ausgaberaum (13) befindet sich ein Karussell (19) mit Aufnahmebehältern (20). Der Mischraum (10) enthält einen Roboter mit einem Greifer (15) und mit einer Saugspritze (16). Mit dem Greifer (15) können computergesteuert bestimmte Fläschchen (3) vom Lagerraum (1) in den Mischraum (10) geholt werden. Die Saugspritze (16) kann computergesteuert Edukte aus den im Mischraum (1) abgestellten Fläschchen (3) saugen und in ein Mischfläschchen (3) auf der Mischflaschenwaage (17) im Mischraum (10) ausstossen. Mit der Saugspritze (16) können ausserdem Mischungen aus dem Mischfläschchen (3) gesaugt werden und dann in einen bestimmten Aufnahmebehälter (20) für das fertige Produkt ausgestossen werden. Die Dosierung und Mischung von Wirkstoffen wird dadurch sicherer, schneller und ökonomischer. Ausserdem ist jede Gefährdung des Personals durch Stiche und Kontaminationen ausgeschlossen.

Figure imgaf001
The device consists of a computer (6) with robot control software, a storage room (1) for educts with shelf trays (4), a mixing chamber (10) of cleanroom class A with constant ventilation, with a shelf tray (4) and a mixing bottle scale (17) and a disposal container, and a discharge space (13) for the finished products. In the output space (13) is a carousel (19) with receptacles (20). The mixing chamber (10) contains a robot with a gripper (15) and with a suction syringe (16). With the gripper (15) computer controlled certain vials (3) from the storage room (1) in the mixing chamber (10) can be fetched. The suction syringe (16) can computer-controlled suck starting materials from the vials (3) parked in the mixing chamber (1) and eject into a mixing vial (3) on the mixing bottle balance (17) in the mixing chamber (10). With the suction syringe (16) also mixtures of the mixing vial (3) can be sucked and then ejected into a specific receptacle (20) for the finished product. The dosage and mixture of active ingredients is safer, faster and more economical. In addition, any danger to personnel caused by stabs and contamination is excluded.
Figure imgaf001
EP10158580A 2009-04-01 2010-03-31 Process and installation for automatic sterile dosing and mixing of infusions Not-in-force EP2236199B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH00537/09A CH700740A2 (en) 2009-04-01 2009-04-01 Method and apparatus for automated sterile dosing and mixing infusions.

Publications (3)

Publication Number Publication Date
EP2236199A2 EP2236199A2 (en) 2010-10-06
EP2236199A3 true EP2236199A3 (en) 2010-10-20
EP2236199B1 EP2236199B1 (en) 2012-05-30

Family

ID=42357733

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10158580A Not-in-force EP2236199B1 (en) 2009-04-01 2010-03-31 Process and installation for automatic sterile dosing and mixing of infusions

Country Status (2)

Country Link
EP (1) EP2236199B1 (en)
CH (1) CH700740A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102072025B1 (en) * 2012-10-25 2020-01-31 가부시키가이샤 유야마 세이사쿠쇼 Co-infusion device
DE102017005835B4 (en) * 2017-06-20 2020-04-02 Diehl Metering Gmbh Device for the mobile determination of a property of a liquid, solid or gaseous sample
US11944588B2 (en) 2018-05-11 2024-04-02 Bristol-Myers Squibb Company Devices and systems for delivery of combination therapies
DE102019214849A1 (en) * 2019-09-27 2021-04-01 Bausch + Ströbel Maschinenfabrik Ilshofen GmbH + Co. KG PRODUCTION EQUIPMENT, ESPECIALLY FOR THE PHARMACEUTICAL INDUSTRY
CN115487716B (en) * 2022-11-22 2023-03-10 莱州市文昌路畜牧兽医站 Animal doctor uses dispensing device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5431201A (en) * 1993-12-03 1995-07-11 Technology 2000 Incororated Robotic admixture system
WO2002049761A2 (en) * 2000-12-18 2002-06-27 Protedyne Corporation Automated laboratory system and method
EP1291658A1 (en) * 2001-09-07 2003-03-12 The Automation Partnership (Cambridge) Limited Pipette head apparatus for robot
WO2006124211A2 (en) * 2005-05-16 2006-11-23 Intelligent Hospital Systems Ltd. Automated pharmacy admixture system (apas)
WO2008012596A2 (en) * 2006-07-26 2008-01-31 Health Robotics S.R.L. Machine for the preparation of pharmaceutical products
US20080169044A1 (en) * 2006-10-20 2008-07-17 Forhealth Technologies, Inc. Automated drug preparation apparatus including syringe loading, preparation and filling
WO2009147252A1 (en) * 2008-06-06 2009-12-10 Pharmed S.A.M. Automated workstation for the secure preparation of a final product for medical or pharmaceutical use

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5431201A (en) * 1993-12-03 1995-07-11 Technology 2000 Incororated Robotic admixture system
WO2002049761A2 (en) * 2000-12-18 2002-06-27 Protedyne Corporation Automated laboratory system and method
EP1291658A1 (en) * 2001-09-07 2003-03-12 The Automation Partnership (Cambridge) Limited Pipette head apparatus for robot
WO2006124211A2 (en) * 2005-05-16 2006-11-23 Intelligent Hospital Systems Ltd. Automated pharmacy admixture system (apas)
WO2008012596A2 (en) * 2006-07-26 2008-01-31 Health Robotics S.R.L. Machine for the preparation of pharmaceutical products
US20080169044A1 (en) * 2006-10-20 2008-07-17 Forhealth Technologies, Inc. Automated drug preparation apparatus including syringe loading, preparation and filling
WO2009147252A1 (en) * 2008-06-06 2009-12-10 Pharmed S.A.M. Automated workstation for the secure preparation of a final product for medical or pharmaceutical use

Also Published As

Publication number Publication date
EP2236199B1 (en) 2012-05-30
EP2236199A2 (en) 2010-10-06
CH700740A2 (en) 2010-10-15

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