EP2234622A4 - Verfahren zur erhöhung von muskelleistung und muskeltonus - Google Patents

Verfahren zur erhöhung von muskelleistung und muskeltonus

Info

Publication number
EP2234622A4
EP2234622A4 EP08866040A EP08866040A EP2234622A4 EP 2234622 A4 EP2234622 A4 EP 2234622A4 EP 08866040 A EP08866040 A EP 08866040A EP 08866040 A EP08866040 A EP 08866040A EP 2234622 A4 EP2234622 A4 EP 2234622A4
Authority
EP
European Patent Office
Prior art keywords
tone
methods
muscle performance
enhancing muscle
enhancing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08866040A
Other languages
English (en)
French (fr)
Other versions
EP2234622A2 (de
Inventor
Ronald M Evans
Vihang A Narkar
Reuben J Shaw
Michael Downes
Ruth T Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/966,851 external-priority patent/US20080187928A1/en
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Publication of EP2234622A2 publication Critical patent/EP2234622A2/de
Publication of EP2234622A4 publication Critical patent/EP2234622A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP08866040A 2007-12-28 2008-12-29 Verfahren zur erhöhung von muskelleistung und muskeltonus Withdrawn EP2234622A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/966,851 US20080187928A1 (en) 2006-12-29 2007-12-28 Methods for enhancing exercise performance
PCT/US2007/089124 WO2008083330A2 (en) 2006-12-29 2007-12-28 Methods for enhancing exercise performance
US8084108P 2008-07-15 2008-07-15
PCT/US2008/088466 WO2009086526A2 (en) 2007-12-28 2008-12-29 Methods for enhancing muscle performance and tone

Publications (2)

Publication Number Publication Date
EP2234622A2 EP2234622A2 (de) 2010-10-06
EP2234622A4 true EP2234622A4 (de) 2011-03-09

Family

ID=40825106

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08866040A Withdrawn EP2234622A4 (de) 2007-12-28 2008-12-29 Verfahren zur erhöhung von muskelleistung und muskeltonus

Country Status (5)

Country Link
EP (1) EP2234622A4 (de)
JP (1) JP2011507970A (de)
AU (1) AU2008345009A1 (de)
CA (1) CA2710764A1 (de)
WO (1) WO2009086526A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2114396A4 (de) 2006-12-29 2010-03-10 Salk Inst For Biological Studi Verfahren zur verbesserung der trainingsleistung
CA2753876A1 (en) * 2009-03-20 2010-09-23 The Salk Institute For Biological Studies Methods for modulating circadian rhythms
KR101698201B1 (ko) * 2010-05-20 2017-01-19 (주)뉴트리 판두라틴 유도체 또는 보에센베르기아 판두라타 추출물을 포함하는 근육 증가 촉진, 항-피로 및 운동수행능력 향상용 조성물
CA2809958A1 (en) 2010-08-31 2012-03-08 Snu R & Db Foundation Use of the fetal reprogramming of a ppar ? agonist
US20140147431A1 (en) * 2010-09-20 2014-05-29 The Regents Of The University Of California Compositions and Methods for Modulating Desnutrin-Mediated Adipocyte Lipolysis
EP2554182A1 (de) * 2011-08-03 2013-02-06 Universitat Pompeu-Fabra Säugersestrine zur Behandlung von Muskelschwund
US20140186306A1 (en) * 2012-09-28 2014-07-03 Paul Ronald Plante Novel ampk agonist compositions and methods of use
CA2908695A1 (en) 2013-04-05 2014-10-09 Salk Institute For Biological Studies Ppar agonists
CA2923422C (en) * 2013-09-09 2021-09-07 Vtv Therapeutics Llc Use of a ppar-delta agonist for treating muscle atrophy
WO2016057322A1 (en) 2014-10-08 2016-04-14 Salk Institute For Biological Studies Ppar agonists and methods of use thereof
WO2016057656A1 (en) 2014-10-08 2016-04-14 Mitobridge, Inc. Ppar-delta agonists for use for treating mitochondrial, vascular, muscular, and demyelinating diseases
CN108349904B (zh) 2015-10-07 2021-08-31 米托布里奇公司 Ppar激动剂、化合物、药物组合物及其使用方法
MX2018012538A (es) 2016-04-13 2019-02-25 Mitobridge Inc Agonistas del receptor activado por proliferador de peroxisoma (ppar), compuestos, composiciones farmaceuticas y metodos para usar los mismos.
WO2020085393A1 (ja) 2018-10-23 2020-04-30 国立研究開発法人科学技術振興機構 ＰＰＡＲδ活性化剤
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001093874A1 (en) * 2000-06-09 2001-12-13 Brigham Young University Method of treatment of obesity and paralyzed muscle and ergogenic aids
WO2008083330A2 (en) * 2006-12-29 2008-07-10 The Salk Institute For Biological Studies Methods for enhancing exercise performance

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050233328A1 (en) * 2001-12-03 2005-10-20 Constance Berghs Methods of identifying compounds that modulate protein activity
US20040259948A1 (en) * 2003-01-10 2004-12-23 Peter Tontonoz Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
WO2005003766A2 (en) * 2003-06-13 2005-01-13 Whitehead Institute For Biomedical Research Methods of regulating metabolism and mitochondrial function
WO2005063232A1 (en) * 2003-12-30 2005-07-14 Md Bioalpha Co., Ltd. Obesity and metabolic syndrome treatment with tanshinone derivatives which increase metabolic activity
WO2007006135A1 (en) * 2005-07-07 2007-01-18 H3 Formulations Ltd. Dietary supplement for enhancing skeletal muscle mass, decreasing muscle protein degradation, downregulation of muscle catabolism pathways, and decreasing catabolism of muscle cells
US20070265223A1 (en) * 2006-03-10 2007-11-15 Ikaria, Inc. Compositions and methods of enhancing survivability and reducing injury of cells, tissues, organs, and organisms under hypoxic or ischemic conditions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001093874A1 (en) * 2000-06-09 2001-12-13 Brigham Young University Method of treatment of obesity and paralyzed muscle and ergogenic aids
WO2008083330A2 (en) * 2006-12-29 2008-07-10 The Salk Institute For Biological Studies Methods for enhancing exercise performance

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KRAEMER DAVID KITZ ET AL: "Role of AMP kinase and PPAR delta in the regulation of lipid and glucose metabolism in human skeletal muscle", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, INC, US, vol. 282, no. 27, 1 July 2007 (2007-07-01), pages 19313 - 19320, XP009143817, ISSN: 0021-9258 *
NARKAR V A ET AL: "AMPK and PPAR.beta. Agonists Are Exercise Mimetics", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 134, no. 3, 8 August 2008 (2008-08-08), pages 405 - 415, XP002565786, ISSN: 0092-8674, [retrieved on 20080731], DOI: 10.1016/J.CELL.2008.06.051 *
WANG YONG-XU ET AL: "Regulation of muscle fiber type and running endurance by PPARdelta", PLOS BIOLOGY, PUBLIC LIBRARY OF SCIENCE, US, vol. 2, no. 10, 1 October 2004 (2004-10-01), pages E294, XP002560117, ISSN: 1544-9173, DOI: 10.1371/JOURNAL.PBIO.0020294 *

Also Published As

Publication number Publication date
WO2009086526A2 (en) 2009-07-09
EP2234622A2 (de) 2010-10-06
AU2008345009A1 (en) 2009-07-09
JP2011507970A (ja) 2011-03-10
CA2710764A1 (en) 2009-07-09
WO2009086526A3 (en) 2009-09-03

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20100720

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AX Request for extension of the european patent

Extension state: AL BA MK RS

RIN1 Information on inventor provided before grant (corrected)

Inventor name: YU, RUTH, T.

Inventor name: DOWNES, MICHAEL

Inventor name: SHAW, REUBEN, J.

Inventor name: NARKAR, VIHANG, A.

Inventor name: EVANS, RONALD, M.

A4 Supplementary search report drawn up and despatched

Effective date: 20110207

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 21/06 20060101ALI20110201BHEP

Ipc: A61K 45/06 20060101ALI20110201BHEP

Ipc: A61K 31/00 20060101ALI20110201BHEP

Ipc: A61K 31/426 20060101ALI20110201BHEP

Ipc: A61K 31/7056 20060101ALI20110201BHEP

Ipc: A61K 31/70 20060101AFI20091125BHEP

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