EP2199801A3 - Biomarqueurs pour la détection précoce du cancer des ovaires - Google Patents
Biomarqueurs pour la détection précoce du cancer des ovaires Download PDFInfo
- Publication number
- EP2199801A3 EP2199801A3 EP10003541A EP10003541A EP2199801A3 EP 2199801 A3 EP2199801 A3 EP 2199801A3 EP 10003541 A EP10003541 A EP 10003541A EP 10003541 A EP10003541 A EP 10003541A EP 2199801 A3 EP2199801 A3 EP 2199801A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- biomarkers
- serum sample
- ovarian cancer
- early detection
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/79—Transferrins, e.g. lactoferrins, ovotransferrins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58800704P | 2004-07-14 | 2004-07-14 | |
US67448905P | 2005-04-25 | 2005-04-25 | |
EP05771584A EP1789805B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueur pour détecter de manière précoce un cancer des ovaires |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05771584.9 Division | 2005-07-14 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2199801A2 EP2199801A2 (fr) | 2010-06-23 |
EP2199801A3 true EP2199801A3 (fr) | 2010-08-25 |
EP2199801B1 EP2199801B1 (fr) | 2013-05-29 |
Family
ID=35406265
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10003541.9A Not-in-force EP2199801B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueurs pour la détection précoce du cancer des ovaires |
EP14183123.0A Not-in-force EP2848942B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueurs pour la détection précoce du cancer des ovaires |
EP10009544.7A Not-in-force EP2261672B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueur pour détecter de manière précoce un cancer des ovaires |
EP17158112.7A Withdrawn EP3203241A1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueurs pour la détection précoce du cancer des ovaires |
EP05771584A Not-in-force EP1789805B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueur pour détecter de manière précoce un cancer des ovaires |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14183123.0A Not-in-force EP2848942B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueurs pour la détection précoce du cancer des ovaires |
EP10009544.7A Not-in-force EP2261672B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueur pour détecter de manière précoce un cancer des ovaires |
EP17158112.7A Withdrawn EP3203241A1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueurs pour la détection précoce du cancer des ovaires |
EP05771584A Not-in-force EP1789805B1 (fr) | 2004-07-14 | 2005-07-14 | Biomarqueur pour détecter de manière précoce un cancer des ovaires |
Country Status (6)
Country | Link |
---|---|
US (3) | US8323915B2 (fr) |
EP (5) | EP2199801B1 (fr) |
AT (1) | ATE481645T1 (fr) |
DE (1) | DE602005023629D1 (fr) |
DK (1) | DK2199801T3 (fr) |
WO (1) | WO2006019906A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9488655B2 (en) * | 2004-07-14 | 2016-11-08 | The Regents Of The University Of California | Biomarkers for detection of early- and late-stage endometrial cancer |
WO2012047930A2 (fr) | 2010-10-04 | 2012-04-12 | The Regents Of The University Of California | Compositions et procédés de traitement de cancers gynécologiques |
CA2611340A1 (fr) | 2005-06-22 | 2007-01-04 | The Johns Hopkins University | Bio-marqueur pour cancer ovarien : proteines apparentees a ctap3 |
JP2010522882A (ja) | 2007-03-27 | 2010-07-08 | ヴァーミリオン インコーポレイテッド | 卵巣癌のバイオマーカー |
KR100997463B1 (ko) * | 2007-04-30 | 2010-11-30 | (주)예비티 | 난소암 진단용 조성물, 그 키트 및 진단 방법 |
WO2009058331A2 (fr) * | 2007-10-29 | 2009-05-07 | Vermilllion, Inc. | Biomarqueurs permettant la détection du cancer des ovaires à un stade précoce |
WO2011128892A2 (fr) * | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Formes modifiées de protéine b immunogène de surface pneumococcique (psipb) |
AU2011316844A1 (en) * | 2010-10-22 | 2013-06-06 | Vermillion, Inc. | Prognostic biomarkers in patients with ovarian cancer |
EP2718395B1 (fr) * | 2011-06-10 | 2018-02-28 | Basf Se | Nouveau dispositif d'éclairage comportant un convertisseur de couleurs |
AU2012301955A1 (en) | 2011-08-29 | 2014-03-06 | The Regents Of The University Of California | Use of HDL-related molecules to treat and prevent proinflammatory conditions |
US9789175B2 (en) * | 2013-03-15 | 2017-10-17 | The Trustees Of The University Of Pennsylvania | Synthetic immunogens for prophylaxis or treatment of tuberculosis |
US20150153348A1 (en) * | 2013-12-04 | 2015-06-04 | Vermillion, Inc. | BIOMARKERS FOR OVARIAN CANCER: Beta 2 MICROGLOBULIN |
RU2576821C2 (ru) * | 2014-06-30 | 2016-03-10 | Федеральное государственное бюджетное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения Российской Федерации" (ФГБУ "МНИОИ им. П.А. Герцена" Минздрава России) | Способ определения эффективности консервативного лечения рака не увеличенных яичников |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027216A1 (en) * | 2001-07-02 | 2003-02-06 | Kiernan Urban A. | Analysis of proteins from biological fluids using mass spectrometric immunoassay |
WO2004012588A2 (fr) * | 2002-08-06 | 2004-02-12 | The Johns Hopkins University | Utilisation de biomarqueurs dans la detection du cancer de l'ovaire |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
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US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
US4918164A (en) | 1987-09-10 | 1990-04-17 | Oncogen | Tumor immunotherapy using anti-idiotypic antibodies |
US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
DK145385D0 (da) * | 1985-03-29 | 1985-04-01 | Novo Industri As | Monoklonalt antistof til immunkemisk analyse |
GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
US5114863A (en) * | 1986-09-30 | 1992-05-19 | Board Of Supervisors Of Louisiana State University & Agricultural & Mechanical College | Immunosorbant assay for α-1-antitrypsin, kit employing said assay, monoclonal antibody to α-1-antitrypsin, and hybridoma for producing said monoclonal antibody |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
WO1989001973A2 (fr) | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Virus variolique recombinant d'immunisation contre des antigenes associes a une tumeur |
EP0398880A4 (en) | 1988-01-04 | 1990-12-27 | E.I. Du Pont De Nemours And Company | Multiple stage affinity process for isolation of specific cells from a cell mixture |
US5215926A (en) | 1988-06-03 | 1993-06-01 | Cellpro, Inc. | Procedure for designing efficient affinity cell separation processes |
AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
US5536475A (en) | 1988-10-11 | 1996-07-16 | Baxter International Inc. | Apparatus for magnetic cell separation |
WO1991002805A2 (fr) | 1989-08-18 | 1991-03-07 | Viagene, Inc. | Retrovirus de recombinaison apportant des constructions de vecteur a des cellules cibles |
SE8904007D0 (sv) * | 1989-11-28 | 1989-11-28 | Ferring Ab | Monoklona antikroppar och diagnostiseringsmetod |
WO1991016116A1 (fr) | 1990-04-23 | 1991-10-31 | Cellpro Incorporated | Dispositif et procede d'immunoselection |
SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
DK0553288T3 (da) | 1990-10-18 | 1997-12-29 | Cellpro Inc | Apparat og fremgangsmåde til udskillelse af partikler ved brug af en eftergivende beholder |
US5240856A (en) | 1991-10-23 | 1993-08-31 | Cellpro Incorporated | Apparatus for cell separation |
US6277603B1 (en) | 1991-12-24 | 2001-08-21 | Isis Pharmaceuticals, Inc. | PNA-DNA-PNA chimeric macromolecules |
US5700922A (en) | 1991-12-24 | 1997-12-23 | Isis Pharmaceuticals, Inc. | PNA-DNA-PNA chimeric macromolecules |
WO1997024447A1 (fr) | 1996-01-02 | 1997-07-10 | Chiron Corporation | Immunostimulation a mediation par cellules dendritiques modifiees par des genes |
EP2314625B1 (fr) | 1996-12-03 | 2014-05-07 | Amgen Fremont Inc. | Mammifères transgèniques obtenus par génie génétique contenant des loci des immunoglobulines humaines qui comprennent plusieurs régions de VH et de Vkappa, et anticorps aussi obtenus |
US5891641A (en) * | 1997-02-21 | 1999-04-06 | The Regents Of The University Of California | Assay for disease related conformation of a protein |
NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
US5955582A (en) * | 1997-09-26 | 1999-09-21 | Beckman Coulter, Inc. | Antibody against a 3-aminophenylboronic-glycated protein complex and its use in an immunoassay |
GB9805877D0 (en) * | 1998-03-20 | 1998-05-13 | Imp Cancer Res Tech | Cancer |
US6828114B1 (en) * | 1998-12-22 | 2004-12-07 | Daiichi Pure Chemicals Co., Ltd. | Monoclonal antibody against apolipoprotein A-I |
EP1384079A2 (fr) * | 2001-05-02 | 2004-01-28 | Oxford GlycoSciences (UK) Limited | Proteines, genes et leur utilisation dans le cadre du diagnostic et du traitement du cancer du sein |
US20050214760A1 (en) * | 2002-01-07 | 2005-09-29 | Johns Hopkins University | Biomarkers for detecting ovarian cancer |
WO2004001010A2 (fr) * | 2002-06-21 | 2003-12-31 | Ptc Therapeutics, Inc. | Methodes permettant d'identifier de petites molecules modulant une terminaison de traduction prematuree et une degradation d'arnm a mediation non sens |
DE60305919T2 (de) * | 2002-06-28 | 2007-01-18 | Domantis Limited, Cambridge | Dual-specifische liganden mit erhöhter halbwertszeit |
US7927791B2 (en) * | 2002-07-24 | 2011-04-19 | Ptc Therapeutics, Inc. | Methods for identifying small molecules that modulate premature translation termination and nonsense mediated mRNA decay |
US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
WO2004101766A2 (fr) * | 2003-05-12 | 2004-11-25 | The Children's Hospital Of Philadelphia | Compositions a base de grp94 et procedes d'utilisation associes |
DE60325107D1 (de) * | 2003-08-25 | 2009-01-15 | Marc Ramael | Verfahren und kit zum quantitativen und/oder qualitativen nachweis von komponenten in einer probe |
EP2816351A3 (fr) * | 2004-01-27 | 2015-03-25 | Compugen Ltd. | Procédés et systèmes d'annotation de séquences biomoléculaires |
WO2005093413A2 (fr) * | 2004-03-22 | 2005-10-06 | Yale University | Diagnostic et traitement de la preeclampsie |
WO2006071247A2 (fr) * | 2004-03-30 | 2006-07-06 | California Institute Of Technology | Analyses diagnostiques comprenant des analyses immunologiques sur membrane multiplexees faisant intervenir des points quantiques |
CN101437959A (zh) * | 2004-09-20 | 2009-05-20 | 普罗特奥格尼克斯公司 | 诊断胎儿非整倍体 |
WO2006099126A2 (fr) * | 2005-03-11 | 2006-09-21 | Ciphergen Biosystems, Inc. | Biomarqueurs du cancer de l'ovaire et de l'endometre: la hepcidine |
US7604948B2 (en) * | 2005-05-05 | 2009-10-20 | The Regents Of The University Of California | Biomarkers for diagnosing an autism spectrum disorder |
US7575876B2 (en) * | 2005-10-27 | 2009-08-18 | The University Of Washington | Biomarkers for neurodegenerative disorders |
-
2005
- 2005-07-14 EP EP10003541.9A patent/EP2199801B1/fr not_active Not-in-force
- 2005-07-14 DE DE602005023629T patent/DE602005023629D1/de active Active
- 2005-07-14 EP EP14183123.0A patent/EP2848942B1/fr not_active Not-in-force
- 2005-07-14 WO PCT/US2005/024985 patent/WO2006019906A1/fr active Application Filing
- 2005-07-14 EP EP10009544.7A patent/EP2261672B1/fr not_active Not-in-force
- 2005-07-14 EP EP17158112.7A patent/EP3203241A1/fr not_active Withdrawn
- 2005-07-14 AT AT05771584T patent/ATE481645T1/de not_active IP Right Cessation
- 2005-07-14 DK DK10003541.9T patent/DK2199801T3/da active
- 2005-07-14 EP EP05771584A patent/EP1789805B1/fr not_active Not-in-force
-
2009
- 2009-12-03 US US12/630,458 patent/US8323915B2/en not_active Expired - Fee Related
-
2012
- 2012-11-28 US US13/688,077 patent/US9110083B2/en not_active Expired - Fee Related
-
2015
- 2015-08-17 US US14/828,397 patent/US20160069886A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027216A1 (en) * | 2001-07-02 | 2003-02-06 | Kiernan Urban A. | Analysis of proteins from biological fluids using mass spectrometric immunoassay |
WO2004012588A2 (fr) * | 2002-08-06 | 2004-02-12 | The Johns Hopkins University | Utilisation de biomarqueurs dans la detection du cancer de l'ovaire |
Non-Patent Citations (3)
Title |
---|
KOZAK K R ET AL: "CHARACTERIZATION OF SERUM BIOMAKERS FOR DETECTION OF EARLY STAGE OVARIAN CANCER", PROTEOMICS, WILEY - VCH VERLAG, WEINHEIM, DE LNKD- DOI:10.1002/PMIC.200500093, vol. 5, no. 17, 1 November 2005 (2005-11-01), pages 4589 - 4596, XP008056606, ISSN: 1615-9853 * |
TOSNER J ET AL: "SERUM PREALBUMIN, TRANSFERIN AND ALPHA-1-ACID GLYCOPROTEIN IN PATIENTS WITH GYNECOLOGICAL CARCINOMAS", NEOPLASMA, SCIENCES, vol. 35, no. 4, 1 January 1988 (1988-01-01), pages 403 - 412, XP008056610, ISSN: 0028-2685 * |
ZHANG ZHEN ET AL: "Protein identification and immunoassay evaluation of a panel of biomarkers discovered through proteomic profiling for the detection of ovarian cancer", PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 45, 1 March 2004 (2004-03-01), pages 242, XP002485511, ISSN: 0197-016X * |
Also Published As
Publication number | Publication date |
---|---|
EP1789805B1 (fr) | 2010-09-15 |
WO2006019906A1 (fr) | 2006-02-23 |
US20100081151A1 (en) | 2010-04-01 |
EP2261672A3 (fr) | 2011-10-05 |
EP2848942B1 (fr) | 2017-03-08 |
EP3203241A1 (fr) | 2017-08-09 |
US20130090256A1 (en) | 2013-04-11 |
DE602005023629D1 (de) | 2010-10-28 |
EP2848942A1 (fr) | 2015-03-18 |
EP2199801A2 (fr) | 2010-06-23 |
EP2261672A2 (fr) | 2010-12-15 |
EP2199801B1 (fr) | 2013-05-29 |
ATE481645T1 (de) | 2010-10-15 |
US20160069886A1 (en) | 2016-03-10 |
US9110083B2 (en) | 2015-08-18 |
EP1789805A1 (fr) | 2007-05-30 |
US8323915B2 (en) | 2012-12-04 |
DK2199801T3 (da) | 2013-08-05 |
EP2261672B1 (fr) | 2014-09-03 |
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