EP2197827B1 - Method of inhibiting polymerization and fouling in acrylic acid and acrylate processes - Google Patents
Method of inhibiting polymerization and fouling in acrylic acid and acrylate processes Download PDFInfo
- Publication number
- EP2197827B1 EP2197827B1 EP08782493.4A EP08782493A EP2197827B1 EP 2197827 B1 EP2197827 B1 EP 2197827B1 EP 08782493 A EP08782493 A EP 08782493A EP 2197827 B1 EP2197827 B1 EP 2197827B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- inhibitor
- acrylic acid
- ppm
- tower
- oxyl compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 title claims description 60
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 title claims description 55
- 238000000034 method Methods 0.000 title claims description 33
- 238000006116 polymerization reaction Methods 0.000 title claims description 24
- 230000002401 inhibitory effect Effects 0.000 title claims description 5
- 230000008569 process Effects 0.000 title description 19
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 title description 5
- 239000003112 inhibitor Substances 0.000 claims description 73
- UZFMOKQJFYMBGY-UHFFFAOYSA-N 4-hydroxy-TEMPO Chemical compound CC1(C)CC(O)CC(C)(C)N1[O] UZFMOKQJFYMBGY-UHFFFAOYSA-N 0.000 claims description 58
- WAEMQWOKJMHJLA-UHFFFAOYSA-N Manganese(2+) Chemical compound [Mn+2] WAEMQWOKJMHJLA-UHFFFAOYSA-N 0.000 claims description 51
- 150000001875 compounds Chemical class 0.000 claims description 30
- 229910001437 manganese ion Inorganic materials 0.000 claims description 27
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 20
- 239000007864 aqueous solution Substances 0.000 claims description 17
- 229910052760 oxygen Inorganic materials 0.000 claims description 17
- 239000001301 oxygen Substances 0.000 claims description 17
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 16
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- 238000004821 distillation Methods 0.000 claims description 10
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 10
- 229920002554 vinyl polymer Polymers 0.000 claims description 10
- 238000010791 quenching Methods 0.000 claims description 9
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 claims description 8
- 229950000688 phenothiazine Drugs 0.000 claims description 8
- CYUZOYPRAQASLN-UHFFFAOYSA-N 3-prop-2-enoyloxypropanoic acid Chemical compound OC(=O)CCOC(=O)C=C CYUZOYPRAQASLN-UHFFFAOYSA-N 0.000 claims description 3
- 239000007789 gas Substances 0.000 claims description 3
- 230000000087 stabilizing effect Effects 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 2
- 239000007795 chemical reaction product Substances 0.000 claims 1
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- 239000007788 liquid Substances 0.000 description 14
- -1 i.e. Polymers 0.000 description 13
- 229920000642 polymer Polymers 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- 230000006698 induction Effects 0.000 description 12
- GDOPTJXRTPNYNR-UHFFFAOYSA-N methyl-cyclopentane Natural products CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 12
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- 150000002148 esters Chemical class 0.000 description 9
- 239000000178 monomer Substances 0.000 description 8
- 238000000746 purification Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 239000011572 manganese Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 239000000539 dimer Substances 0.000 description 6
- 125000001183 hydrocarbyl group Chemical group 0.000 description 5
- 150000002696 manganese Chemical class 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000006641 stabilisation Effects 0.000 description 5
- 238000011105 stabilization Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- RKMGAJGJIURJSJ-UHFFFAOYSA-N 2,2,6,6-tetramethylpiperidine Chemical compound CC1(C)CCCC(C)(C)N1 RKMGAJGJIURJSJ-UHFFFAOYSA-N 0.000 description 4
- 238000006845 Michael addition reaction Methods 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 125000004429 atom Chemical group 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 4
- UOGMEBQRZBEZQT-UHFFFAOYSA-L manganese(2+);diacetate Chemical compound [Mn+2].CC([O-])=O.CC([O-])=O UOGMEBQRZBEZQT-UHFFFAOYSA-L 0.000 description 4
- 235000020004 porter Nutrition 0.000 description 4
- 150000003254 radicals Chemical class 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical class [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 3
- 150000001412 amines Chemical class 0.000 description 3
- 239000006227 byproduct Substances 0.000 description 3
- 238000002425 crystallisation Methods 0.000 description 3
- 230000008025 crystallization Effects 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 229910052748 manganese Inorganic materials 0.000 description 3
- 229940071125 manganese acetate Drugs 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 239000012074 organic phase Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 239000011593 sulfur Substances 0.000 description 3
- 229910052717 sulfur Inorganic materials 0.000 description 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical class [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 125000003158 alcohol group Chemical group 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 150000001879 copper Chemical class 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 238000004817 gas chromatography Methods 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 239000011976 maleic acid Substances 0.000 description 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid group Chemical group C(\C=C/C(=O)O)(=O)O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 150000002832 nitroso derivatives Chemical class 0.000 description 2
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 239000011574 phosphorus Chemical class 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000002243 precursor Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- 150000003673 urethanes Chemical class 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 description 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 1
- BPIUIOXAFBGMNB-UHFFFAOYSA-N 1-hexoxyhexane Chemical compound CCCCCCOCCCCCC BPIUIOXAFBGMNB-UHFFFAOYSA-N 0.000 description 1
- ATVJXMYDOSMEPO-UHFFFAOYSA-N 3-prop-2-enoxyprop-1-ene Chemical compound C=CCOCC=C ATVJXMYDOSMEPO-UHFFFAOYSA-N 0.000 description 1
- UWDMKTDPDJCJOP-UHFFFAOYSA-N 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-ium-4-carboxylate Chemical compound CC1(C)CC(O)(C(O)=O)CC(C)(C)N1 UWDMKTDPDJCJOP-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical group SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- ISTIEXLDUGQAAO-UHFFFAOYSA-J [Mn+4].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O Chemical compound [Mn+4].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O ISTIEXLDUGQAAO-UHFFFAOYSA-J 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- YLFIGGHWWPSIEG-UHFFFAOYSA-N aminoxyl Chemical compound [O]N YLFIGGHWWPSIEG-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 125000003710 aryl alkyl group Chemical group 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 229940076286 cupric acetate Drugs 0.000 description 1
- 238000006114 decarboxylation reaction Methods 0.000 description 1
- 238000006471 dimerization reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- ZQRKKRPGMWJFCH-UHFFFAOYSA-N ethyl n-octadecylcarbamate Chemical compound CCCCCCCCCCCCCCCCCCNC(=O)OCC ZQRKKRPGMWJFCH-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 239000004611 light stabiliser Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- BHVPEUGTPDJECS-UHFFFAOYSA-L manganese(2+);diformate Chemical compound [Mn+2].[O-]C=O.[O-]C=O BHVPEUGTPDJECS-UHFFFAOYSA-L 0.000 description 1
- SGGOJYZMTYGPCH-UHFFFAOYSA-L manganese(2+);naphthalene-2-carboxylate Chemical compound [Mn+2].C1=CC=CC2=CC(C(=O)[O-])=CC=C21.C1=CC=CC2=CC(C(=O)[O-])=CC=C21 SGGOJYZMTYGPCH-UHFFFAOYSA-L 0.000 description 1
- SGLXWMAOOWXVAM-UHFFFAOYSA-L manganese(2+);octanoate Chemical compound [Mn+2].CCCCCCCC([O-])=O.CCCCCCCC([O-])=O SGLXWMAOOWXVAM-UHFFFAOYSA-L 0.000 description 1
- MMIPFLVOWGHZQD-UHFFFAOYSA-N manganese(3+) Chemical compound [Mn+3] MMIPFLVOWGHZQD-UHFFFAOYSA-N 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 125000005395 methacrylic acid group Chemical group 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- BHWVXPZCVBYKCR-UHFFFAOYSA-L n,n-diphenylcarbamodithioate;manganese(2+) Chemical compound [Mn+2].C=1C=CC=CC=1N(C(=S)[S-])C1=CC=CC=C1.C=1C=CC=CC=1N(C(=S)[S-])C1=CC=CC=C1 BHWVXPZCVBYKCR-UHFFFAOYSA-L 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- FVZVCSNXTFCBQU-UHFFFAOYSA-N phosphanyl Chemical group [PH2] FVZVCSNXTFCBQU-UHFFFAOYSA-N 0.000 description 1
- 125000005328 phosphinyl group Chemical group [PH2](=O)* 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000027756 respiratory electron transport chain Effects 0.000 description 1
- 238000002390 rotary evaporation Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 230000009044 synergistic interaction Effects 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- 229920006029 tetra-polymer Polymers 0.000 description 1
- 150000004685 tetrahydrates Chemical class 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
- C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
- C09K15/30—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing heterocyclic ring with at least one nitrogen atom as ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/50—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/62—Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/38—Polymerisation using regulators, e.g. chain terminating agents, e.g. telomerisation
- C08F2/40—Polymerisation using regulators, e.g. chain terminating agents, e.g. telomerisation using retarding agents
Definitions
- This invention relates to acrylic acid processes.
- the invention relates to inhibiting unwanted acrylic polymerization and the resulting fouling of process equipment while in another aspect, the invention relates to the use in the acrylic processes of an inhibitor comprising a N-oxyl compound and a manganese ion.
- the invention relates to an inhibitor comprising a high ratio of N-oxyl compound to manganese ion.
- the gaseous product stream is quenched with cold process liquids before it is subjected to purification.
- the quench produces a liquid stream of at least 25 weight percent (wt%) liquid acrylic acid, at most 75 wt% water, and minor amounts of various liquid by-products.
- the majority of the cold process liquids typically comprise aqueous acrylic acid taken from the base of the quench tower and pumped to the top of the tower. Since liquid acrylic acid is much more susceptible to unwanted vinyl polymerization than is gaseous acrylic acid, a polymerization inhibitor is typically added to the stream in this pump-around loop.
- hydroquinone either alone or in combination with a metal ion such as an ion of manganese or copper. While these inhibitors are effective, they can also result in the fouling of the process equipment, typically the purification equipment such as the steam generators, if the reaction water is recycled to the reactors.
- hydroquinone will react with formaldehyde, a by-product of the acrylic acid process, to form a novolak-type polymer that will attach to equipment sidewalls and valves. This polymeric foulant then interferes with the heat exchange across the equipment sidewalls and the operation of the valves. This, in turn, can require frequent cleaning and down-time of the equipment.
- This novolak-type polymer fouling can be eliminated by replacing the hydroquinone inhibitor with another water-soluble inhibitor that will not react with formaldehyde.
- USP 5,504,243 describes a method for inhibiting the polymerization of (meth)acrylic acid and esters using an inhibitor comprising an N-oxyl compound, e.g., 4-hydroxy TEMPO (4-HT), in combination with two or more of a manganese salt, copper salt, 2,2,6,6-tetramethylpiperidine and a nitroso compound.
- EP 0 685 447 describes a similar inhibitor, but this one comprising an N-oxyl compound in combination with one or more of a manganese salt, copper salt, 2,2,6,6-tetramethylpiperidine and a nitroso compound.
- the combination of 4-HT and a manganese salt provided only 4 hours of inhibition at 100°C when the 4-HT and manganese were present in a weight ratio between 1.33:1 to 1:1.
- only a very small amount of inhibitor was used (about 10 parts per million (ppm) of each component), and typically at least 100 ppm of total inhibitor is required in a commercial distillation tower for good distribution of the inhibitor over the tower trays.
- the invention is a method of inhibiting the vinyl polymerization of acrylic acid or methacrylic acid in an aqueous solution and in the presence of oxygen, the method comprising the step of mixing with the aqueous solution an inhibitor comprising (i) at least 50 ppm of an N-oxyl compound, and (ii) a manganese ion, the N-oxyl compound and manganese ion present in a N-oxyl compound to manganese ion weight ratio of 50:1 to less than 100:1 based on the the acrylic acid or methacrylic acid.
- the amount of air fed to the tower is such that oxygen comprises at least 0.1 mole percent (mol%) of the gas within the tower.
- the invention is an inhibitor for stabilizing an aqueous solution of acrylic acid or methacrylic acid against polymerization in the presence of oxygen, the inhibitor comprising an N-oxyl compound and a manganese ion at a weight ratio of 50:1 to less than 100:1.
- the invention may be used to provide a stabilized aqueous solution of acrylic acid or methacrylic acid the solution comprising (i) acrylic acid or methacrylic acid, (ii) water, and (iii) an inhibitor comprising an N-oxyl compound and a manganese ion at a weight ratio of 50:1 to less than 100:1 in the presence of oxygen.
- Polymer means a polymeric compound prepared by polymerizing monomers, whether of the same or a different type.
- the generic term polymer thus embraces the term homopolymer, usually employed to refer to polymers prepared from only one type of monomer, and the terms copolymer and interpolymer as defined below.
- Copolymer and interpolymer means a polymer prepared by the polymerization of at least two different types of monomers. These generic terms include the traditional definition of copolymers, i.e., polymers prepared from two different types of monomers, and the more expansive definition of copolymers, i.e., polymers prepared from more than two different types of monomers, e.g., terpolymers, tetrapolymers.
- (meth) with generic terms, such as, for example, "acrylic acid” or “acrylate” broadens the base or root terms to include both acrylic and methacrylic, and acrylate and methacrylate species.
- (meth)acrylic acid includes acrylic acid and methacrylic acid
- (meth)acrylate includes acrylate and methacrylate species.
- Polymerization means a chemical reaction in which a large number of relatively simple molecules combine to form a chain-like macromolecule, i.e., a polymer.
- the combining units are known as monomers.
- Inhibitor means a substance that will prevent or retard the polymerization of vinyl monomers under conditions of which the monomers would otherwise polymerize.
- the Michael addition of one acrylic acid or ester molecule to another is not a polymerization of acrylic acid or ester molecules.
- solution means a uniformly dispersed mixture at the molecular or ionic level of one or more substances (the solute) in one or more other substances (the solvent).
- the acrylic acid is the solute and water is the solvent, and the water can be present in amounts up to and exceeding 75 weight percent based on the weight of the solution.
- solution also includes aqueous compositions in which water is present in only trace amounts, e.g., less than 0.01 weight percent based on the weight of the solution.
- the family of free radical polymerization inhibitors used in the practice of this invention is based on 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl also known as nitroxyl 2, or NR 1, or 4-oxypiperidol, or tanol, or tempol, or tmpn, or probably most commonly, 4-hydroxy-TEMPO, or h-TEMPO or even more simply, 4-HT.
- These TEMPO compounds are also known as N-oxyl or, more simply, oxyl compounds or stabilizers, or HARTs (hindered amine radical traps), or HALS (hindered amine light stabilizers).
- the TEMPO family members are differentiated by various groups located at the 4 position of the ring.
- the most commonly known member of the family is 4-hydroxy TEMPO (4-HT), a preferred N-oxy compound for use in this invention, in which a hydroxyl group is located at the 4 position of the ring (see formula (I)):
- TEMPO compounds from which a derivative, particularly the ether, ester and urethane derivates, can be prepared are of formula (II):
- the ether, ester and urethane derivatives of a TEMPO compound that can be used as a component of the polymerization inhibitors in the practice of this invention have the chemical structural formula of (III): in which X of formula II is any group that can react with another compound, e.g., an alcohol, a carboxylic acid, an alkyl sulfate, an isocyanate, etc., to form the ether, ester or urethane group (or corresponding sulfur, phosphorus or amine derivative) of formula III, and preferably X is hydroxyl, amine, mercaptan, phosphino (H 2 P-), phosphinyl (H 2 P(O)-) or silyl (H 3 Si-) group, and more preferably X is hydroxyl; X' of formula III is at least a divalent atom, preferably an atom of oxygen, sulfur, nitrogen, phosphorus or silicon, more preferably an atom of oxygen or sulfur and most preferably an atom
- ether, ester and urethane derivatives are the compounds of formula III in which X' is a divalent oxygen radical.
- the hydrocarbyl groups of R 1 -R 7 include alkyl, aryl, aralkyl, cycloalky and alkenyl.
- R 1 -R 4 are each independently a C 1-4 alkyl group and more preferably, R 1 -R 4 are each independently methyl groups.
- R 6 is a C 1-12 alkyl, or a C 1-12 alkyl carboxyl or an aryl carboxyl group, or a urethane group, and more preferably a C 1-8 alkyl group, or benzoic acid group, or a urethane group.
- R 7 is a C 5-30 alkyl group, more preferably a C 5-20 alkyl group.
- Representative ether and urethane derivatives of 4-hydroxy-TEMPO include methyl ether TEMPO, butyl ether TEMPO, hexyl ether TEMPO, allyl ether TEMPO and stearyl urethane TEMPO.
- 4-HT and Mn(II) are added to streams containing acrylic acid.
- the 4-HT reacts with acrylic acid forming either the 4-HT acrylate ester (V below, i.e., the ester formed from the alcohol function of 4-HT with the carboxylic acid function of acrylic acid) or the Michael adduct Beta-(4-oxy TEMPO) propionic acid (VI below, i.e., the Michael adduct formed when the alcohol function of 4-HT adds across the double bond of the acrylic acid).
- V 4-HT acrylate ester
- V the Michael adduct Beta-(4-oxy TEMPO) propionic acid
- VI i.e., the Michael adduct formed when the alcohol function of 4-HT adds across the double bond of the acrylic acid.
- the 4-HT can react to a lesser extent (due to the lower concentration of these species being present in the mixture) with acetic acid forming the 4-HT acetate ester (VII below) and with the acrylic acid dimer forming the corresponding ester (VIII below) and Michael adducts (IX below).
- acetic acid forming the 4-HT acetate ester (VII below)
- acrylic acid dimer forming the corresponding ester (VIII below) and Michael adducts (IX below).
- the true inhibitor system in acrylic acid distillation is these 4-HT derivatives in conjunction with the Mn(II) ion.
- gas chromatography (GC) and high pressure liquid chromotography (HPLC) analysis of the distillation streams will not show the presence of 4-HT, these and other potential derivatives can be found.
- the inhibitor package i.e., the active nitroxyl derivative in conjunction with manganese ion
- the inhibitor package can be formed either in situ by the direct addition of 4-HT and manganese ion to the process, or it can be preformed by external reaction with acrylic acid and then added to the process along with manganese ion.
- the manganese ion used in the practice of this invention is preferably of a +2 valence, and it is typically derived from a manganese salt such as, for example, manganese dialkyldithiocarbamate (the alkyl groups are selected from methyl, ethyl, propyl and butyl and may be same or different with each other), manganese diphenyldithiocarbamate, manganese formate, manganese acetate, manganese octanate, manganese naphthenate and manganese ethylenediaminetetraacetate. One or more kinds of them may be used.
- a manganese salt such as, for example, manganese dialkyldithiocarbamate (the alkyl groups are selected from methyl, ethyl, propyl and butyl and may be same or different with each other), manganese diphenyldithiocarbamate, manganese formate, manganese acetate,
- the N-oxyl compound to manganese ion weight ratio is 50:1 to less than 100:1, preferably to less than 75:1 and more preferably to less than 60:1, based on the aqueous solution of (meth)acrylic acid and water. At these ratios and with a minimum of at least 50 ppm 4-HT, a super stabilizing effect is imparted to an aqueous solution of (meth)acrylic acid, i.e., the majority (e.g., >50%) of the (meth)acrylic acid will dimerize via Michael addition before vinyl polymerization can occur.
- the components of the inhibitor i.e., the N-oxyl compound and the manganese ion precursor (e.g., a salt), can either be pre-mixed or added independently to the aqueous solution of (meth)acrylic acid.
- the inhibitor (N-oxyl compound plus manganese ion precursor) are added either to the water used to make the aqueous solution of (meth)acrylic acid, or to the solution itself, in amount of at least 50, preferably at least 100 and more preferably at least 200, ppm.
- the inhibitor is usually added at the quench stage of the process.
- the inhibitor is pre-mixed, then it is typically added to the cold process liquids before or at the time that these liquids enter the top of the tower in which the gaseous (meth)acrylic acid is quenched.
- the temperature of these process liquids is typically between 15 and 30°C. If the components of the inhibitor are added to the process independent of one another, then they are typically added to the quench liquids before the liquids enter the quench tower, and additional amounts of the components can be added to different sections of the quench tower to insure a synergistic interaction of components throughout the purification process.
- An inhibitor solution is easily prepared by adding manganese acetate solids or solution to a commercially available ten percent aqueous solution of 4-hydroxy-TEMPO. In a preferred embodiment, this solution is then fed directly to the pump-around loop of the absorber (quench) tower or fed to a distillation tower by way of the reflux, i.e., that part of the condensed overhead vapor which is returned to the top tray.
- the inhibitor solution can also be added to a tower condenser, e.g., a quench condenser, and/or to a simple flasher, i.e., a one-stage distillation unit.
- the inhibitor of N-oxyl compound and manganese ion is used in combination with an inhibitor that is soluble in an organic medium.
- the N-oxyl compound, particularly 4-hydorxy TEMPO, and the manganese salt are both very water-soluble and as such, only partially partition into the organic phase within the extraction and/or distillation towers. This, in turn, only provides partial stabilization against vinyl polymerization of acrylic acid or methacrylic acid that is contained with the organic phase.
- the inhibitor can comprise one or more additional components that provides this function, e.g., phenothiazine. This additional component or blend of components, if present, is usually present in an amount of 50, preferably 100 and more preferably 200, ppm.
- 4-Hydroxy-TEMPO by itself is stoichiometrically consumed as an inhibitor, and it does not require the presence of oxygen to function as an inhibitor.
- the presence of Mn(II) and oxygen allows for the regeneration of those 4-hydroxy-TEMPOs that have trapped a radical, thus making it a catalytic inhibitor.
- the oxygen is provided to the towers by air injection into either the reboiler or base of the tower.
- the Mn(II) serves two purposes. One purpose is to act as an oxidation catalyst for regeneration of 4-hydroxy-TEMPOs that have trapped a radical. Another purpose is when oxidized to Mn(III), it can act as an inhibitor via one electron transfer from a carbon centered radical forming a carbo-cation and Mn(II), and thus preventing polymerization.
- 4-HT in conjunction with Mn(II) can provide super stabilization of acrylic acid at 113°C.
- the preferred inhibitor ratios for acrylic acid distillation of this synergistic inhibitor mix is 100/1 (4-HT/Mn(II)) with a more preferred ratio of 50/1.
- the inhibitor concentration on each tray should be at least 50 ppm 4-HT/1 ppm Mn(II), the more preferred level is at least 100 ppm 4-HT/2 ppm Mn(II) and an even more preferred concentration is at least 200 ppm 4-HT/4 ppm Mn(II).
- At lower levels inhibitor distribution on the trays can be a concern and lead to fouling due to poor distribution in commercial scale equipment.
- 4-HT in acrylic acid purification is its ability to catalyze the decomposition of maleic acid in a finishing column base section and/or reboiler and even more effectively, in a dimer cracker.
- the 4-HT acts as a catalyst for the decomposition of maleic acid via decarboxylation yielding acrylic acid.
- the high temperature (typically above 150°C) of the dimer cracker is preferred for this reaction although this reaction proceeds well at temperatures as low as 120°C.
- This characteristic of 4-HT is not observed with other non-TEMPO acrylic acid inhibitors, e.g., PTZ or HQ. This means that 4-HT not only prevents fouling in the purification system but also converts a reactor by-product into product in the purification system thus maximizing yields.
- the typical concentration of 4-HT in either the finishing column reboiler or dimer cracker is at least 500, preferably at least 1,000 and more preferably at least 2,000, ppm. Because 4-HT is a high boiler, it tends to concentrate in the reboiler of a finishing tower which can be equipped with a dimer cracker.
- the typical temperature for cracking the dimer in the presence of 4-HT is at least 150, preferably at least 170 and more preferably at least 200, °C.
- DOT tubes are 10 mL glass ampoules equipped with a 150 mm (6 inch) long, 6 mm (1 ⁇ 4 inch) diameter glass tubing neck, which are fitted with 6 mm (1 ⁇ 4 inch) Swagelok tm nylon caps. The caps are used to support the tubes which extend through twelve 10 mm (3/8 inch) holes in a 150 mm (6 inch) diameter circular plastic block that is about 25 mm (one inch) thick. The block is attached by an offset center support rod to an overhead stirrer.
- the bulb portion of the tubes are then submerged in a constant temperature silicon oil bath held at 113°C for 72 hours while being rotated ( via the overhead stirrer) at about 50 rpm.
- the tubes are visually monitored during this time for signs of polymer formation (i.e. cloudiness, presence of solids or increased viscosity).
- the amount of time until first signs of polymer formation is defined as the induction time (or on-set time).
- Each run consists of six replicate DOT tubes, and the induction time is the average of these six replicates.
- the pressure tubes are sealed with pressure heads which are equipped with a pressure gauge. After securing the heads, the tubes are submerged (covering only the liquid level of the tubes) in a constant temperature oil bath at 149°C for 4 hrs with an autogenic pressure of 170 kPa (25 psig). The tubes are visually monitored during this time for the presence of polymer.
- a one liter, round-bottom flask is charged with about 400 mL of Aldrich glacial acrylic acid (inhibited with 200 ppm MeHQ).
- the flask is attached to a rotary evaporator equipped with a 50°C water bath and vacuum pulled (about 20 mm Hg absolute pressure).
- About 250 mL of distilled acrylic acid is collected in the ice-water cooled receiver. This is melted and then subjected to rotary evaporation again to produce material that contains less than 1 ppm MeHQ and is used for the rest of the induction time studies.
- 4-HT is tested to determine its efficacy as a polymerization inhibitor for acrylic acid. Potential adverse inhibition interactions of 4-HT with the other inhibitors are also evaluated.
- the results from the standard lab induction time tests are contained in Table I. All tests are run at 113°C, the maximum reboiler wall temperature expected in a solvent removal tower. Also all tests are conducted under an air headspace.
- An inhibitor package consisting of 50 ppm 4-HT and 1 ppm of Mn(II) in the presence of oxygen provides super stabilization, i.e., the acrylic acid contains sufficient inhibitor to allow most of the acrylic acid to undergo dimerization before vinyl polymerization occurs.
- the induction time exceeds the amount of time it take for >90% of the acrylic acid to undergo Michael additions (which means that after 72 hours at 113°C very little free acrylic acid is still present).
- the acrylic acid dimer can also polymerize to give a clear glassy solid if heating is continued for an extended period.
- the Fischer & Porter pressure tube test is a simulation of conditions expected in steam generators. After fours hours at 149°C the synthetic reaction water (85% water / 10% acetic acid / 5% acrylic acid) shows no signs of vinyl polymerization for either the 4-HT/Mn(II) or HQ/Mn(II) inhibited solutions. This means that both inhibitor packages provide vinyl polymerization protection for times significantly greater than commercial steam generator residence times.
- the inhibitor concentration employed (1000 ppm HQ / 10 ppm Mn +2 and 500 ppm 4-HT / 10 ppm Mn +2 ) are those expected (based on unit mass balance) if a 100 ppm HQ / 1 ppm Mn (II) inhibitor package is replaced with a 50 ppm 4-HT / 1 ppm Mn (II) inhibitor package.
- This test simulates a steam generator residue and reflects the fact that the inhibitors would be concentrated in this stream.
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Description
- This invention relates to acrylic acid processes. In one aspect, the invention relates to inhibiting unwanted acrylic polymerization and the resulting fouling of process equipment while in another aspect, the invention relates to the use in the acrylic processes of an inhibitor comprising a N-oxyl compound and a manganese ion. In still another aspect, the invention relates to an inhibitor comprising a high ratio of N-oxyl compound to manganese ion.
- In the vapor phase manufacture of acrylic acid from propylene and air, the gaseous product stream is quenched with cold process liquids before it is subjected to purification. The quench produces a liquid stream of at least 25 weight percent (wt%) liquid acrylic acid, at most 75 wt% water, and minor amounts of various liquid by-products. The majority of the cold process liquids typically comprise aqueous acrylic acid taken from the base of the quench tower and pumped to the top of the tower. Since liquid acrylic acid is much more susceptible to unwanted vinyl polymerization than is gaseous acrylic acid, a polymerization inhibitor is typically added to the stream in this pump-around loop.
- One family of commonly used inhibitors comprises hydroquinone either alone or in combination with a metal ion such as an ion of manganese or copper. While these inhibitors are effective, they can also result in the fouling of the process equipment, typically the purification equipment such as the steam generators, if the reaction water is recycled to the reactors. For example, hydroquinone will react with formaldehyde, a by-product of the acrylic acid process, to form a novolak-type polymer that will attach to equipment sidewalls and valves. This polymeric foulant then interferes with the heat exchange across the equipment sidewalls and the operation of the valves. This, in turn, can require frequent cleaning and down-time of the equipment.
- This novolak-type polymer fouling can be eliminated by replacing the hydroquinone inhibitor with another water-soluble inhibitor that will not react with formaldehyde. For example,
USP 5,504,243 describes a method for inhibiting the polymerization of (meth)acrylic acid and esters using an inhibitor comprising an N-oxyl compound, e.g., 4-hydroxy TEMPO (4-HT), in combination with two or more of a manganese salt, copper salt, 2,2,6,6-tetramethylpiperidine and a nitroso compound. The European equivalent of this patent, i.e.,EP 0 685 447 , describes a similar inhibitor, but this one comprising an N-oxyl compound in combination with one or more of a manganese salt, copper salt, 2,2,6,6-tetramethylpiperidine and a nitroso compound. However, in this equivalent the combination of 4-HT and a manganese salt provided only 4 hours of inhibition at 100°C when the 4-HT and manganese were present in a weight ratio between 1.33:1 to 1:1. Moreover, only a very small amount of inhibitor was used (about 10 parts per million (ppm) of each component), and typically at least 100 ppm of total inhibitor is required in a commercial distillation tower for good distribution of the inhibitor over the tower trays. Still further, the relatively large amount of manganese ion (metal) becomes an unwanted contributor to the ash from the incinerators in which the process waste stream (the ultimate repository for the inhibitor) is disposed. Yet further, this reference is void of any teaching that oxygen is an essential component of the inhibitor package. - In one embodiment, the invention is a method of inhibiting the vinyl polymerization of acrylic acid or methacrylic acid in an aqueous solution and in the presence of oxygen, the method comprising the step of mixing with the aqueous solution an inhibitor comprising (i) at least 50 ppm of an N-oxyl compound, and (ii) a manganese ion, the N-oxyl compound and manganese ion present in a N-oxyl compound to manganese ion weight ratio of 50:1 to less than 100:1 based on the the acrylic acid or methacrylic acid. The amount of air fed to the tower is such that oxygen comprises at least 0.1 mole percent (mol%) of the gas within the tower.
- In another embodiment, the invention is an inhibitor for stabilizing an aqueous solution of acrylic acid or methacrylic acid against polymerization in the presence of oxygen, the inhibitor comprising an N-oxyl compound and a manganese ion at a weight ratio of 50:1 to less than 100:1.
- The invention may be used to provide a stabilized aqueous solution of acrylic acid or methacrylic acid the solution comprising (i) acrylic acid or methacrylic acid, (ii) water, and (iii) an inhibitor comprising an N-oxyl compound and a manganese ion at a weight ratio of 50:1 to less than 100:1 in the presence of oxygen.
- "Polymer" means a polymeric compound prepared by polymerizing monomers, whether of the same or a different type. The generic term polymer thus embraces the term homopolymer, usually employed to refer to polymers prepared from only one type of monomer, and the terms copolymer and interpolymer as defined below.
- "Copolymer" and "interpolymer" means a polymer prepared by the polymerization of at least two different types of monomers. These generic terms include the traditional definition of copolymers, i.e., polymers prepared from two different types of monomers, and the more expansive definition of copolymers, i.e., polymers prepared from more than two different types of monomers, e.g., terpolymers, tetrapolymers.
- The prefix "(meth)" with generic terms, such as, for example, "acrylic acid" or "acrylate" broadens the base or root terms to include both acrylic and methacrylic, and acrylate and methacrylate species. Thus, the term "(meth)acrylic acid" includes acrylic acid and methacrylic acid, and the term "(meth)acrylate" includes acrylate and methacrylate species.
- "Polymerization" means a chemical reaction in which a large number of relatively simple molecules combine to form a chain-like macromolecule, i.e., a polymer. The combining units are known as monomers.
- "Inhibitor", "polymerization inhibitor", "stabilizer" and "polymerization stabilizer" means a substance that will prevent or retard the polymerization of vinyl monomers under conditions of which the monomers would otherwise polymerize. The Michael addition of one acrylic acid or ester molecule to another is not a polymerization of acrylic acid or ester molecules.
- "solution" means a uniformly dispersed mixture at the molecular or ionic level of one or more substances (the solute) in one or more other substances (the solvent). In the context of an aqueous solution of acrylic acid, the acrylic acid is the solute and water is the solvent, and the water can be present in amounts up to and exceeding 75 weight percent based on the weight of the solution. As used in this disclosure, solution also includes aqueous compositions in which water is present in only trace amounts, e.g., less than 0.01 weight percent based on the weight of the solution.
- The family of free radical polymerization inhibitors used in the practice of this invention is based on 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl also known as nitroxyl 2, or NR 1, or 4-oxypiperidol, or tanol, or tempol, or tmpn, or probably most commonly, 4-hydroxy-TEMPO, or h-TEMPO or even more simply, 4-HT. These TEMPO compounds are also known as N-oxyl or, more simply, oxyl compounds or stabilizers, or HARTs (hindered amine radical traps), or HALS (hindered amine light stabilizers). The TEMPO family members are differentiated by various groups located at the 4 position of the ring. The most commonly known member of the family is 4-hydroxy TEMPO (4-HT), a preferred N-oxy compound for use in this invention, in which a hydroxyl group is located at the 4 position of the ring (see formula (I)):
-
- The ether, ester and urethane derivatives of a TEMPO compound that can be used as a component of the polymerization inhibitors in the practice of this invention have the chemical structural formula of (III):
X of formula II is any group that can react with another compound, e.g., an alcohol, a carboxylic acid, an alkyl sulfate, an isocyanate, etc., to form the ether, ester or urethane group (or corresponding sulfur, phosphorus or amine derivative) of formula III, and preferably X is hydroxyl, amine, mercaptan, phosphino (H2P-), phosphinyl (H2P(O)-) or silyl (H3Si-) group, and more preferably X is hydroxyl;
X' of formula III is at least a divalent atom, preferably an atom of oxygen, sulfur, nitrogen, phosphorus or silicon, more preferably an atom of oxygen or sulfur and most preferably an atom of oxygen;
and with respect to both formulae II and III
R1-R4 are each independently a C1-12 hydrocarbyl group, or any of the R1-R4 groups can join with one or more of the other R1-R4 groups to form one or more hydrocarbyl rings, preferably with at least a 5 carbon atoms;
R5 is an oxyl (O•) radical;
R6 is a hydrogen or C1-12 hydrocarbyl or carboxyl group, or a urethane group of the formula
R7 is a C2-30 hydrocarbyl group. - As here used, "ether, ester and urethane derivatives" are the compounds of formula III in which X' is a divalent oxygen radical. The hydrocarbyl groups of R1-R7 include alkyl, aryl, aralkyl, cycloalky and alkenyl. Preferably, R1-R4 are each independently a C1-4 alkyl group and more preferably, R1-R4 are each independently methyl groups. Preferably R6 is a C1-12 alkyl, or a C1-12 alkyl carboxyl or an aryl carboxyl group, or a urethane group, and more preferably a C1-8 alkyl group, or benzoic acid group, or a urethane group. Preferably R7 is a C5-30 alkyl group, more preferably a C5-20 alkyl group. Representative ether and urethane derivatives of 4-hydroxy-TEMPO include methyl ether TEMPO, butyl ether TEMPO, hexyl ether TEMPO, allyl ether TEMPO and stearyl urethane TEMPO.
- As practiced in this invention, 4-HT and Mn(II) are added to streams containing acrylic acid. Under the conditions of a distillation system, the 4-HT reacts with acrylic acid forming either the 4-HT acrylate ester (V below, i.e., the ester formed from the alcohol function of 4-HT with the carboxylic acid function of acrylic acid) or the Michael adduct Beta-(4-oxy TEMPO) propionic acid (VI below, i.e., the Michael adduct formed when the alcohol function of 4-HT adds across the double bond of the acrylic acid). These are the two major products which are formed, and in each case the derivatives still have the active nitroxyl radical present. This means they are still potent inhibitors.
- Furthermore, the 4-HT can react to a lesser extent (due to the lower concentration of these species being present in the mixture) with acetic acid forming the 4-HT acetate ester (VII below) and with the acrylic acid dimer forming the corresponding ester (VIII below) and Michael adducts (IX below). Thus for all practical purposes, the true inhibitor system in acrylic acid distillation is these 4-HT derivatives in conjunction with the Mn(II) ion. Although gas chromatography (GC) and high pressure liquid chromotography (HPLC) analysis of the distillation streams will not show the presence of 4-HT, these and other potential derivatives can be found. This means that the inhibitor package (i.e., the active nitroxyl derivative in conjunction with manganese ion) can be formed either in situ by the direct addition of 4-HT and manganese ion to the process, or it can be preformed by external reaction with acrylic acid and then added to the process along with manganese ion.
- The manganese ion used in the practice of this invention is preferably of a +2 valence, and it is typically derived from a manganese salt such as, for example, manganese dialkyldithiocarbamate (the alkyl groups are selected from methyl, ethyl, propyl and butyl and may be same or different with each other), manganese diphenyldithiocarbamate, manganese formate, manganese acetate, manganese octanate, manganese naphthenate and manganese ethylenediaminetetraacetate. One or more kinds of them may be used.
- The N-oxyl compound to manganese ion weight ratio is 50:1 to less than 100:1, preferably to less than 75:1 and more preferably to less than 60:1, based on the aqueous solution of (meth)acrylic acid and water. At these ratios and with a minimum of at least 50 ppm 4-HT, a super stabilizing effect is imparted to an aqueous solution of (meth)acrylic acid, i.e., the majority (e.g., >50%) of the (meth)acrylic acid will dimerize via Michael addition before vinyl polymerization can occur. If liquid acrylic acid is held at an elevated temperature (e.g., 113°C for 72 hours), most of the acrylic acid is converted to a dimer and very little (e.g., <10%) free acrylic acid remains. Neither N-oxyl compound nor manganese ion alone produces this result, and the use of more manganese ion, e.g., the N-oxyl compound to manganese ion ratio of 1:1 taught in the art, adds to metal content of the waste streams that are ultimately incinerated. The incineration produces an ash with a metal content which requires disposal in an environmentally, and usually costly, manger.
- The components of the inhibitor, i.e., the N-oxyl compound and the manganese ion precursor (e.g., a salt), can either be pre-mixed or added independently to the aqueous solution of (meth)acrylic acid. The inhibitor (N-oxyl compound plus manganese ion precursor) are added either to the water used to make the aqueous solution of (meth)acrylic acid, or to the solution itself, in amount of at least 50, preferably at least 100 and more preferably at least 200, ppm. In the context of a gas-phase process for the manufacture of (meth)acrylic acid, the inhibitor is usually added at the quench stage of the process. If the inhibitor is pre-mixed, then it is typically added to the cold process liquids before or at the time that these liquids enter the top of the tower in which the gaseous (meth)acrylic acid is quenched. The temperature of these process liquids is typically between 15 and 30°C. If the components of the inhibitor are added to the process independent of one another, then they are typically added to the quench liquids before the liquids enter the quench tower, and additional amounts of the components can be added to different sections of the quench tower to insure a synergistic interaction of components throughout the purification process.
- An inhibitor solution is easily prepared by adding manganese acetate solids or solution to a commercially available ten percent aqueous solution of 4-hydroxy-TEMPO. In a preferred embodiment, this solution is then fed directly to the pump-around loop of the absorber (quench) tower or fed to a distillation tower by way of the reflux, i.e., that part of the condensed overhead vapor which is returned to the top tray. The inhibitor solution can also be added to a tower condenser, e.g., a quench condenser, and/or to a simple flasher, i.e., a one-stage distillation unit.
- In one embodiment of this invention, the inhibitor of N-oxyl compound and manganese ion is used in combination with an inhibitor that is soluble in an organic medium. The N-oxyl compound, particularly 4-hydorxy TEMPO, and the manganese salt are both very water-soluble and as such, only partially partition into the organic phase within the extraction and/or distillation towers. This, in turn, only provides partial stabilization against vinyl polymerization of acrylic acid or methacrylic acid that is contained with the organic phase. To protect against vinyl polymerization in the organic phase, the inhibitor can comprise one or more additional components that provides this function, e.g., phenothiazine. This additional component or blend of components, if present, is usually present in an amount of 50, preferably 100 and more preferably 200, ppm.
- 4-Hydroxy-TEMPO by itself is stoichiometrically consumed as an inhibitor, and it does not require the presence of oxygen to function as an inhibitor. The presence of Mn(II) and oxygen allows for the regeneration of those 4-hydroxy-TEMPOs that have trapped a radical, thus making it a catalytic inhibitor. The oxygen is provided to the towers by air injection into either the reboiler or base of the tower. The Mn(II) serves two purposes. One purpose is to act as an oxidation catalyst for regeneration of 4-hydroxy-TEMPOs that have trapped a radical. Another purpose is when oxidized to Mn(III), it can act as an inhibitor via one electron transfer from a carbon centered radical forming a carbo-cation and Mn(II), and thus preventing polymerization.
- At the proper levels and ratios, 4-HT in conjunction with Mn(II) can provide super stabilization of acrylic acid at 113°C. The preferred inhibitor ratios for acrylic acid distillation of this synergistic inhibitor mix is 100/1 (4-HT/Mn(II)) with a more preferred ratio of 50/1. In a distillation tower the inhibitor concentration on each tray should be at least 50 ppm 4-HT/1 ppm Mn(II), the more preferred level is at least 100 ppm 4-HT/2 ppm Mn(II) and an even more preferred concentration is at least 200 ppm 4-HT/4 ppm Mn(II). At lower levels inhibitor distribution on the trays can be a concern and lead to fouling due to poor distribution in commercial scale equipment. Higher ratios of Mn(II) in the inhibitor mix will provide inhibition but lead to disposal issues. In other words at a 1/1 ratio [4-HT/Mn(II)] and a minimum of 50 ppm 4-HT, the amount of ash generated in an incinerator used to dispose of process heavy ends would present an environmental problem. This is not an issue at the 50/1 ratio.
- One surprising advantage of 4-HT in acrylic acid purification is its ability to catalyze the decomposition of maleic acid in a finishing column base section and/or reboiler and even more effectively, in a dimer cracker. The 4-HT acts as a catalyst for the decomposition of maleic acid via decarboxylation yielding acrylic acid. The high temperature (typically above 150°C) of the dimer cracker is preferred for this reaction although this reaction proceeds well at temperatures as low as 120°C. This characteristic of 4-HT is not observed with other non-TEMPO acrylic acid inhibitors, e.g., PTZ or HQ. This means that 4-HT not only prevents fouling in the purification system but also converts a reactor by-product into product in the purification system thus maximizing yields. The typical concentration of 4-HT in either the finishing column reboiler or dimer cracker is at least 500, preferably at least 1,000 and more preferably at least 2,000, ppm. Because 4-HT is a high boiler, it tends to concentrate in the reboiler of a finishing tower which can be equipped with a dimer cracker. The typical temperature for cracking the dimer in the presence of 4-HT is at least 150, preferably at least 170 and more preferably at least 200, °C.
- The following examples further illustrate the invention. Unless otherwise noted, all parts and percentages are by weight.
- Ten milliliter samples of purified acrylic acid (containing known amounts of inhibitor) are placed in DOT (Department of Transportation) tubes. DOT tubes are 10 mL glass ampoules equipped with a 150 mm (6 inch) long, 6 mm (¼ inch) diameter glass tubing neck, which are fitted with 6 mm (¼ inch) Swageloktm nylon caps. The caps are used to support the tubes which extend through twelve 10 mm (3/8 inch) holes in a 150 mm (6 inch) diameter circular plastic block that is about 25 mm (one inch) thick. The block is attached by an offset center support rod to an overhead stirrer. The bulb portion of the tubes are then submerged in a constant temperature silicon oil bath held at 113°C for 72 hours while being rotated (via the overhead stirrer) at about 50 rpm. The tubes are visually monitored during this time for signs of polymer formation (i.e. cloudiness, presence of solids or increased viscosity). The amount of time until first signs of polymer formation is defined as the induction time (or on-set time). Each run consists of six replicate DOT tubes, and the induction time is the average of these six replicates.
- Two glass Fischer & Porter pressure tubes (80 mL volume) are charged with 50 mL of the following aqueous solutions:
- a) 10% acetic acid / 5% acrylic acid / 1000 ppm HQ / 10 ppm Mn(II) / balance water
- b) 10% acetic acid / 5% acrylic acid / 500 ppm 4-HT / 10 ppm Mn(II) / balance water.
- The pressure tubes are sealed with pressure heads which are equipped with a pressure gauge. After securing the heads, the tubes are submerged (covering only the liquid level of the tubes) in a constant temperature oil bath at 149°C for 4 hrs with an autogenic pressure of 170 kPa (25 psig). The tubes are visually monitored during this time for the presence of polymer.
- Three liters of Aldrich glacial acrylic acid (inhibited with 200 ppm MeHQ, monomethyl ether of hydroquinone) is placed in a plastic beaker and then allowed to freeze in the refrigerator at 6°C overnight. The next day the frozen acrylic acid is removed from the refrigerator and a center core containing about one quarter of the volume of the material is cut out and removed from the beaker. The contents left in the beaker are warmed in a 20°C water bath to melt the frozen material. After melting the contents are swirled to evenly mix the remaining inhibitor and then again placed in the refrigerator for a second crystallization. This is repeated for a total of three crystallizations, yielding about 1 kg of purified acrylic acid which contained about 50 ppm of MeHQ inhibitor. This material is used for part of the induction time studies.
- A one liter, round-bottom flask is charged with about 400 mL of Aldrich glacial acrylic acid (inhibited with 200 ppm MeHQ). The flask is attached to a rotary evaporator equipped with a 50°C water bath and vacuum pulled (about 20 mm Hg absolute pressure). About 250 mL of distilled acrylic acid is collected in the ice-water cooled receiver. This is melted and then subjected to rotary evaporation again to produce material that contains less than 1 ppm MeHQ and is used for the rest of the induction time studies.
- The following materials, all from Aldrich Chemical Co., are used in these examples.
- Acrylic Acid (99%)
- Copper (II) Acetate (97%)
- Hydroquinone (HQ)(99%)
- Manganese (II) Acetate (tetrahydrate)
- Phenothiazine (PTZ)(>98%)
- 4-Hydroxy TEMPO (4-HT)(solid)
- 4-HT is tested to determine its efficacy as a polymerization inhibitor for acrylic acid. Potential adverse inhibition interactions of 4-HT with the other inhibitors are also evaluated. The results from the standard lab induction time tests are contained in Table I. All tests are run at 113°C, the maximum reboiler wall temperature expected in a solvent removal tower. Also all tests are conducted under an air headspace.
TABLE I Inhibitor Induction Times 4-HT (ppm) HQ (ppm) PTZ (ppm) MeHQ (ppm) Mn (II)d (ppm) Cu (II)e (ppm) Temp (°C) Induction Time (hrs) 50 0 0 0 0 0 113 30-46b 50 0 0 0 1 0 113 >72a 50 0 0 50 0 0 113 30-46b 50 0 0 50 1 0 113 >72a 50 0 0 0 1 1 113 >72a 50 0 0 50 1 1 113 >72a 50 0 50 0 1 113 30 50 100 0 50 10 0 113 >72a 50 100 100 50 0 113 >72a 100 0 0 50 0 0 113 54 0 100 0 50 0 113 1.5 0 0 100 50 0 0 113 30-46b 100 0 100 50 0 0 113 51 100 100 0 50 10 0 113 55-70c 100 0 0 50 10 0 113 >72a 100 100 1000 50 0 0 113 55-70c 0 100 0 50 10 0 113 >728 3000 3000 0 50 0 0 113 >72a 0 0 0 0 1 0 113 4.5 a) Super stabilized, >90% of acrylic acid had undergone Michael additions
b) All samples polymerized overnight between 30 and 46 hours
c) All samples polymerized overnight between 55 and 70 hours
d) Mn(II) ion concentration in solution (was added as manganese acetate)
e) Cu(II) ion concentration in solution (was added as cupric acetate) - Induction times are directly related to inhibitor efficacy (i.e. a longer induction time is observed for better inhibitors). The data in Table I clearly show that on a per pound basis, 4-HT is significantly better than HQ. In fact, it is at least an order of magnitude better than HQ. Also, 4-HT appears to be better than PTZ (a commonly used acrylic acid process inhibitor). Surprisingly, a synergistic effect between 4-HT and Mn(II) in the presence of oxygen is demonstrated. This effect has not been reported in the open literature. An inhibitor package consisting of 50 ppm 4-HT and 1 ppm of Mn(II) in the presence of oxygen provides super stabilization, i.e., the acrylic acid contains sufficient inhibitor to allow most of the acrylic acid to undergo dimerization before vinyl polymerization occurs. In other words, the induction time exceeds the amount of time it take for >90% of the acrylic acid to undergo Michael additions (which means that after 72 hours at 113°C very little free acrylic acid is still present). However, the acrylic acid dimer can also polymerize to give a clear glassy solid if heating is continued for an extended period.
- This synergistic effect between 4-HT and Mn(II) is similar to the synergistic effect that has been documented for HQ (or MeHQ) and Mn(II). Previous studies have shown that 100 ppm HQ and 1 ppm Mn(II) also provides super stabilization for acrylic acid. However, the inhibitor of this invention achieved super stabilization with half as much 4-HT as HQ at the 1 ppm Mn(II) level. This means that the 50 ppm 4-HT and 1 ppm Mn(II) inhibitor package can be substituted for a commercial HQ/Mn package with no loss of efficacy.
- The data in Table I also demonstrate an absence of negative interactions, i.e., loss of inhibitor capability, between 4-HT and the preferred process co-inhibitor (PTZ) and as such, these can be mixed as desired. This can result in an improvement for those areas of the tower in which phasing may occur because of the increased solubility of 4-HT in water (1 part 4-HT in 1 part water) compared to the less soluble HQ (1 part HQ in 14 parts water).
- The Fischer & Porter pressure tube test is a simulation of conditions expected in steam generators. After fours hours at 149°C the synthetic reaction water (85% water / 10% acetic acid / 5% acrylic acid) shows no signs of vinyl polymerization for either the 4-HT/Mn(II) or HQ/Mn(II) inhibited solutions. This means that both inhibitor packages provide vinyl polymerization protection for times significantly greater than commercial steam generator residence times. In both cases the inhibitor concentration employed (1000 ppm HQ / 10 ppm Mn+2 and 500 ppm 4-HT / 10 ppm Mn+2) are those expected (based on unit mass balance) if a 100 ppm HQ / 1 ppm Mn (II) inhibitor package is replaced with a 50 ppm 4-HT / 1 ppm Mn (II) inhibitor package. This test simulates a steam generator residue and reflects the fact that the inhibitors would be concentrated in this stream.
- Although the invention has been described in considerable detail, this detail is for the purpose of illustration only and the skilled person understands that modifications are possible within the scope of the appended claims.
Claims (12)
- A method of inhibiting the vinyl polymerization of acrylic acid or methacrylic acid in an aqueous solution and in the presence of oxygen, the method comprising the step of mixing with the aqueous solution an inhibitor comprising (i) at least 50 ppm of an N-oxyl compound, and (ii) a manganese ion, the N-oxyl compound and manganese ion present in a N-oxyl compound to manganese ion weight ratio of 50:1 to less than 100:1 based on the acrylic acid or methacrylic acid.
- A method of Claim 1 in which the N-oxyl compound is 4-hydroxy TEMPO.
- A method of Claim 1 or 2 in which the manganese ion has a +2 valence.
- A method of Claim 3 in which the aqueous solution is within a quench tower.
- A method of Claim 3 in which the aqueous solution is within a distillation tower, the tower (i) comprising or in combination with at least one of a reboiler, base section, condenser and flasher, and (ii) containing a gas, and air is fed to the tower through the reboiler or base.
- A method of Claim 5 in which sufficient air is fed to the tower such that the oxygen content within the tower is at least 0.1 mole percent of the gas within the tower.
- A method of claim 3, in which the inhibitor is present in the aqueous solution in an amount of at least 100 ppm.
- A method of claim 7, in which the N-oxyl compound and manganese ion are present in a N-oxyl compound to manganese ion weight ratio of 50:1 to less than 75:1.
- A method of claim 8, in which the inhibitor further comprises phenothiazine.
- An inhibitor for stabilizing an aqueous solution of acrylic acid or methacrylic acid against polymerization in the presence of oxygen, the inhibitor comprising an N-oxyl compound and a manganese ion at a weight ratio of 50:1 to less than 100:1.
- An inhibitor of Claim 10 in which the inhibitor comprises (i) a reaction product of the N-oxyl compound and at least one of (meth)acrylic acid, acetic acid and acrylic acid dimer, and (ii) the manganese ion.
- An inhibitor of Claim 10 or 11, in which the N-oxyl compound is 4-hydroxy TEMPO.
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EP13198607.7A EP2786980A1 (en) | 2007-08-31 | 2008-07-29 | Method of decarboxylating maleic acid to acrylic acid |
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US96921507P | 2007-08-31 | 2007-08-31 | |
PCT/US2008/071474 WO2009032427A2 (en) | 2007-08-31 | 2008-07-29 | Method of inhibiting polymerization and fouling in acrylic acid and acrylate processes |
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EP13198607.7A Division-Into EP2786980A1 (en) | 2007-08-31 | 2008-07-29 | Method of decarboxylating maleic acid to acrylic acid |
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EP13198607.7A Withdrawn EP2786980A1 (en) | 2007-08-31 | 2008-07-29 | Method of decarboxylating maleic acid to acrylic acid |
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EP (2) | EP2197827B1 (en) |
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WO2012121836A1 (en) * | 2011-03-09 | 2012-09-13 | Dow Global Technologies Llc | Synergistic polymerization inhibitor composition and method |
US9370571B2 (en) | 2011-05-19 | 2016-06-21 | Mitsubishi Rayon Co., Ltd. | Aqueous acrylamide solution, stabilizer for aqueous acrylamide solution, and stabilization method for aqueous acrylamide solution |
CN107074990B (en) | 2014-10-14 | 2019-08-23 | 艺康美国股份有限公司 | The fouling and reunion of polymer during reduction acrylate/salt/methacrylate/salt |
EP3012244A1 (en) | 2014-10-24 | 2016-04-27 | Sulzer Chemtech AG | Process and apparatus for purification of acrylic acid |
US9914701B2 (en) | 2015-03-18 | 2018-03-13 | Ecolab Usa Inc. | Use of stable lipophilic hydroxylamine compounds for inhibiting polymerization of vinyl monomers |
JP6705120B2 (en) * | 2015-03-26 | 2020-06-03 | 三菱ケミカル株式会社 | Method for preventing polymerization of acrylic acid and its ester |
US9957209B2 (en) | 2015-03-31 | 2018-05-01 | Ecolab Usa Inc. | Use of quinone methides as antipolymerants for vinylic monomers |
JP6843067B2 (en) | 2015-04-20 | 2021-03-17 | エコラブ ユーエスエイ インク | Method of Inhibiting Polymerization of Unsaturated Monomers |
US10640449B2 (en) | 2016-12-20 | 2020-05-05 | Dow Global Technologies Llc | Methods of using N-oxyl polymerization inhibitor in a wash settler for preparing methyl methacrylate |
WO2023241995A1 (en) * | 2022-06-17 | 2023-12-21 | Basf Se | Storage and/or transport of ethylenically unsaturated carboxylic acids |
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CH364501A (en) * | 1956-08-31 | 1962-09-30 | Union Chimique Belge Sa | Acrylic acid manufacturing process |
GB933102A (en) * | 1959-11-03 | 1963-08-08 | Exxon Research Engineering Co | Decarboxylation of unsaturated dicarboxylic acids and their derivatives |
DE1195297B (en) * | 1962-01-25 | 1965-06-24 | Roehm & Haas Gmbh | Process for the production of acrylic acid esters by decarboxylating maleic and fumaric acid compounds |
US4638079A (en) * | 1985-01-17 | 1987-01-20 | Mallinckrodt, Inc. | Inhibiting polymerization of ethylenically unsaturated monomers |
TW294658B (en) | 1994-06-02 | 1997-01-01 | Nippon Catalytic Chem Ind | |
JP2725638B2 (en) * | 1994-06-02 | 1998-03-11 | 株式会社日本触媒 | Method for preventing polymerization of (meth) acrylic acid and its ester |
DE19954582A1 (en) * | 1999-11-12 | 2001-01-18 | Basf Ag | Stabilization of radically polymerizable ethylenically unsaturated monomer(s) comprises adding solution of stable N-oxy radical(s) in inert solvent |
US6888025B2 (en) * | 2000-02-14 | 2005-05-03 | Nippon Shokubai, Co. Ltd. | Method for absorbing acrylic acid and method for purifying acrylic acid |
JP2001226320A (en) * | 2000-02-14 | 2001-08-21 | Nippon Shokubai Co Ltd | Method for collecting acrylic acid and method for purifying acrylic acid |
FR2822824B1 (en) * | 2001-04-02 | 2005-01-14 | Atofina | PROCESS FOR PRODUCING 2-ETHYLHEXYL ACRYLATE COMPRISING NEUTRALIZATION BASED ON GROSS |
JP4048076B2 (en) * | 2001-07-10 | 2008-02-13 | 株式会社日本触媒 | Decomposition method of Michael adduct |
JP3990580B2 (en) * | 2002-03-12 | 2007-10-17 | 株式会社日本触媒 | Method for preventing polymerization of (meth) acrylic acid ester |
JP4440518B2 (en) * | 2002-07-16 | 2010-03-24 | 株式会社日本触媒 | Acrylic acid production method |
DE102004008575A1 (en) * | 2004-02-19 | 2005-09-08 | Stockhausen Gmbh | Cleavage of oligomeric (meth) acrylic acid in the liquid phase under pressure |
KR100932467B1 (en) * | 2005-12-06 | 2009-12-17 | 니폰 쇼쿠바이 컴파니 리미티드 | Method of producing acrylic acid |
US8242308B2 (en) * | 2006-09-15 | 2012-08-14 | Arkema Inc. | Process for producing acrylic acid |
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JP2015232052A (en) | 2015-12-24 |
US20130178652A1 (en) | 2013-07-11 |
WO2009032427A3 (en) | 2009-05-14 |
KR20150133860A (en) | 2015-11-30 |
KR20100067090A (en) | 2010-06-18 |
KR101665362B1 (en) | 2016-10-12 |
JP2014024855A (en) | 2014-02-06 |
US20160122643A1 (en) | 2016-05-05 |
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WO2009032427A2 (en) | 2009-03-12 |
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