EP2167961A4 - Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique - Google Patents

Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique

Info

Publication number
EP2167961A4
EP2167961A4 EP08772081A EP08772081A EP2167961A4 EP 2167961 A4 EP2167961 A4 EP 2167961A4 EP 08772081 A EP08772081 A EP 08772081A EP 08772081 A EP08772081 A EP 08772081A EP 2167961 A4 EP2167961 A4 EP 2167961A4
Authority
EP
European Patent Office
Prior art keywords
beta2
microglobulin
crp
biomarkers
artery disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08772081A
Other languages
German (de)
English (en)
Other versions
EP2167961A1 (fr
Inventor
John P Cooke
Andrew Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP2167961A1 publication Critical patent/EP2167961A1/fr
Publication of EP2167961A4 publication Critical patent/EP2167961A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
EP08772081A 2007-06-27 2008-06-26 Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique Withdrawn EP2167961A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94668107P 2007-06-27 2007-06-27
PCT/US2008/068430 WO2009003142A1 (fr) 2007-06-27 2008-06-26 Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique

Publications (2)

Publication Number Publication Date
EP2167961A1 EP2167961A1 (fr) 2010-03-31
EP2167961A4 true EP2167961A4 (fr) 2010-07-21

Family

ID=40186040

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08772081A Withdrawn EP2167961A4 (fr) 2007-06-27 2008-06-26 Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique

Country Status (3)

Country Link
US (1) US8227201B2 (fr)
EP (1) EP2167961A4 (fr)
WO (1) WO2009003142A1 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007106466A2 (fr) 2006-03-11 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Bêta-2 microglobuline utilisée comme biomarqueur pour des maladies artérielles périphériques
SG10201704689XA (en) 2008-01-18 2017-07-28 Harvard College Methods of detecting signatures of disease or conditions in bodily fluids
US20100260668A1 (en) * 2008-04-29 2010-10-14 Abbott Laboratories Dual Variable Domain Immunoglobulins and Uses Thereof
EP2282769A4 (fr) * 2008-04-29 2012-04-25 Abbott Lab Immunoglobulines à double domaine variable et utilisations
KR20110016959A (ko) * 2008-06-03 2011-02-18 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
JP2011523853A (ja) * 2008-06-03 2011-08-25 アボット・ラボラトリーズ 二重可変ドメイン免疫グロブリン及びその使用
SG192489A1 (en) * 2008-07-08 2013-08-30 Abbott Lab Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
MX2011011670A (es) * 2009-05-01 2011-11-18 Abbott Lab Inmunoglobulinas de dominio variable dual y usos de las mismas.
UY32808A (es) * 2009-07-29 2011-02-28 Abbott Lab Inmunoglobulinas como dominio variable dual y usos de las mismas
SG178602A1 (en) * 2009-09-01 2012-04-27 Abbott Lab Dual variable domain immunoglobulins and uses thereof
BR112012008833A2 (pt) * 2009-10-15 2015-09-08 Abbott Lab imunoglobulinas de dominio variavel duplo e usos das mesmas
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
GB201004442D0 (en) * 2010-03-17 2010-05-05 Binding Site Group The Biomarker
GB201012049D0 (en) 2010-07-19 2010-09-01 Binding Site Group The Ltd Competition assay
WO2012012717A1 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Méthodes de dépistage de maladies ou d'affections prénatales ou liées à la grossesse
EP2596116A4 (fr) 2010-07-23 2014-03-19 Harvard College Procédés de détection de maladies/pathologies auto-immunes ou liées au système immunitaire
AU2011280996B2 (en) 2010-07-23 2017-03-30 President And Fellows Of Harvard College Methods for detecting signatures of disease or conditions in bodily fluids
MX2013000917A (es) 2010-07-23 2013-07-05 Harvard College Metodos para detectar las enfermedades o condiciones usando celulas fagociticas.
EP2596349B1 (fr) 2010-07-23 2017-12-13 President and Fellows of Harvard College Méthodes de détection de maladies ou de pathologies cardiovasculaires
MX341579B (es) 2010-08-03 2016-08-25 Abbvie Inc * Inmunoglobulinas de dominio variable doble y usos de las mismas.
AU2011293253B2 (en) 2010-08-26 2014-12-11 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
CA2861610A1 (fr) 2011-12-30 2013-07-04 Abbvie Inc. Proteines a double liaison specifique dirigees contre l'il-13 et/ou l'il-17
SG11201408383SA (en) 2012-06-15 2015-01-29 Harry Stylli Methods of detecting diseases or conditions using circulating diseased cells
CA2876731A1 (fr) 2012-06-15 2013-12-19 Harry Stylli Procedes de detection de maladies ou d'etats
TW202210507A (zh) 2012-11-01 2022-03-16 美商艾伯維有限公司 抗-vegf/dll4雙重可變區域免疫球蛋白及其用途
EP4202441A3 (fr) 2013-03-09 2023-07-26 Immunis.AI, Inc. Profil d'expression génétique dans les macrophages pour le diagnostic du cancer
EP3385717A3 (fr) 2013-03-09 2018-10-24 Harry Stylli Procédés de detection du cancer de la prostate
US9062108B2 (en) 2013-03-15 2015-06-23 Abbvie Inc. Dual specific binding proteins directed against IL-1 and/or IL-17
EP3004882B1 (fr) 2013-06-06 2018-03-21 Koninklijke Philips N.V. Réactifs, procédés et dispositifs pour prévenir l'agrégation dans des essais portant sur des particules destinés à détecter des molécules cibles multimères
EP4075139A1 (fr) 2014-09-11 2022-10-19 Harry Stylli Procédés de détection du cancer de la prostate
US10093733B2 (en) 2014-12-11 2018-10-09 Abbvie Inc. LRP-8 binding dual variable domain immunoglobulin proteins
EP3289107A4 (fr) 2015-05-01 2018-09-12 The University of British Columbia Biomarqueurs pour la détection du rejet aigu de greffe du coeur
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
US11612888B2 (en) * 2017-01-04 2023-03-28 The Research Foundation For The State University Of New York Biomarker detection device
US20220229071A1 (en) * 2017-11-02 2022-07-21 Prevencio, Inc. Diagnostic and prognostic methods for peripheral arterial diseases, aortic stenosis, and outcomes
US20230279120A1 (en) * 2021-11-09 2023-09-07 Truebinding, Inc. Methods of treating or inhibiting cardiovascular diseases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007106466A2 (fr) * 2006-03-11 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Bêta-2 microglobuline utilisée comme biomarqueur pour des maladies artérielles périphériques
WO2008057966A2 (fr) * 2006-11-01 2008-05-15 Vermillion, Inc. Panel de biomarqueurs de maladie d'artères périphériques

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001002866A1 (fr) 1999-02-19 2001-01-11 University Of Iowa Research Foundation Procedes de diagnostic et de therapie pour les maladies affectant la paroi arterielle
US20030149997A1 (en) * 1999-02-19 2003-08-07 Hageman Gregory S. Diagnostics and therapeutics for arterial wall disruptive disorders
JP2005053728A (ja) 2003-08-01 2005-03-03 Dsl Japan Co Ltd 高吸油性および高い構造性を有する非晶質シリカ粒子
WO2005121758A1 (fr) * 2004-06-03 2005-12-22 Ciphergen Biosystems, Inc. Biomarqueurs pour l'arteriopathie peripherique (ap)
EP1615036B1 (fr) 2004-07-07 2007-09-19 F.Hoffmann-La Roche Ag Combinaison de marqueurs pour le diabète de type 1 et 2

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007106466A2 (fr) * 2006-03-11 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Bêta-2 microglobuline utilisée comme biomarqueur pour des maladies artérielles périphériques
WO2008057966A2 (fr) * 2006-11-01 2008-05-15 Vermillion, Inc. Panel de biomarqueurs de maladie d'artères périphériques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2009003142A1 *
WILSON ANDREW M ET AL: "beta 2-microglobulin as a biomarker in peripheral arterial disease - Proteomic profiling and clinical studies", CIRCULATION, vol. 116, no. 12, September 2007 (2007-09-01), pages 1396 - 1403, XP002583808, ISSN: 0009-7322 *

Also Published As

Publication number Publication date
US8227201B2 (en) 2012-07-24
WO2009003142A1 (fr) 2008-12-31
US20090042214A1 (en) 2009-02-12
EP2167961A1 (fr) 2010-03-31

Similar Documents

Publication Publication Date Title
EP2167961A4 (fr) Bêta-2-microglobuline et protéine c réactive (crp) en tant que biomarqueurs pour une maladie artérielle périphérique
GB0715171D0 (en) Sample processor
EP2083274A4 (fr) Appareil d'analyse du sang
EP1961382A4 (fr) Appareil pour analyses sanguines
ZA201000095B (en) Multiple analysis of blood samples
EP2158326A4 (fr) Marqueurs biologiques pour le diagnostic d'une maladie auto-immune
GB0706820D0 (en) Blood grouop antibody screening
EP2115664A4 (fr) Analyse quantitative sur des caractéristiques cutanées
EP2316030A4 (fr) Procédés de criblage de protéines
EP1997434A4 (fr) Dispositif d'examen sanguin
GB0504767D0 (en) Lipocalin protein
EP2168481A4 (fr) Dispositif d'analyse de sang
EP1997432A4 (fr) Dispositif de test sanguin
EP2346387B8 (fr) Analyse de sang
EP2001362A4 (fr) Tomographie opto-acoustique quantitative à contraste amélioré
WO2010141469A9 (fr) Biomarqueurs de protéine et cibles thérapeutiques pour maladies autoimmunes et alloimmunes
WO2008016652A9 (fr) Imagerie de vaisseaux sanguins et ses utilisations
IL193604A0 (en) Methods of using antibodies against human il-22
EP2035830A4 (fr) Complexe proteine/peptide lie a l'albumine en tant que biomarqueur pour une maladie
LT2135075T (lt) Viso kraujo tyrimas
EP2352035A4 (fr) Micropuce et appareil d analyse
GB0815576D0 (en) Analysis of glycated proteins
EP2109688A4 (fr) Proteine de liaison a la galectine-3 en tant que biomarqueur de maladie cardiovasculaire
EP2260107A4 (fr) Analyses permettant de diagnostiquer et d évaluer des options de traitement pour la maladie de pompe
EP2210113A4 (fr) Procédés de détection de l'hémoglobine glyquée

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20100104

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/68 20060101ALI20100601BHEP

Ipc: G01N 33/53 20060101AFI20090123BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20100617

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1142957

Country of ref document: HK

17Q First examination report despatched

Effective date: 20110308

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20111213

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1142957

Country of ref document: HK