EP2150806A4 - Procédés et systèmes d'analyse de matière fluorescente à autofluorescence limitée - Google Patents
Procédés et systèmes d'analyse de matière fluorescente à autofluorescence limitéeInfo
- Publication number
- EP2150806A4 EP2150806A4 EP08767652A EP08767652A EP2150806A4 EP 2150806 A4 EP2150806 A4 EP 2150806A4 EP 08767652 A EP08767652 A EP 08767652A EP 08767652 A EP08767652 A EP 08767652A EP 2150806 A4 EP2150806 A4 EP 2150806A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- systems
- methods
- fluorescent materials
- analyzing fluorescent
- reduced autofluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92861707P | 2007-05-10 | 2007-05-10 | |
US11/901,273 US20080277595A1 (en) | 2007-05-10 | 2007-09-14 | Highly multiplexed confocal detection systems and methods of using same |
PCT/US2008/005953 WO2008140758A1 (fr) | 2007-05-10 | 2008-05-09 | Procédés et systèmes d'analyse de matière fluorescente à autofluorescence limitée |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2150806A1 EP2150806A1 (fr) | 2010-02-10 |
EP2150806A4 true EP2150806A4 (fr) | 2013-01-02 |
Family
ID=41382245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08767652A Withdrawn EP2150806A4 (fr) | 2007-05-10 | 2008-05-09 | Procédés et systèmes d'analyse de matière fluorescente à autofluorescence limitée |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2150806A4 (fr) |
AU (1) | AU2008251861B2 (fr) |
CA (1) | CA2687062C (fr) |
WO (1) | WO2008140758A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080277595A1 (en) * | 2007-05-10 | 2008-11-13 | Pacific Biosciences Of California, Inc. | Highly multiplexed confocal detection systems and methods of using same |
US9637380B2 (en) | 2008-03-31 | 2017-05-02 | Pacific Biosciences Of California, Inc. | Nanoscale apertures having islands of functionality |
CA2720247C (fr) | 2008-03-31 | 2020-07-14 | Pacific Biosciences Of California, Inc. | Procedes et compositions de charge de molecule individuelle |
CA2738626C (fr) | 2008-09-30 | 2017-08-08 | Pacific Biosciences Of California, Inc. | Systemes analytiques a multiplexage ultra-eleve et procedes |
US8367159B2 (en) | 2009-09-11 | 2013-02-05 | Pacific Biosciences Of California, Inc. | Methods for producing ZMWs with islands of functionality |
US8906670B2 (en) | 2009-09-11 | 2014-12-09 | Pacific Bioscience Of California, Inc. | Zero-mode waveguides with non-reflecting walls |
WO2011048539A1 (fr) | 2009-10-23 | 2011-04-28 | Koninklijke Philips Electronics N.V. | Dispositif pour surveiller une pluralité de signaux discrets de fluorescence |
US9331113B2 (en) | 2010-05-03 | 2016-05-03 | The Regents Of The University Of California | Wide-field lensless fluorescent imaging on a chip |
WO2014194028A1 (fr) * | 2013-05-31 | 2014-12-04 | Pacific Biosciences Of California, Inc | Dispositifs d'analyse possédant des réseaux de trains de lentilles compacts |
EP3044538B1 (fr) | 2013-09-10 | 2021-06-30 | BAE Systems PLC | Mesure optique de rugosité de surface |
US11378544B2 (en) | 2018-01-08 | 2022-07-05 | Illumina, Inc. | High-throughput sequencing with semiconductor-based detection |
NL2020621B1 (en) * | 2018-01-08 | 2019-07-15 | Illumina Inc | Multiplexing of an active sensor detector using structured illumination |
SG11201911784PA (en) | 2018-01-08 | 2020-01-30 | Illumina Inc | Systems and devices for high-throughput sequencing with semiconductor-based detection |
CN108181290B (zh) * | 2018-03-24 | 2020-07-10 | 王碧 | 一种荧光定量分析仪 |
CN116360086A (zh) * | 2019-10-21 | 2023-06-30 | 因美纳有限公司 | 用于结构化照明显微术的系统和方法 |
EP4379355A1 (fr) * | 2022-11-29 | 2024-06-05 | Gnothis Holding AG | Analyse à haut débit d'événements de molécule unique |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
WO2003001178A2 (fr) * | 2001-06-20 | 2003-01-03 | Arryx, Inc. | Jeu ordonne tridimensionnel dynamique de sondes |
US20040126780A1 (en) * | 2001-05-29 | 2004-07-01 | Rudolf Rigler | Use of optical diffraction elements in detection methods |
US20060011859A1 (en) * | 2004-07-16 | 2006-01-19 | Ralf Wolleschensky | Procedure for the optical acquisition of objects by means of a light raster microscope |
US20060214106A1 (en) * | 2005-03-01 | 2006-09-28 | Ralf Wolleschensky | Point scanning laser scanning microscope and methods for adjustment of a microscope |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001002850A1 (fr) * | 1999-07-06 | 2001-01-11 | Caliper Technologies Corp. | Systemes et methodes microfluidiques permettant de determiner la cinetique d'un modulateur |
US20030031596A1 (en) * | 2001-08-09 | 2003-02-13 | Yokogawa Electric Corporation | Biochip reader and fluorometric imaging apparatus |
EP3415641B1 (fr) * | 2004-09-17 | 2023-11-01 | Pacific Biosciences Of California, Inc. | Procédé d'analyse de molécules |
EP1889111A2 (fr) * | 2005-05-25 | 2008-02-20 | Massachusetts Institute of Technology | Systemes d'imagerie multifocaux et procedes associes |
-
2008
- 2008-05-09 WO PCT/US2008/005953 patent/WO2008140758A1/fr active Application Filing
- 2008-05-09 CA CA2687062A patent/CA2687062C/fr active Active
- 2008-05-09 EP EP08767652A patent/EP2150806A4/fr not_active Withdrawn
- 2008-05-09 AU AU2008251861A patent/AU2008251861B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
US20040126780A1 (en) * | 2001-05-29 | 2004-07-01 | Rudolf Rigler | Use of optical diffraction elements in detection methods |
WO2003001178A2 (fr) * | 2001-06-20 | 2003-01-03 | Arryx, Inc. | Jeu ordonne tridimensionnel dynamique de sondes |
US20060011859A1 (en) * | 2004-07-16 | 2006-01-19 | Ralf Wolleschensky | Procedure for the optical acquisition of objects by means of a light raster microscope |
US20060214106A1 (en) * | 2005-03-01 | 2006-09-28 | Ralf Wolleschensky | Point scanning laser scanning microscope and methods for adjustment of a microscope |
Non-Patent Citations (4)
Title |
---|
GOSCH M ET AL: "Parallel dual-color fluorescence cross-correlation spectroscopy using diffractive optical elements", JOURNAL OF BIOMEDICAL OPTICS SPIE USA, vol. 10, no. 5, September 2005 (2005-09-01), pages 54008 - 1, XP040213852, ISSN: 1083-3668 * |
JOHANSSON M ET AL: "DESIGN, FABRICATION, AND EVALUATION OF A MULTICHANNEL DIFFRACTIVE OPTIC ROTARY JOINT", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC; US, vol. 38, no. 8, 10 March 1999 (1999-03-10), pages 1302 - 1310, XP000823450, ISSN: 0003-6935, DOI: 10.1364/AO.38.001302 * |
K SVOBODA ET AL: "Biological Applications of Optical Forces", ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, vol. 23, no. 1, 1 June 1994 (1994-06-01), pages 247 - 285, XP055010743, ISSN: 1056-8700, DOI: 10.1146/annurev.bb.23.060194.001335 * |
See also references of WO2008140758A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2008251861B2 (en) | 2014-03-20 |
WO2008140758A1 (fr) | 2008-11-20 |
AU2008251861A1 (en) | 2008-11-20 |
EP2150806A1 (fr) | 2010-02-10 |
CA2687062C (fr) | 2016-04-12 |
CA2687062A1 (fr) | 2008-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20091127 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA MK RS |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: TURNER, STEPHEN Inventor name: ZHAO, PEGIAN Inventor name: ZACCARIN, DENIS Inventor name: ZHONG, CHENG-FRANK Inventor name: LUNDQUIST, PAUL |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: TURNER, STEPHEN Inventor name: ZHAO, PEGIAN Inventor name: ZACCARIN, DENIS Inventor name: ZHONG, CHENG-FRANK Inventor name: LUNDQUIST, PAUL |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20121203 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 24/00 20060101ALI20121127BHEP Ipc: G01N 21/76 20060101AFI20121127BHEP Ipc: G02B 21/00 20060101ALI20121127BHEP Ipc: G01N 21/64 20060101ALI20121127BHEP |
|
17Q | First examination report despatched |
Effective date: 20130828 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20140108 |