EP2139552A1 - Nahthülle und verfahren zur implantation von einer oder mehr elektrischen leitungen in einer vene - Google Patents

Nahthülle und verfahren zur implantation von einer oder mehr elektrischen leitungen in einer vene

Info

Publication number
EP2139552A1
EP2139552A1 EP07716089A EP07716089A EP2139552A1 EP 2139552 A1 EP2139552 A1 EP 2139552A1 EP 07716089 A EP07716089 A EP 07716089A EP 07716089 A EP07716089 A EP 07716089A EP 2139552 A1 EP2139552 A1 EP 2139552A1
Authority
EP
European Patent Office
Prior art keywords
suture sleeve
suture
hole
vein
lead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07716089A
Other languages
English (en)
French (fr)
Other versions
EP2139552B1 (de
EP2139552A4 (de
Inventor
Johan Eckerdal
Rolf Hill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Medical AB
Original Assignee
St Jude Medical AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Jude Medical AB filed Critical St Jude Medical AB
Publication of EP2139552A1 publication Critical patent/EP2139552A1/de
Publication of EP2139552A4 publication Critical patent/EP2139552A4/de
Application granted granted Critical
Publication of EP2139552B1 publication Critical patent/EP2139552B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A61N1/057—Anchoring means; Means for fixing the head inside the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A61N1/057—Anchoring means; Means for fixing the head inside the heart
    • A61N2001/0582—Suture sleeves

Definitions

  • the invention relates to a suture sleeve for one or more implantable leads, the suture sleeve being adapted to be inserted into a vein to secure and protect the one or more leads from damage when a suture thread is posi- tioned and tied around the vein in the region over the suture sleeve to secure the suture sleeve and prevent bleeding from the vein, comprising two or more lead receiving through holes, into each of which a medical implantable lead may be inserted.
  • the invention also relates to a method for implanting one or more electrical leads into a vein.
  • an electrical lead into a vein in an animal or human body, such that the lead extends out from the vein. This is the case e.g. when implanting a pacemaker into a body for monitoring and controlling the heart function.
  • the pacemaker itself is implanted just under the skin in a pacemaker pocket at a suitable position, whereas one or more leads are inserted through an opening in the wall of a vein and pushed in until a distal end enters the heart where it can be attached to the heart wall.
  • the vein must be closed after lead inser- tion to avoid bleeding and the lead must be fixated in relation to the vein to eliminate the risk that the lead accidentally can be drawn out from its position. Avoiding bleeding is very important to prevent local haematoma since haematoma is considered as a major positive predic- tor for infection in the pacemaker pocket. This is accomplished by means of a suture thread, which is positioned around the vein and the lead in the area of the cut opening in the wall of the vein and which is tied around the vein and the lead.
  • a suture thread which is positioned around the vein and the lead in the area of the cut opening in the wall of the vein and which is tied around the vein and the lead.
  • the suture stress will be concentrated to a small area and may cause intensive abrasion load to the lead body. On the other hand, if the suture is not tight enough, bleeding may occur and cause haematoma. If the suture is not combined with fixation of the lead else- where, there is also a risk for longitudinal lead movement and lead dislodgment if the suture is not sufficient tight.
  • suture sleeve which is positioned around the lead in the area of the lead-through in the wall of the vein. In this way the suture sleeve will protect the lead from damage by the suture thread and the suture sleeve will fixate the lead in a sufficient degree.
  • one lead is positioned in each of the lead receiving channels and then the flexible strip is wrapped around the leads.
  • the suture sleeve is positioned in the cut opening in the vein and tied around by a suture thread.
  • a suture sleeve it is not possible to position and fixate only one or two leads in a suture sleeve, which is adapted for three leads, since then blood will leak out through the channel which has no lead positioned therein. I.e.
  • the invention also relates to a method for implanting one or more electrical leads into a vein of a human or animal body, having essentially the same object as above. At least this object is achieved by means of a method according to claim 11.
  • the basis of the invention is the insight that the above object may be achieved by means of a suture sleeve having two or more lead receiving through holes. At least all the holes except one are provided with sealing means, which are easy to break or remove when it is desirable to insert a lead into a specific hole. Accordingly, as long as no lead is inserted into a hole and the sealing means is intact, the sealing means prevents any blood leakage through that hole.
  • the sealing means is in form of a thin membrane, of e.g. silicone, which easily can be broken.
  • the sealing means also could be in any other suitable form, e.g. as a removable plug or the like in the hole. Normally, this is not a preferred embodiment, since small removable items in connection with an open cut in a body, could constitute a risk that the item is lost in the cut.
  • the membrane and the plug or the like could be manufactured as a separate detail and attached in the hole of the suture sleeve by means of for example an adhesive.
  • the through holes in the suture sleeve can be made as complete and unbroken holes, in which case the leads are inserted by displacing the leads in the axial direction of each hole.
  • a sealing means in form of a membrane can be broken by means of the lead when it is inserted into the hole.
  • a prerequisite for forming the suture sleeve in this way is that the lead is substantial isodiametric along its entire length.
  • the leads have a thickened portion, e.g. in their tip portions.
  • the suture sleeve is formed of an elastic material.
  • the slot formed through holes are each provided with a sealing means in form of a membrane, which will brake when deflecting the material around the hole and widening the slot.
  • one of the through holes can, as in the described and illustrated embodiment, be unbroken and adapted to be pre-assembled onto a lead. In this way there is no risk of losing the suture sleeve during an implantation.
  • the suture sleeve could be manufactured with an arbitrary number of holes, however at least two. Normally it is sufficient to manufacture the suture sleeve with three holes since this will cover most appli- cation ranges for pacemakers. Then it is possible to attach one, two or three electrical leads, as desired, in a secured and bleeding preventing way.
  • Fig 1 is a perspective view of suture sleeve according to the invention
  • Fig 2 is an end view of the suture sleeve in fig 1
  • Fig 3 is an end view according to fig 2 with the material around a slot in one of the through holes deflected outwards;
  • Fig 4 is a perspective view showing the suture sleeve, with two electrical leads in it, inserted into an opening in a vein and tied around with a suture thread.
  • a suture sleeve 1 according to the inven- tion is shown in a perspective view and an end view, respectively.
  • the suture sleeve has an elongated form with a generally circular cross section and is provided with a truncated conical shape in each end to facilitate introducing into an opening in a vein.
  • the suture sleeve comprises three through holes 2,
  • the suture sleeve is adapted to be pre- assembled onto one electrical lead 4 such that the lead extends through the unbroken through hole 2. In this way the suture sleeve will be held safely on the lead without any risk for it to be lost during implantation.
  • one or two additional leads 4' can optionally be mounted in the suture sleeve by, as is illustrated in fig 3, simply deflecting the material around the slot 3 such that the slot is widened and a lead can be inserted into the through hole 2' sideways.
  • Each of the through holes 2' , 2'' being formed with a slot 3, is provided with a sealing means in form of a thin membrane 5, which blocks the through hole.
  • a sealing means in form of a thin membrane 5, which blocks the through hole.
  • FIG. 4 In fig 4 is illustrated a situation where a suture sleeve 1 is partly inserted into an opening in a vein 6.
  • Two leads 4, 4' are inserted into the vein via a respec- tive through hole 2, 2' in the suture sleeve.
  • the third through hole 2' ' does not accommodate any lead, bleeding is prevented from this through hole owing to the fact that the membrane 5 still is intact in this hole.
  • a suture thread 7 is positioned and tied around the vein 6 and the suture sleeve 1. In this way bleeding is prevented in the region between the suture sleeve and the wall of the vein.
  • the suture sleeve is formed with circumferential grooves 8 around its outer periphery, as is best seen in fig 1, in which the suture thread 7 and vein tissue may sink into when tying the suture thread.

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
EP07716089A 2007-03-26 2007-03-26 Nahthülle zur implantation von einer oder mehr elektrischen leitungen in einer vene Not-in-force EP2139552B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SE2007/000294 WO2008118043A1 (en) 2007-03-26 2007-03-26 A suture sleeve and a method for implanting one or more electrical leads into a vein

Publications (3)

Publication Number Publication Date
EP2139552A1 true EP2139552A1 (de) 2010-01-06
EP2139552A4 EP2139552A4 (de) 2010-08-18
EP2139552B1 EP2139552B1 (de) 2011-05-25

Family

ID=39788714

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07716089A Not-in-force EP2139552B1 (de) 2007-03-26 2007-03-26 Nahthülle zur implantation von einer oder mehr elektrischen leitungen in einer vene

Country Status (4)

Country Link
US (1) US20100036228A1 (de)
EP (1) EP2139552B1 (de)
AT (1) ATE510582T1 (de)
WO (1) WO2008118043A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4836208A (en) * 1985-12-24 1989-06-06 American Home Products Corporation (Del.) Electrode assembly for sensing heart activity
US5107856A (en) * 1991-01-10 1992-04-28 Siemens-Pacesetter, Inc. Multiple lead suture sleeve
US5603730A (en) * 1995-07-19 1997-02-18 Ventritex, Inc. Suture sleeve for implantable lead
US20040059403A1 (en) * 2002-09-24 2004-03-25 Geriche, Inc. Suture sleeve
US20040254623A1 (en) * 2003-06-12 2004-12-16 Cardiac Pacemakers, Inc. Star suture sleeve
US7082337B2 (en) * 2003-12-18 2006-07-25 Medtronic, Inc. Suture sleeve

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO2008118043A1 *

Also Published As

Publication number Publication date
ATE510582T1 (de) 2011-06-15
US20100036228A1 (en) 2010-02-11
WO2008118043A1 (en) 2008-10-02
WO2008118043A8 (en) 2008-12-11
EP2139552B1 (de) 2011-05-25
EP2139552A4 (de) 2010-08-18

Similar Documents

Publication Publication Date Title
EP2129430B1 (de) Nahthülle zur implantation von einer oder mehr leitungen in einer vene
US5603730A (en) Suture sleeve for implantable lead
EP3013405B1 (de) Werkzeug zur aufbringung eines katheterankers
US7651503B1 (en) Endocardial lead cutting apparatus
US8140173B2 (en) Anchoring device for securing intracranial catheter or lead wire to a patient's skull
US9155880B2 (en) Electrode with movable insertion stopper
US7218972B2 (en) Extra strength suture sleeve
US8649881B2 (en) Suture sleeve and a method for manufacturing a suture sleeve
US8000809B2 (en) Device for intracavity stimulation of the left atrium and/or ventricle through atrial transseptal puncture and removal of the catheter proximal end by the retrograde venous route toward the prepectoral region
US5683446A (en) Medical electrical lead having an anchoring sleeve retaining device
US9717894B2 (en) Fixation and protection of an implanted medical device
CN105813604A (zh) 刺激组件的固定特征
WO2017131424A1 (en) Dual needle set having single or multiple gold threads for hair loss treatment
US20040254623A1 (en) Star suture sleeve
EP2139552B1 (de) Nahthülle zur implantation von einer oder mehr elektrischen leitungen in einer vene
EP2271393B1 (de) Nahthülse
US7242986B2 (en) Device and method for a self-attaching suture sleeve
US9550045B2 (en) Repositionable therapy delivery element anchor
KR102217601B1 (ko) 인공 괄약근

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20091026

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20100719

RIC1 Information provided on ipc code assigned before grant

Ipc: A61N 1/05 20060101AFI20081015BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RIC1 Information provided on ipc code assigned before grant

Ipc: A61N 1/05 20060101AFI20101108BHEP

RTI1 Title (correction)

Free format text: A SUTURE SLEEVE FOR IMPLANTING ONE OR MORE ELECTRICAL LEADS INTO A VEIN

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602007014909

Country of ref document: DE

Effective date: 20110707

REG Reference to a national code

Ref country code: NL

Ref legal event code: VDEP

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110926

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110925

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110905

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110826

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20120228

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602007014909

Country of ref document: DE

Effective date: 20120228

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120331

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20120326

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120326

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IE

Payment date: 20130325

Year of fee payment: 7

Ref country code: DE

Payment date: 20130327

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110825

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110525

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120326

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20070326

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602007014909

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602007014909

Country of ref document: DE

Effective date: 20141001

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141001

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140326

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20150327

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20150317

Year of fee payment: 9

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20161130

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160331

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160331

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160331