EP2138787A3 - Mounting - Google Patents

Mounting Download PDF

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Publication number
EP2138787A3
EP2138787A3 EP09007929A EP09007929A EP2138787A3 EP 2138787 A3 EP2138787 A3 EP 2138787A3 EP 09007929 A EP09007929 A EP 09007929A EP 09007929 A EP09007929 A EP 09007929A EP 2138787 A3 EP2138787 A3 EP 2138787A3
Authority
EP
European Patent Office
Prior art keywords
sleeve
carpule
heat transfer
manufacturing tolerances
low manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09007929A
Other languages
German (de)
French (fr)
Other versions
EP2138787A2 (en
Inventor
Gerald Thomas
Jürgen ROTHBAUER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Optima Group pharma GmbH
Original Assignee
Optima Group pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optima Group pharma GmbH filed Critical Optima Group pharma GmbH
Publication of EP2138787A2 publication Critical patent/EP2138787A2/en
Publication of EP2138787A3 publication Critical patent/EP2138787A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
    • F26B25/001—Handling, e.g. loading or unloading arrangements
    • F26B25/003—Handling, e.g. loading or unloading arrangements for articles

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Zur Halterung einer mit einem pharmazeutischen Produkt gefüllten Karpule (1) oder eines sonstigen Produktbehälters für pharmazeutische Produkte vor und während des Gefriertrocknens wird eine Hülse (5,15) vorgeschlagen, die aus Metall besteht und eine ebene mit geringen Fertigungstoleranzen hergestellte Standfläche (7) aufweist. Die Hülse (5,15) weist eine zylindrische Aufnahme (8,18) auf, in die eine Karpule (1) eingesetzt werden kann. Der Boden (10) dieser Aufnahme (8,18) kann Öffnungen (11) aufweisen. Aufgrund der mit geringen Fertigungstoleranzen hergestellten Standfläche (7) der metallischen Hülse (5,15) erfolgt ein besserer Wärmeübergang von der Kühlplatte, auf der die Hülse (5,15) mit der Karpule (1) steht, auf die Hülse (5,15). Von der Hülse (5,15) aus erfolgt ein verbesserter Wärmeübergang auf das Innere der Karpule (1), da diese über die gesamte Länge der Hülse (5,15) ringsum von dem Material der Hülse (5,15) umgeben ist und sich dadurch eine vergrößerte Übergangsfläche bildet, längs der ein Wärmeübergang durch Wärmestrahlung erfolgt. Die Hülse (5,15) reicht vorzugsweise bis zu Flüssigkeitsspiegel des in der Karpule (1) angeordneten pharmazeutischen Produkts.

Figure imgaf001
For holding a filled with a pharmaceutical product carpule (1) or other product container for pharmaceutical products before and during freeze-drying, a sleeve (5,15) is proposed, which consists of metal and a flat manufactured with low manufacturing tolerances standing surface (7) , The sleeve (5,15) has a cylindrical receptacle (8,18) into which a carpule (1) can be inserted. The bottom (10) of this receptacle (8,18) may have openings (11). Due to the manufactured with low manufacturing tolerances standing surface (7) of the metallic sleeve (5,15) there is a better heat transfer from the cooling plate on which the sleeve (5,15) with the carpule (1), on the sleeve (5,15 ). From the sleeve (5,15) from an improved heat transfer to the interior of the carpule (1), since it is surrounded over the entire length of the sleeve (5,15) around by the material of the sleeve (5,15) and itself thereby forms an enlarged transition surface, along which a heat transfer takes place by thermal radiation. The sleeve (5,15) preferably extends to liquid level of the in the carpule (1) arranged pharmaceutical product.
Figure imgaf001
EP09007929A 2008-06-27 2009-06-17 Mounting Withdrawn EP2138787A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102008031809A DE102008031809A1 (en) 2008-06-27 2008-06-27 bracket

Publications (2)

Publication Number Publication Date
EP2138787A2 EP2138787A2 (en) 2009-12-30
EP2138787A3 true EP2138787A3 (en) 2012-02-29

Family

ID=41114847

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09007929A Withdrawn EP2138787A3 (en) 2008-06-27 2009-06-17 Mounting

Country Status (3)

Country Link
US (1) US20100251560A1 (en)
EP (1) EP2138787A3 (en)
DE (1) DE102008031809A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101970964B (en) * 2008-03-19 2012-05-23 株式会社盛本医药 Freeze-drying method and freeze-drying apparatus
WO2018204484A1 (en) * 2017-05-02 2018-11-08 Massachusetts Institute Of Technology Freeze-drying methods and related products
JP2019184152A (en) * 2018-04-09 2019-10-24 株式会社アルバック Holder, and freeze drying system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3571940A (en) * 1969-04-21 1971-03-23 Cenco Medical Health Supply Co Thermal cassette
US6440101B1 (en) * 2000-05-31 2002-08-27 Abbott Laboratories Syringe systems for lyophilized drugs and methods for making the same
US20050171813A1 (en) * 2004-02-04 2005-08-04 Jordan Mchael L. System for identifying and sorting orders
WO2006013360A1 (en) * 2004-08-03 2006-02-09 Micropharm Limited Freeze-drying apparatus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1778456A1 (en) * 1968-04-30 1971-08-26 Martin Christ Kg Method and device for freeze-drying
US4001944A (en) * 1975-08-25 1977-01-11 Parke, Davis & Company Freeze-drying process
US4351158A (en) * 1980-01-22 1982-09-28 American Home Products Corporation Method of producing multicomponent lyophilized product
US4491082A (en) * 1982-04-01 1985-01-01 Ppg Industries, Inc. Cylindrical sleeve applicator for use in manufacturing chemically treated filaments
US5860360A (en) * 1996-12-04 1999-01-19 Day International, Inc. Replaceable printing sleeve
AU7291398A (en) * 1997-05-06 1998-11-27 Thermoceramix, L.L.C. Deposited resistive coatings
US20080034998A1 (en) * 2006-08-08 2008-02-14 Byers Joseph L Method of making a printing blanket or sleeve including cast polyurethane layers
WO2009030342A1 (en) * 2007-08-28 2009-03-12 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Receptacle
US20090166357A1 (en) * 2007-12-28 2009-07-02 Petersen Chris C Wast receptacle

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3571940A (en) * 1969-04-21 1971-03-23 Cenco Medical Health Supply Co Thermal cassette
US6440101B1 (en) * 2000-05-31 2002-08-27 Abbott Laboratories Syringe systems for lyophilized drugs and methods for making the same
US20050171813A1 (en) * 2004-02-04 2005-08-04 Jordan Mchael L. System for identifying and sorting orders
WO2006013360A1 (en) * 2004-08-03 2006-02-09 Micropharm Limited Freeze-drying apparatus

Also Published As

Publication number Publication date
US20100251560A1 (en) 2010-10-07
DE102008031809A1 (en) 2009-12-31
EP2138787A2 (en) 2009-12-30

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