EP2136761A1 - Appareil de type orthèse de pied - Google Patents
Appareil de type orthèse de piedInfo
- Publication number
- EP2136761A1 EP2136761A1 EP08718760A EP08718760A EP2136761A1 EP 2136761 A1 EP2136761 A1 EP 2136761A1 EP 08718760 A EP08718760 A EP 08718760A EP 08718760 A EP08718760 A EP 08718760A EP 2136761 A1 EP2136761 A1 EP 2136761A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- foot
- structures
- subject
- plantar
- disposed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000009023 proprioceptive sensation Effects 0.000 claims abstract description 26
- 230000001965 increasing effect Effects 0.000 claims abstract description 13
- 230000002708 enhancing effect Effects 0.000 claims abstract description 9
- 210000002683 foot Anatomy 0.000 claims description 58
- 210000000459 calcaneus Anatomy 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 8
- AEUTYOVWOVBAKS-UWVGGRQHSA-N ethambutol Natural products CC[C@@H](CO)NCCN[C@@H](CC)CO AEUTYOVWOVBAKS-UWVGGRQHSA-N 0.000 claims description 5
- 210000000988 bone and bone Anatomy 0.000 claims description 4
- 239000004814 polyurethane Substances 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 2
- 229920002635 polyurethane Polymers 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 1
- 210000001640 nerve ending Anatomy 0.000 abstract description 6
- 230000009471 action Effects 0.000 description 4
- 210000004556 brain Anatomy 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 210000003423 ankle Anatomy 0.000 description 3
- 210000000454 fifth toe Anatomy 0.000 description 3
- 210000001255 hallux Anatomy 0.000 description 3
- 210000000474 heel Anatomy 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 230000007774 longterm Effects 0.000 description 2
- 210000001699 lower leg Anatomy 0.000 description 2
- 230000000272 proprioceptive effect Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000004233 talus Anatomy 0.000 description 2
- 206010017577 Gait disturbance Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 210000002082 fibula Anatomy 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 208000018883 loss of balance Diseases 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000007383 nerve stimulation Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 210000001032 spinal nerve Anatomy 0.000 description 1
- 230000003019 stabilising effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 210000000457 tarsus Anatomy 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B17/00—Insoles for insertion, e.g. footbeds or inlays, for attachment to the shoe after the upper has been joined
- A43B17/02—Insoles for insertion, e.g. footbeds or inlays, for attachment to the shoe after the upper has been joined wedge-like or resilient
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B7/00—Footwear with health or hygienic arrangements
- A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
- A43B7/24—Insertions or other supports preventing the foot canting to one side , preventing supination or pronation
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B13/00—Soles; Sole-and-heel integral units
- A43B13/14—Soles; Sole-and-heel integral units characterised by the constructive form
- A43B13/18—Resilient soles
- A43B13/181—Resiliency achieved by the structure of the sole
- A43B13/186—Differential cushioning region, e.g. cushioning located under the ball of the foot
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B13/00—Soles; Sole-and-heel integral units
- A43B13/14—Soles; Sole-and-heel integral units characterised by the constructive form
- A43B13/18—Resilient soles
- A43B13/187—Resiliency achieved by the features of the material, e.g. foam, non liquid materials
- A43B13/188—Differential cushioning regions
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B13/00—Soles; Sole-and-heel integral units
- A43B13/14—Soles; Sole-and-heel integral units characterised by the constructive form
- A43B13/18—Resilient soles
- A43B13/189—Resilient soles filled with a non-compressible fluid, e.g. gel, water
-
- A—HUMAN NECESSITIES
- A43—FOOTWEAR
- A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
- A43B7/00—Footwear with health or hygienic arrangements
- A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
- A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
- A43B7/1455—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties
- A43B7/146—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties provided with acupressure points or means for foot massage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/01—Orthopaedic devices, e.g. splints, casts or braces
- A61F5/14—Special medical insertions for shoes for flat-feet, club-feet or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H7/00—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
- A61H7/001—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for without substantial movement between the skin and the device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/16—Physical interface with patient
- A61H2201/1683—Surface of interface
- A61H2201/169—Physical characteristics of the surface, e.g. material, relief, texture or indicia
- A61H2201/1695—Enhanced pressure effect, e.g. substantially sharp projections, needles or pyramids
Definitions
- the present invention is directed towards an apparatus for enhancing proprioception in the foot of a subject.
- Proprioception is a sense that informs the human body about the stability of individual joints and the body as a whole. Elderly people lose sufficient sense of proprioception which leads to loss of balance, stumbling, falls and accidents. Similar symptoms can be observed in the long-term ill and immobile. By increasing the proprioception of a subject, it has been shown that the number of falls experienced by the subject can be significantly reduced.
- a key source of information for the body's proprioceptive sense is the plantar surface of the foot.
- the plantar surface is the surface of the foot that faces downwards when a subject is standing with both feet flat on the floor.
- the body determines the position of the foot and the general orientation of the lower limbs based, in part, upon information received from the plantar surfaces of the feet. In the elderly or infirm, the ability of the body to properly process this information and maintain a proper orientation of the body is reduced.
- Pronation is the flattening out of the arch of the foot when the foot strikes the ground. Normally, the foot will pronate in order to absorb shock when the heel hits the ground, and to assist in balance during mid-stance. During pronation the ankle will tip towards the medial side.
- Excessive pronation can be problematic because the shifting causes increased stress on the medial side of the foot. Excessive pronation pulls on the stabilising muscles in the lower leg and often causes the knee to shift to the inside. This may cause the body to overcompensate and shift the ankle towards the lateral side causing the ankle to roll over. This can result in a stumble or a fall, possibly with resultant injuries to the subject.
- US 6, 237, 256 discloses a balance-enhancing insert for footwear.
- the document is concerned with treating the loss of cutaneous sensation in the sole of the feet, in particular as a result of old age.
- the document describes a shoe sole that stimulates a response in the perimeter of the subject's foot, as a shift in weight and balance occurs. This is achieved using ridges or protrusions in the sole of the shoe in order to stimulate the feeling in the foot of the subject.
- This device features ridges or protrusions only around the perimeter of the sole.
- the protrusions feature no differential of height, nor do they target specific areas of the foot.
- US 2497937 discloses a non slip insole base.
- the insoles comprises a moulded pattern on the bottom, shoe contacting, surface. This pattern simply stops the insole from sliding about within the shoe of a wearer, and provides not further benefits than an insole of conventional design.
- the insole comprises nothing to specifically contact and interact with the foot of the user.
- US 6237256 comprises a balance-enhanced insert for footwear having means for stimulating the plantar surface of the foot of a user.
- the means for stimulating the plantar surface of the foot only feature around the perimeter of the insert. Although this may help proprioception, it may not be sufficient enough to treat people with severe proprioception difficulties.
- US 4694831 discloses a massage footwear having protrusions thereon.
- the protrusions on the insert are designed to provide a massaging action to a user when they are walking.
- the protrusions are not placed so as to increase proprioception.
- US 5704137 provides a shoe having a hydrodynamic pad.
- the pad uses an inner bladder to create a protrusion on the outer perimeter of the device when in use. Again, the effect only occurs on the outer perimeter of the device and the device does not cover a substantial portion of the plantar surface of the foot.
- WO 2006/056931 provides an insert for proprioceptive and reflexology stimulation.
- the insert comprises a plurality of stimulation members that both act to stimulate the foot of the user and deform under the action of the user.
- the present invention provides an apparatus for enhancing proprioception in the plantar surface of the foot without causing the brain to adapt to, and thus ignore, the enhanced signal from the nerve endings of the plantar surface.
- an apparatus for enhancing proprioception in the foot of a subject comprising: a member having a surface for contacting the sole of the foot of the subject; and structures disposed on the surface of the member for applying increased pressure to a region of the subjects foot whilst in use, thereby increasing the proprioception of the subject.
- the apparatus may be incorporated into a form of footwear, for example, the apparatus may be used to form the actual sole of the footwear, or be incorporated into the sole of the footwear in some way.
- the apparatus may also be in the form of an insole, for insertion into the chosen footwear of the subject.
- the apparatus is manufactured from a suitable material that is flexible enough so as to allow a large area of contact with the plantar surface, whilst maintaining the ability to support the plantar surface.
- the material may be a gel-type material, preferably of the silicone gel variety, or may be manufactured from a polyurethane (PU), which may, or may not be filled in order to provide the flexibility required, so as to not cause aggravation to any area of the plantar surface.
- PU polyurethane
- the apparatus may further comprise a fascial groove.
- the groove features on the apparatus where the fascial tendon meets the upper surface of the apparatus.
- the groove allows the soft tissues of the plantar surface to move during normal motion of the foot, so that the orthosis does not impede the normal walking action of the subject.
- the enhanced proprioception claimed by the current invention is achieved by specific positioning of the aforementioned structures.
- the structures are placed within various dermatomes of the plantar surface.
- a dermatome is an area of skin innervated by sensory fibres from a single spinal nerve. By targeting certain nerve endings in the plantar surface in this way, it is possible to enhance the proprioception of the subject.
- the dermatomes this apparatus is concerned with include, but are not limited to, the saphenous/medial plantar, this is located on the inner area of the plantar surface, near the big toe, the sural/lateral plantar, this is located on the outer area of the plantar surface, near the little toe, and the calcaneal, this is the area surrounding the bottom of the heel.
- the structures may have any suitable form to provide the required stimulation of the nerve endings in the foot of the user, but without providing the user with undue discomfort or pain.
- the structures may take the form of raised portions of the surface of the member.
- the raised portions may have any suitable shape, for example being rounder, hemispherical, and/or angular protrusions, such as rectangular slabs or conical or pyramidal protusions.
- the structures may be the same or of different height, according to their position on the member.
- the structures may be arranged in any suitable pattern, for example randomly, such as in the form of random slabs, a single line or a plurality of lines.
- the structures may have the form of recesses in the surface of the member. Again, the recesses may have any suitable form, such as rounded, hemispherical, angular, pyramidal, conical and the like.
- the member may comprise a single form of structure of a mixture of two or more of the aforementioned structures.
- the proprioception of the subject will be enhanced by the structures mentioned above.
- the structures may feature at different heights over the surface of the member within the previously specified dermatomes in order to stimulate the various nerve endings with the purpose of enhancing proprioception of the subject.
- the different heights provide a variable surface for contact with the foot.
- the structures provide an overall uniform effect on the foot of the user, and the proprioception of the subject will be enhanced because of the difference in height of the structures.
- the structures are preferably disposed on the member so as to have the effect of feeling different to the user, depending on whether the foot is undergoing pronation (the inward roll of the foot), supination (the opposite of pronation, where the foot does not roll inwards enough), inversion (turning the foot laterally, so the plantar surface faces inwards), or eversion (turning the foot laterally, so the plantar surface faces outwards).
- pronation the inward roll of the foot
- supination the opposite of pronation, where the foot does not roll inwards enough
- inversion turning the foot laterally, so the plantar surface faces inwards
- eversion turning the foot laterally, so the plantar surface faces outwards.
- the apparatus extends under the calcaneus of the foot; this is the quadrangular bone at the back of the tarsus, also known as the heel bone.
- the apparatus fits under the calcaneus and provides support for this bone by filling the space beneath it.
- the calcaneus is covered with a fat pad, commonly referred to as the heel.
- the apparatus preferably comprises means for cushioning the calcaneus.
- the structures are preferably sufficiently rigid as not to substantially deform under the weight or action of the foot of the user, for example when standing or walking. In this way, with rigid structures, the enhancement of the proprioception of the user is not diminished or lost in times of activity or when the user applies significant force through their feet.
- Figure 1 is a representation of the apparatus for use with the left foot.
- Figure 2 is a cross-sectional view of the apparatus in use.
- Figures 3a , 3b and 3c are representations of the apparatus for use with the left foot showing the cones, randomly angled slab protrusions and circular recesses respectively.
- FIG. 1 there is shown an embodiment of the apparatus for enhancing proprioception of a subject, generally indicated as 2.
- the big toe 4 and the little toe 6, shown so as to give an indication of where the dermatomes lie on the plantar surface of the foot.
- the present invention does not extend under the toes.
- the area 8 under the big toe 6 is the saphenous zone.
- the area adjacent to this is the medial plantar dermatome 9.
- the area 10, under the little toe 6, is the sural dermatome.
- the lateral plantar dermatome 11 is adjacent to both the medial plantar and sural dermatomes.
- the area 12, between areas 8 and 9, is the plantar fascial groove.
- the area 14 is the calcaneal dermatome.
- the hole 16 features beneath the calcaneus, which is filled with a softer material than that that makes up the body of the apparatus.
- FIG. 2 there is shown a cross-sectional representation of the bones of the foot and lower leg.
- the tibia 102 and fibula 104 connect with the talus 106.
- the talus 106 then connects with the calcaneus 108.
- the edge of the calcaneus is supported by the apparatus 110, as shown in the diagram.
- the apparatus 110 fills the gap that would otherwise feature at the side of the calcaneus, thus the apparatus provides the calcaneus with support.
- FIG. 3a there is shown an embodiment of the apparatus for enhancing proprioception of a subject, generally indicated as 2.
- the protrusions in Figure 3a are in the form of cones, disposed in the region of the apparatus corresponding to the saphenous zone 8, the medial plantar dermatome 9, and the sural dermatome 10 of the foot of the subject.
- the cones are shown as being of substantially the same height and dimensions. However, it is to be understood that the cones may differ in size, in particular height, across one or more of the zones.
- Figure 3b shows a similar arrangement to that of Figure 3a, with the cones replaced by randomly angled slabs in the aforementioned regions. Again, the size and height of the slabs may be varied across the apparatus to achieve the desired enhancement of proprioception in the subject.
- Figure 3c shows a similar arrangement to that of Figures 3a and 3b, with the cones and slabs being replaced by recesses or dimples in the surface of the member. The size and depth of the recesses may be varied within one region or zone, or across several different zones, as required.
- the apparatus is flexible enough so as to easily mould to the sole of the shoe of the subject, and also the plantar surface of the foot.
- the apparatus may come in different sizes in order to fit the foot of the subject, or it may be manufactured in a limited number of sizes, or even only one size, which can then by trimmed to fit the foot of the subject as desired.
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nursing (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0705092A GB2447644B (en) | 2007-03-16 | 2007-03-16 | Foot orthosis apparatus |
PCT/GB2008/000920 WO2008113988A1 (fr) | 2007-03-16 | 2008-03-14 | Appareil de type orthèse de pied |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2136761A1 true EP2136761A1 (fr) | 2009-12-30 |
Family
ID=38008567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08718760A Withdrawn EP2136761A1 (fr) | 2007-03-16 | 2008-03-14 | Appareil de type orthèse de pied |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2136761A1 (fr) |
GB (1) | GB2447644B (fr) |
WO (1) | WO2008113988A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2496186A (en) * | 2011-11-07 | 2013-05-08 | Terra Plana Internat Ltd | An item of footwear to remind a wearer to walk with a correct loading pattern |
GB2497340B (en) * | 2011-12-08 | 2014-12-31 | Footjacks Ltd | Footwear/insole for footwear |
US20180243166A1 (en) | 2017-02-24 | 2018-08-30 | Naboso Technology, LLC | Proprioceptor Stimulation Material |
DE102018009107A1 (de) * | 2018-11-21 | 2020-05-28 | Jörg Hefft | Vorrichtung zur Stimulation von Faszien |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006056931A1 (fr) * | 2004-11-23 | 2006-06-01 | Ks Italia S.A.S. Di Ambrosone Mario & C. | Dispositif plantaire pour stimulation proprioceptive, exteroceptive, pressoceptive et/ou reflexogene verticale |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694831A (en) * | 1984-01-04 | 1987-09-22 | Seltzer Charles J | Massage footwear |
US4897937A (en) * | 1987-09-23 | 1990-02-06 | Colgate-Palmolive Company | Non-slip insole base |
US5551173A (en) * | 1995-03-16 | 1996-09-03 | Chambers; Mark D. | Comfort insole |
US5704137A (en) * | 1995-12-22 | 1998-01-06 | Brooks Sports, Inc. | Shoe having hydrodynamic pad |
US6237256B1 (en) * | 1998-08-12 | 2001-05-29 | Sunnybrook And Women's College Health Sciences Centre | Balance-enhanced insert for footwear |
DE50101077D1 (de) * | 2001-03-26 | 2004-01-15 | Vitaflex Dr Walter Mauch Gmbh | Innensohle für Schuhe |
US7250033B2 (en) * | 2003-09-03 | 2007-07-31 | Beiruti Ahmad M | Flexing multiple function interactive massage and reflexology unit |
US7584556B2 (en) * | 2005-01-26 | 2009-09-08 | Foot Techno, Inc. | Footgear and insole |
DE202006002484U1 (de) * | 2006-02-15 | 2006-06-29 | Ofa Bamberg Gmbh | Einlegesohle und orthopädischer Schuh hierfür |
-
2007
- 2007-03-16 GB GB0705092A patent/GB2447644B/en not_active Expired - Fee Related
-
2008
- 2008-03-14 WO PCT/GB2008/000920 patent/WO2008113988A1/fr active Application Filing
- 2008-03-14 EP EP08718760A patent/EP2136761A1/fr not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006056931A1 (fr) * | 2004-11-23 | 2006-06-01 | Ks Italia S.A.S. Di Ambrosone Mario & C. | Dispositif plantaire pour stimulation proprioceptive, exteroceptive, pressoceptive et/ou reflexogene verticale |
Also Published As
Publication number | Publication date |
---|---|
GB2447644B (en) | 2010-04-28 |
GB2447644A (en) | 2008-09-24 |
WO2008113988A1 (fr) | 2008-09-25 |
GB0705092D0 (en) | 2007-04-25 |
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