EP2108452A1 - Support de puce réglable - Google Patents
Support de puce réglable Download PDFInfo
- Publication number
- EP2108452A1 EP2108452A1 EP08006714A EP08006714A EP2108452A1 EP 2108452 A1 EP2108452 A1 EP 2108452A1 EP 08006714 A EP08006714 A EP 08006714A EP 08006714 A EP08006714 A EP 08006714A EP 2108452 A1 EP2108452 A1 EP 2108452A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- microchip
- holder
- interconnection
- rail
- holder according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
Definitions
- This invention in general, relates to the field of micro systems.
- the present invention provides an adjustable chip holder for microchips with varying positions of the connecting ports.
- miniaturization Since the first integrated circuit was invented, miniaturization has become an important research topic in both electronic and non-electronic devices. In the late 1970s, miniaturization was extended to mechanical devices with electronics which is now known as microelectromechanical systems (MEMS). MEMS research has been largely encouraged by the first introduction of miniaturized total analysis systems, and MEMS systems are widely employed in areas from biomedical and drug delivery to space and fuel cell microfluidic systems. These systems have been reduced in size to micro scale for the realization of fully integrated micro systems such as lab-on-a-chip or a micro total analysis system. Major advantages of miniaturization are the drastic decrease in chemical reaction time and less consumption of expensive chemical reagents as well as enhancement of reliability.
- microfluidic systems are expensive to realize in a chip or analysis system, it is essential that the functionality is as desired. It is therefore required that the systems are thoroughly tested prior to the final miniaturization. Microfluidic systems are therefore well-suited in an experiential setting or in the context of research.
- microchips used e.g. for analyzing fluidic samples or process electronic data. These microchips are normally connected to external devices through chip holders.
- microchips comprise connection points on one side of the chip. Such connection points can be fluidic, electrical or the like.
- the chips are connected to the external devices by e.g. gluing tubes directly on the connection points of the chip. As this must be done with accuracy, this is a very time-consuming process.
- the microchip wires are soldered on the ports. A more time-economic possibility is to make custom made holders for specific microchips. These microchip holders are provided with elements onto which the microchip is pressed to achieve a connection.
- microchip holder so single-time used microchips can be used and that this setting can be standardized. Since microchips vary in e.g. size, number and position of connection points, individual microchip holders have a limited scope of use. Consequently, for each type of microchip a new holder must be fabricated which from the viewpoint of costs and usability is problematic.
- the objective of the present invention is to solve the above-mentioned problems.
- the microchip holder for holding a microchip comprises at least one interconnection point for interconnecting at least one connection point on the microchip with at least one external device.
- the microchip holder further comprises means for adjusting the position of the interconnection point, enabling the interconnection points to be adjusted to fit the position of the connection points on the microchip.
- the microchip holder is advantageous as it provides a reliable connection between microchips and external devices in microfluidic, microelectrical and microoptical systems.
- the highly configurable microchip holder can be used many times as it can be (re)adjusted to fit any microchip varying in both size, position of connection points and purpose.
- the microchip holder of the present invention eliminates the need for special skills and reduces the time needed to build micro systems. Consequently, the costs of configuring micro systems are reduced considerably.
- the microchip holder is therefore well suited in research and educational settings.
- the interconnection points are adjustable in a first direction using a rail system comprising at least one rail, the rail having at least one interconnection point adjustable in the direction of the rail.
- the rail is adjustable in a second direction.
- the first direction and said second direction of the microchip holder corresponds to an x and a y axis in a two-dimensional co-ordinate system.
- rail comprised in the microchip holder comprises an elongated hole and the interconnection point comprises a collet positioned in said hole adapted to be adjusted in the direction of said elongated hole.
- the adjustment mechanism is advantageous as it is very easy to operate.
- the interconnection points comprised in the microchip holder are adapted to interconnect the connection point of the microchip and the external devices with a transport channel for enabling the transport of a fluid between the microchip and the external device.
- the interconnection point of the microchip holder comprises a sealing element for sealing the connection between the interconnection point and the connection point on the microchip.
- the sealing element is an elastic pad.
- the microchip further comprises a cover for pressing the microchip and thereby the connection point towards the interconnection points in the microchip holder.
- the microchip holder comprises a suction device for sucking the microchip and thereby the connection point towards the interconnection points in the microchip holder.
- the microchip holder comprises a surface part for positioning the microchip, wherein the surface part comprises at least one interconnection point.
- the microchip holder comprises a frame surrounding the microchip and corresponding to the dimensions of the microchip, wherein the frame comprises at least one interconnection point.
- the microchip holder comprises means for adjusting the size of the frame enabling the holder to fit the dimension of different microchips. This is advantageous as the microchip holder can accommodate a great variety of dimensions of the microchips.
- FIG 1 illustrates a rail system 100 comprised in an adjustable chip holder for holding a microchip in accordance with one embodiment of the present invention.
- the rail system 100 comprises an elongated hole 104 comprising a collet 102 arranged in the hole 104 for adjusting the position of the collet 102 in the direction of the elongated hole 104.
- An interconnection element 103 is comprised by the collet 102 and is, as stated, free to move in the elongated hole 104.
- the interconnection element 103 enables a connection to the connecting points of a microchip.
- the rail system 100 further comprises two side holes 105a, 105b to position the rail 101 in a second direction in the adjustable chip holder (not shown).
- the rail movement in this second direction enables a movement of the interconnecting element 103 to a specific position required by the connection points of the microchip.
- the rail 101 can be aligned in directions corresponding to an x-axis and a y-axis.
- the interconnection element 103 can further be connected to external devices, through e.g. a wire or tube, to connect the microchip to these external devices (not shown).
- the interconnection elements 103 can be made of e.g. a flexible and/or elastomeric and/or polymeric material, enabling a sealed connection to the connection points of a microfluidic chip.
- the connection elements 103 can have different shapes such as circular or elliptical.
- the interconnection elements 103 could be an interface for establishing an electrical connection to a microelectrical chip.
- the interconnection elements 103 could be an interface for establishing an optical connection to a microoptical chip.
- FIG 2 illustrates a perspective view of an adjustable microchip holder 200 according to the present invention.
- the microchip holder 200 comprises a number of rail systems 100 as described in figure 1 .
- the chip holder 200 enables a connection between a microchip and external devices such as sensors, actuators, fluid pipes or control devices, etc.
- the microchip holder 200 comprises a frame 207, wherein two rods 202 are arranged parallel to each other in opposite sides of the frame 207.
- the rods 202 extend through the two sides holes 105a and 105b of the rail system 100.
- Each rail system 100 can be moved along the longitudinal axis of the two rods 202.
- the collet 102 and the comprised interconnection element 103 can, as described in figure 1 , be moved in a direction along the elongated hole 104, whereby the interconnection element 103 can be moved in a two-dimensional plane given by the rail system 100 and the rods 202.
- the microchip holder 200 can be adapted to the characteristics of a microchip, i.e. the interconnection elements 103 can be adjusted to the position of the connection points of a microchip, whereby a connection between the microchip and external devices can be obtained.
- the microchip (not shown) is placed on the surface part constituted by the plane of the interconnection elements 103.
- the microchip can rest on the interconnection elements 103 and be supported by the sides of the hole (not indicated) in the top of the frame 207.
- the microchip holder 200 can simply be (re)adjusted to fit another microchip with different positions of the connection points.
- the rail system 100 could be guided in or by other rail(s) or rods placed at e.g. the top, side or bottom of the microchip holder 200, or alternatively a combination of these embodiments.
- the hole (not indicated) in the top of the frame 207 of the microchip holder 200, wherein the microchip is placed can be adjusted to fit different sizes of microchips.
- Figure 3 illustrates an exploded perspective of a microchip holder system 300, where a microchip 301 is inserted into the chip holder 200 and pressed against the surface part constituted by the connection elements 103 with a cover 302, whereby a connection between the microchip and external devices is obtained.
- the microchip holder 200 can be adjusted to the individual characteristics of a microchip as described in figure 2 .
- the position of the cover is fixed by the male/female connection between the protrusions 206a-d of the holder 201 and the holes or indentations 306a-d of the cover 302.
- the cover 302 can further be fixed to the frame 201 using screws, threaded bolts in combination with nuts or durable and/or replaceable snap functions.
- the microchip 301 can also be pressed against the chip holder 200 by other means, such as e.g. a suction device.
- Figure 4 illustrates a perspective view of a chip holder 200 comprising a frame 207 and interconnection elements 103 for connecting to a microchip with connection points on the side of the microchip (not shown).
- the frame 207 comprises a rail 104 in which the interconnection elements 103 are arranged.
- the interconnection elements 103 are comprised by a collet (not indicated) resembling the collet 102 disclosed in figure 2 .
- the interconnection elements 103 can be moved along the rail 104 and thereby placed in a position corresponding to the connection points of a microchip (not shown).
- the frame 207 further comprises an opening (not indicated) along the inner side of the frame 207 facing the center of the chip holder 200 and is embodied in connection to the rail 104.
- the microchip By sliding the microchip (not shown) into this opening, the microchip is aligned and fixed in the holder 200.
- a connection between the microchip and external devices can hereby be obtained.
- the microchip can simply be removed by pulling it out of the openings of the frame 207.
- the chip holder 200 could also comprise interconnection elements 103 in the bottom of the frame 207 as e.g. disclosed in figure 2 . This would enable a connection between external devices and a microchip comprising connecting points at the bottom and side of the microchip.
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08006714A EP2108452A1 (fr) | 2008-04-02 | 2008-04-02 | Support de puce réglable |
PCT/DK2009/000081 WO2009121363A1 (fr) | 2008-04-02 | 2009-04-02 | Porte-puce ajustable |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08006714A EP2108452A1 (fr) | 2008-04-02 | 2008-04-02 | Support de puce réglable |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2108452A1 true EP2108452A1 (fr) | 2009-10-14 |
Family
ID=39642652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08006714A Withdrawn EP2108452A1 (fr) | 2008-04-02 | 2008-04-02 | Support de puce réglable |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2108452A1 (fr) |
WO (1) | WO2009121363A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103878038B (zh) * | 2012-12-19 | 2015-09-09 | 中国科学院大连化学物理研究所 | 一种通用型微流控芯片夹具 |
KR102310344B1 (ko) * | 2020-06-08 | 2021-10-07 | 주식회사 에스엔씨솔루션 | 반도체칩 범용홀더 |
CN113019490B (zh) * | 2021-03-05 | 2024-06-07 | 苏州工业职业技术学院 | 一种可微调节的微控流芯片固定夹具 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0753748A2 (fr) * | 1995-07-14 | 1997-01-15 | Ciba Corning Diagnostics Corp. | Dispositif de transport d'échantillons |
EP1186891A1 (fr) * | 2000-09-05 | 2002-03-13 | Tecan Schweiz AG | Support pour plaque de microtitrage |
EP1652583A1 (fr) * | 2004-11-02 | 2006-05-03 | Sysmex Corporation | Portoir pour cones de pipette |
EP1742064A2 (fr) * | 2005-07-06 | 2007-01-10 | Genetix Limited | Procédés et appareil d'imagerie et de traitement d'échantillons dans les conteneurs d'échantillons biologiques |
WO2007043561A1 (fr) * | 2005-10-13 | 2007-04-19 | Tokai Hit Co., Ltd. | Platine porte-objet et corps de microscope |
EP1898219A2 (fr) * | 2006-09-07 | 2008-03-12 | Ushiodenki Kabushiki Kaisha | Dispositif de test à micropuces |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7422725B2 (en) * | 2003-05-01 | 2008-09-09 | Enplas Corporation | Sample handling unit applicable to microchip, and microfluidic device having microchips |
ATE462493T1 (de) * | 2004-02-02 | 2010-04-15 | Silicon Valley Scient Inc | Integriertes system mit modularen mikrofluidischen komponenten |
-
2008
- 2008-04-02 EP EP08006714A patent/EP2108452A1/fr not_active Withdrawn
-
2009
- 2009-04-02 WO PCT/DK2009/000081 patent/WO2009121363A1/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0753748A2 (fr) * | 1995-07-14 | 1997-01-15 | Ciba Corning Diagnostics Corp. | Dispositif de transport d'échantillons |
EP1186891A1 (fr) * | 2000-09-05 | 2002-03-13 | Tecan Schweiz AG | Support pour plaque de microtitrage |
EP1652583A1 (fr) * | 2004-11-02 | 2006-05-03 | Sysmex Corporation | Portoir pour cones de pipette |
EP1742064A2 (fr) * | 2005-07-06 | 2007-01-10 | Genetix Limited | Procédés et appareil d'imagerie et de traitement d'échantillons dans les conteneurs d'échantillons biologiques |
WO2007043561A1 (fr) * | 2005-10-13 | 2007-04-19 | Tokai Hit Co., Ltd. | Platine porte-objet et corps de microscope |
EP1898219A2 (fr) * | 2006-09-07 | 2008-03-12 | Ushiodenki Kabushiki Kaisha | Dispositif de test à micropuces |
Also Published As
Publication number | Publication date |
---|---|
WO2009121363A1 (fr) | 2009-10-08 |
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Effective date: 20100415 |