EP2068628A4 - Procédé de traitement d'une affection associée a la phosphorylation de task-i - Google Patents

Procédé de traitement d'une affection associée a la phosphorylation de task-i

Info

Publication number
EP2068628A4
EP2068628A4 EP07836321A EP07836321A EP2068628A4 EP 2068628 A4 EP2068628 A4 EP 2068628A4 EP 07836321 A EP07836321 A EP 07836321A EP 07836321 A EP07836321 A EP 07836321A EP 2068628 A4 EP2068628 A4 EP 2068628A4
Authority
EP
European Patent Office
Prior art keywords
phosphorylation
task
treating
condition associated
condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07836321A
Other languages
German (de)
English (en)
Other versions
EP2068628A2 (fr
Inventor
Steven J Feinmark
Richard B Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2006/029544 external-priority patent/WO2007014347A2/fr
Priority claimed from US11/498,343 external-priority patent/US8097650B2/en
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of EP2068628A2 publication Critical patent/EP2068628A2/fr
Publication of EP2068628A4 publication Critical patent/EP2068628A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP07836321A 2006-07-27 2007-07-27 Procédé de traitement d'une affection associée a la phosphorylation de task-i Withdrawn EP2068628A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2006/029544 WO2007014347A2 (fr) 2005-07-27 2006-07-27 Methode de traitement d'etats pathologiques associes a la phosphorylation du canal task-1
US11/498,343 US8097650B2 (en) 2005-07-27 2006-08-02 Method of treating a condition associated with phosphorylation of TASK-1
PCT/US2007/016999 WO2008013988A2 (fr) 2006-07-27 2007-07-27 Procédé de traitement d'une affection associée a la phosphorylation de task-i

Publications (2)

Publication Number Publication Date
EP2068628A2 EP2068628A2 (fr) 2009-06-17
EP2068628A4 true EP2068628A4 (fr) 2009-11-04

Family

ID=38982134

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07836321A Withdrawn EP2068628A4 (fr) 2006-07-27 2007-07-27 Procédé de traitement d'une affection associée a la phosphorylation de task-i

Country Status (2)

Country Link
EP (1) EP2068628A4 (fr)
WO (1) WO2008013988A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001097798A1 (fr) * 2000-06-16 2001-12-27 Smithkline Beecham Corporation Procede servant a prevenir ou a reduire des evenements cardio-vasculaires induits par intervention coronarienne
DE10332685A1 (de) * 2003-07-18 2005-02-17 Bayer Healthcare Ag Vorhof-selektiv exprimierte Kaliumkanäle
WO2007014347A2 (fr) * 2005-07-27 2007-02-01 The Trustees Of Columbia University In The City Of New York Methode de traitement d'etats pathologiques associes a la phosphorylation du canal task-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1051485A1 (fr) * 1998-01-27 2000-11-15 Smithkline Beecham Plc Canal potassium a deux pores semblable a trek-1

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001097798A1 (fr) * 2000-06-16 2001-12-27 Smithkline Beecham Corporation Procede servant a prevenir ou a reduire des evenements cardio-vasculaires induits par intervention coronarienne
DE10332685A1 (de) * 2003-07-18 2005-02-17 Bayer Healthcare Ag Vorhof-selektiv exprimierte Kaliumkanäle
WO2007014347A2 (fr) * 2005-07-27 2007-02-01 The Trustees Of Columbia University In The City Of New York Methode de traitement d'etats pathologiques associes a la phosphorylation du canal task-1

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OGITA H ET AL: "Synthesis and structure-activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 11, no. 4, 26 February 2001 (2001-02-26), pages 549 - 551, XP004230056, ISSN: 0960-894X *

Also Published As

Publication number Publication date
WO2008013988A9 (fr) 2008-04-10
EP2068628A2 (fr) 2009-06-17
WO2008013988A3 (fr) 2008-12-18
WO2008013988A2 (fr) 2008-01-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20090225

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

A4 Supplementary search report drawn up and despatched

Effective date: 20091007

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 9/06 20060101ALI20091001BHEP

Ipc: A61K 31/196 20060101ALI20091001BHEP

Ipc: A61K 31/192 20060101ALI20091001BHEP

Ipc: A61K 31/167 20060101ALI20091001BHEP

Ipc: A61K 31/10 20060101ALI20091001BHEP

Ipc: A61K 31/16 20060101ALI20091001BHEP

Ipc: A01N 37/18 20060101AFI20090303BHEP

17Q First examination report despatched

Effective date: 20100115

STAA Information on the status of an ep patent application or granted ep patent

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18W Application withdrawn

Effective date: 20140407