EP2068628A4 - Method of treating a condition associated with phosphorylation of task-1 - Google Patents
Method of treating a condition associated with phosphorylation of task-1Info
- Publication number
- EP2068628A4 EP2068628A4 EP07836321A EP07836321A EP2068628A4 EP 2068628 A4 EP2068628 A4 EP 2068628A4 EP 07836321 A EP07836321 A EP 07836321A EP 07836321 A EP07836321 A EP 07836321A EP 2068628 A4 EP2068628 A4 EP 2068628A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- phosphorylation
- task
- treating
- condition associated
- condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title 1
- 230000026731 phosphorylation Effects 0.000 title 1
- 238000006366 phosphorylation reaction Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2006/029544 WO2007014347A2 (en) | 2005-07-27 | 2006-07-27 | Method of treating a condition associated with phosphorylation of task-1 |
US11/498,343 US8097650B2 (en) | 2005-07-27 | 2006-08-02 | Method of treating a condition associated with phosphorylation of TASK-1 |
PCT/US2007/016999 WO2008013988A2 (en) | 2006-07-27 | 2007-07-27 | Method of treating a condition associated with phosphorylation of task-1 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2068628A2 EP2068628A2 (en) | 2009-06-17 |
EP2068628A4 true EP2068628A4 (en) | 2009-11-04 |
Family
ID=38982134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07836321A Withdrawn EP2068628A4 (en) | 2006-07-27 | 2007-07-27 | Method of treating a condition associated with phosphorylation of task-1 |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2068628A4 (en) |
WO (1) | WO2008013988A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001097798A1 (en) * | 2000-06-16 | 2001-12-27 | Smithkline Beecham Corporation | Method for the prevention or reduction of cardiovascular events associated with coronary intervention |
DE10332685A1 (en) * | 2003-07-18 | 2005-02-17 | Bayer Healthcare Ag | Use of a modulator of specific potassium channels, expressed preferentially in the atrium, for treatment and prevention of arrhythmia, coronary disease and hypertension |
WO2007014347A2 (en) * | 2005-07-27 | 2007-02-01 | The Trustees Of Columbia University In The City Of New York | Method of treating a condition associated with phosphorylation of task-1 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999037762A1 (en) * | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Trek-1 like two pore potassium channel |
-
2007
- 2007-07-27 WO PCT/US2007/016999 patent/WO2008013988A2/en active Application Filing
- 2007-07-27 EP EP07836321A patent/EP2068628A4/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001097798A1 (en) * | 2000-06-16 | 2001-12-27 | Smithkline Beecham Corporation | Method for the prevention or reduction of cardiovascular events associated with coronary intervention |
DE10332685A1 (en) * | 2003-07-18 | 2005-02-17 | Bayer Healthcare Ag | Use of a modulator of specific potassium channels, expressed preferentially in the atrium, for treatment and prevention of arrhythmia, coronary disease and hypertension |
WO2007014347A2 (en) * | 2005-07-27 | 2007-02-01 | The Trustees Of Columbia University In The City Of New York | Method of treating a condition associated with phosphorylation of task-1 |
Non-Patent Citations (1)
Title |
---|
OGITA H ET AL: "Synthesis and structure-activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, vol. 11, no. 4, 26 February 2001 (2001-02-26), pages 549 - 551, XP004230056, ISSN: 0960-894X * |
Also Published As
Publication number | Publication date |
---|---|
EP2068628A2 (en) | 2009-06-17 |
WO2008013988A2 (en) | 2008-01-31 |
WO2008013988A3 (en) | 2008-12-18 |
WO2008013988A9 (en) | 2008-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090225 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20091007 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 9/06 20060101ALI20091001BHEP Ipc: A61K 31/196 20060101ALI20091001BHEP Ipc: A61K 31/192 20060101ALI20091001BHEP Ipc: A61K 31/167 20060101ALI20091001BHEP Ipc: A61K 31/10 20060101ALI20091001BHEP Ipc: A61K 31/16 20060101ALI20091001BHEP Ipc: A01N 37/18 20060101AFI20090303BHEP |
|
17Q | First examination report despatched |
Effective date: 20100115 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Effective date: 20140407 |