EP2061466A4 - Composés à base de quinoléine et de naphtyridine à substitution thio en position 4 - Google Patents
Composés à base de quinoléine et de naphtyridine à substitution thio en position 4Info
- Publication number
- EP2061466A4 EP2061466A4 EP07837234A EP07837234A EP2061466A4 EP 2061466 A4 EP2061466 A4 EP 2061466A4 EP 07837234 A EP07837234 A EP 07837234A EP 07837234 A EP07837234 A EP 07837234A EP 2061466 A4 EP2061466 A4 EP 2061466A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- substituted quinoline
- thio substituted
- naphthyridine compounds
- naphthyridine
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83992206P | 2006-08-23 | 2006-08-23 | |
PCT/US2007/018607 WO2008024423A2 (fr) | 2006-08-23 | 2007-08-22 | Composés à base de quinoléine et de naphtyridine à substitution thio en position 4 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2061466A2 EP2061466A2 (fr) | 2009-05-27 |
EP2061466A4 true EP2061466A4 (fr) | 2010-12-29 |
Family
ID=39107397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07837234A Withdrawn EP2061466A4 (fr) | 2006-08-23 | 2007-08-22 | Composés à base de quinoléine et de naphtyridine à substitution thio en position 4 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP2061466A4 (fr) |
JP (1) | JP2010501570A (fr) |
AU (1) | AU2007288188A1 (fr) |
CA (1) | CA2677001A1 (fr) |
WO (1) | WO2008024423A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6740354B2 (ja) | 2015-10-05 | 2020-08-12 | ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク | オートファジーの流れ及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法 |
KR20210060556A (ko) | 2018-09-18 | 2021-05-26 | 니캉 테라퓨틱스 인코포레이티드 | Src 호몰로지-2 포스파타아제 억제제로서의 3-치환된 헤테로아릴 유도체 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015820A (en) * | 1995-07-31 | 2000-01-18 | Centre National De La Recherche Scientifique (Cnrs) | 4-Aryl-thio-pyridin-2(1H)-ones, medicines containing them and their uses in the treatment of illnesses linked to HIV |
WO2005012288A1 (fr) * | 2003-08-01 | 2005-02-10 | Genelabs Technologies, Inc | Derives de l'imidazole bicycliques diriges contre les flaviviridae |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992017452A1 (fr) * | 1991-04-03 | 1992-10-15 | Korea Research Institute Of Chemical Technology | Derives de 2-quinoleinone |
-
2007
- 2007-08-22 JP JP2009525625A patent/JP2010501570A/ja active Pending
- 2007-08-22 EP EP07837234A patent/EP2061466A4/fr not_active Withdrawn
- 2007-08-22 AU AU2007288188A patent/AU2007288188A1/en not_active Abandoned
- 2007-08-22 WO PCT/US2007/018607 patent/WO2008024423A2/fr active Application Filing
- 2007-08-22 CA CA002677001A patent/CA2677001A1/fr not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6015820A (en) * | 1995-07-31 | 2000-01-18 | Centre National De La Recherche Scientifique (Cnrs) | 4-Aryl-thio-pyridin-2(1H)-ones, medicines containing them and their uses in the treatment of illnesses linked to HIV |
WO2005012288A1 (fr) * | 2003-08-01 | 2005-02-10 | Genelabs Technologies, Inc | Derives de l'imidazole bicycliques diriges contre les flaviviridae |
Non-Patent Citations (3)
Title |
---|
EL-HOSSAIN ALI MOHAMED ET AL: "SYNTHESIS AND BEHAVIOUR OF 2,4-DICHLORO-6-METHYLQUINOLINE AND 4-CHLORO-6-METHYL-2(1H)QUINOLONE TOWARDS SOME NUCLEOPHILIC REAGENTS", JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, BELGRADE, YU, vol. 58, no. 10, 1 January 1993 (1993-01-01), pages 737 - 743, XP009056091, ISSN: 0352-5139 * |
MIREK J. ET AL: "Synthesis and pharmacological properties of some 7H-[1]-benzothiopyrano-[3,2-c]quinolin-7-ones", POL. J. PHARMACOL. PHARM., vol. 35, 1 January 1983 (1983-01-01), pages 139 - 149, XP002606763 * |
MOSTAFA M ISMAIL ET AL: "Chemistry of Substituted Quinolinones. Part VI. Synthesis and Nucleophilic Reactions of 4-Chloro-8-methylquinolin-2(1H)-one and its Thione An", MOLECULES, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL, BASEL, CH, vol. 5, no. 12, 1 January 2000 (2000-01-01), pages 1224 - 1239, XP009140312, ISSN: 1420-3049 * |
Also Published As
Publication number | Publication date |
---|---|
AU2007288188A1 (en) | 2008-02-28 |
EP2061466A2 (fr) | 2009-05-27 |
WO2008024423A3 (fr) | 2008-11-20 |
CA2677001A1 (fr) | 2008-02-28 |
WO2008024423A2 (fr) | 2008-02-28 |
JP2010501570A (ja) | 2010-01-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL193265A0 (en) | Quinoline derivatives | |
HK1208437A1 (en) | Antibacterial quinoline derivatives | |
EP1973884A4 (fr) | Nouveaux hétérocycles | |
IL186041A (en) | 7-Amino Alkylidanyl-heterocyclic quinolones and naphthyridones | |
HK1137441A1 (en) | Antibacterial quinoline derivatives | |
IL197301A0 (en) | Quinoline derivatives with 5-ht-binding properties | |
IL241548B (en) | Antibacterial quinoline derivatives | |
IL199084A0 (en) | Antibacterial quinoline derivatives | |
HK1137428A1 (en) | Antibacterial quinoline derivatives | |
EP2061466A4 (fr) | Composés à base de quinoléine et de naphtyridine à substitution thio en position 4 | |
HK1137437A1 (en) | Antibacterial quinoline derivatives | |
ZA200806877B (en) | Quinoline Derivatives | |
GB0610551D0 (en) | Quinoline compounds | |
GB0720667D0 (en) | quinolin-2-one compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090320 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
111L | Licence recorded |
Free format text: 0101 PRESIDIO PHARMACEUTICALS INC Effective date: 20090320 |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07D 215/36 20060101ALI20101115BHEP Ipc: A61K 31/47 20060101AFI20090325BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20101126 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110625 |