EP2043688A4 - TREATMENT OF TUMORS IN PEDIATRIC PATIENTS WITH EPIDERMALLY GROWTH FACTOR RECEPTOR ANTAGONISTS - Google Patents

TREATMENT OF TUMORS IN PEDIATRIC PATIENTS WITH EPIDERMALLY GROWTH FACTOR RECEPTOR ANTAGONISTS

Info

Publication number
EP2043688A4
EP2043688A4 EP07813400A EP07813400A EP2043688A4 EP 2043688 A4 EP2043688 A4 EP 2043688A4 EP 07813400 A EP07813400 A EP 07813400A EP 07813400 A EP07813400 A EP 07813400A EP 2043688 A4 EP2043688 A4 EP 2043688A4
Authority
EP
European Patent Office
Prior art keywords
tumors
treatment
growth factor
receptor antagonists
factor receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07813400A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2043688A2 (en
Inventor
Eric Rowinsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImClone LLC
Original Assignee
ImClone Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ImClone Systems Inc filed Critical ImClone Systems Inc
Publication of EP2043688A2 publication Critical patent/EP2043688A2/en
Publication of EP2043688A4 publication Critical patent/EP2043688A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP07813400A 2006-07-27 2007-07-26 TREATMENT OF TUMORS IN PEDIATRIC PATIENTS WITH EPIDERMALLY GROWTH FACTOR RECEPTOR ANTAGONISTS Withdrawn EP2043688A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83348706P 2006-07-27 2006-07-27
PCT/US2007/074448 WO2008014386A2 (en) 2006-07-27 2007-07-26 Treatment of tumors in pediatric patients with epidermal growth factor receptor antagonists

Publications (2)

Publication Number Publication Date
EP2043688A2 EP2043688A2 (en) 2009-04-08
EP2043688A4 true EP2043688A4 (en) 2009-11-11

Family

ID=38982334

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07813400A Withdrawn EP2043688A4 (en) 2006-07-27 2007-07-26 TREATMENT OF TUMORS IN PEDIATRIC PATIENTS WITH EPIDERMALLY GROWTH FACTOR RECEPTOR ANTAGONISTS

Country Status (15)

Country Link
EP (1) EP2043688A4 (es)
JP (1) JP2009544736A (es)
KR (1) KR20090033841A (es)
CN (1) CN101484186A (es)
AU (1) AU2007279261A1 (es)
BR (1) BRPI0712368A2 (es)
CA (1) CA2654911A1 (es)
CR (1) CR10486A (es)
EA (1) EA200870603A1 (es)
EC (1) ECSP089011A (es)
MX (1) MX2008016187A (es)
NO (1) NO20085182L (es)
TN (1) TNSN08512A1 (es)
WO (1) WO2008014386A2 (es)
ZA (1) ZA200810600B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210148228A (ko) * 2019-03-27 2021-12-07 내셔날 리서치 카운실 오브 캐나다 항-EGFRvIII 항체 및 그의 항원-결합 단편

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COMBS STEPHANIE E ET AL: "Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT) - phase I/II trial: study protocol", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 6, no. 1, 18 May 2006 (2006-05-18), pages 133, XP021016124, ISSN: 1471-2407 *
FURMAN W L: "A Phase I Study of Gefitinib and irinotecan (IRN) in pediatric patients with refractory solid tumors", J CLIN ONCOL, vol. 22, no. 14S, 2004, pages 8521, XP002540583, Retrieved from the Internet <URL:http://meeting.ascopubs.org/cgi/content/abstract/22/14_suppl/8521> [retrieved on 20090807] *
KREMPIEN R ET AL: "Randomized phase II - study evaluating EGFR targeting therapy with Cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer - PARC: study protocol [ISRCTN56652283]", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 5, no. 1, 11 October 2005 (2005-10-11), pages 131, XP021004738, ISSN: 1471-2407 *

Also Published As

Publication number Publication date
JP2009544736A (ja) 2009-12-17
ECSP089011A (es) 2009-01-30
KR20090033841A (ko) 2009-04-06
WO2008014386A2 (en) 2008-01-31
MX2008016187A (es) 2009-01-20
NO20085182L (no) 2009-04-24
BRPI0712368A2 (pt) 2012-06-05
ZA200810600B (en) 2009-11-25
WO2008014386A3 (en) 2008-07-03
CA2654911A1 (en) 2008-01-30
CN101484186A (zh) 2009-07-15
AU2007279261A1 (en) 2008-01-31
EA200870603A1 (ru) 2009-06-30
CR10486A (es) 2009-02-23
TNSN08512A1 (en) 2010-04-14
EP2043688A2 (en) 2009-04-08

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