EP2023852A4 - Biomolekül-verbundene biomimetische gerüste - Google Patents

Biomolekül-verbundene biomimetische gerüste

Info

Publication number
EP2023852A4
EP2023852A4 EP07795989A EP07795989A EP2023852A4 EP 2023852 A4 EP2023852 A4 EP 2023852A4 EP 07795989 A EP07795989 A EP 07795989A EP 07795989 A EP07795989 A EP 07795989A EP 2023852 A4 EP2023852 A4 EP 2023852A4
Authority
EP
European Patent Office
Prior art keywords
biomolecule
linked
biomimetic scaffolds
biomimetic
scaffolds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07795989A
Other languages
English (en)
French (fr)
Other versions
EP2023852A2 (de
Inventor
Craig Hashi
Song Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2007/061253 external-priority patent/WO2007090102A2/en
Application filed by University of California filed Critical University of California
Publication of EP2023852A2 publication Critical patent/EP2023852A2/de
Publication of EP2023852A4 publication Critical patent/EP2023852A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EP07795989A 2006-06-09 2007-06-11 Biomolekül-verbundene biomimetische gerüste Withdrawn EP2023852A4 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US80435006P 2006-06-09 2006-06-09
US86178006P 2006-11-30 2006-11-30
PCT/US2007/061253 WO2007090102A2 (en) 2006-01-27 2007-01-29 Biomimetic scaffolds
US11/668,448 US20070269481A1 (en) 2006-01-27 2007-01-29 Biomimetic Scaffolds
US92492607P 2007-06-05 2007-06-05
PCT/US2007/013736 WO2007146261A2 (en) 2006-06-09 2007-06-11 Biomolecule-linked biomimetic scaffolds

Publications (2)

Publication Number Publication Date
EP2023852A2 EP2023852A2 (de) 2009-02-18
EP2023852A4 true EP2023852A4 (de) 2012-06-27

Family

ID=40243723

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07795989A Withdrawn EP2023852A4 (de) 2006-06-09 2007-06-11 Biomolekül-verbundene biomimetische gerüste

Country Status (9)

Country Link
EP (1) EP2023852A4 (de)
JP (1) JP2009540878A (de)
KR (1) KR20090024249A (de)
AU (1) AU2007258379A1 (de)
CA (1) CA2654840A1 (de)
IL (1) IL195801A0 (de)
MX (1) MX2008015695A (de)
RU (1) RU2009100654A (de)
WO (1) WO2007146261A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1974015A4 (de) * 2006-01-27 2012-07-04 Univ California Biomimetische gerüste
EP2341865A4 (de) 2008-10-07 2014-01-08 Nanonerve Inc Mehrlagige faserpolymergerüste, herstellungsverfahren und anwendungsverfahren
US8591567B2 (en) 2008-11-25 2013-11-26 Edwards Lifesciences Corporation Apparatus and method for in situ expansion of prosthetic device
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
WO2011127478A1 (en) 2010-04-09 2011-10-13 Nanovasc, Inc. Sleeve for graft and method
WO2011146046A1 (en) * 2010-05-17 2011-11-24 Yale University System for seeding cells onto three dimensional scaffolds
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
EP2412798A1 (de) * 2010-07-27 2012-02-01 Gambro Lundia AB Biomimetische Membran zur Kultivierung von Zellen
EP2646065A4 (de) 2010-12-05 2016-03-23 Nanonerve Inc Faserpolymergerüste mit diametral gemusterten polymerfasern
EP2661243B1 (de) * 2011-01-06 2022-10-12 Humacyte, Inc. Gewebegezüchtete konstrukte
CN102698323B (zh) * 2012-05-14 2014-07-23 西南交通大学 一种抗凝血材料的制备方法
ES2470495B1 (es) 2012-12-19 2015-05-14 Universidad De Castilla La Mancha Materiales, métodos y dispositivos para estimular y dirigir la proliferación y migración de progenitores neurales y el crecimiento axonal y dendrítico
KR101526308B1 (ko) * 2013-01-23 2015-06-09 아주대학교산학협력단 생체 내 이식 적용 및 중장기 생체소재 분해 추적용 조영제가 화학적 결합된 생체소재 및 이의 제조방법
WO2015122478A1 (ja) 2014-02-14 2015-08-20 日産化学工業株式会社 活性エステル基を含む繊維製造用組成物及びその繊維を用いた細胞培養足場材料
CN104153123B (zh) * 2014-07-30 2016-08-24 东华大学 一种柔性氧化钛纳米纤维膜及其制备方法
CN104153124B (zh) * 2014-07-30 2016-11-02 东华大学 一种柔性稀土氧化物纳米纤维膜及其制备方法
EP4091639A1 (de) * 2015-08-17 2022-11-23 The Johns Hopkins University In-situ-herstellung von verbundmaterial zur gewebewiederherstellung
WO2017041029A1 (en) 2015-09-02 2017-03-09 Edwards Lifesciences Corporation Spacer for securing a transcatheter valve to bioprosthetic cardiac structure
US10982055B2 (en) 2015-10-05 2021-04-20 The Regents Of The University Of California Thermoreversible polymers and methods of use thereof
EP3845207A1 (de) * 2016-05-16 2021-07-07 Edwards Lifesciences Corporation System und verfahren zum aufbringen von material auf einen stent
US10456245B2 (en) 2016-05-16 2019-10-29 Edwards Lifesciences Corporation System and method for applying material to a stent
USD846122S1 (en) 2016-12-16 2019-04-16 Edwards Lifesciences Corporation Heart valve sizer
EP3743016A1 (de) 2018-01-23 2020-12-02 Edwards Lifesciences Corporation Halter für prothetische klappen, systeme und verfahren
AU2019267711A1 (en) 2018-05-09 2020-12-03 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
USD908874S1 (en) 2018-07-11 2021-01-26 Edwards Lifesciences Corporation Collapsible heart valve sizer
CN110548187A (zh) * 2019-09-16 2019-12-10 生纳科技(上海)有限公司 一种即时穿刺透析型纳米纤维人工血管

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
WO2007090102A2 (en) * 2006-01-27 2007-08-09 The Regents Of The University Of California Biomimetic scaffolds

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Publication number Priority date Publication date Assignee Title
CA2000887A1 (en) * 1988-11-01 1990-05-01 Cecilia S.L. Ku Thromboresistant materials and methods for making same
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US6889082B2 (en) * 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6610004B2 (en) * 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6303136B1 (en) * 1998-04-13 2001-10-16 Neurotech S.A. Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
US6391333B1 (en) * 1999-04-14 2002-05-21 Collagen Matrix, Inc. Oriented biopolymeric membrane
AU2001273632A1 (en) * 2000-06-23 2002-01-08 Drexel University Polymeric, fiber matrix delivery systems for bioactive compounds
US6893431B2 (en) * 2001-10-15 2005-05-17 Scimed Life Systems, Inc. Medical device for delivering patches
US20060085063A1 (en) * 2004-10-15 2006-04-20 Shastri V P Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
WO2007090102A2 (en) * 2006-01-27 2007-08-09 The Regents Of The University Of California Biomimetic scaffolds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZUWEI MA ET AL: "Grafting of Gelatin on Electrospun Poly(caprolactone) Nanofibers to Improve Endothelial Cell Spreading and Proliferation and to Control Cell Orientation", TISSUE ENGINEERING, 1 July 2005 (2005-07-01), United States, pages 1149 - 1158, XP055027680, Retrieved from the Internet <URL:http://online.liebertpub.com/doi/pdf/10.1089/ten.2005.11.1149> [retrieved on 20120521], DOI: 10.1089/ten.2005.11.1149 *

Also Published As

Publication number Publication date
EP2023852A2 (de) 2009-02-18
WO2007146261A3 (en) 2008-12-04
RU2009100654A (ru) 2010-07-20
CA2654840A1 (en) 2007-12-21
MX2008015695A (es) 2009-02-06
IL195801A0 (en) 2009-09-01
AU2007258379A1 (en) 2007-12-21
WO2007146261A2 (en) 2007-12-21
KR20090024249A (ko) 2009-03-06
JP2009540878A (ja) 2009-11-26

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