EP1963522A4 - Conjugues de polysaccharides-proteines derivatises meningococciques multivalents et vaccin - Google Patents

Conjugues de polysaccharides-proteines derivatises meningococciques multivalents et vaccin

Info

Publication number
EP1963522A4
EP1963522A4 EP05858729A EP05858729A EP1963522A4 EP 1963522 A4 EP1963522 A4 EP 1963522A4 EP 05858729 A EP05858729 A EP 05858729A EP 05858729 A EP05858729 A EP 05858729A EP 1963522 A4 EP1963522 A4 EP 1963522A4
Authority
EP
European Patent Office
Prior art keywords
vaccine
protein conjugates
derivatized polysaccharide
multivalent meningococcal
meningococcal derivatized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05858729A
Other languages
German (de)
English (en)
Other versions
EP1963522A2 (fr
Inventor
Robert P Ryall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Inc
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of EP1963522A2 publication Critical patent/EP1963522A2/fr
Publication of EP1963522A4 publication Critical patent/EP1963522A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP05858729A 2005-12-22 2005-12-22 Conjugues de polysaccharides-proteines derivatises meningococciques multivalents et vaccin Withdrawn EP1963522A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/046886 WO2007102797A2 (fr) 2005-12-22 2005-12-22 Conjugues de polysaccharides-proteines derivatises meningococciques multivalents et vaccin

Publications (2)

Publication Number Publication Date
EP1963522A2 EP1963522A2 (fr) 2008-09-03
EP1963522A4 true EP1963522A4 (fr) 2010-05-12

Family

ID=38475284

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05858729A Withdrawn EP1963522A4 (fr) 2005-12-22 2005-12-22 Conjugues de polysaccharides-proteines derivatises meningococciques multivalents et vaccin

Country Status (6)

Country Link
EP (1) EP1963522A4 (fr)
JP (1) JP2009521434A (fr)
CN (1) CN101443454A (fr)
BR (1) BRPI0516372A (fr)
MX (1) MX2007007790A (fr)
WO (1) WO2007102797A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102327605B (zh) * 2011-08-25 2013-01-30 成都康华生物制品有限公司 四价脑膜炎球菌多糖疫苗的制备工艺
CN102809656B (zh) * 2012-08-26 2014-09-03 云南沃森生物技术股份有限公司 一种脑膜炎球菌多糖结合疫苗成品各群游离多糖含量的测定方法
ES2672045T3 (es) * 2014-07-25 2018-06-12 Biosynth S.R.L. Vacunas de productos glicoconjugados que comprenden unidades básicas de una construcción molecular que expresa múltiples epítopos incorporados para la formulación de una vacuna de amplio espectro contra infecciones debidas a bacterias enteropatógenas
CN104383532A (zh) * 2014-12-02 2015-03-04 云南沃森生物技术股份有限公司 一种用乙肝表面抗原为载体蛋白的细菌多糖蛋白结合物疫苗及其制备方法
CA3033364A1 (fr) 2016-09-02 2018-03-08 Sanofi Pasteur, Inc. Vaccin contre neisseria meningitidis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058670A1 (fr) * 1997-06-24 1998-12-30 Chiron Corporation Procedes permettant d'immuniser des adultes grace a des compositions de vaccins anti-meningococcique
WO2005004909A2 (fr) * 2003-05-07 2005-01-20 Aventis Pasteur, Inc. Methode permettant d'obtenir une immunogenicite amelioree par rapport a la vaccination meningococcique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5425946A (en) * 1992-08-31 1995-06-20 North American Vaccine, Inc. Vaccines against group C Neisseria meningitidis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058670A1 (fr) * 1997-06-24 1998-12-30 Chiron Corporation Procedes permettant d'immuniser des adultes grace a des compositions de vaccins anti-meningococcique
WO2005004909A2 (fr) * 2003-05-07 2005-01-20 Aventis Pasteur, Inc. Methode permettant d'obtenir une immunogenicite amelioree par rapport a la vaccination meningococcique

Also Published As

Publication number Publication date
JP2009521434A (ja) 2009-06-04
WO2007102797A2 (fr) 2007-09-13
MX2007007790A (es) 2009-06-05
WO2007102797A3 (fr) 2009-04-16
EP1963522A2 (fr) 2008-09-03
BRPI0516372A (pt) 2008-09-02
CN101443454A (zh) 2009-05-27

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070723

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK YU

RIN1 Information on inventor provided before grant (corrected)

Inventor name: RYALL, ROBERT, P.

R17D Deferred search report published (corrected)

Effective date: 20090416

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 39/095 20060101ALI20090429BHEP

Ipc: A61K 39/02 20060101AFI20090429BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20100414

17Q First examination report despatched

Effective date: 20101202

DAX Request for extension of the european patent (deleted)
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Effective date: 20140701