EP1957378B1 - Durchdrückpackung mit falzlinien - Google Patents

Durchdrückpackung mit falzlinien Download PDF

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Publication number
EP1957378B1
EP1957378B1 EP06824308A EP06824308A EP1957378B1 EP 1957378 B1 EP1957378 B1 EP 1957378B1 EP 06824308 A EP06824308 A EP 06824308A EP 06824308 A EP06824308 A EP 06824308A EP 1957378 B1 EP1957378 B1 EP 1957378B1
Authority
EP
European Patent Office
Prior art keywords
blister pack
weakness
accommodation
lines
connecting part
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP06824308A
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English (en)
French (fr)
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EP1957378A1 (de
Inventor
Patrick Antonius Hendrikus Meeren
Anouk Maria Louisa Meeren
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Individual
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Individual
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Publication date
Application filed by Individual filed Critical Individual
Publication of EP1957378A1 publication Critical patent/EP1957378A1/de
Application granted granted Critical
Publication of EP1957378B1 publication Critical patent/EP1957378B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
    • B65D83/0472—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container the band being wound in flat spiral, folded in accordion or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/527—Tear-lines for separating a package into individual packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2585/00—Containers, packaging elements or packages specially adapted for particular articles or materials
    • B65D2585/56—Containers, packaging elements or packages specially adapted for particular articles or materials for medicinal tablets or pills

Definitions

  • the invention relates to a blister pack for dosage forms of a pharmaceutical formulation which is suitable for enteral administration, such as tablets, pills or capsules, comprising a plurality of accommodation units which are interconnected along lines of weakness, each accommodation unit being provided with a pierceable base sheet and a cap part which is fixed to the base sheet, an accommodation space for accommodating an object being formed between the base sheet and the cap part of each accommodation unit, each accommodation space containing a dosage form.
  • Such a blister pack is known.
  • the blister pack forms a primary pack.
  • the packed dosage forms such as tablets, pills, capsules and the like, are also indicated below by the term objects. These objects are situated between the cap part and the base sheet.
  • the cap part can be deformed by heat, so that individual accommodation units are produced. Each accommodation unit is sufficiently large to contain the form of the individual object.
  • the cap part is closed off by the base sheet, which is fixed to the cap part.
  • This type of blister pack is sold in a container, such as a cardboard box, which surrounds the blister pack.
  • the container forms a secondary pack.
  • a disadvantage of this pack is, however, that because of the design of the blister pack described above, optimum use cannot be made of the available volume of the container, i.e. the secondary pack.
  • the latter contains a considerable empty space.
  • the base sheet does not provide sufficient security, with the result that the contents can come out of it prematurely. This means that it is possible for the objects to come out of the pack accidentally.
  • sharp edges occur on the pack, so that the user can injure himself and/or can damage the environment, and in particular the base sheet of the pack.
  • the small mutual distance between the individual accommodation units makes them difficult to tear off. The result is that a number of adjacent base sheets of the individual accommodation units can be opened accidentally.
  • the individual redistribution of the individual accommodation units such as commonly occurs in institutions, is time-consuming and inefficient.
  • An object of the invention it to provide a blister pack which at least partially overcomes one or more of the abovementioned drawbacks.
  • the blister pack comprises a plurality of connecting parts, each of which is connected by way of two respective lines of weakness to at least one accommodation unit in each case.
  • the blister pack according to the invention can be folded up along its lines of weakness.
  • the connecting parts which are provided between the accommodation units in such a way that they can be folded along the lines of weakness
  • the accommodation units can be placed, for example, alternately back to back against each other. This means that the space between the individual accommodation units is reduced, in other words the accommodation units of the folded blister pack according to the invention are packed more closely against each other. Since the volume taken up in the blister pack is then reduced, this produces a saving of space.
  • the empty space in the secondary pack which surrounds the blister pack according to the invention can be reduced.
  • the secondary pack can consequently contain a blister pack with more objects, or the secondary pack can be made smaller while accommodating a blister pack with the same number of objects.
  • the blister pack can, for example, contain ten pills or more.
  • the connecting parts and the accommodation units connected to them can be aligned with each other in order to form an elongated, possibly folded strip.
  • Said strip therefore comprises a series of accommodation units and connecting parts, which are connected to each other by way of the lines of weakness.
  • the blister pack according to the invention it is also possible for the blister pack according to the invention to comprise a plurality of such series or strips which are interconnected parallel to and adjacent to each other along lines of weakness.
  • a further advantage of the blister pack according to the invention is that it means that less secondary packaging material is needed.
  • the primary packaging material is also reduced by reducing the contact surface between the individual accommodation units by using connecting parts, with the result that it is possible to provide the individual accommodation units with a maximum material-saving method, which is possibly based on the contents of the individual accommodation units.
  • the blister pack according to the invention prevents damage to the pack itself, injury to the user and damage to the environment of the pack, owing to the fact that the accommodation unit does not have any sharp corners.
  • Another advantage is that user convenience is increased by the fact of simply tearing along the lines of weakness of the individual accommodation units, since the mutual distance between the individual accommodation units is increased in pairs by the mutual connecting parts. This gives users more space to press the individual contents per accommodation unit out of the primary pack through base sheet, which reduces the risk of accidentally pressing out several accommodation units.
  • Another advantage is more efficient redistribution of the individual accommodation units by the fact that the connecting parts make it possible to wind the primary packaging material onto a core body, so that large quantities of individual accommodation units can be supplied on a roll.
  • a pharmaceutical pack according to the preamble of claim 1 is disclosed in US3659706 .
  • This pack has a pair of blister sheets which are interconnected by a hinge part.
  • the blister sheets can be folded along the hinge part, so that the blister sheets lie above one another.
  • the cap parts of the blister sheets are accommodated inside each other after folding.
  • This pack is not, however, provided with a plurality of connecting parts, so that the accommodation units of the blister sheets cannot be individually folded.
  • the base sheet of this blister pack faces outwards, which increases the risk of damage.
  • a pack is disclosed in GB 2096574 .
  • This pack comprises a transparent cover which is fixed to a cardboard base sheet.
  • a bottle is accommodated between the two.
  • a plurality of these packs can be connected to each other by way of perforation lines.
  • a spacer is provided between two pairs of interconnected packs. This makes it possible to fold up the packs.
  • this pack does not relate to dosage forms of a pharmaceutical formulation which is suitable for enteral administration.
  • the lines of weakness of the connecting part may be situated on either side of said connecting part.
  • the lines of weakness are provided on opposite edges of the connecting part.
  • the lines of weakness extend substantially parallel to each other.
  • the connecting part or each connecting part prefferably be connected by way of each line of weakness thereof to a pair of accommodation units which are directly connected to each other by way of a line of weakness.
  • two accommodation units in each case are directly connected to each other along a line of weakness, which two accommodation units form a pair.
  • a connecting part is provided in each case between said pairs of accommodation units, which connecting part is connected by way of lines of weakness to each pair.
  • each accommodation unit prefferably be of a height which is determined by the distance running substantially perpendicularly relative to the base sheet from the base sheet to the top of the cap part, and for the connecting part to be of a length which is determined by the distance between its lines of weakness, and for the length of the connecting part to be substantially greater than or equal to the height of an accommodation unit.
  • the lines of weakness of a connecting part are the lines of weakness by means of which said connecting part is connected to one or two accommodation units in each case.
  • the length of the connecting part is at least equal to substantially twice the height of an accommodation unit. If the ratio of said length and said height is substantially equal to two, the blister pack can be folded up in zigzag fashion to a particularly compact size.
  • the length of the connecting parts can, however, also be greater than twice the height of the accommodation units.
  • each accommodation unit prefferably be of a length which is determined by the distance between the lines of weakness by means of which said accommodation unit is connected to a connecting part and/or further accommodation unit, and for the length of the connecting part to be substantially less than the length of the accommodation unit.
  • the lines of weakness of an accommodation unit are the lines of weakness by means of which said accommodation unit is connected to a connecting part or a further accommodation unit in each case.
  • each accommodation unit and each connecting part is of a respective width which in each case is determined by its maximum distance in the direction running substantially parallel to the lines of weakness, and the width of the connecting part is less than the width of an accommodation unit.
  • the connecting parts are then narrower than the accommodation units.
  • each accommodation unit substantially corresponds to the circumference of the object accommodated in it. If the blister pack according to the invention is filled with, for example, disc-shaped pills, which are substantially round, it is preferable for each accommodation unit also to be of a round shape.
  • the blister pack can comprise various materials.
  • the base sheet of the accommodation units is made of aluminium
  • the cap part of the accommodation units is made of plastic, such as polyvinyl chloride (PVC) or polyethylene terephthalate (PET).
  • PVC polyvinyl chloride
  • PET polyethylene terephthalate
  • the base sheet and/or the cap part can, however, also comprise other materials.
  • amorphous polyamide PA
  • polyethylene naphthalate PEN
  • PCTFE polychlorotrifluoroethylene
  • PVC polyvinyl chloride
  • PVDC polyvinylidene chloride
  • PP polypropylene
  • COC cyclo-olefin copolymer
  • LCP liquid crystal polymer
  • EVOH ethylene vinyl alcohol
  • PVOH polyvinyl alcohol
  • PAN polyacrylonitrile
  • PS polystyrene
  • biaxially oriented polyamide OPA
  • chlorotrifluoroethyelene CTFE
  • HDPE high-density polyethylene
  • LDPE low-density polyethylene
  • the base sheet and/or the cap part can also be made of, for example, any combination of the abovementioned materials.
  • the invention also relates to an assembly of a blister pack of the type described above and a container in which said blister pack is accommodated. It is possible here for the blister pack to be folded up in zigzag fashion and for the dimensions of the container to correspond substantially to the dimensions of the folded blister pack. The blister pack folded up in zigzag fashion is then accommodated in a close fit in the container, for example a box. The pack formed by the assembly is compact.
  • the invention furthermore relates to a method for packaging objects such as tablets, pills or capsules, comprising the provision of a blister pack of the type described above and folding up the blister pack, preferably in zigzag fashion, along the lines of weakness.
  • the embodiment of the blister pack shown in Figures 1 and 2 comprises a strip of ten accommodation units 1.
  • the number of accommodation units can, of course, be different.
  • the accommodation units 1 form a single row.
  • the blister pack has several pairs of accommodation units directly connected to each other.
  • a line of weakness 2 is situated between each pair of accommodation units 1.
  • the blister pack comprises a number of connecting parts 3 - in this exemplary embodiment four connecting parts 3.
  • the connecting parts 3 are provided between two pairs of accommodation units 1 in each case.
  • the connecting parts 3 are connected by means of lines of weakness 2 to the adjacent accommodation units 1.
  • the blister pack can be folded up in zigzag fashion along the lines of weakness to the state shown in Figure 1A . From the folded state the accommodation units can be opened out or deployed, as shown in Figures 1B-D .
  • Figures 1A and 1B furthermore show diagrammatically by dashed and dotted lines a container in which the blister pack can be accommodated.
  • the blister pack forms a primary pack
  • the container forms a secondary pack.
  • the dimensions of the container are adapted to the dimensions of the blister pack in the folded state. Between the inside of the container and the folded blister pack there is only a relatively small amount of play.
  • the container can be in different forms.
  • the container is in the form of a cardboard box with a lip on one end face or on both end faces. The lip can be opened out to reach the blister pack.
  • this exemplary embodiment has only a single row of accommodation units 1, there can be an odd number of accommodation units 1. If a doctor prescribes a treatment of an odd number of pills, for example 5 or 7, the blister pack according to the invention can be adapted to this. This means that no accommodation units remain unused, as regularly occurs in the case of known pharmaceutical blister packs.
  • the embodiment shown in Figure 3 comprises two parallel strips of accommodation units 1.
  • the strips form two adjacent rows of accommodation units 1.
  • the accommodation units 1 of each strip are connected to each other in pairs by one connecting part 3 in each case.
  • Each connecting part 3 is connected by way of two opposite lines of weakness 2 to two accommodation units 1 in each case, which accommodation units are directly connected to each other by way of a line of weakness 2.
  • the parallel strips of accommodation units 1 are fixed to each other at laterally adjacent accommodation units 1 thereof in each case.
  • this exemplary embodiment comprises two strips of ten accommodation units 1, i.e. a total of twenty accommodation units 1, said double blister pack can, of course, comprise more or fewer accommodation units 1.
  • the accommodation units 1 of the embodiments shown in Figures 1 and 2 each comprise a pierceable base sheet or bottom sheet 5 and a cap part 4, which is fixed to the base sheet 5 (see Figure 4A ).
  • the cap part 4 of each accommodation unit 1 has a circumferential edge which is aligned relative to the pierceable base sheet 5 (see also Figures 4B and 4C ).
  • the cap part 4 and the base sheet 5 bound an interior accommodation space 7.
  • the accommodation space 7 contains a dosage form 6 of a pharmaceutical formulation which is suitable for enteral or oral administration, such as tablets, pills or capsules.
  • the dosage forms 6 form objects packed in the blister pack.
  • Figure 4A shows furthermore that the connecting part 3 can have a further line of weakness 2'.
  • the line of weakness 2' is, for example, provided centrally between the lines of weakness 2 by means of which the connecting part 3 is connected to the adjacent accommodation units 1.
  • the further line of weakness 2' reduces the risk of the base sheet 5 tearing when an accommodation unit 1 is removed from the blister pack.
  • Said blister pack can comprise one strip or two or more laterally connected strips of accommodation units 1. Although the strip or strips in Figures 5-7 comprise six accommodation units, the number of accommodation units 1 can differ from this number.
  • the accommodation units 1 are connected to each other in pairs in each case by a connecting part 3, which is provided with lines of weakness 2. Each accommodation unit 1 is connected on either side of said unit by way of a line of weakness 2 in each case to a connecting part 3 and a further accommodation unit 1 respectively.
  • the connecting part 3 can be designed in various ways according to the invention.
  • the connecting part is formed as shown in Figures 8A-D .
  • the connecting parts 3, 103, 203, 303 are provided between two pairs of accommodation units 1.
  • the connecting parts 3, 103, 203, 303 are connected by way of lines of weakness 2 to said pairs of accommodation units 1.
  • the accommodation units 1 according to the invention can be of a round shape.
  • the line of weakness between the accommodation unit 1 and the connecting part 3 is preferably straight, but it can also correspond to the round shape of the accommodation unit (see Figure 9 ).
  • the cap part 4 is connected to the pierceable base sheet 5 for the purpose of protecting the enclosed object 6. There may be play between the object 6 and the cap part 4 and/or base sheet 5.
  • the length L of the connecting part 3 is twice the height H of the accommodation units 1.
  • the accommodation units 1 are connected to each other in pairs by way of the lines of weakness 2, with the interposition of a connecting element 3 in each case.
  • the accommodation units I of each pair are likewise connected to each other by way of a line of weakness 2. Adapting the length L of the connecting parts 3 and the height H of the accommodation units 1 of the blister pack to each other makes the blister pack particularly compact in the folded state.
  • the strip of accommodation units 1 and connecting parts 3 which are connected by lines of weakness 2 is rolled up in a direction 9 around a core body 8.
  • one strip or a plurality of strips of accommodation units 1 laterally connected to each other can be rolled up on the core body 8.
  • said rolled-up strip or strips of accommodation units not to have any connecting parts 3, i.e. the accommodation units in this case are connected to each other only by way of lines of weakness.
  • FIG. 12 and 13 A further embodiment of the blister pack according to the invention is shown in Figures 12 and 13 .
  • Said blister pack can be folded up in zigzag fashion along the lines of weakness 2, the base sheets 5 resting against the cap parts 4.
  • the blister pack is shown opened out in Figure 13 .
  • a connecting part 3 is situated between each pair of adjacent accommodation units 1, which connecting part is connected by way of lines of weakness 2 to said accommodation units 1.
  • the cap parts 4 of adjacent accommodation units 1 lie on either side of the base sheet 5.
  • the length of the connecting parts 3 in this exemplary embodiment is substantially equal to the height of the accommodation units 1.
  • the invention is not limited by the exemplary embodiments shown in the figures, which the person skilled in the art can adapt in various ways.
  • the number of accommodation units 1 of the blister pack according to the invention can be extended by adding further strips of accommodation units 1 and connecting parts 3 and/or extending one or more strips by adding further accommodation units 1 and connecting parts 3. It is also possible according to the invention for more than one or two accommodation units 1 to be provided between two connecting parts 3 of a strip. It is even possible for the number of accommodation units 1 between two connecting parts 3 in a strip of accommodation units 1 and connecting parts 1 to vary.

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  • Chemical & Material Sciences (AREA)
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  • Packages (AREA)

Claims (15)

  1. Blisterpackung für Dosierungsformen einer pharmazeutischen Formulierung, die für enterale Verabreichung geeignet ist, beispielsweise Tabletten, Pillen oder Kapseln, wobei die Blisterpackung mehrere Aufnahmeeinheiten (1) aufweist, die entlang von Schwächelinien (2) miteinander verbunden sind, wobei jede Aufnahmeeinheit (1) mit einer durchdrückbaren Basisschicht (5) und einem an der Basisschicht (5) befestigten Kappenteil (4) versehen ist, wobei zwischen der Basisschicht (5) und dem Kappenteil (4) jeder Aufnahmeeinheit (1) ein Aufnahmeraum zum Aufnehmen einer Dosierungsform (6) gebildet ist, wobei jeder Aufnahmeraum eine Dosierungsform (6) aufweist, dadurch gekennzeichnet, dass die Blisterpackung mehrere Verbindungsteile (3) aufweist, von denen jeder über zwei jeweilige Schwächelinien (2) jeweils mit mindestens einer Aufnahmeeinheit (1) verbunden ist.
  2. Blisterpackung nach Anspruch 1, in welcher die Schwächelinien (2) des Verbindungsteils (3) beiderseits des Verbindungsteils angeordnet sind.
  3. Blisterpackung nach Anspruch 1 oder 2, in welcher jeder Verbindungsteil (3) über eine jeweilige Schwächelinie (2) mit einem Paar von Aufnahmeeinheiten (1) verbunden ist, die über eine Schwächelinie (2) direkt miteinander verbunden sind.
  4. Blisterpackung nach einem der vorstehenden Ansprüche, in welcher jede Aufnahmeeinheit (1) eine Höhe hat, die definiert ist als der im Wesentlichen senkrecht zur Basisschicht (5) verlaufende Abstand zwischen Basisschicht (5) und Kappenteil (4), und in welcher der Verbindungsteil (3) eine Länge hat, die definiert ist als der Abstand zwischen seinen Schwächelinien (2), und in welcher die Länge des Verbindungsteils (3) im Wesentlichen größer oder gleich der Höhe einer Aufnahmeeinheit (1) ist.
  5. Blisterpackung nach Anspruch 4, in welcher die Länge eines Verbindungsteils (3) mindestens gleich bis im Wesentlichen das Zweifache der Höhe einer Aufnahmeeinheit (1) ist.
  6. Blisterpackung nach Anspruch 4 oder 5, in welcher jede Aufnahmeeinheit (1) eine Länge hat, die definiert ist als der Abstand zwischen den Schwächelinien, durch welche die Aufnahmeeinheit (1) mit einem Verbindungsteil (3) und/oder einer anderen Aufnahmeeinheit (1) verbunden ist, und in welcher die Länge des Verbindungsteils (3) im Wesentlichen kleiner ist als die Länge der Aufnahmeeinheit (1).
  7. Blisterpackung nach einem der vorstehenden Ansprüche, in welcher die Blisterpackung entlang von mehr als zwei Schwächelinien (2) gefaltet ist.
  8. Blisterpackung nach Anspruch 7, in welcher die Basisschichten (5) mindestens zweier entlang einer Schwächelinie (2) miteinander verbundener Aufnahmeeinheiten (1) einander zugewandt sind.
  9. Blisterpackung nach einem der vorstehenden Ansprüche, in welcher die Basisschicht der Aufnahmeeinheiten aus Aluminium besteht und in welcher der Kappenteil der Aufnahmeeinheiten aus Kunststoff, beispielsweise Polyvinylchlorid (PVC) oder Polyethylenterephthalat (PET), besteht.
  10. Anordnung bestehend aus einer Blisterpackung nach einem der vorstehenden Ansprüche und einem Behälter, in welcher die Blisterpackung untergebracht ist.
  11. Anordnung nach Anspruch 10, in welcher die Blisterpackung entlang von mehr als zwei Schwächelinien (2) gefaltet ist und in welcher die Abmessungen des Behälters im Wesentlichen den Abmessungen der gefalteten Blisterpackung entsprechen.
  12. Verfahren zum Verpacken von Objekten (6), beispielsweise Tabletten, Pillen oder Kapseln, mit:
    - Bereitstellen einer Blisterpackung nach einem der vorstehenden Ansprüche,
    - Falten der Blisterpackung, vorzugsweise zickzackförmig, entlang der Schwächelinien (2).
  13. Verfahren nach Anspruch 12, in welchem die Basisschichten (5) mindestens zweier entlang einer Schwächelinie (2) direkt miteinander verbundener Aufnahmeeinheiten (1) zueinander hin gefaltet werden.
  14. Verfahren nach Anspruch 12 oder 13, in welchem die Kappenteile (4) mindestens zweier durch einen Verbindungsteil (3) miteinander verbundener Aufnahmeeinheiten (1) zueinander hin gefaltet werden.
  15. Verfahren nach einem der Ansprüche 12 bis 14, in welchem ein Behälter zur Aufnahme der Blisterpackung bereitgestellt wird und die gefaltete Blisterpackung in dem Behälter angeordnet wird.
EP06824308A 2005-12-06 2006-12-06 Durchdrückpackung mit falzlinien Not-in-force EP1957378B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1030608A NL1030608C2 (nl) 2005-12-06 2005-12-06 Blisterverpakking, samenstel van een blisterverpakking en een houder, alsmede werkwijze voor het verpakken van objecten.
PCT/NL2006/050306 WO2007067054A1 (en) 2005-12-06 2006-12-06 Blister pack with fold lines

Publications (2)

Publication Number Publication Date
EP1957378A1 EP1957378A1 (de) 2008-08-20
EP1957378B1 true EP1957378B1 (de) 2012-08-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP06824308A Not-in-force EP1957378B1 (de) 2005-12-06 2006-12-06 Durchdrückpackung mit falzlinien

Country Status (5)

Country Link
US (1) US20080302695A1 (de)
EP (1) EP1957378B1 (de)
HK (1) HK1120481A1 (de)
NL (1) NL1030608C2 (de)
WO (1) WO2007067054A1 (de)

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EP1889198B1 (de) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Pharma-informatiksystem
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
EP1920418A4 (de) 2005-09-01 2010-12-29 Proteus Biomedical Inc Implantierbare drahtlose kommunikationssysteme
EP3367386A1 (de) 2006-05-02 2018-08-29 Proteus Digital Health, Inc. Patientenspezifische therapieformen
JP5916277B2 (ja) 2006-10-25 2016-05-11 プロテウス デジタル ヘルス， インコーポレイテッド 摂取可能な制御活性化識別子
US8718193B2 (en) 2006-11-20 2014-05-06 Proteus Digital Health, Inc. Active signal processing personal health signal receivers
CN101686800A (zh) 2007-02-01 2010-03-31 普罗秋斯生物医学公司 可摄入事件标记器系统
EP2111661B1 (de) 2007-02-14 2017-04-12 Proteus Digital Health, Inc. Körperintegrierte stromquelle mit grossflächiger elektrode
EP2063771A1 (de) 2007-03-09 2009-06-03 Proteus Biomedical, Inc. Körperintegrierte vorrichtung mit ausfahrbarer antenne
WO2008112577A1 (en) 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a multi-directional transmitter
ITBO20070186A1 (it) * 2007-03-16 2008-09-17 Mechatronic Engineering S R L Confezione per confetti, caramelle e simili
US8115618B2 (en) 2007-05-24 2012-02-14 Proteus Biomedical, Inc. RFID antenna for in-body device
EP4011289A1 (de) 2007-09-25 2022-06-15 Otsuka Pharmaceutical Co., Ltd. Körperinterne vorrichtung mit virtueller dipol-signal-verstärkung
ES2661739T3 (es) 2007-11-27 2018-04-03 Proteus Digital Health, Inc. Sistemas de comunicación transcorporal que emplean canales de comunicación
WO2009105858A1 (en) * 2008-02-28 2009-09-03 Winpak Heat Seal Packaging Inc. Extrusion-coated lidding foil for push-through blister packaging
ES2840773T3 (es) 2008-03-05 2021-07-07 Otsuka Pharma Co Ltd Sistemas y marcadores de eventos ingeribles de comunicación multimodo
USD594348S1 (en) 2008-06-24 2009-06-16 Colgate-Palmolive Company Multiple product package
CN102159134B (zh) 2008-07-08 2015-05-27 普罗透斯数字保健公司 可摄取事件标记数据框架
US20110121019A1 (en) * 2008-07-10 2011-05-26 2P2D Solutions Ltd. Device for Drug Distribution and Method of Using Thereof
US8540633B2 (en) 2008-08-13 2013-09-24 Proteus Digital Health, Inc. Identifier circuits for generating unique identifiable indicators and techniques for producing same
CA2750158A1 (en) 2009-01-06 2010-07-15 Proteus Biomedical, Inc. Ingestion-related biofeedback and personalized medical therapy method and system
CN102365084B (zh) 2009-01-06 2014-04-30 普罗秋斯数字健康公司 药剂递送系统
CA2750734C (en) 2009-03-16 2013-11-05 Colgate-Palmolive Company Display package
GB2480965B (en) 2009-03-25 2014-10-08 Proteus Digital Health Inc Probablistic pharmacokinetic and pharmacodynamic modeling
EA201190281A1 (ru) 2009-04-28 2012-04-30 Протиус Байомедикал, Инк. Высоконадежные проглатываемые отметчики режима и способы их применения
US9149423B2 (en) 2009-05-12 2015-10-06 Proteus Digital Health, Inc. Ingestible event markers comprising an ingestible component
US8558563B2 (en) 2009-08-21 2013-10-15 Proteus Digital Health, Inc. Apparatus and method for measuring biochemical parameters
TWI401189B (zh) 2009-09-18 2013-07-11 Colgate Palmolive Co 用於產品之展示包裝盒
TWI517050B (zh) 2009-11-04 2016-01-11 普羅托斯數位健康公司 供應鏈管理之系統
UA109424C2 (uk) 2009-12-02 2015-08-25 Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки
US8479921B2 (en) 2009-12-09 2013-07-09 Amcor Flexibles, Inc. Child resistant blister package
SI2353573T1 (sl) * 2010-02-10 2012-12-31 E-Pharma Trento S.P.A. Nov ojačan pretisni omot
EP2547308B1 (de) * 2010-03-18 2014-08-06 MedComb Holding ApS Starrer einwegbehälter für pharmazeutische zusammensetzungen
US9597487B2 (en) 2010-04-07 2017-03-21 Proteus Digital Health, Inc. Miniature ingestible device
TWI557672B (zh) 2010-05-19 2016-11-11 波提亞斯數位康健公司 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置
EP2642983A4 (de) 2010-11-22 2014-03-12 Proteus Digital Health Inc Einnehmbare vorrichtung mit einem pharmazeutischen produkt
US20120145585A1 (en) 2010-12-08 2012-06-14 Id-Con, Llc Packaging systems and methods
ES2637388T3 (es) * 2011-02-04 2017-10-13 Taris Biomedical, Inc. Dispositivo implantable para la liberación controlada de un fármaco de baja solubilidad
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2013013108A2 (en) 2011-07-19 2013-01-24 Id-Con, Llc Packaging systems and methods
KR101898964B1 (ko) 2011-07-21 2018-09-14 프로테우스 디지털 헬스, 인코포레이티드 모바일 통신 장치, 시스템, 및 방법
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
WO2013128459A1 (en) * 2012-03-01 2013-09-06 2P2D Solutions Ltd. Folded blister chain, folding machine and folding method
EP2874886B1 (de) 2012-07-23 2023-12-20 Otsuka Pharmaceutical Co., Ltd. Verfahren zur herstellung verzehrbarer ereignismarker mit einem verzehrbaren bestandteil
MX340182B (es) 2012-10-18 2016-06-28 Proteus Digital Health Inc Aparato, sistema, y metodo para optimizar adaptativamente la disipacion de energia y la energia de difusion en una fuente de energia para un dispositivo de comunicacion.
TWI659994B (zh) 2013-01-29 2019-05-21 美商普羅托斯數位健康公司 高度可膨脹之聚合型薄膜及包含彼之組成物
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
EP3005281A4 (de) 2013-06-04 2017-06-28 Proteus Digital Health, Inc. System, vorrichtung und verfahren zur datensammlung und ergebnisbeurteilung
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
KR101483482B1 (ko) * 2013-12-10 2015-01-29 주식회사 블리스팩 개선된 시각성을 갖는 블리스터 포장체
CN107427408A (zh) 2015-01-21 2017-12-01 迈兰公司 药物包装和剂量方案系统
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
MX2019000888A (es) 2016-07-22 2019-06-03 Proteus Digital Health Inc Percepcion y deteccion electromagnetica de marcadores de evento ingeribles.
IL265827B2 (en) 2016-10-26 2023-03-01 Proteus Digital Health Inc Methods for producing capsules with ingestible event markers
WO2019081528A1 (en) * 2017-10-26 2019-05-02 Unilever Plc PRODUCT PACKAGING
WO2019081527A2 (en) 2017-10-26 2019-05-02 Unilever Plc PRODUCT PACKAGING
WO2019081526A2 (en) 2017-10-26 2019-05-02 Unilever Plc PACKAGING FOR PRODUCT
CN109573324A (zh) * 2019-01-16 2019-04-05 叶卫东 一次性补充液包装瓶
CN112849492A (zh) * 2021-01-14 2021-05-28 王骏桃 一种新型片状滤袋固体饮料的包装方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2771214A (en) * 1953-09-14 1956-11-20 Ivers Lee Co Dispensing carton for package strips
FR1127554A (fr) * 1955-06-04 1956-12-19 Vitrine en relief
US3659706A (en) 1970-04-24 1972-05-02 Parke Davis & Co Pharmacal package construction
DE2322055A1 (de) * 1973-05-02 1975-01-30 Bosch Gmbh Robert Kindersichere tablettenpackung
GB2096574B (en) 1981-04-10 1985-07-10 Fraser Chemicals Nottingham Lt Package assemblies
US5046618A (en) * 1990-11-19 1991-09-10 R. P. Scherer Corporation Child-resistant blister pack
SE9502370D0 (sv) * 1995-06-30 1995-06-30 Astra Ab Blister pack, especially for drugs, as well as method and device in manufacturing the same
SE515129C2 (sv) * 1996-07-01 2001-06-11 Astrazeneca Ab Blisterförpackning, apparat och förfarande för tillverkning av en blisterförpackning samt användning av en blisterförpackning
US5957358A (en) * 1997-11-14 1999-09-28 Eveready Battery Company, Inc. Battery strip dispenser
CN1286809A (zh) * 1998-11-18 2001-03-07 永备电池有限公司 带装式电池分售机
US6273260B1 (en) * 2000-03-08 2001-08-14 Eli Lilly And Company Pharmaceutical packaging system
US6845883B2 (en) * 2001-10-18 2005-01-25 Kenneth H. Pieri Toothpaste dispenser

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US20080302695A1 (en) 2008-12-11
EP1957378A1 (de) 2008-08-20
HK1120481A1 (en) 2009-04-03
NL1030608C2 (nl) 2007-06-07

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