EP1835819A1 - Sachets comprising plant sterol - Google Patents
Sachets comprising plant sterolInfo
- Publication number
- EP1835819A1 EP1835819A1 EP05814292A EP05814292A EP1835819A1 EP 1835819 A1 EP1835819 A1 EP 1835819A1 EP 05814292 A EP05814292 A EP 05814292A EP 05814292 A EP05814292 A EP 05814292A EP 1835819 A1 EP1835819 A1 EP 1835819A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- plant sterol
- sachet
- emulsifier
- sterol
- tea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 235000002378 plant sterols Nutrition 0.000 title claims abstract description 41
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 27
- 241001122767 Theaceae Species 0.000 claims abstract 3
- 229930182558 Sterol Natural products 0.000 claims description 30
- 235000003702 sterols Nutrition 0.000 claims description 30
- -1 fatty acid ester Chemical class 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 18
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 16
- 229930195729 fatty acid Natural products 0.000 claims description 16
- 239000000194 fatty acid Substances 0.000 claims description 16
- 150000003432 sterols Chemical class 0.000 claims description 13
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 claims description 11
- 235000013361 beverage Nutrition 0.000 claims description 11
- 229920000136 polysorbate Polymers 0.000 claims description 10
- 150000002148 esters Chemical class 0.000 claims description 8
- 229940076810 beta sitosterol Drugs 0.000 claims description 5
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 claims description 5
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 claims description 5
- 229950005143 sitosterol Drugs 0.000 claims description 5
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 claims description 4
- ARYTXMNEANMLMU-UHFFFAOYSA-N 24alpha-methylcholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(C)C(C)C)C1(C)CC2 ARYTXMNEANMLMU-UHFFFAOYSA-N 0.000 claims description 4
- LGJMUZUPVCAVPU-JFBKYFIKSA-N Sitostanol Natural products O[C@@H]1C[C@H]2[C@@](C)([C@@H]3[C@@H]([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)CC2)CC1 LGJMUZUPVCAVPU-JFBKYFIKSA-N 0.000 claims description 4
- ARYTXMNEANMLMU-ATEDBJNTSA-N campestanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]2(C)CC1 ARYTXMNEANMLMU-ATEDBJNTSA-N 0.000 claims description 4
- 239000000787 lecithin Substances 0.000 claims description 4
- 235000010445 lecithin Nutrition 0.000 claims description 4
- LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 claims description 4
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 3
- SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 claims description 3
- BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 claims description 3
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical group CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims description 3
- SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 claims description 3
- 235000000431 campesterol Nutrition 0.000 claims description 3
- 235000008216 herbs Nutrition 0.000 claims description 3
- 229920000223 polyglycerol Polymers 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
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- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 claims description 3
- DNISEZBAYYIQFB-PHDIDXHHSA-N (2r,3r)-2,3-diacetyloxybutanedioic acid Chemical class CC(=O)O[C@@H](C(O)=O)[C@H](C(O)=O)OC(C)=O DNISEZBAYYIQFB-PHDIDXHHSA-N 0.000 claims description 2
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 claims description 2
- OILXMJHPFNGGTO-NRHJOKMGSA-N Brassicasterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@](C)([C@H]([C@@H](/C=C/[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 OILXMJHPFNGGTO-NRHJOKMGSA-N 0.000 claims description 2
- OILXMJHPFNGGTO-ZRUUVFCLSA-N UNPD197407 Natural products C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)C=C[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZRUUVFCLSA-N 0.000 claims description 2
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 claims description 2
- OILXMJHPFNGGTO-ZAUYPBDWSA-N brassicasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]1(C)CC2 OILXMJHPFNGGTO-ZAUYPBDWSA-N 0.000 claims description 2
- 235000004420 brassicasterol Nutrition 0.000 claims description 2
- 238000004806 packaging method and process Methods 0.000 claims description 2
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 claims description 2
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 claims description 2
- 150000003445 sucroses Chemical class 0.000 claims description 2
- 239000011236 particulate material Substances 0.000 abstract description 4
- 244000269722 Thea sinensis Species 0.000 description 32
- 235000013616 tea Nutrition 0.000 description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 150000004665 fatty acids Chemical class 0.000 description 12
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- 235000019197 fats Nutrition 0.000 description 6
- 239000000796 flavoring agent Substances 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical class OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 238000001802 infusion Methods 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
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- 238000001816 cooling Methods 0.000 description 3
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- 230000032050 esterification Effects 0.000 description 3
- 238000005886 esterification reaction Methods 0.000 description 3
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 2
- 235000006468 Thea sinensis Nutrition 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 2
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- ZQPPMHVWECSIRJ-MDZDMXLPSA-N elaidic acid Chemical compound CCCCCCCC\C=C\CCCCCCCC(O)=O ZQPPMHVWECSIRJ-MDZDMXLPSA-N 0.000 description 2
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- 230000007407 health benefit Effects 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 2
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000000693 micelle Substances 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
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- 238000012360 testing method Methods 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- Sachets comprising plant sterol
- the invention relates to a porous sachet comprising plant sterol , emulsifier and a particulate component .
- Plant sterols are known to be difficult to apply in foods because of their poor solubility in fat and in aqueous systems .
- researchers have presented various ways to circumvent this problem.
- EP 594612 teaches that the esterification of stanols to fatty acids will lead to increased solubility in fat . Therefore stanol fatty acid esters may be incorporated into fat based food products such as margarines or butter in a relatively high level of around 10 to 20 wt% , such that average daily intake of these products will lead to ingestion of a suitable dosage of stanol ester for cholesterol lowering .
- EP-A-1059851 teaches that inclusion of sterols in suspensions is simplified by including a thickener in the system under ommission of emulsifier .
- the resulting compositions are claimed to be storage stable .
- WO-A-02/28204 also addresses the problem of including sterols in an aqueous dispersion .
- This document presents the finding that , when plant sterols and an emulsifier are heated together in the absence of other components , they are brought into homogeneous contact with each other while being fused, to form fine micelles which are as small as nanometers in size , when using subsequent homogenisation or high speed stirring processes .
- nanoscale micelles are superior in bioavailability, having no influence on the characteristic taste and flavor of the beverages , and applicable to almost all beverages such as tea .
- the invention relates to a porous sachet comprising plant sterol , an emulsifier, and a particulate component .
- the porous sachet comprises plant sterol , emulsifier and a particulate component .
- Suitable particulate material is such that it can serve as a beverage precursor material .
- the particulate component is preferably selected from the group comprising tea, coffee , bouillon, fat , herbs or a combination thereof .
- the particulate component is preferably chosen such that by immersing the sachet in an aqueous component such as water, a suitable beverage such as tea, or a soup or a sauce can be made from the composition in the sachet .
- the particulate component may be chosen from components that give a taste and flavour on extraction with hot or cold water or may be a component that dissolves partly or entirely in water .
- the sachet is suitable for use in an oily substance such as an emulsion of water and oil , or a cooking oil .
- the particulate component is tea .
- the wording tea covers tea leaves , including crushed and/or otherwise treated tea leaves, tea infusion composition, or any other form of particulate components derived from the tea plant .
- the sachet according to the invention may also be referred to as bag or infusion package or pouch or the like , all suitably referred to as "sachet" in the context of this invention.
- This sachet may have any 3 dimensional form such as round, square , rectangular, triangular .
- the sachet is a porous sachet .
- porous means that when the sachet is immersed in a liquid, components may diffuse in and out of the sachet through the pores .
- the material that is used to make the sachet is preferably characterised by a density in gram per square meter (g/m 2 ) of from 10 to 40 , preferably 11 to
- the porosity of the sachet material is such that it shows the desired infusion properties .
- Porosity in this context may be determined by air permeability and sand fall out tests .
- the air permeability in l/m 2 s is more than 1000 , more preferred more than 1500 l/m 2 s .
- the sand fall out at a particle size of from 106 to 150 ⁇ m is less than 10% , more preferred less than 6% .
- the sachet is suitably prepared from fibrous material such as cellulosic fibres .
- fibrous material such as cellulosic fibres .
- plastic fibres may be (partly) used .
- the emulsifier is preferably selected from the group comprising monoglycerides , lecithins , diglycerides , diacetyl tartaric acid esters of mono-and diglycerides , sucrose esters of fatty acids , sodium steoroyl lactylate (SSL) , citric acid esters of mono- and diglycerides , polyoxyethylene sorbitan esters , polyglycerol esters , or a combination thereof .
- Preferred emulsifiers are selected from monoglyceride, lecithin, diglycerides , polyoxyethylene sorbitan esters , or a combination thereof .
- emulsifiers are selected from monoglycerides , lecithins, diglycerides, polyoxyethylene sorbitan esters, polyglycerol esters, diacetyl tartaric acid esters of monoglyceride, sucrose esters and combinations thereof .
- the most preferred emulsifier are polyoxyethylene sorbitan esters .
- polyoxyethylene sorbitan esters are TweenTM60 and TweenTM20.
- proteins are not included in the term emulsifier.
- the amount of emulsifier is dependent on the type of emulsifier selected, but generally the level of emulsifier is from 1 to 70 wt% more preferred from 5 to 40 wt% on total weight of the composition present in the sachet . It will be appreciated that for each emulsifier there is an optimal amount for its functioning .
- Plant sterols can be classified in three groups , 4-desmethylsterols, 4-monomethylsterols and
- the plant sterol is selected from the group comprising ⁇ -sitosterol , ⁇ -sitostanol , campesterol , campestanol , stigmasterol , brassicasterol , brassicastanol or a mixture thereof .
- the sterols in a preferred embodiment are esterified with a fatty acid . It was found that the invention provides the largest effect for esters and a smaller effect for free sterols .
- plant sterols refers to both the free sterol and the ester of sterol with fatty acids , unless otherwise is specified.
- the sterols are esterified with one or more C 2 - 22 fatty acids .
- C2-22 fatty acid refers to any molecule comprising a C 2 - 22 main chain and at least one acid group .
- the C2-2 2 main chain may be partially substituted or side chains may be present .
- the C2-22 fatty acids are linear molecules comprising one or two acid group (s) as end group (s) .
- Most preferred are linear C 8 -22 fatty acids as occur in natural oils .
- Suitable examples of any such fatty acids are acetic acid, propionic acid, butyric acid, caproic acid, caprylic acid, capric acid .
- Other suitable acids are for example citric acid, lactic acid, oxalic acid and maleic acid . Most preferred are myristic acid, lauric acid, palmitic acid, stearic acid, arachidic acid, behenic acid, oleic acid, cetoleic acid, erucic acid, elaidic acid, linoleic acid and linolenic acid.
- a mixture of fatty acids may be used for esterification of the sterols .
- the emulsifier is present to ensure that the plant sterol is mostly present in emulsified state , such that the precipitation of plant sterol from the aqueous system is avoided .
- the ratio plant sterol to emulsifier (determined by dividing the amount of plant sterol in terms of free weight equivalent plant sterol , by the amount of emulsifier) is preferably from 0.05 to 10 , more preferred from 0.1 to 1.
- the amount of plant sterol (calculated as equivalent free plant sterol) is from 2 to 80 wt% , more preferred from 5 to 80 wt% on total weight of the particulate component . It will be appreciated that this amount will depend on the type of product and the intake level of this product . In a more preferred embodiment , the amount of plant sterol is from 5 to 40 wt% based on the total weight of the particulate component , especially tea .
- the sachet further comprises an ingredient selected from sugar, protein, fat , colouring agent , flavouring agent , antioxidant , health benefit agents such as vitamins, minerals , petides , thickener, or a combination thereof .
- these optional ingredients are included in the aqueous phase or partly in the sachet and partly in the aqueous phase of the final beverage .
- the plant sterol or its ester and the emulsifier are melted to a temperature of at least 50 0 C before they are included in the sachet .
- the composition of plant sterol and emulsifier is cooled before combining it with the other ingredients but this is not required .
- the plant sterol and emulsifier are melted to a temperature from 50 to 80 0 C, preferably from 55 to 70 0 C before they are combined with the other components .
- the sachet is infused with water .
- the water is preferably hot water having a temperature from 60 to 100 0 C .
- the infusion may be done by immersing the sachet in water, heating water wherein the sachet is placed in a microwave , or by any other suitable method .
- the invention relates to the use of a sachet according to the invention for the preparation of a beverage, especially tea .
- the sachet comprises herbs or other taste or flavour components as the particulate component and is immersed in water that is used for cooking rice or noodles or any other composition.
- the immersing in this water will lead to a release of the herb or flavour components into the product that is cooked, together with a release of the plant sterols .
- the particulate material is merely a filler material used to provide some weight to the sachet .
- examples of such particulate material are fibres , porous material or insoluble salts such as CaCO 3 .
- the sachet is sold in combination with a separately- packed aqueous phase that optionally comprises further ingredients such as health benefit agents , flavouring composition, colouring agents . Therefore in another aspect the invention relates to a kit of parts comprising a sachet according to the invention and a separate packaging comprising an aqueous composition.
- the invention is illustrated by the following non limiting examples .
- the surface weighted mean diameter D [3 , 2] and volume weighted mean diameter D [4 , 3] droplet sizes of the sterol esters are given in table 1.
- the tea sterol ester/ tween 60TM mixture was prepared in the same way as described in example 1. The mixture was put into an empty LiptonTM tea bag . The bag was closed. The bag was immersed in hot water (85 °C) and moved slowly up and down in the water for several times . The tea drink was allowed to cool at room temperature . The bag was left in the tea drink.
- Comparative Example 2 A drink was prepared in the same way as described in comparative example 1 , however in this case no tea leaves were added to the mixture of sterol esters and tween 60TM . In this comparative example the sterolester/TweenTM composition was not in a sachet .
- Comparative Example 3 A drink was prepared in the same way as described in example 1 , however in this case no tea leaves were added to the mixture of sterol esters and tween 60TM . Visual evaluation showed the quick formation of an unacceptable amount of sterol esters droplets on the surface .
- the average droplet size of the sterol esters expressed as D [3 , 2] and D [4 , 3] are given in table 4.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Non-Alcoholic Beverages (AREA)
- Tea And Coffee (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05814292A EP1835819A1 (en) | 2005-01-14 | 2005-11-18 | Sachets comprising plant sterol |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05075107 | 2005-01-14 | ||
EP05814292A EP1835819A1 (en) | 2005-01-14 | 2005-11-18 | Sachets comprising plant sterol |
PCT/EP2005/012500 WO2006074752A1 (en) | 2005-01-14 | 2005-11-18 | Sachets comprising plant sterol |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1835819A1 true EP1835819A1 (en) | 2007-09-26 |
Family
ID=34937997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05814292A Withdrawn EP1835819A1 (en) | 2005-01-14 | 2005-11-18 | Sachets comprising plant sterol |
Country Status (6)
Country | Link |
---|---|
US (1) | US20080206407A1 (en) |
EP (1) | EP1835819A1 (en) |
AU (1) | AU2005324945A1 (en) |
BR (1) | BRPI0517590A (en) |
WO (1) | WO2006074752A1 (en) |
ZA (1) | ZA200705739B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102013011271B4 (en) | 2012-07-05 | 2019-05-09 | Papierindustrie Maasmond B.V. | Improved sealed paper bag made from recycled soda kraft paper |
WO2016142745A1 (en) | 2015-03-11 | 2016-09-15 | Tubitak | Water dispersible sterol/stanol enriched polyphenol rich herbal teas in aqueous or powdered forms to reduce total and ldl cholesterol levels |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL314271A1 (en) * | 1993-11-08 | 1996-09-02 | Unilever Nv | Infusion bag |
IN185730B (en) * | 1998-02-19 | 2001-04-14 | Mcneil Ppc Inc | |
US6372270B1 (en) * | 1999-05-26 | 2002-04-16 | Sean P. Denny | Drink mix apparatus for making personal quantities of beverage |
JP2003520204A (en) * | 1999-11-04 | 2003-07-02 | モンサント テクノロジー エルエルシー | Cholesterol lowering stanol composition, preparation and use |
WO2002031263A1 (en) * | 2000-10-09 | 2002-04-18 | Dynamic Products Limited | A beverage infusion package with improved freshness and reduced dusting |
US7090863B2 (en) * | 2001-11-30 | 2006-08-15 | Inpharma S.A. | Hypocholesterolemic composition and methods of use |
AU2003241478A1 (en) * | 2002-06-10 | 2003-12-22 | Elan Pharma International, Ltd. | Nanoparticulate sterol formulations and sterol combinations |
US20040253327A1 (en) * | 2003-06-12 | 2004-12-16 | Niazi Sarfaraz K. | Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides, and sugar and preventing or treating cardiovascular diseases |
US20050031761A1 (en) * | 2003-08-05 | 2005-02-10 | Donald Brucker | Methods of producing a functionalized coffee |
-
2005
- 2005-11-18 EP EP05814292A patent/EP1835819A1/en not_active Withdrawn
- 2005-11-18 AU AU2005324945A patent/AU2005324945A1/en not_active Abandoned
- 2005-11-18 US US11/795,155 patent/US20080206407A1/en not_active Abandoned
- 2005-11-18 WO PCT/EP2005/012500 patent/WO2006074752A1/en active Application Filing
- 2005-11-18 ZA ZA200705739A patent/ZA200705739B/en unknown
- 2005-11-18 BR BRPI0517590-9A patent/BRPI0517590A/en not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO2006074752A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2005324945A1 (en) | 2006-07-20 |
US20080206407A1 (en) | 2008-08-28 |
ZA200705739B (en) | 2009-01-28 |
WO2006074752A1 (en) | 2006-07-20 |
BRPI0517590A (en) | 2008-10-14 |
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