EP1825144A2 - Schlauchpumpe - Google Patents

Schlauchpumpe

Info

Publication number
EP1825144A2
EP1825144A2 EP05794814A EP05794814A EP1825144A2 EP 1825144 A2 EP1825144 A2 EP 1825144A2 EP 05794814 A EP05794814 A EP 05794814A EP 05794814 A EP05794814 A EP 05794814A EP 1825144 A2 EP1825144 A2 EP 1825144A2
Authority
EP
European Patent Office
Prior art keywords
membrane
peristaltic pump
groove
pump according
anyone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05794814A
Other languages
English (en)
French (fr)
Other versions
EP1825144B1 (de
Inventor
Florent Junod
Frédéric Neftel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debiotech SA
Original Assignee
Debiotech SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiotech SA filed Critical Debiotech SA
Priority to EP05794814A priority Critical patent/EP1825144B1/de
Publication of EP1825144A2 publication Critical patent/EP1825144A2/de
Application granted granted Critical
Publication of EP1825144B1 publication Critical patent/EP1825144B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00Machines, pumps, or pumping installations having flexible working members
    • F04B43/12Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/14Machines, pumps, or pumping installations having flexible working members having peristaltic action having plate-like flexible members
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00Machines, pumps, or pumping installations having flexible working members
    • F04B43/12Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F04B43/1269Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing the rotary axes of the rollers lying in a plane perpendicular to the rotary axis of the driving motor
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00Fluid parameters
    • F04B2205/01Pressure before the pump inlet
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00Fluid parameters
    • F04B2205/05Pressure after the pump outlet

Definitions

  • the present invention relates to a peristaltic pump which may be used in the medical field, e.g. administration of drugs or of contrast media, peritoneal dialysis, etc...
  • the invention relates to a peristaltic pump of the "membrane" type.
  • Peristaltic pumps of the "membrane" type comprise a pumping cavity covered by a flexible membrane. Fluid is moved in the cavity by a moving pressure wave applied to the membrane.
  • the pressure wave can be obtained by a plurality of pressure elements situated along the cavity or by one or some moving pressure elements.
  • the fluid When the cavity contains an inlet and an outlet, the fluid has to be directed along a specific path (the pumping path). To this effect, a sealing element has to be placed between the inlet and the outlet.
  • the sealing element is made of a ridge forming part of the membrane.
  • a pump body with a face containing at least a circular pumping cavity covered by a flexible membrane fixed to said pump body, in such a way as to form a fluid tight channel.
  • the membrane has a sealing ridge which is in permanent contact against a specific zone of the cavity so as to obtain a resting fluid tight sealing segment in the cavity,
  • a movable roller adapted to temporarily press a portion of the membrane above the cavity and form a moving sealing segment in the cavity
  • a driving shaft adapted to rotatably move the roller along the cavity.
  • the driving shaft is mounted in an axial bearing which permits the drive shaft to move axially, i.e. against the action of a spring.
  • a pump body with a face containing at least a first groove covered by a flexible membrane fixed to said pump body, in such a way as to form a fluid tight channel, said membrane furthermore comprising a sealing ridge which is in permanent contact against said groove so as to obtain a resting fluid tight sealing segment in the channel,
  • a movable pressure element adapted to temporarily press a portion of the membrane above said groove and form a moving sealing segment in the channel
  • the driving means are adapted to move the movable pressure element exclusively along a plane which is parallel to said pump body face, the sealing ridge and/or the groove being adapted to let said movable pressure element in said parallel plane when moving over said sealing ridge.
  • the peristaltic pump is characterized by the fact that the ball is rotatably fixed to an axis forming part of said driving means, said axis being parallel to the membrane.
  • the sealing ridge is made of an elastomeric material which allows the sealing ridge to collapse.
  • the sealing ridge is designed to reach a position which places the complete membrane external face which is pressed in the same plane.
  • the groove contains a zone of greater depth. This deeper forms a part of the permanent fluid tight sealing segment.
  • the sealing ridge being designed to tightly fill the deeper zone.
  • One preferred embodiment for fixing the membrane to the pump body consists in providing the pump body with a second groove and in providing the membrane with a second ridge.
  • the second ridge is designed to be located in the second groove and to therefore tightly fix the membrane to the pump body.
  • the movable pressure element is a ball which, preferably, is rotatably fixed to an axis forming part of the driving means.
  • the axis is parallel to the membrane.
  • the groove forms a portion of a circle.
  • the groove forms at least a complete circle.
  • the groove may contain a fluid inlet and a fluid outlet. The permanent fluid tight sealing segment being then located on the shortest distance separating said inlet from said outlet. This forces the fluid to move on the greatest distance.
  • the groove may consist of a complete circle and two connected branches, one branch containing the inlet and the other branch containing the outlet. If the groove has a circular or a partial circular shape, the driving means may comprise a crown with a diameter at least identical to the first groove diameter.
  • the crown is adapted to be in close contact with the membrane when the membrane is not pressed by said movable pressure element. Such a configuration ensures a more regular flow in the channel.
  • the peristaltic pump may also contain several bails which, preferably, are separated by a rigid element being in close contact with the membrane.
  • the rigid element may contain several balls of relatively small diameter which are adapted to freely rotate on the membrane when the driving means are activated.
  • the pump body face contains at least another cavity forming part of an element such as a valve, a pressure sensor or a hub chamber.
  • the other cavity is also covered by the membrane.
  • the peristaltic pump according to the invention may be incorporated in a liquid distribution system similar to the one disclosed in international patent application PCT/CH2004/000480 filed by the applicant of the present invention.
  • the membrane is tightly fixed to the pump body.
  • the peristaltic pump comprises a pressure sensor located within the channel entry, the pressure sensor being connected to a flow compensating means, including e.g. a microprocessor, in such a way that any pressure difference recorded by said pressure sensor would adapt the fluid flow accordingly.
  • a flow compensating means including e.g. a microprocessor
  • the pressure sensor may be located within the channel exit.
  • the peristaltic pump comprises flow compensating means, based on membrane wear, which is adapted to automatically correct the fluid flow after a certain time and/or a certain number of pumping cycles.
  • FIG. 1 is a perspective view of an example of the peristaltic pump according to the invention.
  • FIG. 2 is a sectional/longitudinal view of the pump of fig. 1.
  • FIG. 3 is a perspective view from above of a ball bearing unit with balls.
  • FIG. 4 is a perspective view from bellow of the ball bearing unit of fig. 3.
  • FIG. 5 is a perspective view from above of a membrane plate.
  • FIG. 6 is a perspective view from bellow of the membrane plate of fig. 5.
  • FIG. 7 is a perspective view from above of a membrane.
  • FIG. 8 is a perspective view from bellow of the membrane of fig. 8.
  • FIG. 9 is a perspective view from a pump body.
  • FIG. 10 is a perspective view of a liquid distribution system incorporating a pump according to the invention.
  • Membrane protruding part 20 Membrane transversal ridge.
  • Figure 1 shows a pump according to the invention including all essential elements.
  • Figures 2 to 9 show some of the elements of figure 1 which are taken separately.
  • the pump body 3 contains a circular groove 4 which extends in two parallel branches 6. Each branch 6 contains an inlet or an outlet 10 through which liquid can enter or exit the circular groove 4.
  • the groove 4 and the branches 6 are covered by a membrane 2 made of flexible material.
  • the membrane 2 is covered by a membrane plate 1 which is fixed to the pump body 3.
  • the membrane is provided with an external ridge 11 and an internal ridge 12 which are located in a corresponding external groove 13 and an internal groove 14 contained in the pump body 3.
  • the membrane 2 is not covered by the membrane plate 1 in the central part and above the groove.
  • the groove 4 contains a zone of greater depth 17 having a transversal groove 5.
  • the membrane 2 On its internal face, the membrane 2 contains a protruding part 19 with a transversal ridge 20 which represents a negative reproduction of the groove deeper zone 17 and transversal groove 5.
  • This configuration forms a resting fluid sealing segment in the groove 4, i.e. in order to go from the inlet to the outlet, liquid is forced to use the groove longest path.
  • the membrane 2 On its external face, the membrane 2 contains a cavity 18 which is approximately identical in shape to the zone of greater depth 17 and the transversal groove 5.
  • a ball bearing unit 8 is rotatably positioned above the membrane central part.
  • the ball bearing unit 8 contains several freely rotating balls 7 which can freely rotate around axis 9 which are parallel to the membrane 2.
  • the ball bearing unit 8 is mounted rotatable around a vertical axis so that the balls 7 can move along the groove 4.
  • the bottom part of the ball bearing unit 8 forms a crown 15.
  • the crown segments 16 which are situated between the balls 7 are in close contact with the membrane upper face.
  • the balls 7 are moving along the groove 4 and simultaneously press the membrane 2 against the groove bottom to such an extend that a plurality of moving fluid sealing segments are created and moved from the inlet to the outlet.
  • the balls 7 When passing over the groove deeper 17 zone, i.e. the resting fluid sealing segment, the balls 7 are not vertically shifted away.
  • the balls move exclusively in the same plane thanks to the specific configuration of the groove deeper zone 17.
  • Figure 10 shows a possibility to include a pump according to the invention in a liquid distribution system, e.g. as defined in international patent application
  • the liquid distribution system may contain several cavities

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reciprocating Pumps (AREA)
  • Massaging Devices (AREA)
  • Pipe Accessories (AREA)
  • Seal Device For Vehicle (AREA)
EP05794814A 2004-11-26 2005-10-20 Schlauchpumpe Not-in-force EP1825144B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05794814A EP1825144B1 (de) 2004-11-26 2005-10-20 Schlauchpumpe

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04405736A EP1662142A1 (de) 2004-11-26 2004-11-26 Peristaltische Pumpe
EP05794814A EP1825144B1 (de) 2004-11-26 2005-10-20 Schlauchpumpe
PCT/IB2005/053443 WO2006056895A2 (en) 2004-11-26 2005-10-20 Peristaltic pump

Publications (2)

Publication Number Publication Date
EP1825144A2 true EP1825144A2 (de) 2007-08-29
EP1825144B1 EP1825144B1 (de) 2010-05-19

Family

ID=34932384

Family Applications (2)

Application Number Title Priority Date Filing Date
EP04405736A Withdrawn EP1662142A1 (de) 2004-11-26 2004-11-26 Peristaltische Pumpe
EP05794814A Not-in-force EP1825144B1 (de) 2004-11-26 2005-10-20 Schlauchpumpe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP04405736A Withdrawn EP1662142A1 (de) 2004-11-26 2004-11-26 Peristaltische Pumpe

Country Status (6)

Country Link
US (1) US20080131300A1 (de)
EP (2) EP1662142A1 (de)
JP (1) JP4880613B2 (de)
AT (1) ATE468488T1 (de)
DE (1) DE602005021396D1 (de)
WO (1) WO2006056895A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007006055A2 (en) 2005-07-06 2007-01-11 Vascular Pathways Inc. Intravenous catheter insertion device and method of use
US20070248477A1 (en) 2006-03-29 2007-10-25 Alcon, Inc. Cassette having elastomeric clamping ribs
US9121509B2 (en) 2006-09-26 2015-09-01 Novartis Ag Valve that is normally closed in the free state
WO2008137956A2 (en) 2007-05-07 2008-11-13 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US8932258B2 (en) 2010-05-14 2015-01-13 C. R. Bard, Inc. Catheter placement device and method
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
JP5614114B2 (ja) * 2010-06-09 2014-10-29 セイコーエプソン株式会社 流体輸送装置
WO2014123600A2 (en) * 2012-12-10 2014-08-14 Vanderbilt University Normally closed microvalve and applications of the same
US10078075B2 (en) 2011-12-09 2018-09-18 Vanderbilt University Integrated organ-on-chip systems and applications of the same
EP2625425A2 (de) * 2010-10-07 2013-08-14 Vanderbilt University Peristaltische mikropumpe sowie zugehörige systeme und verfahren
US9618129B2 (en) * 2010-10-07 2017-04-11 Vanderbilt University Normally closed microvalve and applications of the same
EP2441485A1 (de) * 2010-10-13 2012-04-18 Fresenius Kabi Deutschland GmbH Pumpenmodul, Pumpenbasismodul und Pumpenssystem
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
ES2835652T3 (es) 2011-02-25 2021-06-22 Bard Inc C R Dispositivo de inserción de componente médico que incluye una aguja retraíble
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
CN103608589A (zh) * 2011-06-17 2014-02-26 西门子医疗保健诊断公司 面驱动流体泵
CA2849486C (en) 2011-09-21 2017-12-12 Bayer Medical Care Inc. Continuous multi-fluid pump device, drive and actuating system, and method
DE102011114468B4 (de) * 2011-09-28 2016-08-11 Carl Zeiss Meditec Ag Ophthalmochirurgische Kassette
US9522254B2 (en) 2013-01-30 2016-12-20 Vascular Pathways, Inc. Systems and methods for venipuncture and catheter placement
US9291159B2 (en) 2013-05-30 2016-03-22 Novartis Ag Pump head with independently sprung offset picoting rollers
US10041488B2 (en) * 2013-05-30 2018-08-07 Novartis Ag Pump roller assembly with independently sprung rollers
US9797391B2 (en) * 2013-05-30 2017-10-24 Novartis Ag Pump roller assembly with independently sprung pivoting rollers
US9624921B2 (en) * 2013-05-30 2017-04-18 Novartis Ag Pump roller head with pivoting rollers and spring arms
US9797390B2 (en) * 2013-05-30 2017-10-24 Novartis Ag Pump roller assembly with flexible arms
WO2016037127A1 (en) 2014-09-05 2016-03-10 C.R. Bard, Inc. Catheter insertion device including retractable needle
KR20240064764A (ko) 2015-01-09 2024-05-13 바이엘 헬쓰케어 엘엘씨 다회 사용 1회용 세트를 갖는 다중 유체 전달 시스템 및 그 특징부
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
JP7016261B2 (ja) 2015-05-15 2022-02-21 シー・アール・バード・インコーポレーテッド 延出可能な針安全構成要素を含むカテーテル留置装置
US10690127B2 (en) 2016-08-30 2020-06-23 Alcon Inc. Handheld ophthalmic probe with peristaltic pump and associated devices, systems, and methods
CN112206397B (zh) 2016-09-12 2023-03-21 C·R·巴德股份有限公司 导管插入装置的血液控制
US10138881B2 (en) * 2016-12-27 2018-11-27 Piranha Plastics, Llc Fluid pump with pulse reduction
JP6953541B2 (ja) 2017-03-01 2021-10-27 シー・アール・バード・インコーポレーテッドC R Bard Incorporated カテーテル挿入装置
US11389626B2 (en) 2018-03-07 2022-07-19 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
CN108894963A (zh) * 2018-07-19 2018-11-27 佛山市雅科奇电子电器有限公司 一种旋液泵
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
WO2020264475A1 (en) * 2019-06-28 2020-12-30 Vanderbilt University Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same
US11786401B2 (en) 2019-03-18 2023-10-17 Verily Life Sciences Llc Peristaltic micropump assemblies and associated devices, systems, and methods
CN213312819U (zh) 2019-08-19 2021-06-01 贝克顿·迪金森公司 中线导管放置装置
WO2023244610A1 (en) * 2022-06-13 2023-12-21 Bristol-Myers Squibb Company Peristaltic pump

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2671412A (en) * 1948-09-02 1954-03-09 Flexible Pumps Inc Collapsible chamber pump with rotary compress
US2841091A (en) * 1953-11-16 1958-07-01 Schaurte Paul Apparatus for conveying gases or liquids
GB782105A (en) * 1953-11-16 1957-09-04 Paul Schaurte Apparatus for conveying gases or liquids
US2920815A (en) * 1954-08-04 1960-01-12 Schaurte Paul Apparatus for conveying gases or liquids
DE960490C (de) * 1954-08-05 1957-03-21 Paul Schaurte Einrichtung zum Umwaelzen von Gasen oder Fluessigkeiten
US2920578A (en) * 1955-04-29 1960-01-12 Schaurte Paul Apparatus for conveying gases or liquids
GB790161A (en) * 1956-01-13 1958-02-05 Paul Schaurte Rotary pumping apparatus for conveying gases or liquids
US3440966A (en) * 1967-08-29 1969-04-29 Gen Motors Corp Transfer pump
US3669578A (en) * 1970-09-21 1972-06-13 Frank J Nameny Pumping apparatus
US3922119A (en) * 1971-10-20 1975-11-25 Amrose Corp Peristalitic diaphragm pump structure
FR2200907A5 (de) * 1972-09-26 1974-04-19 Meffre Jean Mar E
US4394862A (en) * 1980-08-25 1983-07-26 Baxter Travenol Laboratories, Inc. Metering apparatus with downline pressure monitoring system
US4798580A (en) * 1987-04-27 1989-01-17 Site Microsurgical Systems, Inc. Disposable peristaltic pump cassette system
FR2644212B1 (fr) * 1989-03-13 1991-11-15 Malbec Edouard Cassette pour pompe peristaltique a tube deformable, et pompe peristaltique equipee d'une telle cassette
DE4244619A1 (de) * 1992-12-31 1994-07-07 Knf Neuberger Gmbh Verfahren zum Betreiben einer Membranpumpe sowie Membranpumpe zum Durchführen des Verfahrens
US5840069A (en) * 1996-04-04 1998-11-24 Medtronic, Inc. Implantable peristaltic pump techniques
DE19922612C2 (de) * 1999-05-17 2001-05-23 Fraunhofer Ges Forschung Mikromechanische Pumpe
US6293926B1 (en) * 1999-11-10 2001-09-25 Alcon Universal Ltd. Peristaltic pump and cassette
US6296460B1 (en) * 2000-03-01 2001-10-02 Steve C. Smith Rotary cavity pump
JP3424681B1 (ja) * 2001-09-12 2003-07-07 セイコーエプソン株式会社 液体吐出装置及び液体吐出装置を備えた機器

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2006056895A2 *

Also Published As

Publication number Publication date
DE602005021396D1 (de) 2010-07-01
EP1662142A1 (de) 2006-05-31
JP2008522076A (ja) 2008-06-26
EP1825144B1 (de) 2010-05-19
WO2006056895A2 (en) 2006-06-01
US20080131300A1 (en) 2008-06-05
WO2006056895A3 (en) 2007-08-16
JP4880613B2 (ja) 2012-02-22
ATE468488T1 (de) 2010-06-15

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