EP1784502A4 - Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau - Google Patents

Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau

Info

Publication number
EP1784502A4
EP1784502A4 EP05769351A EP05769351A EP1784502A4 EP 1784502 A4 EP1784502 A4 EP 1784502A4 EP 05769351 A EP05769351 A EP 05769351A EP 05769351 A EP05769351 A EP 05769351A EP 1784502 A4 EP1784502 A4 EP 1784502A4
Authority
EP
European Patent Office
Prior art keywords
imaging
water
semiconductor nanocrystals
biological detection
fluorescent lifetime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05769351A
Other languages
German (de)
English (en)
Other versions
EP1784502A2 (fr
Inventor
Wei Liu
Zuoyan Peng
Michael Locascio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evident Technologies Inc
Original Assignee
Evident Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/885,867 external-priority patent/US7192780B2/en
Application filed by Evident Technologies Inc filed Critical Evident Technologies Inc
Publication of EP1784502A2 publication Critical patent/EP1784502A2/fr
Publication of EP1784502A4 publication Critical patent/EP1784502A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP05769351A 2004-07-08 2005-07-08 Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau Withdrawn EP1784502A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/885,867 US7192780B2 (en) 2002-10-23 2004-07-08 Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals
PCT/US2005/024211 WO2006014576A2 (fr) 2002-10-23 2005-07-08 Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau

Publications (2)

Publication Number Publication Date
EP1784502A2 EP1784502A2 (fr) 2007-05-16
EP1784502A4 true EP1784502A4 (fr) 2007-10-03

Family

ID=37872031

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05769351A Withdrawn EP1784502A4 (fr) 2004-07-08 2005-07-08 Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau

Country Status (2)

Country Link
EP (1) EP1784502A4 (fr)
CA (1) CA2573150A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115817A1 (en) * 2002-10-23 2004-06-17 Wei Liu Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115817A1 (en) * 2002-10-23 2004-06-17 Wei Liu Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALIVISATOS PAUL: "The use of nanocrystals in biological detection.", NATURE BIOTECHNOLOGY, vol. 22, no. 1, January 2004 (2004-01-01), pages 47 - 52, XP002446195, ISSN: 1087-0156 *
DAHAN M ET AL: "TIME-GATED BIOLOGICAL IMAGING BY USE OF COLLOIDAL QUANTUM DOTS", OPTICS LETTERS, OSA, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC, US, vol. 26, no. 11, 1 June 2001 (2001-06-01), pages 825 - 827, XP001103014, ISSN: 0146-9592 *
LAKOWICZ JOSEPH R ET AL: "Time-resolved spectral observations of cadmium-enriched cadmium sulfide nanoparticles and the effects of DNA oligomer binding", ANALYTICAL BIOCHEMISTRY, vol. 280, no. 1, 10 April 2000 (2000-04-10), pages 128 - 136, XP002446376, ISSN: 0003-2697 *
See also references of WO2006014576A2 *
WU X ET AL: "IMMUNOFLUORESCENT LABELING OF CANCER MARKER HER2 AND OTHER CELLULAR TARGETS WITH SEMICONDUCTOR QUANTUM DOTS", NATURE BIOTECHNOLOGY, NATURE PUB. CO, NEW YORK, NY, US, vol. 21, January 2003 (2003-01-01), pages 41 - 46, XP008053284, ISSN: 1087-0156 *

Also Published As

Publication number Publication date
CA2573150A1 (fr) 2006-02-09
EP1784502A2 (fr) 2007-05-16

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