EP1755677A4 - Hochdruck-sprühtrocknung bioaktiver materialien - Google Patents

Hochdruck-sprühtrocknung bioaktiver materialien

Info

Publication number
EP1755677A4
EP1755677A4 EP05770439A EP05770439A EP1755677A4 EP 1755677 A4 EP1755677 A4 EP 1755677A4 EP 05770439 A EP05770439 A EP 05770439A EP 05770439 A EP05770439 A EP 05770439A EP 1755677 A4 EP1755677 A4 EP 1755677A4
Authority
EP
European Patent Office
Prior art keywords
dry
high pressure
pressure spray
bioactive materials
bioactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05770439A
Other languages
English (en)
French (fr)
Other versions
EP1755677A2 (de
Inventor
Vu Truong-Le
Tom Scherer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedImmune LLC
Original Assignee
MedImmune Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MedImmune Vaccines Inc filed Critical MedImmune Vaccines Inc
Publication of EP1755677A2 publication Critical patent/EP1755677A2/de
Publication of EP1755677A4 publication Critical patent/EP1755677A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP05770439A 2004-06-14 2005-06-13 Hochdruck-sprühtrocknung bioaktiver materialien Withdrawn EP1755677A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57985004P 2004-06-14 2004-06-14
PCT/US2005/020792 WO2005123131A2 (en) 2004-06-14 2005-06-13 High pressure spray-dry of bioactive materials

Publications (2)

Publication Number Publication Date
EP1755677A2 EP1755677A2 (de) 2007-02-28
EP1755677A4 true EP1755677A4 (de) 2009-11-25

Family

ID=35510270

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05770439A Withdrawn EP1755677A4 (de) 2004-06-14 2005-06-13 Hochdruck-sprühtrocknung bioaktiver materialien

Country Status (5)

Country Link
EP (1) EP1755677A4 (de)
JP (1) JP2008505192A (de)
AU (1) AU2005254062B2 (de)
CA (1) CA2564791A1 (de)
WO (1) WO2005123131A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2072040B1 (de) 2004-05-12 2013-05-01 Baxter International Inc. Therapeutische Verwendung von Nukleinsäure-Mikrokügelchen
CN103432079A (zh) 2004-05-12 2013-12-11 巴克斯特国际公司 含有寡核苷酸的微球体及其在制备用于治疗1型糖尿病的药物中的应用
EP1834651A1 (de) * 2006-03-15 2007-09-19 Universiteit Gent Vakzin-Zusammensetzung und Verfahren zur Vakzin-Herstellung für veterinäre Krankheiten
US8268354B2 (en) * 2007-11-07 2012-09-18 Aridis Pharmaceuticals Sonic low pressure spray drying
US9616117B2 (en) 2008-10-02 2017-04-11 Pharmathene, Inc. Anthrax vaccine formulation and uses thereof
WO2010135495A2 (en) * 2009-05-20 2010-11-25 Aeras Global Tb Vaccine Foundation Stable, spray dried, immunogenic, viral compositions
BR112012021576A2 (pt) 2010-02-26 2016-10-25 Novo Nordisk As composições estáveis contendo anticorpo.
DK2542257T3 (en) 2010-03-01 2017-10-16 Bayer Healthcare Llc OPTIMIZED MONOCLONAL ANTIBODIES AGAINST Tissue FACTOR ROAD INHIBITOR (TFPI)
AU2011257219B2 (en) 2010-05-28 2014-12-04 Novo Nordisk A/S Stable multi-dose compositions comprising an antibody and a preservative
EP2691415B1 (de) * 2011-03-28 2018-07-11 Ablynx N.V. Verfahren zur herstellung fester formulierungen mit variablen immunglobulin-einzeldomänen
ITMI20112042A1 (it) * 2011-11-10 2013-05-11 Eratech S R L Polvere da ricostituire prima dell'uso comprendente melatonina e preparazione iniettabile ottenibile da tale polvere.
US9592297B2 (en) 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
BR112015024868A2 (pt) * 2013-03-28 2017-07-18 Instillo Gmbh método para produzir dispersões e matérias sólidas através de precipitação, coprecipitação e processo de auto-organização controlados e método para produzir dispersões e matérias sólidas através de precipitação controlada, coprecipitação e processo de auto-organização em um reator de microjato
US20190247303A1 (en) * 2016-10-31 2019-08-15 Vectura Limited Inhalable powder composition comprising il-13 antibody
EP3459529A1 (de) * 2017-09-20 2019-03-27 Tillotts Pharma Ag Herstellung von festen darreichungsformen mit verzögerter freisetzung mit antikörpern durch sprühtrocknung
GB201718888D0 (en) * 2017-11-15 2017-12-27 Ucb Biopharma Sprl Method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531580B1 (en) * 1999-06-24 2003-03-11 Ixsys, Inc. Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
US20030091584A1 (en) * 2000-11-28 2003-05-15 Young James F. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
WO2003087335A2 (en) * 2002-04-11 2003-10-23 Medimmune Vaccines, Inc. Preservation of bioactive materials by spray drying
WO2004058156A2 (en) * 2002-12-17 2004-07-15 Medimmune Vaccines, Inc. High pressure spray-dry of bioactive materials

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0913177A1 (de) * 1997-11-03 1999-05-06 Roche Diagnostics GmbH Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung
AU2003230908A1 (en) * 2002-04-11 2003-10-27 Medimmune Vaccines, Inc. Spray freeze dry of compositions for intranasal administration
US7923029B2 (en) * 2002-04-11 2011-04-12 Medimmune Llc Spray freeze dry of compositions for pulmonary administration

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531580B1 (en) * 1999-06-24 2003-03-11 Ixsys, Inc. Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
US20030091584A1 (en) * 2000-11-28 2003-05-15 Young James F. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
WO2003087335A2 (en) * 2002-04-11 2003-10-23 Medimmune Vaccines, Inc. Preservation of bioactive materials by spray drying
WO2004058156A2 (en) * 2002-12-17 2004-07-15 Medimmune Vaccines, Inc. High pressure spray-dry of bioactive materials

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BREEN E D ET AL: "Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation", PHARMACEUTICAL RESEARCH 2001 US, vol. 18, no. 9, 2001, pages 1345 - 1353, XP002550626, ISSN: 0724-8741 *

Also Published As

Publication number Publication date
JP2008505192A (ja) 2008-02-21
WO2005123131A2 (en) 2005-12-29
EP1755677A2 (de) 2007-02-28
AU2005254062A1 (en) 2005-12-29
CA2564791A1 (en) 2005-12-29
AU2005254062B2 (en) 2011-02-17
WO2005123131A3 (en) 2008-01-03

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20061204

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR LV MK YU

DAX Request for extension of the european patent (deleted)
PUAK Availability of information related to the publication of the international search report

Free format text: ORIGINAL CODE: 0009015

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/715 20060101ALI20080122BHEP

Ipc: A61K 9/14 20060101ALI20080122BHEP

Ipc: A61K 39/215 20060101ALI20080122BHEP

Ipc: A61K 39/155 20060101ALI20080122BHEP

Ipc: A61K 39/12 20060101AFI20080122BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20091028

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: MEDIMMUNE, LLC

17Q First examination report despatched

Effective date: 20100421

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120417