EP1718669A4 - IDENTIFICATION OF NEW IGE EPITOPES - Google Patents
IDENTIFICATION OF NEW IGE EPITOPESInfo
- Publication number
- EP1718669A4 EP1718669A4 EP04779424A EP04779424A EP1718669A4 EP 1718669 A4 EP1718669 A4 EP 1718669A4 EP 04779424 A EP04779424 A EP 04779424A EP 04779424 A EP04779424 A EP 04779424A EP 1718669 A4 EP1718669 A4 EP 1718669A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- identification
- ige epitopes
- novel ige
- novel
- epitopes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2004/002894 WO2004070011A2 (en) | 2003-02-01 | 2004-02-02 | HIGH AFFINITY ANTI-HUMAN IgE ANTIBODIES |
PCT/US2004/002892 WO2004070010A2 (en) | 2003-02-01 | 2004-02-02 | A method for generating high affinity antibodies |
PCT/US2004/024360 WO2005075504A1 (en) | 2004-02-02 | 2004-07-29 | IDENTIFICATION OF NOVEL IgE EPITOPES |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1718669A1 EP1718669A1 (en) | 2006-11-08 |
EP1718669A4 true EP1718669A4 (en) | 2007-10-10 |
Family
ID=34841291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04779424A Withdrawn EP1718669A4 (en) | 2004-02-02 | 2004-07-29 | IDENTIFICATION OF NEW IGE EPITOPES |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1718669A4 (ko) |
JP (1) | JP2008507474A (ko) |
KR (4) | KR101365375B1 (ko) |
CN (1) | CN102702359A (ko) |
AU (2) | AU2004315197B2 (ko) |
CA (1) | CA2552999A1 (ko) |
SG (2) | SG149892A1 (ko) |
WO (1) | WO2005075504A1 (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009545330A (ja) * | 2006-08-04 | 2009-12-24 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ぺンシルべニア | Ige依存性疾患を治療するための方法および組成物 |
US7833527B2 (en) * | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
AR065368A1 (es) * | 2007-02-15 | 2009-06-03 | Astrazeneca Ab | Anticuerpos para moleculas de ige |
JP2010519194A (ja) * | 2007-02-15 | 2010-06-03 | アストラゼネカ・アクチエボラーグ | IgE分子に対する結合要素 |
EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
AP2010005296A0 (en) * | 2007-12-21 | 2010-06-30 | Glaxosmithkline Biolog Sa | Vaccines for malaria |
EP2376108B1 (en) | 2008-12-09 | 2017-02-22 | Pfizer Vaccines LLC | IgE CH3 PEPTIDE VACCINE |
CA2800774A1 (en) | 2010-06-07 | 2011-12-15 | Pfizer Vaccines Llc | Ige ch3 peptide vaccine |
EP3565587A4 (en) * | 2017-01-06 | 2020-12-16 | The Regents of The University of California | THERAPEUTIC ANTI-IGE ANTIBODIES AND RELATED METHODS AND COMPOSITIONS |
AU2019244666A1 (en) * | 2018-03-26 | 2020-10-08 | Novartis Ag | Methods of treating chronic spontaneous urticaria using ligelizumab |
EP4355362A1 (en) | 2021-06-14 | 2024-04-24 | Novartis AG | Pharmaceutical formulation containing an anti-ige antibody |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0263655A2 (en) * | 1986-10-03 | 1988-04-13 | Dainippon Pharmaceutical Co., Ltd. | Novel peptides having antiallergic activity |
EP0957111A2 (en) * | 1998-04-09 | 1999-11-17 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
WO2000023477A2 (en) * | 1998-10-20 | 2000-04-27 | University Of Sheffield | Immunoglobulin variants |
WO2000050461A1 (en) * | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses |
WO2000074716A2 (en) * | 1999-06-08 | 2000-12-14 | Smithkline Beecham Biologicals S.A. | Ige peptides for allergy immunotherapy |
WO2002016409A2 (en) * | 2000-08-22 | 2002-02-28 | Glaxosmithkline Biologicals S.A. | Vaccine immunogens comprising disulphide bridged cyclised peptide and use thereof in the treatment of allergies |
EP1195161A2 (en) * | 2000-08-30 | 2002-04-10 | Pfizer Products Inc. | Anti-IgE vaccines |
WO2002034288A2 (en) * | 2000-10-27 | 2002-05-02 | Smithkline Beecham Biologicals S.A. | Vaccine for treating allergy |
EP1262491A2 (en) * | 2001-05-22 | 2002-12-04 | Pfizer Products Inc. | Non-anaphylactogenic IgE vaccines |
WO2003092714A2 (en) * | 2002-04-30 | 2003-11-13 | Glaxosmithkline Biologicals S.A. | Peptide variants of ige constrained by beta-lactam bond |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
DK0589840T3 (da) * | 1992-09-24 | 2004-07-26 | Novartis Ag | Omdannede monoklonale antistoffer mod en immunoglobulinisotype |
US6172213B1 (en) * | 1997-07-02 | 2001-01-09 | Genentech, Inc. | Anti-IgE antibodies and method of improving polypeptides |
US7393529B2 (en) * | 1998-04-09 | 2008-07-01 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
TWI227241B (en) * | 1998-06-20 | 2005-02-01 | United Biomedical Inc | IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate |
CN1829806A (zh) * | 2003-02-01 | 2006-09-06 | 唐纳士公司 | 产生高亲和力抗体的方法 |
-
2004
- 2004-07-29 AU AU2004315197A patent/AU2004315197B2/en not_active Expired
- 2004-07-29 CA CA002552999A patent/CA2552999A1/en not_active Abandoned
- 2004-07-29 SG SG200900706-3A patent/SG149892A1/en unknown
- 2004-07-29 JP JP2006551035A patent/JP2008507474A/ja active Pending
- 2004-07-29 KR KR1020127009917A patent/KR101365375B1/ko active IP Right Grant
- 2004-07-29 WO PCT/US2004/024360 patent/WO2005075504A1/en active Application Filing
- 2004-07-29 EP EP04779424A patent/EP1718669A4/en not_active Withdrawn
- 2004-07-29 KR KR1020137018993A patent/KR101562114B1/ko active IP Right Grant
- 2004-07-29 KR KR1020147000238A patent/KR101581659B1/ko active IP Right Grant
- 2004-07-29 SG SG2012057212A patent/SG183683A1/en unknown
- 2004-07-29 KR KR1020067017609A patent/KR20070008578A/ko not_active IP Right Cessation
- 2004-07-29 CN CN2011103434066A patent/CN102702359A/zh active Pending
-
2009
- 2009-06-16 AU AU2009202408A patent/AU2009202408A1/en not_active Abandoned
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0263655A2 (en) * | 1986-10-03 | 1988-04-13 | Dainippon Pharmaceutical Co., Ltd. | Novel peptides having antiallergic activity |
EP0957111A2 (en) * | 1998-04-09 | 1999-11-17 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
WO2000023477A2 (en) * | 1998-10-20 | 2000-04-27 | University Of Sheffield | Immunoglobulin variants |
WO2000050461A1 (en) * | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses |
WO2000074716A2 (en) * | 1999-06-08 | 2000-12-14 | Smithkline Beecham Biologicals S.A. | Ige peptides for allergy immunotherapy |
WO2002016409A2 (en) * | 2000-08-22 | 2002-02-28 | Glaxosmithkline Biologicals S.A. | Vaccine immunogens comprising disulphide bridged cyclised peptide and use thereof in the treatment of allergies |
EP1195161A2 (en) * | 2000-08-30 | 2002-04-10 | Pfizer Products Inc. | Anti-IgE vaccines |
WO2002034288A2 (en) * | 2000-10-27 | 2002-05-02 | Smithkline Beecham Biologicals S.A. | Vaccine for treating allergy |
EP1262491A2 (en) * | 2001-05-22 | 2002-12-04 | Pfizer Products Inc. | Non-anaphylactogenic IgE vaccines |
WO2003092714A2 (en) * | 2002-04-30 | 2003-11-13 | Glaxosmithkline Biologicals S.A. | Peptide variants of ige constrained by beta-lactam bond |
Non-Patent Citations (3)
Title |
---|
CHANG T W ET AL: "MONOCLONAL ANTIBODIES SPECIFIC FOR HUMAN IGE-PRODUCING B CELLS A POTENTIAL THERAPEUTIC FOR IGE-MEDIATED ALLERGIC DISEASES", BIO-TECHNOLOGY (NEW YORK), vol. 8, no. 2, 1990, pages 122 - 126, XP009084134, ISSN: 0733-222X * |
MACGLASHAN D W ET AL: "DOWN-REGULATION OF FCEPSILONRI EXPRESSION ON HUMAN BASOPHILS DURINGIN VIVO TREATMENT OF ATOPIC PATIENTS WITH ANTI-IGE ANTIBODY", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 158, 1997, pages 1438 - 1445, XP002930932, ISSN: 0022-1767 * |
See also references of WO2005075504A1 * |
Also Published As
Publication number | Publication date |
---|---|
KR101562114B1 (ko) | 2015-11-20 |
SG149892A1 (en) | 2009-02-27 |
KR20120056297A (ko) | 2012-06-01 |
AU2009202408A1 (en) | 2009-07-09 |
KR20140021058A (ko) | 2014-02-19 |
CA2552999A1 (en) | 2005-08-18 |
AU2004315197A1 (en) | 2005-08-18 |
KR20130088198A (ko) | 2013-08-07 |
KR101365375B1 (ko) | 2014-02-19 |
EP1718669A1 (en) | 2006-11-08 |
KR20070008578A (ko) | 2007-01-17 |
KR101581659B1 (ko) | 2015-12-31 |
SG183683A1 (en) | 2012-09-27 |
JP2008507474A (ja) | 2008-03-13 |
AU2004315197B2 (en) | 2009-06-04 |
CN102702359A (zh) | 2012-10-03 |
WO2005075504A1 (en) | 2005-08-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20060824 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL HR LT LV MK |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20070912 |
|
17Q | First examination report despatched |
Effective date: 20090407 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20130625 |